3pma - Revision history

OCA at 09:56, 6 September 2023

2023-09-06T09:56:56Z

←Older revision		Revision as of 09:56, 6 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3pma]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PMA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PMA FirstGlance]. <br>		<table><tr><td colspan='2'>[[3pma]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PMA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PMA FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>~~, ~~<scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=GU4:~~2~~,3,4,6-TETRA-O-SULFONATO-ALPHA-D-GLUCOPYRANOSE'>GU4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~YYJ~~:'>~~YYJ~~</scene><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GU4:2,3,4,6-TETRA-O-SULFONATO-ALPHA-D-GLUCOPYRANOSE'>GU4</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PRD_900013:sucrose+octasulfate'>PRD_900013</scene>, <scene name='pdbligand=YYJ:1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose'>YYJ</scene></td></tr>
-	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b~~></td><~~td class~~=~~"sblockDat"><div style~~=~~'overflow~~: ~~auto; max-height: 3em;~~'>~~[[3pmb\|3pmb]]~~</~~div~~><~~/td></tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks'>[https~~:~~//en.wikipedia.org/wiki/Thrombin Thrombin]~~, ~~with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=~~3.4~~.21.5 3.4.21.5]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pma OCA], [https://pdbe.org/3pma PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pma RCSB], [https://www.ebi.ac.uk/pdbsum/3pma PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pma ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pma OCA], [https://pdbe.org/3pma PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pma RCSB], [https://www.ebi.ac.uk/pdbsum/3pma PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pma ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/THRB_BOVIN THRB_BOVIN]] Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	+	[https://www.uniprot.org/uniprot/THRB_BOVIN THRB_BOVIN] Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 30:		Line 28:
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Thrombin]]~~	+	[[Category: Desai BJ]]
-	[[Category: Desai~~, B J~~]]	+	[[Category: Scarsdale JN]]
-	[[Category: Scarsdale~~, J N~~]]	+	[[Category: Wright HT]]
-	[[Category: Wright~~, H T]]~~	+
-	~~[[Category: Agonist]]~~	+
-	~~[[Category: Fibrinolysis]]~~	+
-	~~[[Category: Hydrolase-hydrolase inhibitor complex]]~~	+
-	~~[[Category: Protease]]~~	+
-	~~[[Category: Thrombosis~~]]	+

OCA at 08:45, 25 May 2022

2022-05-25T08:45:33Z

←Older revision		Revision as of 08:45, 25 May 2022
Line 1:		Line 1:

	==2.2 Angstrom crystal structure of the complex between Bovine Thrombin and Sucrose Octasulfate==		==2.2 Angstrom crystal structure of the complex between Bovine Thrombin and Sucrose Octasulfate==
-	<StructureSection load='3pma' size='340' side='right' caption='[[3pma]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='3pma' size='340' side='right'caption='[[3pma]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3pma]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PMA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3PMA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3pma]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PMA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PMA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=~~SCR~~:~~SUCROSE+OCTASULFATE~~'>~~SCR~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=GU4:2,3,4,6-TETRA-O-SULFONATO-ALPHA-D-GLUCOPYRANOSE'>GU4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3pmb\|3pmb]]</td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=YYJ:'>YYJ</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] </span></td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3pmb\|3pmb]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3pma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pma OCA], [~~http~~://pdbe.org/3pma PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3pma RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3pma PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3pma ProSAT]</span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pma OCA], [https://pdbe.org/3pma PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pma RCSB], [https://www.ebi.ac.uk/pdbsum/3pma PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pma ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/THRB_BOVIN THRB_BOVIN]] Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	+	[[https://www.uniprot.org/uniprot/THRB_BOVIN THRB_BOVIN]] Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 23:

	==See Also==		==See Also==
-	*[[Thrombin\|Thrombin]]	+	*[[Thrombin 3D Structures\|Thrombin 3D Structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 28:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
		+	[[Category: Large Structures]]
	[[Category: Thrombin]]		[[Category: Thrombin]]
	[[Category: Desai, B J]]		[[Category: Desai, B J]]

