3q7o - Revision history

OCA at 11:35, 14 March 2024

2024-03-14T11:35:58Z

←Older revision		Revision as of 11:35, 14 March 2024
Line 3:		Line 3:
	<StructureSection load='3q7o' size='340' side='right'caption='[[3q7o]], [[Resolution\|resolution]] 2.09Å' scene=''>		<StructureSection load='3q7o' size='340' side='right'caption='[[3q7o]], [[Resolution\|resolution]] 2.09Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3q7o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q7O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3q7o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q7O FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[3q7m\|3q7m]], [[3q7n\|3q7n]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.091Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">yfgL, b2512, JW2496 ([https://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=562 "Bacillus coli" Migula 1895])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7o OCA], [https://pdbe.org/3q7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q7o RCSB], [https://www.ebi.ac.uk/pdbsum/3q7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7o ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7o OCA], [https://pdbe.org/3q7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q7o RCSB], [https://www.ebi.ac.uk/pdbsum/3q7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7o ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/BAMB_ECOLI BAMB_ECOLI]] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex, which may orient the flexible periplasmic domain of BamA for interaction with other Bam components, chaperones and nascent outer membrane proteins.<ref>PMID:20378773</ref> <ref>PMID:21823654</ref> <ref>PMID:21586578</ref> <ref>PMID:21277859</ref>	+	[https://www.uniprot.org/uniprot/BAMB_ECOLI BAMB_ECOLI] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex, which may orient the flexible periplasmic domain of BamA for interaction with other Bam components, chaperones and nascent outer membrane proteins.<ref>PMID:20378773</ref> <ref>PMID:21823654</ref> <ref>PMID:21586578</ref> <ref>PMID:21277859</ref>
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	Escherichia coli BamB is the largest of four lipoproteins in the beta-barrel assembly machinery (BAM) complex. It interacts with the periplasmic domain of BamA, an integral outer membrane protein (OMP) essential for OMP biogenesis. Although BamB is not essential, it serves an important function in the BAM complex, significantly increasing the folding efficiency of some OMPs in vivo and in vitro. To learn more about the BAM complex, we solved structures of BamB in three different crystal forms. BamB crystallized in space groups P2(1)3, I222, and P2(1)2(1)2(1), with one molecule per asymmetric unit in each case. Crystals from the space group I222 diffracted to 1. 65-A resolution. BamB forms an eight-bladed beta-propeller with a central pore and is shaped like a doughnut. A DALI search revealed that BamB shares structural homology to several eukaryotic proteins containing WD40 repeat domains, which commonly have beta-propeller folds and often serve as scaffolding proteins within larger multi-protein complexes that carry out signal transduction, cell division, and chemotaxis. Using mutagenesis data from previous studies, we docked BamB onto a BamA structural model and assessed known and possible interactions between these two proteins. Our data suggest that BamB serves as a scaffolding protein within the BAM complex by optimally orienting the flexible periplasmic domain of BamA for interaction with other BAM components and chaperones. This may facilitate integration of newly synthesized OMPs into the outer membrane.	+
-		+
-	~~The Crystal Structure of BamB Suggests Interactions with BamA and Its Role within the BAM Complex.,Noinaj N, Fairman JW, Buchanan SK J Mol Biol. 2011 Jan 26. PMID:21277859<ref>PMID:21277859</ref>~~	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 3q7o" style="background-color:#fffaf0;"></div~~>	+

	==See Also==		==See Also==
Line 26:		Line 16:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Buchanan~~, S K~~]]	+	[[Category: Buchanan SK]]
-	[[Category: Fairman~~, J W~~]]	+	[[Category: Fairman JW]]
-	[[Category: Noinaj, N]]	+	[[Category: Noinaj N]]
-	~~[[Category: Bam complex]]~~	+
-	~~[[Category: Bama]]~~	+
-	~~[[Category: Beta-propeller]]~~	+
-	~~[[Category: Gram negative]]~~	+
-	~~[[Category: Outer membrane protein folding]]~~	+
-	~~[[Category: Protein binding~~]]	+

