3ooa - Revision history

OCA at 11:17, 21 February 2024

2024-02-21T11:17:52Z

←Older revision		Revision as of 11:17, 21 February 2024
Line 3:		Line 3:
	<StructureSection load='3ooa' size='340' side='right'caption='[[3ooa]], [[Resolution\|resolution]] 2.04Å' scene=''>		<StructureSection load='3ooa' size='340' side='right'caption='[[3ooa]], [[Resolution\|resolution]] 2.04Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ooa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Acts5 Acts5~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OOA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OOA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ooa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Actinoplanes_sp._SE50/110 Actinoplanes sp. SE50/110]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OOA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OOA FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.04Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[3oo6\|3oo6]], [[3oo7\|3oo7]], [[3oo8\|3oo8]], [[3oo9\|3oo9]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">AcbH ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=134676 ACTS5])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ooa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ooa OCA], [https://pdbe.org/3ooa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ooa RCSB], [https://www.ebi.ac.uk/pdbsum/3ooa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ooa ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ooa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ooa OCA], [https://pdbe.org/3ooa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ooa RCSB], [https://www.ebi.ac.uk/pdbsum/3ooa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ooa ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/Q27GR2_ACTS5 Q27GR2_ACTS5]
-	Solute receptors (binding proteins) are indispensable components of canonical ATP-binding cassette importers in prokaryotes. Here, we report on the characterization and crystal structures in the closed and open conformations of AcbH, the solute receptor of the putative carbohydrate transporter AcbFG which is encoded in the acarbose (acarviosyl-1,4-maltose) biosynthetic gene cluster from Actinoplanes sp. SE50/110. Binding assays identified AcbH as a high-affinity monosaccharide-binding protein with a dissociation constant (K(d)) for beta-d-galactopyranose of 9.8+/-1.0 nM. Neither galactose-containing di- and trisaccharides, such as lactose and raffinose, nor monosaccharides including d-galacturonic acid, l-arabinose, d-xylose and l-rhamnose competed with [(1)(4)C]galactose for binding to AcbH. Moreover, AcbH does not bind d-glucose, which is a common property of all but one d-galactose-binding proteins characterized to date. Strikingly, determination of the X-ray structure revealed that AcbH is structurally homologous to maltose-binding proteins rather than to glucose-binding proteins. Two helices are inserted in the substrate-binding pocket, which reduces the cavity size and allows the exclusive binding of monosaccharides, specifically beta-d-galactopyranose, in the (4)C(1) conformation. Site-directed mutagenesis of three residues from the binding pocket (Arg82, Asp361 and Arg362) that interact with the axially oriented O4-H hydroxyl of the bound galactopyranose and subsequent functional analysis indicated that these residues are crucial for galactose binding. To our knowledge, this is the first report of the tertiary structure of a solute receptor with exclusive affinity for beta-d-galactopyranose. The putative role of a galactose import system in the context of acarbose metabolism in Actinoplanes sp. is discussed.	+
-		+
-	Crystal structures of the bacterial solute receptor AcbH displaying an exclusive substrate preference for beta-D-galactopyranose.,Licht A, Bulut H, Scheffel F, Daumke O, Wehmeier UF, Saenger W, Schneider E, Vahedi-Faridi A J Mol Biol. 2011 Feb 11;406(1):92-105. Epub 2010 Dec 17. PMID:21168419<ref>PMID:~~21168419<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®~~/~~PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 3ooa" style="background-color:#fffaf0;"><~~/~~div>~~	+
-	~~== References ==~~	+
-	~~<references/>~~	+
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Acts5~~]]	+	[[Category: Actinoplanes sp. SE50/110]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bulut, H]]	+	[[Category: Bulut H]]
-	[[Category: Licht, A]]	+	[[Category: Licht A]]
-	[[Category: Vahedi-Faridi, A]]	+	[[Category: Vahedi-Faridi A]]
-	~~[[Category: Abc transporter extracellular solute binding protein]]~~	+
-	~~[[Category: Class 2 sbp fold]]~~	+
-	~~[[Category: D-galactose binding]]~~	+
-	~~[[Category: Sugar binding protein~~]]	+

