3rtj - Revision history

OCA at 10:24, 22 June 2022

2022-06-22T10:24:33Z

←Older revision		Revision as of 10:24, 22 June 2022
Line 1:		Line 1:

	==Crystal structure of ricin bound with dinucleotide ApG==		==Crystal structure of ricin bound with dinucleotide ApG==
-	<StructureSection load='3rtj' size='340' side='right' caption='[[3rtj]], [[Resolution\|resolution]] 3.00Å' scene=''>	+	<StructureSection load='3rtj' size='340' side='right'caption='[[3rtj]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3rtj]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Ricinus_communis Ricinus communis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1apg 1apg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RTJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3RTJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3rtj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Ricinus_communis Ricinus communis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1apg 1apg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RTJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RTJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2aai\|2aai]], [[3rti\|3rti]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2aai\|2aai]], [[3rti\|3rti]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3rtj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rtj OCA], [~~http~~://pdbe.org/3rtj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3rtj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3rtj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3rtj ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rtj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rtj OCA], [https://pdbe.org/3rtj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rtj RCSB], [https://www.ebi.ac.uk/pdbsum/3rtj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rtj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RICI_RICCO RICI_RICCO]] Ricin is highly toxic to animal cells and to a lesser extent to plant cells. The A chain acts as a glycosidase that removes a specific adenine residue from an exposed loop of the 28S rRNA (A4324 in mammals), leading to rRNA breakage. As this loop is involved in elongation factor binding, modified ribosomes are catalytically inactive and unable to support protein synthesis. The A chain can inactivate a few thousand ribosomes per minute, faster than the cell can make new ones. Therefore a single A chain molecule can kill an animal cell. The B chain binds to beta-D-galactopyranoside moieties on cell surface glycoproteins and glycolipids and facilitates the entry into the cell of the A chain; B chains are also responsible for cell agglutination (Lectin activity).	+	[[https://www.uniprot.org/uniprot/RICI_RICCO RICI_RICCO]] Ricin is highly toxic to animal cells and to a lesser extent to plant cells. The A chain acts as a glycosidase that removes a specific adenine residue from an exposed loop of the 28S rRNA (A4324 in mammals), leading to rRNA breakage. As this loop is involved in elongation factor binding, modified ribosomes are catalytically inactive and unable to support protein synthesis. The A chain can inactivate a few thousand ribosomes per minute, faster than the cell can make new ones. Therefore a single A chain molecule can kill an animal cell. The B chain binds to beta-D-galactopyranoside moieties on cell surface glycoproteins and glycolipids and facilitates the entry into the cell of the A chain; B chains are also responsible for cell agglutination (Lectin activity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 23:
	==See Also==		==See Also==
	*[[Ricin\|Ricin]]		*[[Ricin\|Ricin]]
		+	*[[Ricin 3D structures\|Ricin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Ricinus communis]]		[[Category: Ricinus communis]]
	[[Category: RRNA N-glycosylase]]		[[Category: RRNA N-glycosylase]]

OCA at 08:17, 5 August 2016

2016-08-05T08:17:30Z

←Older revision		Revision as of 08:17, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of ricin bound with dinucleotide ApG==		==Crystal structure of ricin bound with dinucleotide ApG==
	<StructureSection load='3rtj' size='340' side='right' caption='[[3rtj]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='3rtj' size='340' side='right' caption='[[3rtj]], [[Resolution\|resolution]] 3.00Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2aai\|2aai]], [[3rti\|3rti]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2aai\|2aai]], [[3rti\|3rti]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rtj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rtj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rtj RCSB], [http://www.ebi.ac.uk/pdbsum/3rtj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rtj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rtj OCA], [http://pdbe.org/3rtj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3rtj RCSB], [http://www.ebi.ac.uk/pdbsum/3rtj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3rtj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3rtj" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 00:37, 25 December 2014

2014-12-25T00:37:53Z

←Older revision		Revision as of 00:37, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3rtj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Ricinus_communis Ricinus communis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1apg 1apg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RTJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RTJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[3rtj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Ricinus_communis Ricinus communis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1apg 1apg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RTJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RTJ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2aai\|2aai]], [[3rti\|3rti]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2aai\|2aai]], [[3rti\|3rti]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rtj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rtj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rtj RCSB], [http://www.ebi.ac.uk/pdbsum/3rtj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rtj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rtj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rtj RCSB], [http://www.ebi.ac.uk/pdbsum/3rtj PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RICI_RICCO RICI_RICCO]] Ricin is highly toxic to animal cells and to a lesser extent to plant cells. The A chain acts as a glycosidase that removes a specific adenine residue from an exposed loop of the 28S rRNA (A4324 in mammals), leading to rRNA breakage. As this loop is involved in elongation factor binding, modified ribosomes are catalytically inactive and unable to support protein synthesis. The A chain can inactivate a few thousand ribosomes per minute, faster than the cell can make new ones. Therefore a single A chain molecule can kill an animal cell. The B chain binds to beta-D-galactopyranoside moieties on cell surface glycoproteins and glycolipids and facilitates the entry into the cell of the A chain; B chains are also responsible for cell agglutination (Lectin activity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 14:		Line 16:
	X-ray analysis of substrate analogs in the ricin A-chain active site.,Monzingo AF, Robertus JD J Mol Biol. 1992 Oct 20;227(4):1136-45. PMID:1433290<ref>PMID:1433290</ref>		X-ray analysis of substrate analogs in the ricin A-chain active site.,Monzingo AF, Robertus JD J Mol Biol. 1992 Oct 20;227(4):1136-45. PMID:1433290<ref>PMID:1433290</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>