OCA at 05:56, 8 June 2022

2022-06-08T05:56:26Z

←Older revision		Revision as of 05:56, 8 June 2022
Line 1:		Line 1:

	==The crystal structure of BamB from the BAM complex in spacegroup P213==		==The crystal structure of BamB from the BAM complex in spacegroup P213==
-	<StructureSection load='3q7o' size='340' side='right' caption='[[3q7o]], [[Resolution\|resolution]] 2.09Å' scene=''>	+	<StructureSection load='3q7o' size='340' side='right'caption='[[3q7o]], [[Resolution\|resolution]] 2.09Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3q7o]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7O OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3Q7O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3q7o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q7O FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3q7m\|3q7m]], [[3q7n\|3q7n]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3q7m\|3q7m]], [[3q7n\|3q7n]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">yfgL, b2512, JW2496 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">yfgL, b2512, JW2496 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3q7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7o OCA], [~~http~~://pdbe.org/3q7o PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3q7o RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3q7o PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7o ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7o OCA], [https://pdbe.org/3q7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q7o RCSB], [https://www.ebi.ac.uk/pdbsum/3q7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7o ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/BAMB_ECOLI BAMB_ECOLI]] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex, which may orient the flexible periplasmic domain of BamA for interaction with other Bam components, chaperones and nascent outer membrane proteins.<ref>PMID:20378773</ref> <ref>PMID:21823654</ref> <ref>PMID:21586578</ref> <ref>PMID:21277859</ref>	+	[[https://www.uniprot.org/uniprot/BAMB_ECOLI BAMB_ECOLI]] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex, which may orient the flexible periplasmic domain of BamA for interaction with other Bam components, chaperones and nascent outer membrane proteins.<ref>PMID:20378773</ref> <ref>PMID:21823654</ref> <ref>PMID:21586578</ref> <ref>PMID:21277859</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 21:

	==See Also==		==See Also==
-	*[[Bam complex\|Bam complex]]	+	*[[Bam complex 3D structures\|Bam complex 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 27:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Buchanan, S K]]		[[Category: Buchanan, S K]]
	[[Category: Fairman, J W]]		[[Category: Fairman, J W]]

OCA at 17:03, 4 August 2016

2016-08-04T17:03:23Z

←Older revision		Revision as of 17:03, 4 August 2016
Line 1:		Line 1:
		+
	==The crystal structure of BamB from the BAM complex in spacegroup P213==		==The crystal structure of BamB from the BAM complex in spacegroup P213==
	<StructureSection load='3q7o' size='340' side='right' caption='[[3q7o]], [[Resolution\|resolution]] 2.09Å' scene=''>		<StructureSection load='3q7o' size='340' side='right' caption='[[3q7o]], [[Resolution\|resolution]] 2.09Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3q7o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q7O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3q7o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q7O FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3q7m\|3q7m]], [[3q7n\|3q7n]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3q7m\|3q7m]], [[3q7n\|3q7n]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">yfgL, b2512, JW2496 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 ~~Escherichia~~ coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">yfgL, b2512, JW2496 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q7o RCSB], [http://www.ebi.ac.uk/pdbsum/3q7o PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7o OCA], [http://pdbe.org/3q7o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3q7o RCSB], [http://www.ebi.ac.uk/pdbsum/3q7o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7o ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~YFGL_ECOLI YFGL_ECOLI~~]] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex, which may orient the flexible periplasmic domain of BamA for interaction with other Bam components, chaperones and nascent outer membrane proteins.<ref>PMID:20378773</ref> <ref>PMID:21823654</ref> <ref>PMID:21586578</ref> <ref>PMID:21277859</ref>	+	[[http://www.uniprot.org/uniprot/BAMB_ECOLI BAMB_ECOLI]] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex, which may orient the flexible periplasmic domain of BamA for interaction with other Bam components, chaperones and nascent outer membrane proteins.<ref>PMID:20378773</ref> <ref>PMID:21823654</ref> <ref>PMID:21586578</ref> <ref>PMID:21277859</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3q7o" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Bam complex\|Bam complex]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Buchanan, S K]]		[[Category: Buchanan, S K]]
	[[Category: Fairman, J W]]		[[Category: Fairman, J W]]