OCA at 10:51, 18 May 2022

2022-05-18T10:51:04Z

←Older revision		Revision as of 10:51, 18 May 2022
Line 1:		Line 1:

	==Crystal structures and biochemical characterization of the bacterial solute receptor AcbH reveal an unprecedented exclusive substrate preference for b-D-galactopyranose==		==Crystal structures and biochemical characterization of the bacterial solute receptor AcbH reveal an unprecedented exclusive substrate preference for b-D-galactopyranose==
-	<StructureSection load='3ooa' size='340' side='right' caption='[[3ooa]], [[Resolution\|resolution]] 2.04Å' scene=''>	+	<StructureSection load='3ooa' size='340' side='right'caption='[[3ooa]], [[Resolution\|resolution]] 2.04Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ooa]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Acts5 Acts5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OOA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3OOA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ooa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Acts5 Acts5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OOA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OOA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3oo6\|3oo6]], [[3oo7\|3oo7]], [[3oo8\|3oo8]], [[3oo9\|3oo9]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3oo6\|3oo6]], [[3oo7\|3oo7]], [[3oo8\|3oo8]], [[3oo9\|3oo9]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AcbH ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=134676 ACTS5])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AcbH ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=134676 ACTS5])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ooa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ooa OCA], [~~http~~://pdbe.org/3ooa PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3ooa RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3ooa PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3ooa ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ooa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ooa OCA], [https://pdbe.org/3ooa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ooa RCSB], [https://www.ebi.ac.uk/pdbsum/3ooa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ooa ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</StructureSection>		</StructureSection>
	[[Category: Acts5]]		[[Category: Acts5]]
		+	[[Category: Large Structures]]
	[[Category: Bulut, H]]		[[Category: Bulut, H]]
	[[Category: Licht, A]]		[[Category: Licht, A]]

OCA at 12:00, 4 August 2016

2016-08-04T12:00:13Z

←Older revision		Revision as of 12:00, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structures and biochemical characterization of the bacterial solute receptor AcbH reveal an unprecedented exclusive substrate preference for b-D-galactopyranose==		==Crystal structures and biochemical characterization of the bacterial solute receptor AcbH reveal an unprecedented exclusive substrate preference for b-D-galactopyranose==
	<StructureSection load='3ooa' size='340' side='right' caption='[[3ooa]], [[Resolution\|resolution]] 2.04Å' scene=''>		<StructureSection load='3ooa' size='340' side='right' caption='[[3ooa]], [[Resolution\|resolution]] 2.04Å' scene=''>
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3oo6\|3oo6]], [[3oo7\|3oo7]], [[3oo8\|3oo8]], [[3oo9\|3oo9]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3oo6\|3oo6]], [[3oo7\|3oo7]], [[3oo8\|3oo8]], [[3oo9\|3oo9]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AcbH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=134676 ACTS5])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AcbH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=134676 ACTS5])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ooa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ooa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ooa RCSB], [http://www.ebi.ac.uk/pdbsum/3ooa PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ooa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ooa OCA], [http://pdbe.org/3ooa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ooa RCSB], [http://www.ebi.ac.uk/pdbsum/3ooa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ooa ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3ooa" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 23:24, 3 January 2015

