3t4m - Revision history

OCA at 06:44, 3 April 2024

2024-04-03T06:44:59Z

←Older revision		Revision as of 06:44, 3 April 2024
Line 3:		Line 3:
	<StructureSection load='3t4m' size='340' side='right'caption='[[3t4m]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='3t4m' size='340' side='right'caption='[[3t4m]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3t4m]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Aplca Aplca~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T4M FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3t4m]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T4M FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2byn\|2byn]], [[2y7y\|2y7y]], [[3sh1\|3sh1]], [[3sio\|3sio]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AChBP ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6500 APLCA])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4m OCA], [https://pdbe.org/3t4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t4m RCSB], [https://www.ebi.ac.uk/pdbsum/3t4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t4m ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4m OCA], [https://pdbe.org/3t4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t4m RCSB], [https://www.ebi.ac.uk/pdbsum/3t4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t4m ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/Q8WSF8_APLCA Q8WSF8_APLCA]
-	Determining the structure of the ligand-binding domain of the nicotinic acetylcholine receptor (nAChR) has been a long standing goal in the design of selective drugs useful in implicated diseases for this prevalent receptor family. Acetylcholine-binding proteins have proven to be valuable surrogates with structural similarity and sequence identity to the extracellular domain of the nicotinic receptor, yet these soluble proteins have their unique features and do not serve as exact replicates of the nAChRs of interest. Here we systematically modify the sequence of these proteins toward the homomeric human alpha7 nAChR. These chimeric proteins exhibit a shift in affinities to reflect alpha7 binding characteristics yet maintain expression levels and stability conducive for crystallization. We also present a pentameric humanoid nAChR extracellular domain with the structural determination of the alpha7 nAChR glycosylation site.	+
-		+
-	~~Creating an alpha7 nicotinic acetylcholine recognition domain from the acetylcholine-binding protein~~: ~~crystallographic and ligand selectivity analyses.,Nemecz A, Taylor P J Biol Chem. 2011 Dec 9;286(49):42555-65. Epub 2011 Oct 18. PMID:22009746<ref>PMID:22009746<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®~~/~~PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 3t4m" style="background-color:#fffaf0;"><~~/~~div>~~	+

	==See Also==		==See Also==
	*[[Acetylcholine binding protein 3D structures\|Acetylcholine binding protein 3D structures]]		*[[Acetylcholine binding protein 3D structures\|Acetylcholine binding protein 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Aplca~~]]	+	[[Category: Aplysia californica]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Nemecz, A]]	+	[[Category: Nemecz A]]
-	[[Category: Taylor~~, P W]]~~	+	[[Category: Taylor PW]]
-	~~[[Category: Acetylcholine]]~~	+
-	~~[[Category: Achbp]]~~	+
-	~~[[Category: Alpha-7 human nicotinic acetylcholine receptor]]~~	+
-	~~[[Category: Aplysia californica]]~~	+
-	~~[[Category: Binding protein]]~~	+
-	~~[[Category: Glycosylation]]~~	+
-	~~[[Category: Mutated acetylcholine binding protein]]~~	+
-	~~[[Category: Nachr]]~~	+
-	~~[[Category: Receptor~~]]	+

OCA at 16:42, 6 July 2022

2022-07-06T16:42:46Z

←Older revision		Revision as of 16:42, 6 July 2022
Line 1:		Line 1:

	==Ac-AChBP ligand binding domain mutated to human alpha-7 nAChR (intermediate)==		==Ac-AChBP ligand binding domain mutated to human alpha-7 nAChR (intermediate)==
-	<StructureSection load='3t4m' size='340' side='right' caption='[[3t4m]], [[Resolution\|resolution]] 3.00Å' scene=''>	+	<StructureSection load='3t4m' size='340' side='right'caption='[[3t4m]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3t4m]] is a 10 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Aplca Aplca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4M OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3T4M FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3t4m]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Aplca Aplca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T4M FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2byn\|2byn]], [[2y7y\|2y7y]], [[3sh1\|3sh1]], [[3sio\|3sio]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2byn\|2byn]], [[2y7y\|2y7y]], [[3sh1\|3sh1]], [[3sio\|3sio]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AChBP ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6500 APLCA])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AChBP ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6500 APLCA])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3t4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4m OCA], [~~http~~://pdbe.org/3t4m PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3t4m RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3t4m PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3t4m ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4m OCA], [https://pdbe.org/3t4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t4m RCSB], [https://www.ebi.ac.uk/pdbsum/3t4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t4m ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 3t4m" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3t4m" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Acetylcholine binding protein 3D structures\|Acetylcholine binding protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 23:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Aplca]]		[[Category: Aplca]]
		+	[[Category: Large Structures]]
	[[Category: Nemecz, A]]		[[Category: Nemecz, A]]
	[[Category: Taylor, P W]]		[[Category: Taylor, P W]]

