3q5f - Revision history

OCA at 10:45, 21 February 2024

2024-02-21T10:45:51Z

←Older revision		Revision as of 10:45, 21 February 2024
Line 3:		Line 3:
	<StructureSection load='3q5f' size='340' side='right'caption='[[3q5f]], [[Resolution\|resolution]] 2.96Å' scene=''>		<StructureSection load='3q5f' size='340' side='right'caption='[[3q5f]], [[Resolution\|resolution]] 2.96Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3q5f]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q5F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q5F FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3q5f]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q5F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q5F FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[3qpt\|3qpt]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.96Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">slyA, STM1444 ([https://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q5f OCA], [https://pdbe.org/3q5f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q5f RCSB], [https://www.ebi.ac.uk/pdbsum/3q5f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q5f ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q5f OCA], [https://pdbe.org/3q5f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q5f RCSB], [https://www.ebi.ac.uk/pdbsum/3q5f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q5f ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/SLYA_SALTY SLYA_SALTY]] Transcription regulator that can specifically activate or repress expression of target genes. Required for virulence and survival in the macrophage environment. Probably activates expression of ispA, xseB genes, and of omp operon.<ref>PMID:8544813</ref> <ref>PMID:9284144</ref>	+	[https://www.uniprot.org/uniprot/SLYA_SALTY SLYA_SALTY] Transcription regulator that can specifically activate or repress expression of target genes. Required for virulence and survival in the macrophage environment. Probably activates expression of ispA, xseB genes, and of omp operon.<ref>PMID:8544813</ref> <ref>PMID:9284144</ref>
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	SlyA is a master virulence regulator that controls the transcription of numerous genes in Salmonella enterica. We present here crystal structures of SlyA by itself and bound to a high-affinity DNA operator sequence in the slyA gene. SlyA interacts with DNA through direct recognition of a guanine base by R65, as well as interactions between conserved R86 and the minor groove and a large network of non-base-specific contacts to the sugar-phosphate backbone. Our structures, together with an unpublished structure of SlyA bound to the drug salicylate (PDB: 3DEU), reveal that unlike many other MarR-family proteins, SlyA dissociates from DNA without large conformational changes when bound to this effector. We propose that SlyA and other MarR global regulators rely more on indirect readout of DNA sequence in order to exert control over many genes, in contrast to proteins such as OhrR which recognize a single operator.	+
-		+
-	~~Crystal structures of SlyA, a master virulence regulator of Salmonella, in free and DNA-bound states.,Dolan KT, Duguid EM, He C J Biol Chem. 2011 May 5. PMID:21550983<ref>PMID:21550983</ref>~~	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 3q5f" style="background-color:#fffaf0;"></div~~>	+

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus typhimurium loeffler 1892]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Dolan, K T~~]]	+	[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
-	[[Category: ~~Duguid, E M~~]]	+	[[Category: Dolan KT]]
-	[[Category: ~~Marr/slya protein family]]~~	+	[[Category: Duguid EM]]
-	~~[[Category: Protein-dna complex]]~~	+
-	~~[[Category: Transcription-dna complex]]~~	+
-	~~[[Category: Transcriptonal regulator]]~~	+
-	~~[[Category: Winged helix-turn-helix~~]]	+

OCA at 05:52, 8 June 2022

2022-06-08T05:52:21Z

←Older revision		Revision as of 05:52, 8 June 2022
Line 1:		Line 1:

	==Crystal structure of the Salmonella transcriptional regulator SlyA in complex with DNA==		==Crystal structure of the Salmonella transcriptional regulator SlyA in complex with DNA==
-	<StructureSection load='3q5f' size='340' side='right' caption='[[3q5f]], [[Resolution\|resolution]] 2.96Å' scene=''>	+	<StructureSection load='3q5f' size='340' side='right'caption='[[3q5f]], [[Resolution\|resolution]] 2.96Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3q5f]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q5F OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3Q5F FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3q5f]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q5F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q5F FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3qpt\|3qpt]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3qpt\|3qpt]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">slyA, STM1444 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">slyA, STM1444 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3q5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q5f OCA], [~~http~~://pdbe.org/3q5f PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3q5f RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3q5f PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3q5f ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q5f OCA], [https://pdbe.org/3q5f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q5f RCSB], [https://www.ebi.ac.uk/pdbsum/3q5f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q5f ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/SLYA_SALTY SLYA_SALTY]] Transcription regulator that can specifically activate or repress expression of target genes. Required for virulence and survival in the macrophage environment. Probably activates expression of ispA, xseB genes, and of omp operon.<ref>PMID:8544813</ref> <ref>PMID:9284144</ref>	+	[[https://www.uniprot.org/uniprot/SLYA_SALTY SLYA_SALTY]] Transcription regulator that can specifically activate or repress expression of target genes. Required for virulence and survival in the macrophage environment. Probably activates expression of ispA, xseB genes, and of omp operon.<ref>PMID:8544813</ref> <ref>PMID:9284144</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 3q5f" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3q5f" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Transcriptional activator 3D structures\|Transcriptional activator 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 24:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus typhimurium loeffler 1892]]		[[Category: Bacillus typhimurium loeffler 1892]]
		+	[[Category: Large Structures]]
	[[Category: Dolan, K T]]		[[Category: Dolan, K T]]
	[[Category: Duguid, E M]]		[[Category: Duguid, E M]]