OCA at 11:12, 25 December 2014

2014-12-25T11:12:52Z

←Older revision		Revision as of 11:12, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q7o RCSB], [http://www.ebi.ac.uk/pdbsum/3q7o PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q7o RCSB], [http://www.ebi.ac.uk/pdbsum/3q7o PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/YFGL_ECOLI YFGL_ECOLI]] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex, which may orient the flexible periplasmic domain of BamA for interaction with other Bam components, chaperones and nascent outer membrane proteins.<ref>PMID:20378773</ref> <ref>PMID:21823654</ref> <ref>PMID:21586578</ref> <ref>PMID:21277859</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 10:17, 19 December 2014

2014-12-19T10:17:40Z

←Older revision		Revision as of 10:17, 19 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3q7o\| PDB=3q7o \| SCENE= }}~~	+	==The crystal structure of BamB from the BAM complex in spacegroup P213==
-	===The crystal structure of BamB from the BAM complex in spacegroup P213===	+	<StructureSection load='3q7o' size='340' side='right' caption='[[3q7o]], [[Resolution\|resolution]] 2.09Å' scene=''>
-	~~{{ABSTRACT_PUBMED_21277859}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3q7o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q7O FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3q7m\|3q7m]], [[3q7n\|3q7n]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">yfgL, b2512, JW2496 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q7o RCSB], [http://www.ebi.ac.uk/pdbsum/3q7o PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Escherichia coli BamB is the largest of four lipoproteins in the beta-barrel assembly machinery (BAM) complex. It interacts with the periplasmic domain of BamA, an integral outer membrane protein (OMP) essential for OMP biogenesis. Although BamB is not essential, it serves an important function in the BAM complex, significantly increasing the folding efficiency of some OMPs in vivo and in vitro. To learn more about the BAM complex, we solved structures of BamB in three different crystal forms. BamB crystallized in space groups P2(1)3, I222, and P2(1)2(1)2(1), with one molecule per asymmetric unit in each case. Crystals from the space group I222 diffracted to 1. 65-A resolution. BamB forms an eight-bladed beta-propeller with a central pore and is shaped like a doughnut. A DALI search revealed that BamB shares structural homology to several eukaryotic proteins containing WD40 repeat domains, which commonly have beta-propeller folds and often serve as scaffolding proteins within larger multi-protein complexes that carry out signal transduction, cell division, and chemotaxis. Using mutagenesis data from previous studies, we docked BamB onto a BamA structural model and assessed known and possible interactions between these two proteins. Our data suggest that BamB serves as a scaffolding protein within the BAM complex by optimally orienting the flexible periplasmic domain of BamA for interaction with other BAM components and chaperones. This may facilitate integration of newly synthesized OMPs into the outer membrane.

-	~~==Function==~~	+	The Crystal Structure of BamB Suggests Interactions with BamA and Its Role within the BAM Complex.,Noinaj N, Fairman JW, Buchanan SK J Mol Biol. 2011 Jan 26. PMID:21277859<ref>PMID:21277859</ref>
-	~~[[http://www.uniprot.org/uniprot/YFGL_ECOLI YFGL_ECOLI]] Part~~ of ~~the outer membrane protein assembly complex, which is involved in assembly~~ and ~~insertion of beta-barrel proteins into~~ the ~~outer membrane~~. ~~Nonessential member of the complex~~, ~~which may orient the flexible periplasmic domain of BamA for interaction with other Bam components~~, ~~chaperones and nascent outer membrane proteins~~.~~<ref>~~PMID:~~20378773</ref> <ref>PMID:21823654</ref> <ref>PMID:21586578</ref>~~ <ref>PMID:21277859</ref>	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[3q7o]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7O OCA].~~	+	</div>
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:021277859</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Buchanan, S K.]]	+	[[Category: Buchanan, S K]]
-	[[Category: Fairman, J W.]]	+	[[Category: Fairman, J W]]
-	[[Category: Noinaj, N.]]	+	[[Category: Noinaj, N]]
	[[Category: Bam complex]]		[[Category: Bam complex]]
	[[Category: Bama]]		[[Category: Bama]]