OCA at 09:48, 8 November 2017

2017-11-08T09:48:05Z

←Older revision		Revision as of 09:48, 8 November 2017
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 3t4m" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3t4m" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Acetylcholine binding protein\|Acetylcholine binding protein]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:02, 5 August 2016

2016-08-05T07:02:24Z

←Older revision		Revision as of 07:02, 5 August 2016
Line 1:		Line 1:
		+
	==Ac-AChBP ligand binding domain mutated to human alpha-7 nAChR (intermediate)==		==Ac-AChBP ligand binding domain mutated to human alpha-7 nAChR (intermediate)==
	<StructureSection load='3t4m' size='340' side='right' caption='[[3t4m]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='3t4m' size='340' side='right' caption='[[3t4m]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3t4m]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Aplysia_californica Aplysia californica~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T4M FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3t4m]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplca Aplca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T4M FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2byn\|2byn]], [[2y7y\|2y7y]], [[3sh1\|3sh1]], [[3sio\|3sio]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2byn\|2byn]], [[2y7y\|2y7y]], [[3sh1\|3sh1]], [[3sio\|3sio]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AChBP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6500 ~~Aplysia californica~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AChBP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6500 APLCA])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t4m RCSB], [http://www.ebi.ac.uk/pdbsum/3t4m PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4m OCA], [http://pdbe.org/3t4m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3t4m RCSB], [http://www.ebi.ac.uk/pdbsum/3t4m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3t4m ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3t4m" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 23:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Aplysia californica~~]]	+	[[Category: Aplca]]
	[[Category: Nemecz, A]]		[[Category: Nemecz, A]]
	[[Category: Taylor, P W]]		[[Category: Taylor, P W]]
Line 29:		Line 31:
	[[Category: Achbp]]		[[Category: Achbp]]
	[[Category: Alpha-7 human nicotinic acetylcholine receptor]]		[[Category: Alpha-7 human nicotinic acetylcholine receptor]]
		+	[[Category: Aplysia californica]]
	[[Category: Binding protein]]		[[Category: Binding protein]]
	[[Category: Glycosylation]]		[[Category: Glycosylation]]

OCA at 06:54, 21 December 2014

2014-12-21T06:54:42Z

←Older revision		Revision as of 06:54, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3t4m\| PDB=3t4m \| SCENE= }}~~	+	==Ac-AChBP ligand binding domain mutated to human alpha-7 nAChR (intermediate)==
-	===Ac-AChBP ligand binding domain mutated to human alpha-7 nAChR (intermediate)===	+	<StructureSection load='3t4m' size='340' side='right' caption='[[3t4m]], [[Resolution\|resolution]] 3.00Å' scene=''>
-	~~{{ABSTRACT_PUBMED_22009746}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3t4m]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T4M FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2byn\|2byn]], [[2y7y\|2y7y]], [[3sh1\|3sh1]], [[3sio\|3sio]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AChBP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6500 Aplysia californica])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t4m RCSB], [http://www.ebi.ac.uk/pdbsum/3t4m PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Determining the structure of the ligand-binding domain of the nicotinic acetylcholine receptor (nAChR) has been a long standing goal in the design of selective drugs useful in implicated diseases for this prevalent receptor family. Acetylcholine-binding proteins have proven to be valuable surrogates with structural similarity and sequence identity to the extracellular domain of the nicotinic receptor, yet these soluble proteins have their unique features and do not serve as exact replicates of the nAChRs of interest. Here we systematically modify the sequence of these proteins toward the homomeric human alpha7 nAChR. These chimeric proteins exhibit a shift in affinities to reflect alpha7 binding characteristics yet maintain expression levels and stability conducive for crystallization. We also present a pentameric humanoid nAChR extracellular domain with the structural determination of the alpha7 nAChR glycosylation site.

-	~~==About this Structure==~~	+	Creating an alpha7 nicotinic acetylcholine recognition domain from the acetylcholine-binding protein: crystallographic and ligand selectivity analyses.,Nemecz A, Taylor P J Biol Chem. 2011 Dec 9;286(49):42555-65. Epub 2011 Oct 18. PMID:22009746<ref>PMID:22009746</ref>
-	~~[[3t4m]] is a 10 chain structure with sequence~~ from ~~[http~~:~~//en~~.~~wikipedia~~.~~org/wiki/Aplysia_californica Aplysia californica]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3T4M OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Acetylcholine binding protein\|Acetylcholine binding protein]]		*[[Acetylcholine binding protein\|Acetylcholine binding protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:022009746</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Aplysia californica]]		[[Category: Aplysia californica]]
-	[[Category: Nemecz, A.]]	+	[[Category: Nemecz, A]]
-	[[Category: Taylor, P W.]]	+	[[Category: Taylor, P W]]
	[[Category: Acetylcholine]]		[[Category: Acetylcholine]]
	[[Category: Achbp]]		[[Category: Achbp]]
	[[Category: Alpha-7 human nicotinic acetylcholine receptor]]		[[Category: Alpha-7 human nicotinic acetylcholine receptor]]
-	[[Category: Aplysia californica]]
	[[Category: Binding protein]]		[[Category: Binding protein]]
	[[Category: Glycosylation]]		[[Category: Glycosylation]]

