3pm6 - Revision history

OCA at 09:56, 6 September 2023

2023-09-06T09:56:52Z

←Older revision		Revision as of 09:56, 6 September 2023
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	<StructureSection load='3pm6' size='340' side='right'caption='[[3pm6]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='3pm6' size='340' side='right'caption='[[3pm6]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3pm6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Cbs_120936 Cbs 120936~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PM6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PM6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3pm6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Coccidioides_immitis Coccidioides immitis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PM6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PM6 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>~~, ~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>CIMG_05755 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~5501 CBS 120936])</td~~><~~/tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Fructose-bisphosphate_aldolase Fructose-bisphosphate aldolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.13 4.1.2.13]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pm6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pm6 OCA], [https://pdbe.org/3pm6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pm6 RCSB], [https://www.ebi.ac.uk/pdbsum/3pm6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pm6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pm6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pm6 OCA], [https://pdbe.org/3pm6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pm6 RCSB], [https://www.ebi.ac.uk/pdbsum/3pm6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pm6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/ALF_COCIM ALF_COCIM]] Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (By similarity).	+	[https://www.uniprot.org/uniprot/ALF_COCIM ALF_COCIM] Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Cbs 120936]]~~	+	[[Category: Coccidioides immitis]]
-	~~[[Category: Fructose-bisphosphate aldolase~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Structural genomic]]
-	[[Category: 6-bisphosphate aldolase]]
-	[[Category: Coccidioide]]
-	[[Category: Coccidioidomycosis]]
-	[[Category: Fructose-1]]
-	[[Category: Immitis]]
-	[[Category: Lyase]]
-	[[Category: Pathogenic fungus]]
-	[[Category: Posadasii]]
-	[[Category: Ssgcid]]
-	[[Category: Valley fever]]
-	[[Category: Zinc-containing enzyme]]

OCA at 08:45, 25 May 2022

2022-05-25T08:45:24Z

←Older revision		Revision as of 08:45, 25 May 2022
Line 1:		Line 1:

	==Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR==		==Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR==
-	<StructureSection load='3pm6' size='340' side='right' caption='[[3pm6]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='3pm6' size='340' side='right'caption='[[3pm6]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3pm6]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Cocit Cocit~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PM6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3PM6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3pm6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cbs_120936 Cbs 120936]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PM6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PM6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CIMG_05755 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5501 ~~COCIT~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CIMG_05755 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5501 CBS 120936])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Fructose-bisphosphate_aldolase Fructose-bisphosphate aldolase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.13 4.1.2.13] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Fructose-bisphosphate_aldolase Fructose-bisphosphate aldolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.13 4.1.2.13] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3pm6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pm6 OCA], [~~http~~://pdbe.org/3pm6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3pm6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3pm6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3pm6 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pm6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pm6 OCA], [https://pdbe.org/3pm6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pm6 RCSB], [https://www.ebi.ac.uk/pdbsum/3pm6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pm6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/ALF_COCIM ALF_COCIM]] Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (By similarity).	+	[[https://www.uniprot.org/uniprot/ALF_COCIM ALF_COCIM]] Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Cocit~~]]	+	[[Category: Cbs 120936]]
	[[Category: Fructose-bisphosphate aldolase]]		[[Category: Fructose-bisphosphate aldolase]]
		+	[[Category: Large Structures]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: 6-bisphosphate aldolase]]		[[Category: 6-bisphosphate aldolase]]

OCA at 20:50, 4 August 2016

2016-08-04T20:50:37Z

←Older revision		Revision as of 20:50, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR==		==Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR==
	<StructureSection load='3pm6' size='340' side='right' caption='[[3pm6]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='3pm6' size='340' side='right' caption='[[3pm6]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3pm6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Coccidioides_immitis Coccidioides immitis~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PM6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PM6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3pm6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cocit Cocit]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PM6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PM6 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CIMG_05755 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5501 ~~Coccidioides immitis~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CIMG_05755 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5501 COCIT])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphate_aldolase Fructose-bisphosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.13 4.1.2.13] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphate_aldolase Fructose-bisphosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.13 4.1.2.13] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pm6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pm6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pm6 RCSB], [http://www.ebi.ac.uk/pdbsum/3pm6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pm6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pm6 OCA], [http://pdbe.org/3pm6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3pm6 RCSB], [http://www.ebi.ac.uk/pdbsum/3pm6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3pm6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3pm6" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Coccidioides immitis~~]]	+	[[Category: Cocit]]
	[[Category: Fructose-bisphosphate aldolase]]		[[Category: Fructose-bisphosphate aldolase]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA at 19:31, 24 December 2014

