3nva - Revision history

OCA at 16:51, 1 November 2023

2023-11-01T16:51:46Z

←Older revision		Revision as of 16:51, 1 November 2023
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	==Dimeric form of CTP synthase from Sulfolobus solfataricus==		==Dimeric form of CTP synthase from Sulfolobus solfataricus==
-	<StructureSection load='3nva' size='340' side='right' caption='[[3nva]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='3nva' size='340' side='right'caption='[[3nva]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nva]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~'saccharolobus_solfataricus' 'saccharolobus~~ solfataricus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3NVA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nva]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NVA FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>pyrG, SSO0201 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id~~=2287 'Saccharolobus solfataricus'])</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.504Å</td></tr>
-	~~<tr id='activity'><td class~~="~~sblockLbl~~">~~<b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>~~[~~http://en.wikipedia.org/wiki/CTP_synthase_(glutamine_hydrolyzing) CTP synthase (glutamine hydrolyzing)~~]~~, with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.~~2 6.~~3.4.2] </span>~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nva OCA], [https://pdbe.org/3nva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nva RCSB], [https://www.ebi.ac.uk/pdbsum/3nva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nva ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3nva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nva OCA], [~~http~~://pdbe.org/3nva PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3nva RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3nva PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3nva ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~PYRG_SULSO PYRG_SULSO]~~] Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity).	+	[https://www.uniprot.org/uniprot/PYRG_SACS2 PYRG_SACS2] Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (PubMed:21301086). Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates (By similarity).[HAMAP-Rule:MF_01227]<ref>PMID:21301086</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Saccharolobus solfataricus]]		[[Category: Saccharolobus solfataricus]]
-	[[Category: Harris, P]]	+	[[Category: Harris P]]
-	[[Category: Jensen~~, K F~~]]	+	[[Category: Jensen KF]]
-	[[Category: Johansson, E]]	+	[[Category: Johansson E]]
-	[[Category: Lauritsen, I]]	+	[[Category: Lauritsen I]]
-	[[Category: Willemoes, M]]	+	[[Category: Willemoes M]]
-	~~[[Category: Ctp synthase activity]]~~	+
-	~~[[Category: Ligase]]~~	+
-	~~[[Category: Nucleotide binding]]~~	+
-	~~[[Category: Rossmann fold~~]]	+

OCA at 07:34, 23 May 2018

2018-05-23T07:34:29Z

←Older revision		Revision as of 07:34, 23 May 2018
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	<StructureSection load='3nva' size='340' side='right' caption='[[3nva]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='3nva' size='340' side='right' caption='[[3nva]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nva]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Atcc_35091 Atcc 35091~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NVA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nva]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/'saccharolobus_solfataricus' 'saccharolobus solfataricus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NVA FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pyrG, SSO0201 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ~~ATCC 35091~~])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pyrG, SSO0201 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 'Saccharolobus solfataricus'])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP_synthase_(glutamine_hydrolyzing) CTP synthase (glutamine hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.2 6.3.4.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP_synthase_(glutamine_hydrolyzing) CTP synthase (glutamine hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.2 6.3.4.2] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nva OCA], [http://pdbe.org/3nva PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nva RCSB], [http://www.ebi.ac.uk/pdbsum/3nva PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nva ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nva OCA], [http://pdbe.org/3nva PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nva RCSB], [http://www.ebi.ac.uk/pdbsum/3nva PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nva ProSAT]</span></td></tr>
Line 14:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nv/3nva_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nv/3nva_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 33:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 35091~~]]	+	[[Category: Saccharolobus solfataricus]]
	[[Category: Harris, P]]		[[Category: Harris, P]]
	[[Category: Jensen, K F]]		[[Category: Jensen, K F]]

OCA at 12:44, 4 August 2016

2016-08-04T12:44:36Z

←Older revision		Revision as of 12:44, 4 August 2016
Line 1:		Line 1:
		+
	==Dimeric form of CTP synthase from Sulfolobus solfataricus==		==Dimeric form of CTP synthase from Sulfolobus solfataricus==
	<StructureSection load='3nva' size='340' side='right' caption='[[3nva]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='3nva' size='340' side='right' caption='[[3nva]], [[Resolution\|resolution]] 2.50Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pyrG, SSO0201 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pyrG, SSO0201 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP_synthase_(glutamine_hydrolyzing) CTP synthase (glutamine hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.2 6.3.4.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP_synthase_(glutamine_hydrolyzing) CTP synthase (glutamine hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.2 6.3.4.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nva RCSB], [http://www.ebi.ac.uk/pdbsum/3nva PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nva OCA], [http://pdbe.org/3nva PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nva RCSB], [http://www.ebi.ac.uk/pdbsum/3nva PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nva ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nva ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3nva" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 14:40, 24 December 2014

