3sbg - Revision history

OCA at 09:49, 1 March 2024

2024-03-01T09:49:12Z

←Older revision		Revision as of 09:49, 1 March 2024
Line 3:		Line 3:
	<StructureSection load='3sbg' size='340' side='right'caption='[[3sbg]], [[Resolution\|resolution]] 3.28Å' scene=''>		<StructureSection load='3sbg' size='340' side='right'caption='[[3sbg]], [[Resolution\|resolution]] 3.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3sbg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Baker's_yeast Baker's yeast~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SBG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3sbg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SBG FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[3sbs\|3sbs]], [[3sbt\|3sbt]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.28Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">DBF3, DNA39, PRP8, RNA8, SLT21, USA2, YHR165C ([https://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=559292 Baker's yeast])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sbg OCA], [https://pdbe.org/3sbg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sbg RCSB], [https://www.ebi.ac.uk/pdbsum/3sbg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sbg ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sbg OCA], [https://pdbe.org/3sbg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sbg RCSB], [https://www.ebi.ac.uk/pdbsum/3sbg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sbg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/PRP8_YEAST PRP8_YEAST]] Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. Also has a role in cell cycle.<ref>PMID:2835658</ref> <ref>PMID:9150140</ref> <ref>PMID:12773561</ref> <ref>PMID:18779563</ref>	+	[https://www.uniprot.org/uniprot/PRP8_YEAST PRP8_YEAST] Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. Also has a role in cell cycle.<ref>PMID:2835658</ref> <ref>PMID:9150140</ref> <ref>PMID:12773561</ref> <ref>PMID:18779563</ref>
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	Little is known about how particle-specific proteins are assembled on spliceosomal small nuclear ribonucleoproteins (snRNPs). Brr2p is a U5 snRNP-specific RNA helicase required for spliceosome catalytic activation and disassembly. In yeast, the Aar2 protein is part of a cytoplasmic precursor U5 snRNP that lacks Brr2p and is replaced by Brr2p in the nucleus. Here we show that Aar2p and Brr2p bind to different domains in the C-terminal region of Prp8p; Aar2p interacts with the RNaseH domain, whereas Brr2p interacts with the Jab1/MPN domain. These domains are connected by a long, flexible linker, but the Aar2p-RNaseH complex sequesters the Jab1/MPN domain, thereby preventing binding by Brr2p. Aar2p is phosphorylated in vivo, and a phospho-mimetic S253E mutation in Aar2p leads to disruption of the Aar2p-Prp8p complex in favor of the Brr2p-Prp8p complex. We propose a model in which Aar2p acts as a phosphorylation-controlled U5 snRNP assembly factor that regulates the incorporation of the particle-specific Brr2p. The purpose of this regulation may be to safeguard against nonspecific RNA binding to Prp8p and/or premature activation of Brr2p activity.	+
-		+
-	Mechanism for Aar2p function as a U5 snRNP assembly factor.,Weber G, Cristao VF, Alves FD, Santos KF, Holton N, Rappsilber J, Beggs JD, Wahl MC Genes Dev. 2011 Jul 15. PMID:21764848<ref>PMID:21764848</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 3sbg" style="background-color:#fffaf0;"></div~~>	+

	==See Also==		==See Also==
Line 26:		Line 16:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Baker's yeast]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Holton, N]]	+	[[Category: Saccharomyces cerevisiae S288C]]
-	[[Category: Santos, K]]	+	[[Category: Holton N]]
-	[[Category: Wahl~~, M C~~]]	+	[[Category: Santos K]]
-	[[Category: Weber, G]]	+	[[Category: Wahl MC]]
-	~~[[Category: Jab1/mpn domain]]~~	+	[[Category: Weber G]]
-	~~[[Category: Prp8p]]~~	+
-	~~[[Category: Rnaseh domain]]~~	+
-	~~[[Category: Splicing~~]]	+