2014-12-24T19:31:57Z

←Older revision		Revision as of 19:31, 24 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pm6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pm6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pm6 RCSB], [http://www.ebi.ac.uk/pdbsum/3pm6 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pm6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pm6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pm6 RCSB], [http://www.ebi.ac.uk/pdbsum/3pm6 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ALF_COCIM ALF_COCIM]] Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 10:56, 19 December 2014

2014-12-19T10:56:16Z

←Older revision		Revision as of 10:56, 19 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3pm6\| PDB=3pm6 \| SCENE= }}~~	+	==Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR==
-	===Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR===	+	<StructureSection load='3pm6' size='340' side='right' caption='[[3pm6]], [[Resolution\|resolution]] 2.20Å' scene=''>
-	~~{{ABSTRACT_PUBMED_21359836}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3pm6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Coccidioides_immitis Coccidioides immitis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PM6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PM6 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CIMG_05755 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5501 Coccidioides immitis])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphate_aldolase Fructose-bisphosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.13 4.1.2.13] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pm6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pm6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pm6 RCSB], [http://www.ebi.ac.uk/pdbsum/3pm6 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Seattle Structural Genomics Center for Infectious Disease (SSGCID) focuses on the structure elucidation of potential drug targets from class A, B, and C infectious disease organisms. Many SSGCID targets are selected because they have homologs in other organisms that are validated drug targets with known structures. Thus, many SSGCID targets are expected to be solved by molecular replacement (MR), and reflective of this, all proteins are expressed in native form. However, many community request targets do not have homologs with known structures and not all internally selected targets readily solve by MR, necessitating experimental phase determination. We have adopted the use of iodide ion soaks and single wavelength anomalous dispersion (SAD) experiments as our primary method for de novo phasing. This method uses existing native crystals and in house data collection, resulting in rapid, low cost structure determination. Iodide ions are non-toxic and soluble at molar concentrations, facilitating binding at numerous hydrophobic or positively charged sites. We have used this technique across a wide range of crystallization conditions with successful structure determination in 16 of 17 cases within the first year of use (94% success rate). Here we present a general overview of this method as well as several examples including SAD phasing of proteins with novel folds and the combined use of SAD and MR for targets with weak MR solutions. These cases highlight the straightforward and powerful method of iodide ion SAD phasing in a high-throughput structural genomics environment.

-	~~==Function==~~	+	SAD phasing using iodide ions in a high-throughput structural genomics environment.,Abendroth J, Gardberg AS, Robinson JI, Christensen JS, Staker BL, Myler PJ, Stewart LJ, Edwards TE J Struct Funct Genomics. 2011 Jul;12(2):83-95. Epub 2011 Feb 27. PMID:21359836<ref>PMID:21359836</ref>
-	~~[[http://www~~.~~uniprot~~.~~org/uniprot/ALF_COCIM ALF_COCIM]] Catalyzes the aldol condensation of dihydroxyacetone phosphate~~ (~~DHAP or glycerone-phosphate~~) ~~with glyceraldehyde 3~~-~~phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (By similarity)~~.	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[3pm6]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Coccidioides_immitis Coccidioides immitis]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3PM6 OCA].~~	+	</div>
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:021359836</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Coccidioides immitis]]		[[Category: Coccidioides immitis]]
	[[Category: Fructose-bisphosphate aldolase]]		[[Category: Fructose-bisphosphate aldolase]]
-	[[Category: ~~SSGCID, Seattle~~ Structural ~~Genomics Center for Infectious Disease.~~]]	+	[[Category: Structural genomic]]
	[[Category: 6-bisphosphate aldolase]]		[[Category: 6-bisphosphate aldolase]]
	[[Category: Coccidioide]]		[[Category: Coccidioide]]
Line 22:		Line 31:
	[[Category: Pathogenic fungus]]		[[Category: Pathogenic fungus]]
	[[Category: Posadasii]]		[[Category: Posadasii]]
-	[[Category: Seattle structural genomics center for infectious disease]]
	[[Category: Ssgcid]]		[[Category: Ssgcid]]
-	[[Category: Structural genomic]]
	[[Category: Valley fever]]		[[Category: Valley fever]]
	[[Category: Zinc-containing enzyme]]		[[Category: Zinc-containing enzyme]]

OCA at 08:22, 8 May 2013

2013-05-08T08:22:12Z

←Older revision		Revision as of 08:22, 8 May 2013
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-	[[Image:3pm6.png\|left\|200px]]
-
-	<!--
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-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3pm6\| PDB=3pm6 \| SCENE= }}		{{STRUCTURE_3pm6\| PDB=3pm6 \| SCENE= }}
-
	===Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR===		===Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR===
		+	{{ABSTRACT_PUBMED_21359836}}