2015-01-03T23:24:02Z

←Older revision		Revision as of 23:24, 3 January 2015
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-	~~{{STRUCTURE_3ooa\| PDB=3ooa \| SCENE= }}~~	+	==Crystal structures and biochemical characterization of the bacterial solute receptor AcbH reveal an unprecedented exclusive substrate preference for b-D-galactopyranose==
-	===Crystal structures and biochemical characterization of the bacterial solute receptor AcbH reveal an unprecedented exclusive substrate preference for b-D-galactopyranose===	+	<StructureSection load='3ooa' size='340' side='right' caption='[[3ooa]], [[Resolution\|resolution]] 2.04Å' scene=''>
-	~~{{ABSTRACT_PUBMED_21168419}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3ooa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Acts5 Acts5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OOA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OOA FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3oo6\|3oo6]], [[3oo7\|3oo7]], [[3oo8\|3oo8]], [[3oo9\|3oo9]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AcbH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=134676 ACTS5])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ooa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ooa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ooa RCSB], [http://www.ebi.ac.uk/pdbsum/3ooa PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Solute receptors (binding proteins) are indispensable components of canonical ATP-binding cassette importers in prokaryotes. Here, we report on the characterization and crystal structures in the closed and open conformations of AcbH, the solute receptor of the putative carbohydrate transporter AcbFG which is encoded in the acarbose (acarviosyl-1,4-maltose) biosynthetic gene cluster from Actinoplanes sp. SE50/110. Binding assays identified AcbH as a high-affinity monosaccharide-binding protein with a dissociation constant (K(d)) for beta-d-galactopyranose of 9.8+/-1.0 nM. Neither galactose-containing di- and trisaccharides, such as lactose and raffinose, nor monosaccharides including d-galacturonic acid, l-arabinose, d-xylose and l-rhamnose competed with [(1)(4)C]galactose for binding to AcbH. Moreover, AcbH does not bind d-glucose, which is a common property of all but one d-galactose-binding proteins characterized to date. Strikingly, determination of the X-ray structure revealed that AcbH is structurally homologous to maltose-binding proteins rather than to glucose-binding proteins. Two helices are inserted in the substrate-binding pocket, which reduces the cavity size and allows the exclusive binding of monosaccharides, specifically beta-d-galactopyranose, in the (4)C(1) conformation. Site-directed mutagenesis of three residues from the binding pocket (Arg82, Asp361 and Arg362) that interact with the axially oriented O4-H hydroxyl of the bound galactopyranose and subsequent functional analysis indicated that these residues are crucial for galactose binding. To our knowledge, this is the first report of the tertiary structure of a solute receptor with exclusive affinity for beta-d-galactopyranose. The putative role of a galactose import system in the context of acarbose metabolism in Actinoplanes sp. is discussed.

-	~~==About this Structure==~~	+	Crystal structures of the bacterial solute receptor AcbH displaying an exclusive substrate preference for beta-D-galactopyranose.,Licht A, Bulut H, Scheffel F, Daumke O, Wehmeier UF, Saenger W, Schneider E, Vahedi-Faridi A J Mol Biol. 2011 Feb 11;406(1):92-105. Epub 2010 Dec 17. PMID:21168419<ref>PMID:21168419</ref>
-	~~[[3ooa]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Acts5 Acts5]. Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=3OOA OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:021168419</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Acts5]]		[[Category: Acts5]]
-	[[Category: Bulut, H.]]	+	[[Category: Bulut, H]]
-	[[Category: Licht, A.]]	+	[[Category: Licht, A]]
-	[[Category: Vahedi-Faridi, A.]]	+	[[Category: Vahedi-Faridi, A]]
	[[Category: Abc transporter extracellular solute binding protein]]		[[Category: Abc transporter extracellular solute binding protein]]
	[[Category: Class 2 sbp fold]]		[[Category: Class 2 sbp fold]]
	[[Category: D-galactose binding]]		[[Category: D-galactose binding]]
	[[Category: Sugar binding protein]]		[[Category: Sugar binding protein]]

OCA at 08:04, 26 March 2014

2014-03-26T08:04:52Z

←Older revision		Revision as of 08:04, 26 March 2014
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	{{STRUCTURE_3ooa\| PDB=3ooa \| SCENE= }}		{{STRUCTURE_3ooa\| PDB=3ooa \| SCENE= }}
	===Crystal structures and biochemical characterization of the bacterial solute receptor AcbH reveal an unprecedented exclusive substrate preference for b-D-galactopyranose===		===Crystal structures and biochemical characterization of the bacterial solute receptor AcbH reveal an unprecedented exclusive substrate preference for b-D-galactopyranose===
-	{{~~ABSTRACT_PUBMED_021168419~~}}	+	{{ABSTRACT_PUBMED_21168419}}

	==About this Structure==		==About this Structure==
-	[[3ooa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Actinoplanes Actinoplanes~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OOA OCA].	+	[[3ooa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Acts5 Acts5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OOA OCA].
-	[[Category: ~~Actinoplanes~~]]	+
		+	==Reference==
		+	<ref group="xtra">PMID:021168419</ref><references group="xtra"/><references/>
		+	[[Category: Acts5]]
	[[Category: Bulut, H.]]		[[Category: Bulut, H.]]
	[[Category: Licht, A.]]		[[Category: Licht, A.]]