OCA at 07:49, 29 June 2022

2022-06-29T07:49:55Z

←Older revision		Revision as of 07:49, 29 June 2022
Line 1:		Line 1:

	==Crystal structure of a Prp8 C-terminal fragment==		==Crystal structure of a Prp8 C-terminal fragment==
-	<StructureSection load='3sbg' size='340' side='right' caption='[[3sbg]], [[Resolution\|resolution]] 3.28Å' scene=''>	+	<StructureSection load='3sbg' size='340' side='right'caption='[[3sbg]], [[Resolution\|resolution]] 3.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3sbg]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3SBG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3sbg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SBG FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3sbs\|3sbs]], [[3sbt\|3sbt]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3sbs\|3sbs]], [[3sbt\|3sbt]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DBF3, DNA39, PRP8, RNA8, SLT21, USA2, YHR165C ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DBF3, DNA39, PRP8, RNA8, SLT21, USA2, YHR165C ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3sbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sbg OCA], [~~http~~://pdbe.org/3sbg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3sbg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3sbg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3sbg ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sbg OCA], [https://pdbe.org/3sbg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sbg RCSB], [https://www.ebi.ac.uk/pdbsum/3sbg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sbg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/PRP8_YEAST PRP8_YEAST]] Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. Also has a role in cell cycle.<ref>PMID:2835658</ref> <ref>PMID:9150140</ref> <ref>PMID:12773561</ref> <ref>PMID:18779563</ref>	+	[[https://www.uniprot.org/uniprot/PRP8_YEAST PRP8_YEAST]] Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. Also has a role in cell cycle.<ref>PMID:2835658</ref> <ref>PMID:9150140</ref> <ref>PMID:12773561</ref> <ref>PMID:18779563</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 21:

	==See Also==		==See Also==
-	*[[Pre-mRNA-splicing ~~factor~~\|Pre-mRNA-splicing ~~factor]]~~	+	*[[Pre-mRNA splicing factors 3D structures\|Pre-mRNA splicing factors 3D structures]]
-	*[[Prp8\|Prp8]]	+
	== References ==		== References ==
	<references/>		<references/>
Line 28:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Baker's yeast]]		[[Category: Baker's yeast]]
		+	[[Category: Large Structures]]
	[[Category: Holton, N]]		[[Category: Holton, N]]
	[[Category: Santos, K]]		[[Category: Santos, K]]

OCA at 07:47, 4 August 2016

2016-08-04T07:47:29Z

←Older revision		Revision as of 07:47, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of a Prp8 C-terminal fragment==		==Crystal structure of a Prp8 C-terminal fragment==
	<StructureSection load='3sbg' size='340' side='right' caption='[[3sbg]], [[Resolution\|resolution]] 3.28Å' scene=''>		<StructureSection load='3sbg' size='340' side='right' caption='[[3sbg]], [[Resolution\|resolution]] 3.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3sbg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae Saccharomyces cerevisiae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SBG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3sbg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SBG FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3sbs\|3sbs]], [[3sbt\|3sbt]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3sbs\|3sbs]], [[3sbt\|3sbt]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DBF3, DNA39, PRP8, RNA8, SLT21, USA2, YHR165C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~4932 Saccharomyces cerevisiae~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DBF3, DNA39, PRP8, RNA8, SLT21, USA2, YHR165C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sbg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sbg RCSB], [http://www.ebi.ac.uk/pdbsum/3sbg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sbg OCA], [http://pdbe.org/3sbg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3sbg RCSB], [http://www.ebi.ac.uk/pdbsum/3sbg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3sbg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3sbg" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 25:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Saccharomyces cerevisiae~~]]	+	[[Category: Baker's yeast]]
	[[Category: Holton, N]]		[[Category: Holton, N]]
	[[Category: Santos, K]]		[[Category: Santos, K]]

