3pxh - Revision history

OCA at 13:34, 1 March 2024

2024-03-01T13:34:47Z

←Older revision		Revision as of 13:34, 1 March 2024
Line 3:		Line 3:
	<StructureSection load='3pxh' size='340' side='right'caption='[[3pxh]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3pxh' size='340' side='right'caption='[[3pxh]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3pxh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Lk3_transgenic_mice Lk3 transgenic mice~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PXH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PXH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3pxh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PXH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PXH FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.0009Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[3px5\|3px5]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>Ptprf, Lar ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~10090 LK3 transgenic mice])</td~~><~~/tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pxh OCA], [https://pdbe.org/3pxh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pxh RCSB], [https://www.ebi.ac.uk/pdbsum/3pxh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pxh ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pxh OCA], [https://pdbe.org/3pxh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pxh RCSB], [https://www.ebi.ac.uk/pdbsum/3pxh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pxh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/PTPRF_MOUSE PTPRF_MOUSE]] Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity (By similarity).	+	[https://www.uniprot.org/uniprot/PTPRF_MOUSE PTPRF_MOUSE] Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity (By similarity).
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	Neurogenesis depends on exquisitely regulated interactions between macromolecules on the cell surface and in the extracellular matrix. In particular, interactions between proteoglycans and members of the type IIa subgroup of receptor protein tyrosine phosphatases underlie crucial developmental processes such as the formation of synapses at the neuromuscular junction and the migration of axons to their appropriate targets. We report the crystal structures of the first and second immunoglobulin-like domains of the Drosophila type IIa receptor Dlar and its mouse homolog LAR. These two domains adopt an unusual antiparallel arrangement that has not been reported in tandem repeats of immunoglobulin-like domains and that is presumably conserved in all type IIa receptor protein tyrosine phosphatases.	+
-		+
-	The Immunoglobulin-like Domains 1 and 2 of the Protein Tyrosine Phosphatase LAR Adopt an Unusual Horseshoe-like Conformation.,Biersmith BH, Hammel M, Geisbrecht ER, Bouyain S J Mol Biol. 2011 May 13;408(4):616-27. Epub 2011 Mar 21. PMID:21402080<ref>PMID:21402080</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 3pxh" style="background-color:#fffaf0;"></div>~~	+

	==See Also==		==See Also==
	*[[Tyrosine phosphatase 3D structures\|Tyrosine phosphatase 3D structures]]		*[[Tyrosine phosphatase 3D structures\|Tyrosine phosphatase 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Lk3 transgenic mice]]~~	+	[[Category: Mus musculus]]
-	~~[[Category: Protein-tyrosine-phosphatase~~]]	+	[[Category: Biersmith BH]]
-	[[Category: Biersmith~~, B H~~]]	+	[[Category: Bouyain S]]
-	[[Category: Bouyain, S]]	+
-	~~[[Category: Cell adhesion]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Ig domain]]~~	+
-	~~[[Category: Receptor protein tyrosine phosphatase~~]]	+

OCA at 09:00, 25 May 2022

2022-05-25T09:00:29Z

←Older revision		Revision as of 09:00, 25 May 2022
Line 1:		Line 1:

	==Tandem Ig domains of tyrosine phosphatase LAR==		==Tandem Ig domains of tyrosine phosphatase LAR==
-	<StructureSection load='3pxh' size='340' side='right' caption='[[3pxh]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='3pxh' size='340' side='right'caption='[[3pxh]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3pxh]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PXH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3PXH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3pxh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PXH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PXH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3px5\|3px5]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3px5\|3px5]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ptprf, Lar ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ptprf, Lar ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3pxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pxh OCA], [~~http~~://pdbe.org/3pxh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3pxh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3pxh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3pxh ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pxh OCA], [https://pdbe.org/3pxh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pxh RCSB], [https://www.ebi.ac.uk/pdbsum/3pxh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pxh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/PTPRF_MOUSE PTPRF_MOUSE]] Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity (By similarity).	+	[[https://www.uniprot.org/uniprot/PTPRF_MOUSE PTPRF_MOUSE]] Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 21:
	</div>		</div>
	<div class="pdbe-citations 3pxh" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3pxh" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Tyrosine phosphatase 3D structures\|Tyrosine phosphatase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Lk3 transgenic mice]]		[[Category: Lk3 transgenic mice]]
	[[Category: Protein-tyrosine-phosphatase]]		[[Category: Protein-tyrosine-phosphatase]]