-		+	==Function==
-	~~<!--~~	+	[[http://www.uniprot.org/uniprot/ALF_COCIM ALF_COCIM]] Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (By similarity).
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_21359836}}, adds the Publication Abstract to the page~~	+
-	~~(as it appears on PubMed at~~ http://www.~~pubmed~~.~~gov~~), ~~where 21359836 is~~ the ~~PubMed ID number~~.	+
-	~~-->~~	+
-	~~{{ABSTRACT_PUBMED_21359836}}~~	+

	==About this Structure==		==About this Structure==
Line 22:		Line 10:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:021359836</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021359836</ref><references group="xtra"/><references/>
	[[Category: Coccidioides immitis]]		[[Category: Coccidioides immitis]]
	[[Category: Fructose-bisphosphate aldolase]]		[[Category: Fructose-bisphosphate aldolase]]

OCA at 17:52, 6 July 2011

2011-07-06T17:52:01Z

←Older revision		Revision as of 17:52, 6 July 2011
Line 11:		Line 11:
	===Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR===		===Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21359836}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21359836 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21359836}}

	==About this Structure==		==About this Structure==
	[[3pm6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Coccidioides_immitis Coccidioides immitis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PM6 OCA].		[[3pm6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Coccidioides_immitis Coccidioides immitis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PM6 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021359836</ref><references group="xtra"/>
	[[Category: Coccidioides immitis]]		[[Category: Coccidioides immitis]]
	[[Category: Fructose-bisphosphate aldolase]]		[[Category: Fructose-bisphosphate aldolase]]
	[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]		[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]
		+	[[Category: 6-bisphosphate aldolase]]
		+	[[Category: Coccidioide]]
		+	[[Category: Coccidioidomycosis]]
		+	[[Category: Fructose-1]]
		+	[[Category: Immitis]]
		+	[[Category: Lyase]]
		+	[[Category: Pathogenic fungus]]
		+	[[Category: Posadasii]]
		+	[[Category: Seattle structural genomics center for infectious disease]]
		+	[[Category: Ssgcid]]
		+	[[Category: Structural genomic]]
		+	[[Category: Valley fever]]
		+	[[Category: Zinc-containing enzyme]]

OCA: Protected "3pm6" [edit=sysop:move=sysop]

2011-02-02T05:50:58Z

Protected "3pm6" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:50, 2 February 2011

OCA at 05:50, 2 February 2011

2011-02-02T05:50:57Z

←Older revision		Revision as of 05:50, 2 February 2011
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3pm6.png\|left\|200px]]
-	[[Image:3pm6.~~jpg~~\|left\|200px]]	+

	<!--		<!--
Line 14:		Line 13:

	==About this Structure==		==About this Structure==
-	~~3PM6~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Coccidioides_immitis Coccidioides immitis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PM6 OCA].	+	[[3pm6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Coccidioides_immitis Coccidioides immitis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PM6 OCA].
	[[Category: Coccidioides immitis]]		[[Category: Coccidioides immitis]]
		+	[[Category: Fructose-bisphosphate aldolase]]
	[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]		[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]
-	[[Category: 6-bisphosphate aldolase]]
-	[[Category: Coccidioide]]
-	[[Category: Coccidioidomycosis]]
-	[[Category: Fructose-1]]
-	[[Category: Immitis]]
-	[[Category: Lyase]]
-	[[Category: Pathogenic fungus]]
-	[[Category: Posadasii]]
-	[[Category: Seattle structural genomics center for infectious disease]]
-	[[Category: Ssgcid]]
-	[[Category: Structural genomic]]
-	[[Category: Valley fever]]
-	[[Category: Zinc-containing enzyme]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:44:58 2010''

OCA at 05:32, 15 December 2010

2010-12-15T05:32:38Z

←Older revision		Revision as of 05:32, 15 December 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3pm6.jpg\|left\|200px]]

-	The ~~entry 3pm6~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3pm6", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3pm6\| PDB=3pm6 \| SCENE= }}

-	~~Authors: Edwards~~, ~~T.E., Gardberg, A.S., Seattle Structural Genomics Center for Infectious Disease (SSGCID)~~	+	===Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR===

-	Description: Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Nov 24 13~~:58:51 2010''	+	==About this Structure==
		+	3PM6 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Coccidioides_immitis Coccidioides immitis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PM6 OCA].
		+	[[Category: Coccidioides immitis]]
		+	[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]
		+	[[Category: 6-bisphosphate aldolase]]
		+	[[Category: Coccidioide]]
		+	[[Category: Coccidioidomycosis]]
		+	[[Category: Fructose-1]]
		+	[[Category: Immitis]]
		+	[[Category: Lyase]]
		+	[[Category: Pathogenic fungus]]
		+	[[Category: Posadasii]]
		+	[[Category: Seattle structural genomics center for infectious disease]]
		+	[[Category: Ssgcid]]
		+	[[Category: Structural genomic]]
		+	[[Category: Valley fever]]
		+	[[Category: Zinc-containing enzyme]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:44:58 2010''