OCA at 08:38, 2 May 2013

2013-05-02T08:38:04Z

←Older revision		Revision as of 08:38, 2 May 2013
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-	[[Image:3ooa.jpg\|left\|200px]]
-
-	<!--
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	{{STRUCTURE_3ooa\| PDB=3ooa \| SCENE= }}		{{STRUCTURE_3ooa\| PDB=3ooa \| SCENE= }}
-
	===Crystal structures and biochemical characterization of the bacterial solute receptor AcbH reveal an unprecedented exclusive substrate preference for b-D-galactopyranose===		===Crystal structures and biochemical characterization of the bacterial solute receptor AcbH reveal an unprecedented exclusive substrate preference for b-D-galactopyranose===
-		+	{{ABSTRACT_PUBMED_021168419}}

	==About this Structure==		==About this Structure==

OCA: Protected "3ooa" [edit=sysop:move=sysop]

2010-12-29T18:38:21Z

Protected "3ooa" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:38, 29 December 2010

OCA at 18:38, 29 December 2010

2010-12-29T18:38:19Z

←Older revision		Revision as of 18:38, 29 December 2010
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-	~~'''Unreleased structure'''~~	+	[[Image:3ooa.jpg\|left\|200px]]

-	The ~~entry 3ooa~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3ooa", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3ooa\| PDB=3ooa \| SCENE= }}

-	~~Authors: Vahedi~~-~~Faridi, A., Bulut, H., Licht, A.~~	+	===Crystal structures and biochemical characterization of the bacterial solute receptor AcbH reveal an unprecedented exclusive substrate preference for b-D-galactopyranose===

-	Description: Crystal structures and biochemical characterization of the bacterial solute receptor AcbH reveal an unprecedented exclusive substrate preference for b-D-galactopyranose

-	~~''Page seeded by~~ [http://oca.weizmann.ac.il/oca OCA ] ~~on Wed Sep 29 07~~:56:~~43 2010''~~	+	==About this Structure==
		+	[[3ooa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Actinoplanes Actinoplanes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OOA OCA].
		+	[[Category: Actinoplanes]]
		+	[[Category: Bulut, H.]]
		+	[[Category: Licht, A.]]
		+	[[Category: Vahedi-Faridi, A.]]
		+	[[Category: Abc transporter extracellular solute binding protein]]
		+	[[Category: Class 2 sbp fold]]
		+	[[Category: D-galactose binding]]
		+	[[Category: Sugar binding protein]]

OCA at 04:47, 29 September 2010

2010-09-29T04:47:28Z

←Older revision		Revision as of 04:47, 29 September 2010
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3ooa is ON HOLD	+	The entry 3ooa is ON HOLD until Paper Publication

	Authors: Vahedi-Faridi, A., Bulut, H., Licht, A.		Authors: Vahedi-Faridi, A., Bulut, H., Licht, A.
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	Description: Crystal structures and biochemical characterization of the bacterial solute receptor AcbH reveal an unprecedented exclusive substrate preference for b-D-galactopyranose		Description: Crystal structures and biochemical characterization of the bacterial solute receptor AcbH reveal an unprecedented exclusive substrate preference for b-D-galactopyranose

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep ~~15 10~~:38:00 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 29 07:56:43 2010''

OCA: New page: '''Unreleased structure''' The entry 3ooa is ON HOLD Authors: Vahedi-Faridi, A., Bulut, H., Licht, A. Description: Crystal structures and biochemical characterization of the bacterial ...

2010-09-15T07:29:17Z

New page: '''Unreleased structure''' The entry 3ooa is ON HOLD Authors: Vahedi-Faridi, A., Bulut, H., Licht, A. Description: Crystal structures and biochemical characterization of the bacterial ...

New page

'''Unreleased structure'''

The entry 3ooa is ON HOLD

Authors: Vahedi-Faridi, A., Bulut, H., Licht, A.

Description: Crystal structures and biochemical characterization of the bacterial solute receptor AcbH reveal an unprecedented exclusive substrate preference for b-D-galactopyranose

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 15 10:38:00 2010''