OCA at 14:16, 5 August 2016

2016-08-05T14:16:43Z

←Older revision		Revision as of 14:16, 5 August 2016
Line 1:		Line 1:
		+
	==2.2 Angstrom crystal structure of the complex between Bovine Thrombin and Sucrose Octasulfate==		==2.2 Angstrom crystal structure of the complex between Bovine Thrombin and Sucrose Octasulfate==
	<StructureSection load='3pma' size='340' side='right' caption='[[3pma]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='3pma' size='340' side='right' caption='[[3pma]], [[Resolution\|resolution]] 2.20Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3pmb\|3pmb]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3pmb\|3pmb]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pma OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pma RCSB], [http://www.ebi.ac.uk/pdbsum/3pma PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pma OCA], [http://pdbe.org/3pma PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3pma RCSB], [http://www.ebi.ac.uk/pdbsum/3pma PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3pma ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3pma" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 19:30, 25 December 2014

2014-12-25T19:30:27Z

←Older revision		Revision as of 19:30, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pma OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pma RCSB], [http://www.ebi.ac.uk/pdbsum/3pma PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pma OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pma RCSB], [http://www.ebi.ac.uk/pdbsum/3pma PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/THRB_BOVIN THRB_BOVIN]] Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 12:22, 9 December 2014

2014-12-09T12:22:26Z

←Older revision		Revision as of 12:22, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3pma.~~png~~\|~~left~~\|~~200px~~]]	+	==2.2 Angstrom crystal structure of the complex between Bovine Thrombin and Sucrose Octasulfate==
		+	<StructureSection load='3pma' size='340' side='right' caption='[[3pma]], [[Resolution\|resolution]] 2.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3pma]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PMA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PMA FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SCR:SUCROSE+OCTASULFATE'>SCR</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3pmb\|3pmb]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pma OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pma RCSB], [http://www.ebi.ac.uk/pdbsum/3pma PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The serine protease thrombin plays multiple roles in many important physiological processes, especially coagulation, where it functions as both a pro- and anticoagulant. The polyanionic glycosaminoglycan heparin modulates thrombin's activity through binding at exosite II. Sucrose octasulfate (SOS) is often used as a surrogate for heparin, but it is not known whether it is an effective heparin mimic in its interaction with thrombin. We have characterized the interaction of SOS with thrombin in solution and determined a crystal structure of their complex. SOS binds thrombin with a K(d) of approximately 1.4 muM, comparable to that of the much larger polymeric heparin measured under the same conditions. Nonionic (hydrogen bonding) interactions make a larger contribution to thrombin binding of SOS than to heparin. SOS binding to exosite II inhibits thrombin's catalytic activity with high potency but with low efficacy. Analytical ultracentrifugation shows that bovine and human thrombins are monomers in solution in the presence of SOS, in contrast to their complexes with heparin, which are dimers. In the X-ray crystal structure, two molecules of SOS are bound nonequivalently to exosite II portions of a thrombin dimer, in contrast to the 1:2 stoichiometry of the heparin-thrombin complex, which has a different monomer association mode in the dimer. SOS and heparin binding to exosite II of thrombin differ on both chemical and structural levels and, perhaps most significantly, in thrombin inhibition. These differences may offer paths to the design of more potent exosite II binding, allosteric small molecules as modulators of thrombin function.