Line 25:		Line 27:
	[[Category: Ricinus communis]]		[[Category: Ricinus communis]]
	[[Category: RRNA N-glycosylase]]		[[Category: RRNA N-glycosylase]]
-	[[Category: Monzingo, A F.]]	+	[[Category: Monzingo, A F]]
-	[[Category: Robertus, J D.]]	+	[[Category: Robertus, J D]]
	[[Category: Enzyme-substrate complex]]		[[Category: Enzyme-substrate complex]]
	[[Category: Glycosidase ribosome-inactivating protein lectin glycoprotein]]		[[Category: Glycosidase ribosome-inactivating protein lectin glycoprotein]]

OCA at 04:49, 5 June 2014

2014-06-05T04:49:37Z

←Older revision		Revision as of 04:49, 5 June 2014
Line 1:		Line 1:
-	[[~~Image:~~3rtj.~~jpg~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of ricin bound with dinucleotide ApG==
		+	<StructureSection load='3rtj' size='340' side='right' caption='[[3rtj]], [[Resolution\|resolution]] 3.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3rtj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Ricinus_communis Ricinus communis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1apg 1apg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RTJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RTJ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2aai\|2aai]], [[3rti\|3rti]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rtj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rtj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rtj RCSB], [http://www.ebi.ac.uk/pdbsum/3rtj PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Ricin A-chain is an N-glycosidase that hydrolyzes the adenine ring from a specific adenosine of rRNA. Formycin monophosphate (FMP) and adenyl(3'-->5')guanosine (ApG) were bound to ricin A-chain and their structures elucidated by X-ray crystallography. The formycin ring stacks between tyrosines 80 and 123 and at least four hydrogen bonds are made to the adenine moiety. A residue invariant in this enzyme class, Arg180, appears to hydrogen bond to N-3 of the susceptible adenine. Three hypothetical models for binding a true hexanucleotide substrate, CGAGAG, are proposed. They incorporate adenine binding, shown by crystallography, but also include geometry likely to favor catalysis. For example, efforts have been made to orient the ribose ring in a way that allows solvent attack and oxycarbonium stabilization by the enzyme. The favored model is a simple perturbation of the tetraloop structure determined by nuclear magnetic resonance for similar polynucleotides. The model is attractive in that specific roles are defined for conserved protein residues. A mechanism of action is proposed. It invokes oxycarbonium ion stabilization on ribose by Glu177 in the transition state. Arg180 stabilizes anion development on the leaving adenine by protonation at N-3 and may activate a trapped water molecule that is the ultimate nucleophile in the depurination.

-	<!--	+	X-ray analysis of substrate analogs in the ricin A-chain active site.,Monzingo AF, Robertus JD J Mol Biol. 1992 Oct 20;227(4):1136-45. PMID:1433290<ref>PMID:1433290</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_3rtj"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_3rtj\| PDB=3rtj \| SCENE= }}~~	+

-	~~===Crystal structure~~ of ~~ricin bound with dinucleotide ApG===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-		+	==See Also==
-	~~<!--~~	+	*[[Ricin\|Ricin]]
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_1433290}}, adds the Publication Abstract to the page~~	+	== References ==
-	~~(as it appears on PubMed at http://www.pubmed.gov), where 1433290 is the PubMed ID number.~~	+	<references/>
-	~~-->~~	+	__TOC__
-	~~{{ABSTRACT_PUBMED_1433290}}~~	+	</StructureSection>
-		+
-	==~~About this Structure~~==	+
-	[[~~3rtj~~]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Ricinus_communis Ricinus communis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1apg 1apg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RTJ OCA].	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:001433290<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Ricinus communis]]		[[Category: Ricinus communis]]
	[[Category: RRNA N-glycosylase]]		[[Category: RRNA N-glycosylase]]

OCA at 06:41, 31 August 2011

2011-08-31T06:41:50Z

←Older revision		Revision as of 06:41, 31 August 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3rtj.jpg\|left\|200px]]

-	The ~~entry 3rtj~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3rtj", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3rtj\| PDB=3rtj \| SCENE= }}

-	~~Authors: Monzingo, A.F., Robertus, J.D.~~	+	===Crystal structure of ricin bound with dinucleotide ApG===

-	~~Description~~: ~~Crystal~~ structure ~~of ricin bound~~ with ~~dinucleotide ApG~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_1433290}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 1433290 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_1433290}}
		+
		+	==About this Structure==
		+	[[3rtj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Ricinus_communis Ricinus communis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1apg 1apg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RTJ OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:001433290</ref><references group="xtra"/>
		+	[[Category: Ricinus communis]]
		+	[[Category: RRNA N-glycosylase]]
		+	[[Category: Monzingo, A F.]]
		+	[[Category: Robertus, J D.]]
		+	[[Category: Enzyme-substrate complex]]
		+	[[Category: Glycosidase ribosome-inactivating protein lectin glycoprotein]]
		+	[[Category: Glycosylation]]
		+	[[Category: Hydrolase]]
		+	[[Category: Hydrolase-rna complex]]
		+	[[Category: Lactose binding]]

OCA: Protected "3rtj" [edit=sysop:move=sysop]

2011-05-12T04:24:18Z

Protected "3rtj" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:24, 12 May 2011

OCA: New page: '''Unreleased structure''' The entry 3rtj is ON HOLD Authors: Monzingo, A.F., Robertus, J.D. Description: Crystal structure of ricin bound with dinucleotide ApG

2011-05-12T04:24:17Z

New page: '''Unreleased structure''' The entry 3rtj is ON HOLD Authors: Monzingo, A.F., Robertus, J.D. Description: Crystal structure of ricin bound with dinucleotide ApG

New page

'''Unreleased structure'''

The entry 3rtj is ON HOLD

Authors: Monzingo, A.F., Robertus, J.D.

Description: Crystal structure of ricin bound with dinucleotide ApG