3ra9 - Revision history

OCA at 10:53, 21 February 2024

2024-02-21T10:53:21Z

←Older revision		Revision as of 10:53, 21 February 2024
Line 3:		Line 3:
	<StructureSection load='3ra9' size='340' side='right'caption='[[3ra9]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='3ra9' size='340' side='right'caption='[[3ra9]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ra9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ ] and [https://en.wikipedia.org/wiki/~~Adeno-associated_virus_-_8 Adeno-associated virus - 8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RA9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ra9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Adeno-associated_virus_-_8 Adeno-associated virus - 8] and [https://en.wikipedia.org/wiki/Aequorea_victoria Aequorea victoria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RA9 FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[3ra2\|3ra2]]~~, [[~~3ra4~~\|~~3ra4~~]]~~, [[3ra8\|3ra8]], [[3raa\|3raa]]</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.7Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ra9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ra9 OCA], [https://pdbe.org/3ra9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ra9 RCSB], [https://www.ebi.ac.uk/pdbsum/3ra9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ra9 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ra9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ra9 OCA], [https://pdbe.org/3ra9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ra9 RCSB], [https://www.ebi.ac.uk/pdbsum/3ra9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ra9 ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/Q8JQF8_9VIRU Q8JQF8_9VIRU]
-	The ssDNA parvoviruses enter host cells through receptor-mediated endocytosis and infection depends on processing in the early to late endosome as well as the lysosome prior to nuclear entry for replication. However, the mechanisms of capsid endosomal processing, including the effects of low pH, are poorly understood. To gain insight into the structural transitions required for this essential step in infection, the crystal structures of empty and GFP gene packaged Adeno-associated virus (AAV) serotype 8 (AAV8) has been determined at pHs 6.0, 5.5, and 4.0, and then at 7.5 after incubation at 4.0, mimicking the conditions encountered during endocytic trafficking. While the capsid viral protein (VP) topologies of all the structures were similar, significant amino acid side-chain conformational rearrangements were observed on (I) the interior surface of the capsid under the icosahedral three-fold axis near ordered nucleic acid density that was lost concomitant with the conformational change as pH was reduced and (II) the exterior capsid surface close to the icosahedral two-fold depression. The three-fold change is consistent with DNA release from an ordering interaction on the inside surface of the capsid at low pH and suggests transitions that likely trigger the capsid for genome uncoating. The surface change results in disruption of VP:VP interface interactions and a decrease in buried surface area between VP monomers. This disruption points to capsid destabilization which may (I) release VP1 amino acids for its phospholipase A2 function for endosomal escape and nuclear localization signals for nuclear targeting and (II) trigger genome uncoating.	+
-		+
-	Structural studies of AAV8 capsid transitions associated with endosomal trafficking.,Nam HJ, Gurda BL, McKenna R, Potter M, Byrne B, Salganik M, Muzyczka N, Agbandje-McKenna M J Virol. 2011 Sep 7. PMID:21900159<ref>PMID:21900159</~~ref>~~	+
-		+
-	~~From MEDLINE®~~/~~PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 3ra9" style="background-color:#fffaf0;"><~~/~~div>~~	+

	==See Also==		==See Also==
	*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]		*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Adeno-associated virus - 8]]		[[Category: Adeno-associated virus - 8]]
		+	[[Category: Aequorea victoria]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Agbandje-McKenna, M]]	+	[[Category: Agbandje-McKenna M]]
-	[[Category: Byrne, B]]	+	[[Category: Byrne B]]
-	[[Category: Gurda, B]]	+	[[Category: Gurda B]]
-	[[Category: McKenna, R]]	+	[[Category: McKenna R]]
-	[[Category: Muzyczka, N]]	+	[[Category: Muzyczka N]]
-	[[Category: Nam, H J]]	+	[[Category: Nam H-J]]
-	[[Category: Porter, M]]	+	[[Category: Porter M]]
-	[[Category: Salganik, M]]	+	[[Category: Salganik M]]
-	~~[[Category: Beta barrel]]~~	+
-	~~[[Category: Viral capsid]]~~	+
-	~~[[Category: Virus~~]]	+