OCA at 07:11, 24 December 2014

2014-12-24T07:11:17Z

←Older revision		Revision as of 07:11, 24 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sbg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sbg RCSB], [http://www.ebi.ac.uk/pdbsum/3sbg PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sbg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sbg RCSB], [http://www.ebi.ac.uk/pdbsum/3sbg PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PRP8_YEAST PRP8_YEAST]] Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. Also has a role in cell cycle.<ref>PMID:2835658</ref> <ref>PMID:9150140</ref> <ref>PMID:12773561</ref> <ref>PMID:18779563</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 08:32, 18 December 2014

2014-12-18T08:32:36Z

←Older revision		Revision as of 08:32, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3sbg\| PDB=3sbg \| SCENE= }}~~	+	==Crystal structure of a Prp8 C-terminal fragment==
-	===Crystal structure of a Prp8 C-terminal fragment===	+	<StructureSection load='3sbg' size='340' side='right' caption='[[3sbg]], [[Resolution\|resolution]] 3.28Å' scene=''>
-	~~{{ABSTRACT_PUBMED_21764848}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3sbg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SBG FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3sbs\|3sbs]], [[3sbt\|3sbt]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DBF3, DNA39, PRP8, RNA8, SLT21, USA2, YHR165C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sbg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sbg RCSB], [http://www.ebi.ac.uk/pdbsum/3sbg PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Little is known about how particle-specific proteins are assembled on spliceosomal small nuclear ribonucleoproteins (snRNPs). Brr2p is a U5 snRNP-specific RNA helicase required for spliceosome catalytic activation and disassembly. In yeast, the Aar2 protein is part of a cytoplasmic precursor U5 snRNP that lacks Brr2p and is replaced by Brr2p in the nucleus. Here we show that Aar2p and Brr2p bind to different domains in the C-terminal region of Prp8p; Aar2p interacts with the RNaseH domain, whereas Brr2p interacts with the Jab1/MPN domain. These domains are connected by a long, flexible linker, but the Aar2p-RNaseH complex sequesters the Jab1/MPN domain, thereby preventing binding by Brr2p. Aar2p is phosphorylated in vivo, and a phospho-mimetic S253E mutation in Aar2p leads to disruption of the Aar2p-Prp8p complex in favor of the Brr2p-Prp8p complex. We propose a model in which Aar2p acts as a phosphorylation-controlled U5 snRNP assembly factor that regulates the incorporation of the particle-specific Brr2p. The purpose of this regulation may be to safeguard against nonspecific RNA binding to Prp8p and/or premature activation of Brr2p activity.

-	~~==About this Structure==~~	+	Mechanism for Aar2p function as a U5 snRNP assembly factor.,Weber G, Cristao VF, Alves FD, Santos KF, Holton N, Rappsilber J, Beggs JD, Wahl MC Genes Dev. 2011 Jul 15. PMID:21764848<ref>PMID:21764848</ref>
-	~~[[3sbg]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3SBG OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Pre-mRNA-splicing factor\|Pre-mRNA-splicing factor]]		*[[Pre-mRNA-splicing factor\|Pre-mRNA-splicing factor]]
	*[[Prp8\|Prp8]]		*[[Prp8\|Prp8]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:021764848<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
-	[[Category: Holton, N.]]	+	[[Category: Holton, N]]
-	[[Category: Santos, K.]]	+	[[Category: Santos, K]]
-	[[Category: Wahl, M C.]]	+	[[Category: Wahl, M C]]
-	[[Category: Weber, G.]]	+	[[Category: Weber, G]]
	[[Category: Jab1/mpn domain]]		[[Category: Jab1/mpn domain]]
	[[Category: Prp8p]]		[[Category: Prp8p]]
	[[Category: Rnaseh domain]]		[[Category: Rnaseh domain]]
	[[Category: Splicing]]		[[Category: Splicing]]

