3tsg - Revision history

OCA at 13:38, 14 March 2024

2024-03-14T13:38:07Z

←Older revision		Revision as of 13:38, 14 March 2024
Line 3:		Line 3:
	<StructureSection load='3tsg' size='340' side='right'caption='[[3tsg]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='3tsg' size='340' side='right'caption='[[3tsg]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3tsg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Aciba Aciba~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TSG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3tsg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Acinetobacter_baumannii Acinetobacter baumannii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TSG FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~, ~~<scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[2qpn\|2qpn]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>blaGES-14 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~470 ACIBA])</td~~><~~/tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tsg OCA], [https://pdbe.org/3tsg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tsg RCSB], [https://www.ebi.ac.uk/pdbsum/3tsg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tsg ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tsg OCA], [https://pdbe.org/3tsg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tsg RCSB], [https://www.ebi.ac.uk/pdbsum/3tsg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tsg ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/D3X610_ACIBA D3X610_ACIBA]
-	GES-1 is a class A extended-spectrum beta-lactamase conferring resistance to penicillins, first-, second-generation cephalosporins and to ceftazidime. However, GES-1 poorly hydrolyzes aztreonam and cephamycins, and exhibits very low k(cat) values for carbapenems. Twenty-two GES variants have been discovered thus far, differing from each other by 1-3 amino acid substitutions that affect substrate specificity. GES-11 possesses a Gly243Ala substitution which seems to confer this variant an increased activity against aztreonam and ceftazidime. GES-12 differs from GES-11 by a single Thr237Ala substitution while GES-14 differs from GES-11 by the Gly170Ser mutation which is known to confer increased carbapenemase activity. GES-11 and GES-12 were kinetically characterized and compared with GES-1 and GES-14. Purified GES-11 and GES-12 showed strong activities against most tested beta-lactams with the exception of temocillin, cefoxitin and carbapenems. Both variants showed a significantly increased rate of hydrolysis of cefotaxime, ceftazidime and aztreonam. On the other hand, GES-11, GES-12 (and GES-14) variants all containing Ala243 exhibited increased susceptibility to classical inhibitors. The crystallographic structures of the GES-11 and GES-14 beta-lactamases were solved. The overall structures of GES-11 and GES-14 are similar to that of GES-1. The Gly243Ala substitution caused only subtle local rearrangements, notably in the typical carbapenemase disulfide bond. The active sites of GES-14 and GES-11 are very similar, the Gly170Ser substitution leading only to the formation of additional hydrogen bonds of the Ser residue with the hydrolytic water and the Glu166 residue.	+
-		+
-	Kinetic and crystallographic studies of extended spectrum GES-11, GES-12 and GES-14 beta-lactamases.,Delbruck H, Bogaerts P, Kupper MB, de Castro RR, Bennink S, Glupczynski Y, Galleni M, Hoffmann KM, Bebrone C Antimicrob Agents Chemother. 2012 Aug 20. PMID:~~22908160<ref>PMID:22908160<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®~~/~~PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 3tsg" style="background-color:#fffaf0;"><~~/~~div>~~	+

	==See Also==		==See Also==
	*[[Beta-lactamase 3D structures\|Beta-lactamase 3D structures]]		*[[Beta-lactamase 3D structures\|Beta-lactamase 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Aciba]]~~	+	[[Category: Acinetobacter baumannii]]
-	~~[[Category: Beta-lactamase~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bebrone, C]]	+	[[Category: Bebrone C]]
-	[[Category: Delbruck, H]]	+	[[Category: Delbruck H]]
-	[[Category: Hoffmann~~, K M.V]]~~	+	[[Category: Hoffmann KMV]]
-	~~[[Category: Beta lactamase fold]]~~	+
-	~~[[Category: Beta lactam]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 05:43, 13 July 2022

2022-07-13T05:43:21Z

←Older revision		Revision as of 05:43, 13 July 2022
Line 1:		Line 1:

	==Crystal structure of GES-14==		==Crystal structure of GES-14==
-	<StructureSection load='3tsg' size='340' side='right' caption='[[3tsg]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='3tsg' size='340' side='right'caption='[[3tsg]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3tsg]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Aciba Aciba]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3TSG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3tsg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aciba Aciba]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TSG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2qpn\|2qpn]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2qpn\|2qpn]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaGES-14 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=470 ACIBA])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaGES-14 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=470 ACIBA])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3tsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tsg OCA], [~~http~~://pdbe.org/3tsg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3tsg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3tsg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3tsg ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tsg OCA], [https://pdbe.org/3tsg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tsg RCSB], [https://www.ebi.ac.uk/pdbsum/3tsg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tsg ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 21:		Line 21:

	==See Also==		==See Also==
-	*[[Beta-lactamase\|Beta-lactamase]]	+	*[[Beta-lactamase 3D structures\|Beta-lactamase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 28:		Line 28:
	[[Category: Aciba]]		[[Category: Aciba]]
	[[Category: Beta-lactamase]]		[[Category: Beta-lactamase]]
		+	[[Category: Large Structures]]
	[[Category: Bebrone, C]]		[[Category: Bebrone, C]]
	[[Category: Delbruck, H]]		[[Category: Delbruck, H]]

OCA at 07:43, 4 August 2016

2016-08-04T07:43:18Z

←Older revision		Revision as of 07:43, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of GES-14==		==Crystal structure of GES-14==
	<StructureSection load='3tsg' size='340' side='right' caption='[[3tsg]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='3tsg' size='340' side='right' caption='[[3tsg]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3tsg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Acinetobacter_baumannii Acinetobacter baumannii~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TSG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3tsg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aciba Aciba]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TSG FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2qpn\|2qpn]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2qpn\|2qpn]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaGES-14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=470 ~~Acinetobacter baumannii~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaGES-14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=470 ACIBA])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tsg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tsg RCSB], [http://www.ebi.ac.uk/pdbsum/3tsg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tsg OCA], [http://pdbe.org/3tsg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3tsg RCSB], [http://www.ebi.ac.uk/pdbsum/3tsg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3tsg ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3tsg" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 24:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Acinetobacter baumannii~~]]	+	[[Category: Aciba]]
	[[Category: Beta-lactamase]]		[[Category: Beta-lactamase]]
	[[Category: Bebrone, C]]		[[Category: Bebrone, C]]

OCA at 06:59, 21 December 2014

2014-12-21T06:59:53Z

←Older revision		Revision as of 06:59, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3tsg\| PDB~~=3tsg \| ~~SCENE~~= }}	+	==Crystal structure of GES-14==
-	===~~Crystal~~ structure ~~of GES~~-14===	+	<StructureSection load='3tsg' size='340' side='right' caption='[[3tsg]], [[Resolution\|resolution]] 1.90Å' scene=''>
-	~~{{ABSTRACT_PUBMED_22908160}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3tsg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Acinetobacter_baumannii Acinetobacter baumannii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TSG FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2qpn\|2qpn]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaGES-14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=470 Acinetobacter baumannii])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tsg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tsg RCSB], [http://www.ebi.ac.uk/pdbsum/3tsg PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	GES-1 is a class A extended-spectrum beta-lactamase conferring resistance to penicillins, first-, second-generation cephalosporins and to ceftazidime. However, GES-1 poorly hydrolyzes aztreonam and cephamycins, and exhibits very low k(cat) values for carbapenems. Twenty-two GES variants have been discovered thus far, differing from each other by 1-3 amino acid substitutions that affect substrate specificity. GES-11 possesses a Gly243Ala substitution which seems to confer this variant an increased activity against aztreonam and ceftazidime. GES-12 differs from GES-11 by a single Thr237Ala substitution while GES-14 differs from GES-11 by the Gly170Ser mutation which is known to confer increased carbapenemase activity. GES-11 and GES-12 were kinetically characterized and compared with GES-1 and GES-14. Purified GES-11 and GES-12 showed strong activities against most tested beta-lactams with the exception of temocillin, cefoxitin and carbapenems. Both variants showed a significantly increased rate of hydrolysis of cefotaxime, ceftazidime and aztreonam. On the other hand, GES-11, GES-12 (and GES-14) variants all containing Ala243 exhibited increased susceptibility to classical inhibitors. The crystallographic structures of the GES-11 and GES-14 beta-lactamases were solved. The overall structures of GES-11 and GES-14 are similar to that of GES-1. The Gly243Ala substitution caused only subtle local rearrangements, notably in the typical carbapenemase disulfide bond. The active sites of GES-14 and GES-11 are very similar, the Gly170Ser substitution leading only to the formation of additional hydrogen bonds of the Ser residue with the hydrolytic water and the Glu166 residue.