-	~~{{STRUCTURE_3pma\| PDB=3pma \| SCENE= }}~~	+	Interaction of Thrombin with Sucrose Octasulfate.,Desai BJ, Boothello RS, Mehta AY, Scarsdale JN, Wright HT, Desai UR Biochemistry. 2011 Jul 18. PMID:21736375<ref>PMID:21736375</ref>

-	~~===2.2 Angstrom crystal structure~~ of the ~~complex between Bovine Thrombin and Sucrose Octasulfate===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_21736375}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3pma]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bos_taurus Bos taurus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3PMA OCA].~~	+

	==See Also==		==See Also==
	*[[Thrombin\|Thrombin]]		*[[Thrombin\|Thrombin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:021736375<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Thrombin]]		[[Category: Thrombin]]
-	[[Category: Desai, B J.]]	+	[[Category: Desai, B J]]
-	[[Category: Scarsdale, J N.]]	+	[[Category: Scarsdale, J N]]
-	[[Category: Wright, H T.]]	+	[[Category: Wright, H T]]
	[[Category: Agonist]]		[[Category: Agonist]]
	[[Category: Fibrinolysis]]		[[Category: Fibrinolysis]]

OCA at 20:33, 20 October 2012

2012-10-20T20:33:41Z

←Older revision		Revision as of 20:33, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3pma]] is a 4 chain structure ~~of [[Thrombin]]~~ with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PMA OCA].	+	[[3pma]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PMA OCA].

	==See Also==		==See Also==

OCA at 10:54, 27 July 2012

2012-07-27T10:54:21Z

←Older revision		Revision as of 10:54, 27 July 2012
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	[[Image:3pma.png\|left\|200px]]		[[Image:3pma.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_3pma\| PDB=3pma \| SCENE= }}		{{STRUCTURE_3pma\| PDB=3pma \| SCENE= }}

	===2.2 Angstrom crystal structure of the complex between Bovine Thrombin and Sucrose Octasulfate===		===2.2 Angstrom crystal structure of the complex between Bovine Thrombin and Sucrose Octasulfate===

-
-	<!--
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	{{ABSTRACT_PUBMED_21736375}}		{{ABSTRACT_PUBMED_21736375}}

	==About this Structure==		==About this Structure==
-	[[3pma]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PMA OCA].	+	[[3pma]] is a 4 chain structure of [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PMA OCA].
		+
		+	==See Also==
		+	*[[Thrombin\|Thrombin]]

	==Reference==		==Reference==

OCA at 06:14, 27 July 2011

2011-07-27T06:14:10Z

←Older revision		Revision as of 06:14, 27 July 2011
Line 1:		Line 1:
-	[[Image:3pma.~~jpg~~\|left\|200px]]	+	[[Image:3pma.png\|left\|200px]]

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OCA: Protected "3pma" [edit=sysop:move=sysop]

2011-07-20T06:36:28Z

Protected "3pma" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:36, 20 July 2011

OCA at 06:36, 20 July 2011

2011-07-20T06:36:22Z

←Older revision		Revision as of 06:36, 20 July 2011
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-	~~'''Unreleased structure'''~~	+	[[Image:3pma.jpg\|left\|200px]]

-	The ~~entry 3pma~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3pma", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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		+	{{STRUCTURE_3pma\| PDB=3pma \| SCENE= }}

-	~~Authors: Wright, H.T., Scarsdale, J.N., Desai, B.J~~.	+	===2.2 Angstrom crystal structure of the complex between Bovine Thrombin and Sucrose Octasulfate===

-	Description: 2.2 Angstrom crystal structure of the complex between Bovine Thrombin and Sucrose Octasulfate

-	~~''Page seeded by~~ [http://oca.weizmann.ac.il/oca OCA ] ~~on Wed Dec 15 08~~:24:~~15 2010''~~	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21736375}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21736375 is the PubMed ID number.
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		+	{{ABSTRACT_PUBMED_21736375}}
		+
		+	==About this Structure==
		+	[[3pma]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PMA OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021736375</ref><references group="xtra"/>
		+	[[Category: Bos taurus]]
		+	[[Category: Thrombin]]
		+	[[Category: Desai, B J.]]
		+	[[Category: Scarsdale, J N.]]
		+	[[Category: Wright, H T.]]
		+	[[Category: Agonist]]
		+	[[Category: Fibrinolysis]]
		+	[[Category: Hydrolase-hydrolase inhibitor complex]]
		+	[[Category: Protease]]
		+	[[Category: Thrombosis]]