OCA at 09:08, 8 November 2017

2017-11-08T09:08:05Z

←Older revision		Revision as of 09:08, 8 November 2017
Line 21:		Line 21:
	</div>		</div>
	<div class="pdbe-citations 3pxh" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3pxh" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Tyrosine phosphatase\|Tyrosine phosphatase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 00:54, 5 August 2016

2016-08-05T00:54:38Z

←Older revision		Revision as of 00:54, 5 August 2016
Line 1:		Line 1:
		+
	==Tandem Ig domains of tyrosine phosphatase LAR==		==Tandem Ig domains of tyrosine phosphatase LAR==
	<StructureSection load='3pxh' size='340' side='right' caption='[[3pxh]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3pxh' size='340' side='right' caption='[[3pxh]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3pxh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PXH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PXH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3pxh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PXH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PXH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3px5\|3px5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3px5\|3px5]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ptprf, Lar ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 ~~Mus musculus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ptprf, Lar ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pxh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pxh RCSB], [http://www.ebi.ac.uk/pdbsum/3pxh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pxh OCA], [http://pdbe.org/3pxh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3pxh RCSB], [http://www.ebi.ac.uk/pdbsum/3pxh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3pxh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3pxh" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 26:		Line 28:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mus musculus~~]]	+	[[Category: Lk3 transgenic mice]]
	[[Category: Protein-tyrosine-phosphatase]]		[[Category: Protein-tyrosine-phosphatase]]
	[[Category: Biersmith, B H]]		[[Category: Biersmith, B H]]

OCA at 14:31, 25 December 2014

2014-12-25T14:31:25Z

←Older revision		Revision as of 14:31, 25 December 2014
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pxh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pxh RCSB], [http://www.ebi.ac.uk/pdbsum/3pxh PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pxh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pxh RCSB], [http://www.ebi.ac.uk/pdbsum/3pxh PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PTPRF_MOUSE PTPRF_MOUSE]] Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 12:02, 9 December 2014

2014-12-09T12:02:38Z

←Older revision		Revision as of 12:02, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3pxh.~~png~~\|~~left~~\|~~200px~~]]	+	==Tandem Ig domains of tyrosine phosphatase LAR==
		+	<StructureSection load='3pxh' size='340' side='right' caption='[[3pxh]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3pxh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PXH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PXH FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3px5\|3px5]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Ptprf, Lar ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pxh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pxh RCSB], [http://www.ebi.ac.uk/pdbsum/3pxh PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Neurogenesis depends on exquisitely regulated interactions between macromolecules on the cell surface and in the extracellular matrix. In particular, interactions between proteoglycans and members of the type IIa subgroup of receptor protein tyrosine phosphatases underlie crucial developmental processes such as the formation of synapses at the neuromuscular junction and the migration of axons to their appropriate targets. We report the crystal structures of the first and second immunoglobulin-like domains of the Drosophila type IIa receptor Dlar and its mouse homolog LAR. These two domains adopt an unusual antiparallel arrangement that has not been reported in tandem repeats of immunoglobulin-like domains and that is presumably conserved in all type IIa receptor protein tyrosine phosphatases.