2014-12-24T14:40:47Z

←Older revision		Revision as of 14:40, 24 December 2014
Line 2:		Line 2:
	<StructureSection load='3nva' size='340' side='right' caption='[[3nva]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='3nva' size='340' side='right' caption='[[3nva]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nva]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NVA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nva]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NVA FirstGlance]. <br>
-	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP_synthase_(glutamine_hydrolyzing) CTP synthase (glutamine hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.2 6.3.4.2] </span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pyrG, SSO0201 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP_synthase_(glutamine_hydrolyzing) CTP synthase (glutamine hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.2 6.3.4.2] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nva RCSB], [http://www.ebi.ac.uk/pdbsum/3nva PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nva RCSB], [http://www.ebi.ac.uk/pdbsum/3nva PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PYRG_SULSO PYRG_SULSO]] Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 35091]]
	[[Category: Harris, P]]		[[Category: Harris, P]]
	[[Category: Jensen, K F]]		[[Category: Jensen, K F]]

OCA at 07:26, 12 November 2014

2014-11-12T07:26:52Z

←Older revision		Revision as of 07:26, 12 November 2014
Line 2:		Line 2:
	<StructureSection load='3nva' size='340' side='right' caption='[[3nva]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='3nva' size='340' side='right' caption='[[3nva]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nva]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NVA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nva]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NVA FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pyrG, SSO0201 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP_synthase_(glutamine_hydrolyzing) CTP synthase (glutamine hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.2 6.3.4.2] </span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/~~CTP_synthase~~ CTP synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.2 6.3.4.2] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nva RCSB], [http://www.ebi.ac.uk/pdbsum/3nva PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nva RCSB], [http://www.ebi.ac.uk/pdbsum/3nva PDBsum]</span></td></tr>
	</table>		</table>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	~~[[Category: CTP synthase]]~~	+	[[Category: Harris, P]]
-	~~[[Category: Sulfolobus solfataricus]]~~	+	[[Category: Jensen, K F]]
-	[[Category: Harris, P.]]	+	[[Category: Johansson, E]]
-	[[Category: Jensen, K F.]]	+	[[Category: Lauritsen, I]]
-	[[Category: Johansson, E.]]	+	[[Category: Willemoes, M]]
-	[[Category: Lauritsen, I.]]	+
-	[[Category: Willemoes, M.]]	+
	[[Category: Ctp synthase activity]]		[[Category: Ctp synthase activity]]
	[[Category: Ligase]]		[[Category: Ligase]]
	[[Category: Nucleotide binding]]		[[Category: Nucleotide binding]]
	[[Category: Rossmann fold]]		[[Category: Rossmann fold]]

OCA at 13:59, 3 November 2014

2014-11-03T13:59:09Z

←Older revision		Revision as of 13:59, 3 November 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3nva]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NVA FirstGlance]. <br>		<table><tr><td colspan='2'>[[3nva]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NVA FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pyrG, SSO0201 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pyrG, SSO0201 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP_synthase CTP synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.2 6.3.4.2] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP_synthase CTP synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.2 6.3.4.2] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nva RCSB], [http://www.ebi.ac.uk/pdbsum/3nva PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nva RCSB], [http://www.ebi.ac.uk/pdbsum/3nva PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 23:		Line 23:
	Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus.,Lauritsen I, Willemoes M, Jensen KF, Johansson E, Harris P Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Feb 1;67(Pt, 2):201-8. Epub 2011 Jan 21. PMID:21301086<ref>PMID:21301086</ref>		Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus.,Lauritsen I, Willemoes M, Jensen KF, Johansson E, Harris P Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Feb 1;67(Pt, 2):201-8. Epub 2011 Jan 21. PMID:21301086<ref>PMID:21301086</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 39:		Line 39:
	[[Category: Ligase]]		[[Category: Ligase]]
	[[Category: Nucleotide binding]]		[[Category: Nucleotide binding]]
-	[[Category: ~~Rossman~~ fold]]	+	[[Category: Rossmann fold]]

