3sy7 - Revision history

OCA at 09:57, 1 March 2024

2024-03-01T09:57:54Z

←Older revision		Revision as of 09:57, 1 March 2024
Line 3:		Line 3:
	<StructureSection load='3sy7' size='340' side='right'caption='[[3sy7]], [[Resolution\|resolution]] 2.15Å' scene=''>		<StructureSection load='3sy7' size='340' side='right'caption='[[3sy7]], [[Resolution\|resolution]] 2.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3sy7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SY7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SY7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3sy7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SY7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SY7 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.15Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max~~-~~height: 3em;'>[[3sy9\|3sy9]]~~, [[~~3syb~~\|~~3syb]], [[3sys\|3sys]], [[3szd\|3szd]], [[3szv\|3szv]], [[3t0s\|3t0s]], [[3t20\|3t20]], [[2odj\|2odj]], [[3t24\|3t24~~]]~~</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>oprD, PA0958 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~287~~ "~~Bacillus aeruginosus~~" (~~Schroeter 1872~~) ~~Trevisan 1885]~~)</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sy7 OCA], [https://pdbe.org/3sy7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sy7 RCSB], [https://www.ebi.ac.uk/pdbsum/3sy7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sy7 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sy7 OCA], [https://pdbe.org/3sy7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sy7 RCSB], [https://www.ebi.ac.uk/pdbsum/3sy7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sy7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/PORD_PSEAE PORD_PSEAE]] Porin with a specificity for basic amino acids. Also possesses serine protease activity.<ref>PMID:2118530</ref> <ref>PMID:8843159</ref>	+	[https://www.uniprot.org/uniprot/PORD_PSEAE PORD_PSEAE] Porin with a specificity for basic amino acids. Also possesses serine protease activity.<ref>PMID:2118530</ref> <ref>PMID:8843159</ref>
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	Many Gram-negative bacteria, including human pathogens such as Pseudomonas aeruginosa, do not have large-channel porins. This results in an outer membrane (OM) that is highly impermeable to small polar molecules, making the bacteria intrinsically resistant towards many antibiotics. In such microorganisms, the majority of small molecules are taken up by members of the OprD outer membrane protein family. Here we show that OprD channels require a carboxyl group in the substrate for efficient transport, and based on this we have renamed the family Occ, for outer membrane carboxylate channels. We further show that Occ channels can be divided into two subfamilies, based on their very different substrate specificities. Our results rationalize how certain bacteria can efficiently take up a variety of substrates under nutrient-poor conditions without compromising membrane permeability. In addition, they explain how channel inactivation in response to antibiotics can cause resistance but does not lead to decreased fitness.	+
-		+
-	Substrate Specificity within a Family of Outer Membrane Carboxylate Channels.,Eren E, Vijayaraghavan J, Liu J, Cheneke BR, Touw DS, Lepore BW, Indic M, Movileanu L, van den Berg B PLoS Biol. 2012 Jan;10(1):e1001242. Epub 2012 Jan 17. PMID:22272184<ref>PMID:22272184</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 3sy7" style="background-color:#fffaf0;"></div~~>	+

	==See Also==		==See Also==
Line 28:		Line 18:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Berg, B van den~~]]	+	[[Category: Pseudomonas aeruginosa]]
-	[[Category: Eren, E]]	+	[[Category: Eren E]]
-	[[Category: ~~Beta-barrel]]~~	+	[[Category: Van den Berg B]]
-	~~[[Category: Channel]]~~	+
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Outer membrane~~]]	+

OCA at 08:15, 29 June 2022

2022-06-29T08:15:49Z

←Older revision		Revision as of 08:15, 29 June 2022
Line 1:		Line 1:

	==Improved crystal structure of Pseudomonas aeruginosa OprD==		==Improved crystal structure of Pseudomonas aeruginosa OprD==
-	<StructureSection load='3sy7' size='340' side='right' caption='[[3sy7]], [[Resolution\|resolution]] 2.15Å' scene=''>	+	<StructureSection load='3sy7' size='340' side='right'caption='[[3sy7]], [[Resolution\|resolution]] 2.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3sy7]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SY7 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3SY7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3sy7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SY7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SY7 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3sy9\|3sy9]], [[3syb\|3syb]], [[3sys\|3sys]], [[3szd\|3szd]], [[3szv\|3szv]], [[3t0s\|3t0s]], [[3t20\|3t20]], [[2odj\|2odj]], [[3t24\|3t24]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3sy9\|3sy9]], [[3syb\|3syb]], [[3sys\|3sys]], [[3szd\|3szd]], [[3szv\|3szv]], [[3t0s\|3t0s]], [[3t20\|3t20]], [[2odj\|2odj]], [[3t24\|3t24]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oprD, PA0958 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oprD, PA0958 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3sy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sy7 OCA], [~~http~~://pdbe.org/3sy7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3sy7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3sy7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3sy7 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sy7 OCA], [https://pdbe.org/3sy7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sy7 RCSB], [https://www.ebi.ac.uk/pdbsum/3sy7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sy7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/PORD_PSEAE PORD_PSEAE]] Porin with a specificity for basic amino acids. Also possesses serine protease activity.<ref>PMID:2118530</ref> <ref>PMID:8843159</ref>	+	[[https://www.uniprot.org/uniprot/PORD_PSEAE PORD_PSEAE]] Porin with a specificity for basic amino acids. Also possesses serine protease activity.<ref>PMID:2118530</ref> <ref>PMID:8843159</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:

	==See Also==		==See Also==
-	*[[Porin\|Porin]]	+	*[[Porin 3D structures\|Porin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Berg, B van den]]		[[Category: Berg, B van den]]
	[[Category: Eren, E]]		[[Category: Eren, E]]

OCA at 23:21, 4 August 2016

2016-08-04T23:21:20Z

←Older revision		Revision as of 23:21, 4 August 2016
Line 1:		Line 1:
		+
	==Improved crystal structure of Pseudomonas aeruginosa OprD==		==Improved crystal structure of Pseudomonas aeruginosa OprD==
	<StructureSection load='3sy7' size='340' side='right' caption='[[3sy7]], [[Resolution\|resolution]] 2.15Å' scene=''>		<StructureSection load='3sy7' size='340' side='right' caption='[[3sy7]], [[Resolution\|resolution]] 2.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3sy7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pseudomonas_aeruginosa Pseudomonas aeruginosa~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SY7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SY7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3sy7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SY7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SY7 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3sy9\|3sy9]], [[3syb\|3syb]], [[3sys\|3sys]], [[3szd\|3szd]], [[3szv\|3szv]], [[3t0s\|3t0s]], [[3t20\|3t20]], [[2odj\|2odj]], [[3t24\|3t24]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3sy9\|3sy9]], [[3syb\|3syb]], [[3sys\|3sys]], [[3szd\|3szd]], [[3szv\|3szv]], [[3t0s\|3t0s]], [[3t20\|3t20]], [[2odj\|2odj]], [[3t24\|3t24]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oprD, PA0958 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 ~~Pseudomonas aeruginosa~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oprD, PA0958 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sy7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sy7 RCSB], [http://www.ebi.ac.uk/pdbsum/3sy7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sy7 OCA], [http://pdbe.org/3sy7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3sy7 RCSB], [http://www.ebi.ac.uk/pdbsum/3sy7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3sy7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3sy7" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 25:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Pseudomonas aeruginosa]]
	[[Category: Berg, B van den]]		[[Category: Berg, B van den]]
	[[Category: Eren, E]]		[[Category: Eren, E]]

OCA at 13:57, 25 December 2014

2014-12-25T13:57:20Z

←Older revision		Revision as of 13:57, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sy7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sy7 RCSB], [http://www.ebi.ac.uk/pdbsum/3sy7 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sy7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sy7 RCSB], [http://www.ebi.ac.uk/pdbsum/3sy7 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PORD_PSEAE PORD_PSEAE]] Porin with a specificity for basic amino acids. Also possesses serine protease activity.<ref>PMID:2118530</ref> <ref>PMID:8843159</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 13:15, 9 December 2014

2014-12-09T13:15:50Z

←Older revision		Revision as of 13:15, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3sy7.~~png~~\|~~left~~\|~~200px~~]]	+	==Improved crystal structure of Pseudomonas aeruginosa OprD==
		+	<StructureSection load='3sy7' size='340' side='right' caption='[[3sy7]], [[Resolution\|resolution]] 2.15Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3sy7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SY7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SY7 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3sy9\|3sy9]], [[3syb\|3syb]], [[3sys\|3sys]], [[3szd\|3szd]], [[3szv\|3szv]], [[3t0s\|3t0s]], [[3t20\|3t20]], [[2odj\|2odj]], [[3t24\|3t24]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oprD, PA0958 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sy7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sy7 RCSB], [http://www.ebi.ac.uk/pdbsum/3sy7 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Many Gram-negative bacteria, including human pathogens such as Pseudomonas aeruginosa, do not have large-channel porins. This results in an outer membrane (OM) that is highly impermeable to small polar molecules, making the bacteria intrinsically resistant towards many antibiotics. In such microorganisms, the majority of small molecules are taken up by members of the OprD outer membrane protein family. Here we show that OprD channels require a carboxyl group in the substrate for efficient transport, and based on this we have renamed the family Occ, for outer membrane carboxylate channels. We further show that Occ channels can be divided into two subfamilies, based on their very different substrate specificities. Our results rationalize how certain bacteria can efficiently take up a variety of substrates under nutrient-poor conditions without compromising membrane permeability. In addition, they explain how channel inactivation in response to antibiotics can cause resistance but does not lead to decreased fitness.