OCA at 07:37, 4 August 2016

2016-08-04T07:37:41Z

←Older revision		Revision as of 07:37, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of the Salmonella transcriptional regulator SlyA in complex with DNA==		==Crystal structure of the Salmonella transcriptional regulator SlyA in complex with DNA==
	<StructureSection load='3q5f' size='340' side='right' caption='[[3q5f]], [[Resolution\|resolution]] 2.96Å' scene=''>		<StructureSection load='3q5f' size='340' side='right' caption='[[3q5f]], [[Resolution\|resolution]] 2.96Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3q5f]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Salmonella_enterica Salmonella enterica~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q5F FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3q5f]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q5F FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3qpt\|3qpt]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3qpt\|3qpt]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">slyA, STM1444 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~28901 Salmonella enterica~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">slyA, STM1444 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q5f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q5f RCSB], [http://www.ebi.ac.uk/pdbsum/3q5f PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q5f OCA], [http://pdbe.org/3q5f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3q5f RCSB], [http://www.ebi.ac.uk/pdbsum/3q5f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3q5f ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3q5f" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Salmonella enterica~~]]	+	[[Category: Bacillus typhimurium loeffler 1892]]
	[[Category: Dolan, K T]]		[[Category: Dolan, K T]]
	[[Category: Duguid, E M]]		[[Category: Duguid, E M]]

OCA at 07:02, 24 December 2014

2014-12-24T07:02:17Z

←Older revision		Revision as of 07:02, 24 December 2014
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q5f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q5f RCSB], [http://www.ebi.ac.uk/pdbsum/3q5f PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q5f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q5f RCSB], [http://www.ebi.ac.uk/pdbsum/3q5f PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SLYA_SALTY SLYA_SALTY]] Transcription regulator that can specifically activate or repress expression of target genes. Required for virulence and survival in the macrophage environment. Probably activates expression of ispA, xseB genes, and of omp operon.<ref>PMID:8544813</ref> <ref>PMID:9284144</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 10:27, 19 December 2014

2014-12-19T10:27:09Z

←Older revision		Revision as of 10:27, 19 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3q5f\| PDB=3q5f \| SCENE= }}~~	+	==Crystal structure of the Salmonella transcriptional regulator SlyA in complex with DNA==
-	===Crystal structure of the Salmonella transcriptional regulator SlyA in complex with DNA===	+	<StructureSection load='3q5f' size='340' side='right' caption='[[3q5f]], [[Resolution\|resolution]] 2.96Å' scene=''>
-	~~{{ABSTRACT_PUBMED_21550983}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3q5f]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica Salmonella enterica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q5F FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3qpt\|3qpt]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">slyA, STM1444 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28901 Salmonella enterica])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q5f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q5f RCSB], [http://www.ebi.ac.uk/pdbsum/3q5f PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	SlyA is a master virulence regulator that controls the transcription of numerous genes in Salmonella enterica. We present here crystal structures of SlyA by itself and bound to a high-affinity DNA operator sequence in the slyA gene. SlyA interacts with DNA through direct recognition of a guanine base by R65, as well as interactions between conserved R86 and the minor groove and a large network of non-base-specific contacts to the sugar-phosphate backbone. Our structures, together with an unpublished structure of SlyA bound to the drug salicylate (PDB: 3DEU), reveal that unlike many other MarR-family proteins, SlyA dissociates from DNA without large conformational changes when bound to this effector. We propose that SlyA and other MarR global regulators rely more on indirect readout of DNA sequence in order to exert control over many genes, in contrast to proteins such as OhrR which recognize a single operator.

-	~~==Function==~~	+	Crystal structures of SlyA, a master virulence regulator of Salmonella, in free and DNA-bound states.,Dolan KT, Duguid EM, He C J Biol Chem. 2011 May 5. PMID:21550983<ref>PMID:21550983</ref>
-	~~[[http://www.uniprot.org/uniprot/SLYA_SALTY SLYA_SALTY]] Transcription~~ regulator ~~that can specifically activate or repress expression~~ of ~~target genes. Required for virulence~~ and ~~survival in the macrophage environment~~. ~~Probably activates expression of ispA~~, ~~xseB genes~~, ~~and of omp operon~~.~~<ref>~~PMID:~~8544813</ref>~~ <ref>PMID:~~9284144~~</ref>	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[3q5f]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Salmonella_enterica Salmonella enterica]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3Q5F OCA].~~	+	</div>
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:021550983</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Salmonella enterica]]		[[Category: Salmonella enterica]]
-	[[Category: Dolan, K T.]]	+	[[Category: Dolan, K T]]
-	[[Category: Duguid, E M.]]	+	[[Category: Duguid, E M]]
	[[Category: Marr/slya protein family]]		[[Category: Marr/slya protein family]]
	[[Category: Protein-dna complex]]		[[Category: Protein-dna complex]]