OCA at 09:20, 11 March 2013

2013-03-11T09:20:11Z

←Older revision		Revision as of 09:20, 11 March 2013
Line 1:		Line 1:
-	[[Image:3sbg.png\|left\|200px]]
-
	{{STRUCTURE_3sbg\| PDB=3sbg \| SCENE= }}		{{STRUCTURE_3sbg\| PDB=3sbg \| SCENE= }}
-
	===Crystal structure of a Prp8 C-terminal fragment===		===Crystal structure of a Prp8 C-terminal fragment===
-
	{{ABSTRACT_PUBMED_21764848}}		{{ABSTRACT_PUBMED_21764848}}

OCA at 05:21, 20 October 2012

2012-10-20T05:21:54Z

←Older revision		Revision as of 05:21, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3sbg]] is a 1 chain structure ~~of [[Pre-mRNA-splicing factor]]~~ with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBG OCA].	+	[[3sbg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBG OCA].

	==See Also==		==See Also==
	*[[Pre-mRNA-splicing factor\|Pre-mRNA-splicing factor]]		*[[Pre-mRNA-splicing factor\|Pre-mRNA-splicing factor]]
		+	*[[Prp8\|Prp8]]

	==Reference==		==Reference==

OCA at 09:48, 25 July 2012

2012-07-25T09:48:45Z

←Older revision		Revision as of 09:48, 25 July 2012
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-	[[Image:3sbg.~~jpg~~\|left\|200px]]	+	[[Image:3sbg.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_3sbg\| PDB=3sbg \| SCENE= }}		{{STRUCTURE_3sbg\| PDB=3sbg \| SCENE= }}

	===Crystal structure of a Prp8 C-terminal fragment===		===Crystal structure of a Prp8 C-terminal fragment===

-
-	<!--
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	{{ABSTRACT_PUBMED_21764848}}		{{ABSTRACT_PUBMED_21764848}}

	==About this Structure==		==About this Structure==
-	[[3sbg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBG OCA].	+	[[3sbg]] is a 1 chain structure of [[Pre-mRNA-splicing factor]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBG OCA].
		+
		+	==See Also==
		+	*[[Pre-mRNA-splicing factor\|Pre-mRNA-splicing factor]]

	==Reference==		==Reference==

OCA at 07:52, 18 April 2012

2012-04-18T07:52:53Z

←Older revision		Revision as of 07:52, 18 April 2012
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-	~~'''Unreleased structure'''~~	+	[[Image:3sbg.jpg\|left\|200px]]

-	The ~~entry 3sbg~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3sbg", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3sbg\| PDB=3sbg \| SCENE= }}

-	~~Authors: Weber, G., Santos, K., Holton, N., Wahl, M.~~C.	+	===Crystal structure of a Prp8 C-terminal fragment===

-	~~Description~~: ~~Crystal structure of~~ a ~~Prp8 C~~-~~terminal fragment~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21764848}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21764848 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21764848}}
		+
		+	==About this Structure==
		+	[[3sbg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBG OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021764848</ref><references group="xtra"/>
		+	[[Category: Saccharomyces cerevisiae]]
		+	[[Category: Holton, N.]]
		+	[[Category: Santos, K.]]
		+	[[Category: Wahl, M C.]]
		+	[[Category: Weber, G.]]
		+	[[Category: Jab1/mpn domain]]
		+	[[Category: Prp8p]]
		+	[[Category: Rnaseh domain]]
		+	[[Category: Splicing]]

OCA at 05:42, 29 June 2011

2011-06-29T05:42:54Z

←Older revision		Revision as of 05:42, 29 June 2011
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3sbg is ON HOLD	+	The entry 3sbg is ON HOLD until Paper Publication

	Authors: Weber, G., Santos, K., Holton, N., Wahl, M.C.		Authors: Weber, G., Santos, K., Holton, N., Wahl, M.C.

-	Description: Crystal structure of a ~~spliceosomal protein~~ fragment	+	Description: Crystal structure of a Prp8 C-terminal fragment