-	~~{{STRUCTURE_3sy7\| PDB=3sy7 \| SCENE= }}~~	+	Substrate Specificity within a Family of Outer Membrane Carboxylate Channels.,Eren E, Vijayaraghavan J, Liu J, Cheneke BR, Touw DS, Lepore BW, Indic M, Movileanu L, van den Berg B PLoS Biol. 2012 Jan;10(1):e1001242. Epub 2012 Jan 17. PMID:22272184<ref>PMID:22272184</ref>

-	~~===Improved crystal structure~~ of ~~Pseudomonas aeruginosa OprD===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22272184}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3sy7]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3SY7 OCA].~~	+

	==See Also==		==See Also==
	*[[Porin\|Porin]]		*[[Porin\|Porin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:022272184<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Pseudomonas aeruginosa]]		[[Category: Pseudomonas aeruginosa]]
-	[[Category: Berg, B van den.]]	+	[[Category: Berg, B van den]]
-	[[Category: Eren, E.]]	+	[[Category: Eren, E]]
	[[Category: Beta-barrel]]		[[Category: Beta-barrel]]
	[[Category: Channel]]		[[Category: Channel]]
	[[Category: Membrane protein]]		[[Category: Membrane protein]]
	[[Category: Outer membrane]]		[[Category: Outer membrane]]

OCA at 17:31, 20 October 2012

2012-10-20T17:31:33Z

←Older revision		Revision as of 17:31, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3sy7]] is a 1 chain structure ~~of [[Porin]]~~ with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SY7 OCA].	+	[[3sy7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SY7 OCA].

	==See Also==		==See Also==

OCA at 01:10, 27 July 2012

2012-07-27T01:10:35Z

←Older revision		Revision as of 01:10, 27 July 2012
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-	[[Image:3sy7.~~jpg~~\|left\|200px]]	+	[[Image:3sy7.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_3sy7\| PDB=3sy7 \| SCENE= }}		{{STRUCTURE_3sy7\| PDB=3sy7 \| SCENE= }}

	===Improved crystal structure of Pseudomonas aeruginosa OprD===		===Improved crystal structure of Pseudomonas aeruginosa OprD===

-
-	<!--
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	{{ABSTRACT_PUBMED_22272184}}		{{ABSTRACT_PUBMED_22272184}}

	==About this Structure==		==About this Structure==
-	[[3sy7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SY7 OCA].	+	[[3sy7]] is a 1 chain structure of [[Porin]] with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SY7 OCA].
		+
		+	==See Also==
		+	*[[Porin\|Porin]]

	==Reference==		==Reference==

OCA at 06:27, 8 February 2012

2012-02-08T06:27:56Z

←Older revision		Revision as of 06:27, 8 February 2012
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-	~~'''Unreleased structure'''~~	+	[[Image:3sy7.jpg\|left\|200px]]

-	The ~~entry 3sy7~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3sy7", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3sy7\| PDB=3sy7 \| SCENE= }}

-	~~Authors: van den Berg, B., Eren, E.~~	+	===Improved crystal structure of Pseudomonas aeruginosa OprD===

-	~~Description~~: ~~Improved crystal~~ structure of Pseudomonas aeruginosa ~~OprD~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22272184}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22272184 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22272184}}
		+
		+	==About this Structure==
		+	[[3sy7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SY7 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022272184</ref><references group="xtra"/>
		+	[[Category: Pseudomonas aeruginosa]]
		+	[[Category: Berg, B van den.]]
		+	[[Category: Eren, E.]]
		+	[[Category: Beta-barrel]]
		+	[[Category: Channel]]
		+	[[Category: Membrane protein]]
		+	[[Category: Outer membrane]]

OCA at 05:43, 7 September 2011

2011-09-07T05:43:41Z

←Older revision		Revision as of 05:43, 7 September 2011
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3sy7 is ON HOLD	+	The entry 3sy7 is ON HOLD until Paper Publication

	Authors: van den Berg, B., Eren, E.		Authors: van den Berg, B., Eren, E.

	Description: Improved crystal structure of Pseudomonas aeruginosa OprD		Description: Improved crystal structure of Pseudomonas aeruginosa OprD

OCA: Protected "3sy7" [edit=sysop:move=sysop]

2011-07-27T05:44:08Z

Protected "3sy7" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:44, 27 July 2011