OCA at 04:31, 18 July 2013

2013-07-18T04:31:34Z

←Older revision		Revision as of 04:31, 18 July 2013
Line 1:		Line 1:
-	[[Image:3t4m.png\|left\|200px]]
-
	{{STRUCTURE_3t4m\| PDB=3t4m \| SCENE= }}		{{STRUCTURE_3t4m\| PDB=3t4m \| SCENE= }}
-
	===Ac-AChBP ligand binding domain mutated to human alpha-7 nAChR (intermediate)===		===Ac-AChBP ligand binding domain mutated to human alpha-7 nAChR (intermediate)===
-		+	{{ABSTRACT_PUBMED_22009746}}

	==About this Structure==		==About this Structure==
Line 11:		Line 8:
	==See Also==		==See Also==
	*[[Acetylcholine binding protein\|Acetylcholine binding protein]]		*[[Acetylcholine binding protein\|Acetylcholine binding protein]]
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022009746</ref><references group="xtra"/><references/>
	[[Category: Aplysia californica]]		[[Category: Aplysia californica]]
	[[Category: Nemecz, A.]]		[[Category: Nemecz, A.]]

OCA at 10:29, 20 October 2012

2012-10-20T10:29:04Z

←Older revision		Revision as of 10:29, 20 October 2012
Line 7:		Line 7:

	==About this Structure==		==About this Structure==
-	[[3t4m]] is a 10 chain structure ~~of [[Acetylcholine binding protein]]~~ with sequence from [http://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4M OCA].	+	[[3t4m]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4M OCA].

	==See Also==		==See Also==

OCA at 02:16, 26 July 2012

2012-07-26T02:16:22Z

←Older revision		Revision as of 02:16, 26 July 2012
Line 1:		Line 1:
	[[Image:3t4m.png\|left\|200px]]		[[Image:3t4m.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3t4m", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3t4m\| PDB=3t4m \| SCENE= }}		{{STRUCTURE_3t4m\| PDB=3t4m \| SCENE= }}

Line 13:		Line 7:

	==About this Structure==		==About this Structure==
-	[[3t4m]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4M OCA].	+	[[3t4m]] is a 10 chain structure of [[Acetylcholine binding protein]] with sequence from [http://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4M OCA].
		+
		+	==See Also==
		+	*[[Acetylcholine binding protein\|Acetylcholine binding protein]]
	[[Category: Aplysia californica]]		[[Category: Aplysia californica]]
	[[Category: Nemecz, A.]]		[[Category: Nemecz, A.]]

OCA at 11:25, 30 October 2011

2011-10-30T11:25:47Z

←Older revision		Revision as of 11:25, 30 October 2011
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-	~~'''Unreleased structure'''~~	+	[[Image:3t4m.png\|left\|200px]]

-	The ~~entry 3t4m~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3t4m", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3t4m\| PDB=3t4m \| SCENE= }}

-	~~Authors: Nemecz, A., Taylor, P.W.~~	+	===Ac-AChBP ligand binding domain mutated to human alpha-7 nAChR (intermediate)===

-	~~Description~~: Ac-~~AChBP ligand binding domain mutated to human alpha~~-7 ~~nAChR (intermediate)~~	+
		+	==About this Structure==
		+	[[3t4m]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4M OCA].
		+	[[Category: Aplysia californica]]
		+	[[Category: Nemecz, A.]]
		+	[[Category: Taylor, P W.]]
		+	[[Category: Acetylcholine]]
		+	[[Category: Achbp]]
		+	[[Category: Alpha-7 human nicotinic acetylcholine receptor]]
		+	[[Category: Aplysia californica]]
		+	[[Category: Binding protein]]
		+	[[Category: Glycosylation]]
		+	[[Category: Mutated acetylcholine binding protein]]
		+	[[Category: Nachr]]
		+	[[Category: Receptor]]

OCA at 05:44, 7 September 2011

2011-09-07T05:44:55Z

←Older revision		Revision as of 05:44, 7 September 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3t4m is ON HOLD	+	The entry 3t4m is ON HOLD until Paper Publication

	Authors: Nemecz, A., Taylor, P.W.		Authors: Nemecz, A., Taylor, P.W.

	Description: Ac-AChBP ligand binding domain mutated to human alpha-7 nAChR (intermediate)		Description: Ac-AChBP ligand binding domain mutated to human alpha-7 nAChR (intermediate)