-	~~{{STRUCTURE_3pxh\| PDB=3pxh \| SCENE= }}~~	+	The Immunoglobulin-like Domains 1 and 2 of the Protein Tyrosine Phosphatase LAR Adopt an Unusual Horseshoe-like Conformation.,Biersmith BH, Hammel M, Geisbrecht ER, Bouyain S J Mol Biol. 2011 May 13;408(4):616-27. Epub 2011 Mar 21. PMID:21402080<ref>PMID:21402080</ref>

-	~~===Tandem Ig domains~~ of ~~tyrosine phosphatase LAR===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_21402080}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3pxh]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Mus_musculus Mus musculus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3PXH OCA].~~	+

	==See Also==		==See Also==
	*[[Tyrosine phosphatase\|Tyrosine phosphatase]]		*[[Tyrosine phosphatase\|Tyrosine phosphatase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:021402080<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Protein-tyrosine-phosphatase]]		[[Category: Protein-tyrosine-phosphatase]]
-	[[Category: Biersmith, B H.]]	+	[[Category: Biersmith, B H]]
-	[[Category: Bouyain, S.]]	+	[[Category: Bouyain, S]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Ig domain]]		[[Category: Ig domain]]
	[[Category: Receptor protein tyrosine phosphatase]]		[[Category: Receptor protein tyrosine phosphatase]]

OCA at 17:51, 20 October 2012

2012-10-20T17:51:13Z

←Older revision		Revision as of 17:51, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3pxh]] is a 1 chain structure ~~of [[Tyrosine phosphatase]]~~ with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PXH OCA].	+	[[3pxh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PXH OCA].

	==See Also==		==See Also==

OCA at 02:12, 27 July 2012

2012-07-27T02:12:44Z

←Older revision		Revision as of 02:12, 27 July 2012
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	[[Image:3pxh.png\|left\|200px]]		[[Image:3pxh.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3pxh", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3pxh\| PDB=3pxh \| SCENE= }}		{{STRUCTURE_3pxh\| PDB=3pxh \| SCENE= }}

	===Tandem Ig domains of tyrosine phosphatase LAR===		===Tandem Ig domains of tyrosine phosphatase LAR===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_21402080}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 21402080 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_21402080}}		{{ABSTRACT_PUBMED_21402080}}

	==About this Structure==		==About this Structure==
-	[[3pxh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PXH OCA].	+	[[3pxh]] is a 1 chain structure of [[Tyrosine phosphatase]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PXH OCA].
		+
		+	==See Also==
		+	*[[Tyrosine phosphatase\|Tyrosine phosphatase]]

	==Reference==		==Reference==
Line 27:		Line 19:
	[[Category: Biersmith, B H.]]		[[Category: Biersmith, B H.]]
	[[Category: Bouyain, S.]]		[[Category: Bouyain, S.]]
		+	[[Category: Cell adhesion]]
		+	[[Category: Hydrolase]]
		+	[[Category: Ig domain]]
		+	[[Category: Receptor protein tyrosine phosphatase]]

OCA at 06:12, 4 May 2011

2011-05-04T06:12:22Z

←Older revision		Revision as of 06:12, 4 May 2011
Line 22:		Line 22:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~21402080~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021402080</ref><references group="xtra"/>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Protein-tyrosine-phosphatase]]		[[Category: Protein-tyrosine-phosphatase]]
	[[Category: Biersmith, B H.]]		[[Category: Biersmith, B H.]]
	[[Category: Bouyain, S.]]		[[Category: Bouyain, S.]]

OCA at 09:52, 21 April 2011

2011-04-21T09:52:02Z

←Older revision		Revision as of 09:52, 21 April 2011
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-	[[Image:3pxh.~~jpg~~\|left\|200px]]	+	[[Image:3pxh.png\|left\|200px]]

	<!--		<!--
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	===Tandem Ig domains of tyrosine phosphatase LAR===		===Tandem Ig domains of tyrosine phosphatase LAR===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21402080}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21402080 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21402080}}

	==About this Structure==		==About this Structure==
	[[3pxh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PXH OCA].		[[3pxh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PXH OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:21402080</ref><references group="xtra"/>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Protein-tyrosine-phosphatase]]		[[Category: Protein-tyrosine-phosphatase]]
	[[Category: Biersmith, B H.]]		[[Category: Biersmith, B H.]]
	[[Category: Bouyain, S.]]		[[Category: Bouyain, S.]]