OCA at 08:24, 8 May 2013

2013-05-08T08:24:47Z

←Older revision		Revision as of 08:24, 8 May 2013
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-	[[Image:3q5f.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3q5f", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3q5f\| PDB=3q5f \| SCENE= }}		{{STRUCTURE_3q5f\| PDB=3q5f \| SCENE= }}
-
	===Crystal structure of the Salmonella transcriptional regulator SlyA in complex with DNA===		===Crystal structure of the Salmonella transcriptional regulator SlyA in complex with DNA===
		+	{{ABSTRACT_PUBMED_21550983}}

-		+	==Function==
-	~~<!--~~	+	[[http://www.uniprot.org/uniprot/SLYA_SALTY SLYA_SALTY]] Transcription regulator that can specifically activate or repress expression of target genes. Required for virulence and survival in the macrophage environment. Probably activates expression of ispA, xseB genes, and of omp operon.<ref>PMID:8544813</ref> <ref>PMID:9284144</ref>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_21550983}}, adds the Publication Abstract to the page~~	+
-	~~(as it appears on PubMed at~~ http://www.~~pubmed~~.~~gov), where 21550983 is~~ the ~~PubMed ID number~~.	+
-	-->	+
-	~~{{ABSTRACT_PUBMED_21550983}}~~	+

	==About this Structure==		==About this Structure==
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	==Reference==		==Reference==
-	<ref group="xtra">PMID:021550983</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021550983</ref><references group="xtra"/><references/>
	[[Category: Salmonella enterica]]		[[Category: Salmonella enterica]]
	[[Category: Dolan, K T.]]		[[Category: Dolan, K T.]]

OCA at 17:56, 6 July 2011

2011-07-06T17:56:53Z

←Older revision		Revision as of 17:56, 6 July 2011
Line 26:		Line 26:
	[[Category: Dolan, K T.]]		[[Category: Dolan, K T.]]
	[[Category: Duguid, E M.]]		[[Category: Duguid, E M.]]
		+	[[Category: Marr/slya protein family]]
		+	[[Category: Protein-dna complex]]
		+	[[Category: Transcription-dna complex]]
		+	[[Category: Transcriptonal regulator]]
		+	[[Category: Winged helix-turn-helix]]

OCA at 05:30, 25 May 2011

2011-05-25T05:30:09Z

←Older revision		Revision as of 05:30, 25 May 2011
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-	[[Image:3q5f.~~jpg~~\|left\|200px]]	+	[[Image:3q5f.png\|left\|200px]]

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	===Crystal structure of the Salmonella transcriptional regulator SlyA in complex with DNA===		===Crystal structure of the Salmonella transcriptional regulator SlyA in complex with DNA===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21550983}}, adds the Publication Abstract to the page
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		+	{{ABSTRACT_PUBMED_21550983}}

	==About this Structure==		==About this Structure==
	[[3q5f]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica Salmonella enterica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q5F OCA].		[[3q5f]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica Salmonella enterica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q5F OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021550983</ref><references group="xtra"/>
	[[Category: Salmonella enterica]]		[[Category: Salmonella enterica]]
	[[Category: Dolan, K T.]]		[[Category: Dolan, K T.]]
	[[Category: Duguid, E M.]]		[[Category: Duguid, E M.]]

OCA at 07:00, 4 May 2011

2011-05-04T07:00:05Z

←Older revision		Revision as of 07:00, 4 May 2011
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-	~~'''Unreleased structure'''~~	+	[[Image:3q5f.jpg\|left\|200px]]

-	The ~~entry 3q5f~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3q5f", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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		+	{{STRUCTURE_3q5f\| PDB=3q5f \| SCENE= }}

-	~~Authors: Dolan, K.T., Duguid, E.M.~~	+	===Crystal structure of the Salmonella transcriptional regulator SlyA in complex with DNA===

-	~~Description: Crystal~~ structure ~~of the Salmonella transcriptional regulator SlyA in complex~~ with ~~DNA~~	+
		+	==About this Structure==
		+	[[3q5f]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica Salmonella enterica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q5F OCA].
		+	[[Category: Salmonella enterica]]
		+	[[Category: Dolan, K T.]]
		+	[[Category: Duguid, E M.]]

OCA at 12:44, 26 January 2011

2011-01-26T12:44:34Z

←Older revision		Revision as of 12:44, 26 January 2011
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3q5f is ON HOLD	+	The entry 3q5f is ON HOLD until Paper Publication

	Authors: Dolan, K.T., Duguid, E.M.		Authors: Dolan, K.T., Duguid, E.M.

	Description: Crystal structure of the Salmonella transcriptional regulator SlyA in complex with DNA		Description: Crystal structure of the Salmonella transcriptional regulator SlyA in complex with DNA