OCA at 05:55, 15 June 2022

2022-06-15T05:55:17Z

←Older revision		Revision as of 05:55, 15 June 2022
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	==Structural studies of AAV8 capsid transitions associated with endosomal trafficking==		==Structural studies of AAV8 capsid transitions associated with endosomal trafficking==
-	<StructureSection load='3ra9' size='340' side='right' caption='[[3ra9]], [[Resolution\|resolution]] 2.70Å' scene=''>	+	<StructureSection load='3ra9' size='340' side='right'caption='[[3ra9]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ra9]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/ ] and [~~http~~://en.wikipedia.org/wiki/Adeno-associated_virus_-_8 Adeno-associated virus - 8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RA9 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3RA9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ra9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ ] and [https://en.wikipedia.org/wiki/Adeno-associated_virus_-_8 Adeno-associated virus - 8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RA9 FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ra2\|3ra2]], [[3ra4\|3ra4]], [[3ra8\|3ra8]], [[3raa\|3raa]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3ra2\|3ra2]], [[3ra4\|3ra4]], [[3ra8\|3ra8]], [[3raa\|3raa]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ra9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ra9 OCA], [~~http~~://pdbe.org/3ra9 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3ra9 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3ra9 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3ra9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ra9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ra9 OCA], [https://pdbe.org/3ra9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ra9 RCSB], [https://www.ebi.ac.uk/pdbsum/3ra9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ra9 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 18:		Line 18:

	==See Also==		==See Also==
-	*[[Virus coat ~~protein~~\|Virus coat ~~protein~~]]	+	*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 24:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Adeno-associated virus - 8]]		[[Category: Adeno-associated virus - 8]]
		+	[[Category: Large Structures]]
	[[Category: Agbandje-McKenna, M]]		[[Category: Agbandje-McKenna, M]]
	[[Category: Byrne, B]]		[[Category: Byrne, B]]

OCA at 15:54, 4 August 2016

2016-08-04T15:54:21Z

←Older revision		Revision as of 15:54, 4 August 2016
Line 1:		Line 1:
		+
	==Structural studies of AAV8 capsid transitions associated with endosomal trafficking==		==Structural studies of AAV8 capsid transitions associated with endosomal trafficking==
	<StructureSection load='3ra9' size='340' side='right' caption='[[3ra9]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='3ra9' size='340' side='right' caption='[[3ra9]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ra9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Adeno-associated_virus_-_8 Adeno-associated virus - 8~~] and [http://en.wikipedia.org/wiki/~~Aequorea_victoria Aequorea victoria~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RA9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RA9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ra9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Adeno-associated_virus_-_8 Adeno-associated virus - 8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RA9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RA9 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ra2\|3ra2]], [[3ra4\|3ra4]], [[3ra8\|3ra8]], [[3raa\|3raa]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ra2\|3ra2]], [[3ra4\|3ra4]], [[3ra8\|3ra8]], [[3raa\|3raa]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ra9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ra9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ra9 RCSB], [http://www.ebi.ac.uk/pdbsum/3ra9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ra9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ra9 OCA], [http://pdbe.org/3ra9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ra9 RCSB], [http://www.ebi.ac.uk/pdbsum/3ra9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ra9 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3ra9" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 22:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Adeno-associated virus - 8]]		[[Category: Adeno-associated virus - 8]]
-	[[Category: Aequorea victoria]]
	[[Category: Agbandje-McKenna, M]]		[[Category: Agbandje-McKenna, M]]
	[[Category: Byrne, B]]		[[Category: Byrne, B]]

OCA at 10:24, 19 December 2014

2014-12-19T10:24:27Z

←Older revision		Revision as of 10:24, 19 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3ra9\| PDB=3ra9 \| SCENE= }}~~	+	==Structural studies of AAV8 capsid transitions associated with endosomal trafficking==
-	===Structural studies of AAV8 capsid transitions associated with endosomal trafficking===	+	<StructureSection load='3ra9' size='340' side='right' caption='[[3ra9]], [[Resolution\|resolution]] 2.70Å' scene=''>
-	~~{{ABSTRACT_PUBMED_21900159}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3ra9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Adeno-associated_virus_-_8 Adeno-associated virus - 8] and [http://en.wikipedia.org/wiki/Aequorea_victoria Aequorea victoria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RA9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RA9 FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ra2\|3ra2]], [[3ra4\|3ra4]], [[3ra8\|3ra8]], [[3raa\|3raa]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ra9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ra9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ra9 RCSB], [http://www.ebi.ac.uk/pdbsum/3ra9 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The ssDNA parvoviruses enter host cells through receptor-mediated endocytosis and infection depends on processing in the early to late endosome as well as the lysosome prior to nuclear entry for replication. However, the mechanisms of capsid endosomal processing, including the effects of low pH, are poorly understood. To gain insight into the structural transitions required for this essential step in infection, the crystal structures of empty and GFP gene packaged Adeno-associated virus (AAV) serotype 8 (AAV8) has been determined at pHs 6.0, 5.5, and 4.0, and then at 7.5 after incubation at 4.0, mimicking the conditions encountered during endocytic trafficking. While the capsid viral protein (VP) topologies of all the structures were similar, significant amino acid side-chain conformational rearrangements were observed on (I) the interior surface of the capsid under the icosahedral three-fold axis near ordered nucleic acid density that was lost concomitant with the conformational change as pH was reduced and (II) the exterior capsid surface close to the icosahedral two-fold depression. The three-fold change is consistent with DNA release from an ordering interaction on the inside surface of the capsid at low pH and suggests transitions that likely trigger the capsid for genome uncoating. The surface change results in disruption of VP:VP interface interactions and a decrease in buried surface area between VP monomers. This disruption points to capsid destabilization which may (I) release VP1 amino acids for its phospholipase A2 function for endosomal escape and nuclear localization signals for nuclear targeting and (II) trigger genome uncoating.