-	~~==About this Structure==~~	+	Kinetic and crystallographic studies of extended spectrum GES-11, GES-12 and GES-14 beta-lactamases.,Delbruck H, Bogaerts P, Kupper MB, de Castro RR, Bennink S, Glupczynski Y, Galleni M, Hoffmann KM, Bebrone C Antimicrob Agents Chemother. 2012 Aug 20. PMID:22908160<ref>PMID:22908160</ref>
-	~~[[3tsg]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Acinetobacter_baumannii Acinetobacter baumannii]~~. ~~Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3TSG OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group~~=~~"xtra">PMID:022908160</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+
		+	==See Also==
		+	*[[Beta-lactamase\|Beta-lactamase]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Acinetobacter baumannii]]		[[Category: Acinetobacter baumannii]]
	[[Category: Beta-lactamase]]		[[Category: Beta-lactamase]]
-	[[Category: Bebrone, C.]]	+	[[Category: Bebrone, C]]
-	[[Category: Delbruck, H.]]	+	[[Category: Delbruck, H]]
-	[[Category: Hoffmann, K M.V.]]	+	[[Category: Hoffmann, K M.V]]
	[[Category: Beta lactamase fold]]		[[Category: Beta lactamase fold]]
	[[Category: Beta lactam]]		[[Category: Beta lactam]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 07:40, 20 June 2013

2013-06-20T07:40:24Z

←Older revision		Revision as of 07:40, 20 June 2013
Line 1:		Line 1:
-	[[Image:3tsg.jpg\|left\|200px]]
-
	{{STRUCTURE_3tsg\| PDB=3tsg \| SCENE= }}		{{STRUCTURE_3tsg\| PDB=3tsg \| SCENE= }}
-
	===Crystal structure of GES-14===		===Crystal structure of GES-14===
-
	{{ABSTRACT_PUBMED_22908160}}		{{ABSTRACT_PUBMED_22908160}}

	==About this Structure==		==About this Structure==
	[[3tsg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Acinetobacter_baumannii Acinetobacter baumannii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSG OCA].		[[3tsg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Acinetobacter_baumannii Acinetobacter baumannii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSG OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022908160</ref><references group="xtra"/><references/>
	[[Category: Acinetobacter baumannii]]		[[Category: Acinetobacter baumannii]]
	[[Category: Beta-lactamase]]		[[Category: Beta-lactamase]]

OCA at 20:37, 26 September 2012

2012-09-26T20:37:08Z

←Older revision		Revision as of 20:37, 26 September 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3tsg.jpg\|left\|200px]]

-	~~The entry~~ 3tsg ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_3tsg\| PDB=3tsg \| SCENE= }}

-	~~Authors: Delbruck, H., Hoffmann, K.M.V., Bebrone, C.~~	+	===Crystal structure of GES-14===

-	~~Description: Crystal~~ structure ~~of GES~~-14	+	{{ABSTRACT_PUBMED_22908160}}
		+
		+	==About this Structure==
		+	[[3tsg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Acinetobacter_baumannii Acinetobacter baumannii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSG OCA].
		+	[[Category: Acinetobacter baumannii]]
		+	[[Category: Beta-lactamase]]
		+	[[Category: Bebrone, C.]]
		+	[[Category: Delbruck, H.]]
		+	[[Category: Hoffmann, K M.V.]]
		+	[[Category: Beta lactamase fold]]
		+	[[Category: Beta lactam]]
		+	[[Category: Hydrolase]]

OCA at 08:11, 29 February 2012

2012-02-29T08:11:59Z

←Older revision		Revision as of 08:11, 29 February 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3tsg is ON HOLD	+	The entry 3tsg is ON HOLD until Paper Publication

	Authors: Delbruck, H., Hoffmann, K.M.V., Bebrone, C.		Authors: Delbruck, H., Hoffmann, K.M.V., Bebrone, C.

	Description: Crystal structure of GES-14		Description: Crystal structure of GES-14

OCA: Protected "3tsg" [edit=sysop:move=sysop]

2011-09-21T05:33:56Z

Protected "3tsg" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:33, 21 September 2011

OCA: New page: '''Unreleased structure''' The entry 3tsg is ON HOLD Authors: Delbruck, H., Hoffmann, K.M.V., Bebrone, C. Description: Crystal structure of GES-14

2011-09-21T05:33:55Z

New page: '''Unreleased structure''' The entry 3tsg is ON HOLD Authors: Delbruck, H., Hoffmann, K.M.V., Bebrone, C. Description: Crystal structure of GES-14

New page

'''Unreleased structure'''

The entry 3tsg is ON HOLD

Authors: Delbruck, H., Hoffmann, K.M.V., Bebrone, C.

Description: Crystal structure of GES-14