OCA at 10:24, 28 May 2014

2014-05-28T10:24:47Z

←Older revision		Revision as of 10:24, 28 May 2014
Line 1:		Line 1:
-	[[~~Image~~:3nva.~~png\|left~~\|200px]]	+	==Dimeric form of CTP synthase from Sulfolobus solfataricus==
		+	<StructureSection load='3nva' size='340' side='right' caption='[[3nva]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3nva]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NVA FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pyrG, SSO0201 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP_synthase CTP synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.2 6.3.4.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nva RCSB], [http://www.ebi.ac.uk/pdbsum/3nva PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nv/3nva_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	CTP synthase catalyzes the last committed step in de novo pyrimidine-nucleotide biosynthesis. Active CTP synthase is a tetrameric enzyme composed of a dimer of dimers. The tetramer is favoured in the presence of the substrate nucleotides ATP and UTP; when saturated with nucleotide, the tetramer completely dominates the oligomeric state of the enzyme. Furthermore, phosphorylation has been shown to regulate the oligomeric states of the enzymes from yeast and human. The crystal structure of a dimeric form of CTP synthase from Sulfolobus solfataricus has been determined at 2.5 A resolution. A comparison of the dimeric interface with the intermolecular interfaces in the tetrameric structures of Thermus thermophilus CTP synthase and Escherichia coli CTP synthase shows that the dimeric interfaces are almost identical in the three systems. Residues that are involved in the tetramerization of S. solfataricus CTP synthase according to a structural alignment with the E. coli enzyme all have large thermal parameters in the dimeric form. Furthermore, they are seen to undergo substantial movement upon tetramerization.

-	~~<!--~~	+	Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus.,Lauritsen I, Willemoes M, Jensen KF, Johansson E, Harris P Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Feb 1;67(Pt, 2):201-8. Epub 2011 Jan 21. PMID:21301086<ref>PMID:21301086</ref>
-	~~The line below this paragraph, containing "STRUCTURE_3nva", creates the "~~Structure ~~Box" on~~ the ~~page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_3nva\| PDB=3nva \| SCENE= }}~~	+

-	~~===Dimeric form~~ of ~~CTP synthase from Sulfolobus solfataricus===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_21301086}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 21301086 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_21301086}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3nva]] is a 2 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVA OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:021301086<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: CTP synthase]]		[[Category: CTP synthase]]
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]

OCA at 08:07, 25 April 2012

2012-04-25T08:07:10Z

←Older revision		Revision as of 08:07, 25 April 2012
Line 11:		Line 11:
	===Dimeric form of CTP synthase from Sulfolobus solfataricus===		===Dimeric form of CTP synthase from Sulfolobus solfataricus===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21301086}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21301086 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21301086}}

	==About this Structure==		==About this Structure==
	[[3nva]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVA OCA].		[[3nva]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVA OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021301086</ref><references group="xtra"/>
	[[Category: CTP synthase]]		[[Category: CTP synthase]]
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]
Line 21:		Line 30:
	[[Category: Lauritsen, I.]]		[[Category: Lauritsen, I.]]
	[[Category: Willemoes, M.]]		[[Category: Willemoes, M.]]
		+	[[Category: Ctp synthase activity]]
		+	[[Category: Ligase]]
		+	[[Category: Nucleotide binding]]
		+	[[Category: Rossman fold]]

OCA: Protected "3nva" [edit=sysop:move=sysop]

2011-02-09T05:31:58Z

Protected "3nva" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:31, 9 February 2011

OCA at 05:31, 9 February 2011

2011-02-09T05:31:57Z

←Older revision		Revision as of 05:31, 9 February 2011
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3nva.png\|left\|200px]]
-	[[Image:3nva.~~jpg~~\|left\|200px]]	+

	<!--		<!--
Line 14:		Line 13:

	==About this Structure==		==About this Structure==
-	~~3NVA~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVA OCA].	+	[[3nva]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVA OCA].
	[[Category: CTP synthase]]		[[Category: CTP synthase]]
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]
Line 22:		Line 21:
	[[Category: Lauritsen, I.]]		[[Category: Lauritsen, I.]]
	[[Category: Willemoes, M.]]		[[Category: Willemoes, M.]]
-	[[Category: Ctp synthase activity]]
-	[[Category: Ligase]]
-	[[Category: Nucleotide binding]]
-	[[Category: Rossman fold]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Sep 10 14:01:37 2010''