-	~~==About this Structure==~~	+	Structural studies of AAV8 capsid transitions associated with endosomal trafficking.,Nam HJ, Gurda BL, McKenna R, Potter M, Byrne B, Salganik M, Muzyczka N, Agbandje-McKenna M J Virol. 2011 Sep 7. PMID:21900159<ref>PMID:21900159</ref>
-	~~[[3ra9]] is a 2 chain structure~~ with ~~sequence from [http://en~~.~~wikipedia.org/wiki/Adeno~~-~~associated_virus_-_8 Adeno-associated virus - 8] and [http://en~~.~~wikipedia~~.~~org/wiki/Aequorea_victoria Aequorea victoria]. Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3RA9 OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group~~=~~"xtra">PMID:021900159</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+
		+	==See Also==
		+	*[[Virus coat protein\|Virus coat protein]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Adeno-associated virus - 8]]		[[Category: Adeno-associated virus - 8]]
	[[Category: Aequorea victoria]]		[[Category: Aequorea victoria]]
-	[[Category: Agbandje-McKenna, M.]]	+	[[Category: Agbandje-McKenna, M]]
-	[[Category: Byrne, B.]]	+	[[Category: Byrne, B]]
-	[[Category: Gurda, B.]]	+	[[Category: Gurda, B]]
-	[[Category: McKenna, R.]]	+	[[Category: McKenna, R]]
-	[[Category: Muzyczka, N.]]	+	[[Category: Muzyczka, N]]
-	[[Category: Nam, H J.]]	+	[[Category: Nam, H J]]
-	[[Category: Porter, M.]]	+	[[Category: Porter, M]]
-	[[Category: Salganik, M.]]	+	[[Category: Salganik, M]]
	[[Category: Beta barrel]]		[[Category: Beta barrel]]
	[[Category: Viral capsid]]		[[Category: Viral capsid]]
	[[Category: Virus]]		[[Category: Virus]]

OCA at 07:39, 30 June 2013

2013-06-30T07:39:26Z

←Older revision		Revision as of 07:39, 30 June 2013
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-	[[Image:3ra9.png\|left\|200px]]
-
	{{STRUCTURE_3ra9\| PDB=3ra9 \| SCENE= }}		{{STRUCTURE_3ra9\| PDB=3ra9 \| SCENE= }}
-
	===Structural studies of AAV8 capsid transitions associated with endosomal trafficking===		===Structural studies of AAV8 capsid transitions associated with endosomal trafficking===
-
	{{ABSTRACT_PUBMED_21900159}}		{{ABSTRACT_PUBMED_21900159}}

	==About this Structure==		==About this Structure==
-	[[3ra9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Aequorea_victoria Aequorea victoria~~] and [http://en.wikipedia.org/wiki/~~Viruses Viruses~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RA9 OCA].	+	[[3ra9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Adeno-associated_virus_-_8 Adeno-associated virus - 8] and [http://en.wikipedia.org/wiki/Aequorea_victoria Aequorea victoria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RA9 OCA].
-		+
-	~~==See Also==~~	+
-	*[[Virus coat protein\|Virus coat protein]]	+

	==Reference==		==Reference==
-	<ref group="xtra">PMID:021900159</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021900159</ref><references group="xtra"/><references/>
		+	[[Category: Adeno-associated virus - 8]]
	[[Category: Aequorea victoria]]		[[Category: Aequorea victoria]]
-	[[Category: Viruses]]
	[[Category: Agbandje-McKenna, M.]]		[[Category: Agbandje-McKenna, M.]]
	[[Category: Byrne, B.]]		[[Category: Byrne, B.]]