OCA at 08:15, 8 May 2013

2013-05-08T08:15:41Z

←Older revision		Revision as of 08:15, 8 May 2013
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-	[[Image:3q7o.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3q7o", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3q7o\| PDB=3q7o \| SCENE= }}		{{STRUCTURE_3q7o\| PDB=3q7o \| SCENE= }}
-
	===The crystal structure of BamB from the BAM complex in spacegroup P213===		===The crystal structure of BamB from the BAM complex in spacegroup P213===
		+	{{ABSTRACT_PUBMED_21277859}}

-		+	==Function==
-	~~<!--~~	+	[[http://www.uniprot.org/uniprot/YFGL_ECOLI YFGL_ECOLI]] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex, which may orient the flexible periplasmic domain of BamA for interaction with other Bam components, chaperones and nascent outer membrane proteins.<ref>PMID:20378773</ref> <ref>PMID:21823654</ref> <ref>PMID:21586578</ref> <ref>PMID:21277859</ref>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_21277859}}, adds the Publication Abstract to the page~~	+
-	~~(as it appears on PubMed at~~ http://www.~~pubmed~~.~~gov)~~, ~~where 21277859~~ is the ~~PubMed ID number~~.	+
-	-->	+
-	~~{{ABSTRACT_PUBMED_21277859}}~~	+

	==About this Structure==		==About this Structure==
Line 22:		Line 10:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~21277859~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021277859</ref><references group="xtra"/><references/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Buchanan, S K.]]		[[Category: Buchanan, S K.]]
	[[Category: Fairman, J W.]]		[[Category: Fairman, J W.]]
	[[Category: Noinaj, N.]]		[[Category: Noinaj, N.]]
		+	[[Category: Bam complex]]
		+	[[Category: Bama]]
		+	[[Category: Beta-propeller]]
		+	[[Category: Gram negative]]
		+	[[Category: Outer membrane protein folding]]
		+	[[Category: Protein binding]]

OCA at 05:53, 23 March 2011

2011-03-23T05:53:41Z

←Older revision		Revision as of 05:53, 23 March 2011
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-	[[Image:3q7o.~~jpg~~\|left\|200px]]	+	[[Image:3q7o.png\|left\|200px]]

	<!--		<!--

OCA at 06:14, 9 February 2011

2011-02-09T06:14:49Z

←Older revision		Revision as of 06:14, 9 February 2011
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-	~~'''Unreleased structure'''~~	+	[[Image:3q7o.jpg\|left\|200px]]

-	The ~~entry 3q7o~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3q7o", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3q7o\| PDB=3q7o \| SCENE= }}

-	~~Authors: Noinaj, N., Fairman, J.W., Buchanan, S.K.~~	+	===The crystal structure of BamB from the BAM complex in spacegroup P213===

-	~~Description:~~ The ~~crystal~~ structure ~~of BamB~~ from ~~the BAM complex in spacegroup P213~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21277859}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21277859 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21277859}}
		+
		+	==About this Structure==
		+	[[3q7o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7O OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:21277859</ref><references group="xtra"/>
		+	[[Category: Escherichia coli]]
		+	[[Category: Buchanan, S K.]]
		+	[[Category: Fairman, J W.]]
		+	[[Category: Noinaj, N.]]

OCA at 12:44, 26 January 2011

2011-01-26T12:44:56Z

←Older revision		Revision as of 12:44, 26 January 2011
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3q7o is ON HOLD	+	The entry 3q7o is ON HOLD until Paper Publication

	Authors: Noinaj, N., Fairman, J.W., Buchanan, S.K.		Authors: Noinaj, N., Fairman, J.W., Buchanan, S.K.

	Description: The crystal structure of BamB from the BAM complex in spacegroup P213		Description: The crystal structure of BamB from the BAM complex in spacegroup P213

OCA: Protected "3q7o" [edit=sysop:move=sysop]

2011-01-12T04:51:50Z

Protected "3q7o" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:51, 12 January 2011