OCA at 15:47, 20 October 2012

2012-10-20T15:47:54Z

←Older revision		Revision as of 15:47, 20 October 2012
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-	[[Image:3ra9.~~jpg~~\|left\|200px]]	+	[[Image:3ra9.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3ra9", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3ra9\| PDB=3ra9 \| SCENE= }}		{{STRUCTURE_3ra9\| PDB=3ra9 \| SCENE= }}

	===Structural studies of AAV8 capsid transitions associated with endosomal trafficking===		===Structural studies of AAV8 capsid transitions associated with endosomal trafficking===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_21900159}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 21900159 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_21900159}}		{{ABSTRACT_PUBMED_21900159}}

	==About this Structure==		==About this Structure==
	[[3ra9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aequorea_victoria Aequorea victoria] and [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RA9 OCA].		[[3ra9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aequorea_victoria Aequorea victoria] and [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RA9 OCA].
		+
		+	==See Also==
		+	*[[Virus coat protein\|Virus coat protein]]

	==Reference==		==Reference==

OCA at 05:50, 21 September 2011

2011-09-21T05:50:24Z

←Older revision		Revision as of 05:50, 21 September 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3ra9.jpg\|left\|200px]]

-	The ~~entry 3ra9~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3ra9", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3ra9\| PDB=3ra9 \| SCENE= }}

-	~~Authors: Nam, H.-J., Gurda, B., McKenna, R., Porter, M., Byrne, B., Salganik, M., Muzyczka, N., Agbandje-McKenna, M.~~	+	===Structural studies of AAV8 capsid transitions associated with endosomal trafficking===

-	~~Description~~: ~~Structural studies of AAV8 capsid transitions associated~~ with ~~endosomal trafficking~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21900159}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21900159 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21900159}}
		+
		+	==About this Structure==
		+	[[3ra9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aequorea_victoria Aequorea victoria] and [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RA9 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021900159</ref><references group="xtra"/>
		+	[[Category: Aequorea victoria]]
		+	[[Category: Viruses]]
		+	[[Category: Agbandje-McKenna, M.]]
		+	[[Category: Byrne, B.]]
		+	[[Category: Gurda, B.]]
		+	[[Category: McKenna, R.]]
		+	[[Category: Muzyczka, N.]]
		+	[[Category: Nam, H J.]]
		+	[[Category: Porter, M.]]
		+	[[Category: Salganik, M.]]
		+	[[Category: Beta barrel]]
		+	[[Category: Viral capsid]]
		+	[[Category: Virus]]

OCA at 05:38, 29 June 2011

2011-06-29T05:38:14Z

←Older revision		Revision as of 05:38, 29 June 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3ra9 is ON HOLD	+	The entry 3ra9 is ON HOLD until Paper Publication

	Authors: Nam, H.-J., Gurda, B., McKenna, R., Porter, M., Byrne, B., Salganik, M., Muzyczka, N., Agbandje-McKenna, M.		Authors: Nam, H.-J., Gurda, B., McKenna, R., Porter, M., Byrne, B., Salganik, M., Muzyczka, N., Agbandje-McKenna, M.

	Description: Structural studies of AAV8 capsid transitions associated with endosomal trafficking		Description: Structural studies of AAV8 capsid transitions associated with endosomal trafficking

OCA at 04:48, 8 June 2011

2011-06-08T04:48:33Z

←Older revision		Revision as of 04:48, 8 June 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3ra9 is ON HOLD ~~until sometime in the future~~	+	The entry 3ra9 is ON HOLD

-	Authors: Nam, H.-J., Gurda, B., McKenna, R., Porter, M., Byrne, B., Salganik, M, Muzyczka, N., Agbandje-McKenna, M	+	Authors: Nam, H.-J., Gurda, B., McKenna, R., Porter, M., Byrne, B., Salganik, M., Muzyczka, N., Agbandje-McKenna, M.

	Description: Structural studies of AAV8 capsid transitions associated with endosomal trafficking		Description: Structural studies of AAV8 capsid transitions associated with endosomal trafficking

OCA: Protected "3ra9" [edit=sysop:move=sysop]

2011-04-06T08:41:26Z

Protected "3ra9" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:41, 6 April 2011