3u7g - Revision history

OCA at 06:01, 13 July 2022

2022-07-13T06:01:11Z

←Older revision		Revision as of 06:01, 13 July 2022
Line 1:		Line 1:

	==Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)==		==Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)==
-	<StructureSection load='3u7g' size='340' side='right' caption='[[3u7g]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='3u7g' size='340' side='right'caption='[[3u7g]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3u7g]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7G OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3U7G FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3u7g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U7G FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yj5\|1yj5]], [[3u7e\|3u7e]], [[3u7f\|3u7f]], [[3u7h\|3u7h]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1yj5\|1yj5]], [[3u7e\|3u7e]], [[3u7f\|3u7f]], [[3u7h\|3u7h]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Pnkp ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Pnkp ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3u7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7g OCA], [~~http~~://pdbe.org/3u7g PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3u7g RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3u7g PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3u7g ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7g OCA], [https://pdbe.org/3u7g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u7g RCSB], [https://www.ebi.ac.uk/pdbsum/3u7g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u7g ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/PNKP_MOUSE PNKP_MOUSE]] Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone.	+	[[https://www.uniprot.org/uniprot/PNKP_MOUSE PNKP_MOUSE]] Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Lk3 transgenic mice]]		[[Category: Lk3 transgenic mice]]
	[[Category: Bernstein, N]]		[[Category: Bernstein, N]]

OCA at 08:03, 4 August 2016

2016-08-04T08:03:49Z

←Older revision		Revision as of 08:03, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)==		==Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)==
	<StructureSection load='3u7g' size='340' side='right' caption='[[3u7g]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3u7g' size='340' side='right' caption='[[3u7g]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3u7g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U7G FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3u7g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U7G FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yj5\|1yj5]], [[3u7e\|3u7e]], [[3u7f\|3u7f]], [[3u7h\|3u7h]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yj5\|1yj5]], [[3u7e\|3u7e]], [[3u7f\|3u7f]], [[3u7h\|3u7h]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Pnkp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 ~~Mus musculus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Pnkp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u7g RCSB], [http://www.ebi.ac.uk/pdbsum/3u7g PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7g OCA], [http://pdbe.org/3u7g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3u7g RCSB], [http://www.ebi.ac.uk/pdbsum/3u7g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3u7g ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3u7g" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mus musculus~~]]	+	[[Category: Lk3 transgenic mice]]
	[[Category: Bernstein, N]]		[[Category: Bernstein, N]]
	[[Category: Coquelle, N]]		[[Category: Coquelle, N]]

OCA at 07:22, 24 December 2014

2014-12-24T07:22:47Z

←Older revision		Revision as of 07:22, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3u7g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U7G FirstGlance]. <br>		<table><tr><td colspan='2'>[[3u7g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U7G FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yj5\|1yj5]], [[3u7e\|3u7e]], [[3u7f\|3u7f]], [[3u7h\|3u7h]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yj5\|1yj5]], [[3u7e\|3u7e]], [[3u7f\|3u7f]], [[3u7h\|3u7h]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Pnkp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Pnkp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u7g RCSB], [http://www.ebi.ac.uk/pdbsum/3u7g PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u7g RCSB], [http://www.ebi.ac.uk/pdbsum/3u7g PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PNKP_MOUSE PNKP_MOUSE]] Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Bernstein, N.]]	+	[[Category: Bernstein, N]]
-	[[Category: Coquelle, N.]]	+	[[Category: Coquelle, N]]
-	[[Category: Glover, J N.M.]]	+	[[Category: Glover, J N.M]]
-	[[Category: Green, R.]]	+	[[Category: Green, R]]
-	[[Category: Havali, Z.]]	+	[[Category: Havali, Z]]
	[[Category: Dna repair]]		[[Category: Dna repair]]
	[[Category: Had family]]		[[Category: Had family]]

OCA at 09:15, 11 June 2014

2014-06-11T09:15:09Z

←Older revision		Revision as of 09:15, 11 June 2014
Line 1:		Line 1:
-	[[~~Image:~~3u7g.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)==
		+	<StructureSection load='3u7g' size='340' side='right' caption='[[3u7g]], [[Resolution\|resolution]] 2.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3u7g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U7G FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yj5\|1yj5]], [[3u7e\|3u7e]], [[3u7f\|3u7f]], [[3u7h\|3u7h]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Pnkp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u7g RCSB], [http://www.ebi.ac.uk/pdbsum/3u7g PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Polynucleotide kinase/phosphatase (PNKP) is a critical mammalian DNA repair enzyme that generates 5'-phosphate and 3'-hydroxyl groups at damaged DNA termini that are required for subsequent processing by DNA ligases and polymerases. The PNKP phosphatase domain recognizes 3'-phosphate termini within DNA nicks, gaps, or at double- or single-strand breaks. Here we present a mechanistic rationale for the recognition of damaged DNA termini by the PNKP phosphatase domain. The crystal structures of PNKP bound to single-stranded DNA substrates reveals a narrow active site cleft that accommodates a single-stranded substrate in a sequence-independent manner. Biochemical studies suggest that the terminal base pairs of double-stranded substrates near the 3'-phosphate are destabilized by PNKP to allow substrate access to the active site. A positively charged surface distinct from the active site specifically facilitates interactions with double-stranded substrates, providing a complex DNA binding surface that enables the recognition of diverse substrates.

-	~~{{STRUCTURE_3u7g\| PDB=3u7g \| SCENE= }}~~	+	Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.,Coquelle N, Havali-Shahriari Z, Bernstein N, Green R, Glover JN Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21022-7. Epub 2011 Dec 14. PMID:22171004<ref>PMID:22171004</ref>

-	~~===Crystal structure~~ of ~~mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22171004}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3u7g]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Mus_musculus Mus musculus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3U7G OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022171004<~~/~~ref~~><~~ref group="xtra">PMID:015749016</ref><references group="xtra"~~/>	+
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Bernstein, N.]]		[[Category: Bernstein, N.]]

OCA at 05:11, 29 August 2012

2012-08-29T05:11:45Z

←Older revision		Revision as of 05:11, 29 August 2012
Line 1:		Line 1:
-	[[Image:3u7g.~~jpg~~\|left\|200px]]	+	[[Image:3u7g.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_3u7g\| PDB=3u7g \| SCENE= }}		{{STRUCTURE_3u7g\| PDB=3u7g \| SCENE= }}

	===Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)===		===Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)===

-		+	{{ABSTRACT_PUBMED_22171004}}
-	~~<!--~~	+
-	~~The line below this paragraph,~~ {{~~ABSTRACT_PUBMED_15749016}}, adds the Publication Abstract to the page~~	+
-	~~(as it appears on PubMed at http://www.pubmed.gov), where 15749016 is the PubMed ID number.~~	+
-	~~-->~~	+
-	~~{{ABSTRACT_PUBMED_15749016~~}}	+

	==About this Structure==		==About this Structure==
Line 22:		Line 11:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:015749016</ref><references group="xtra"/>	+	<ref group="xtra">PMID:022171004</ref><ref group="xtra">PMID:015749016</ref><references group="xtra"/>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Bernstein, N.]]		[[Category: Bernstein, N.]]

OCA at 11:52, 14 December 2011

2011-12-14T11:52:03Z

←Older revision		Revision as of 11:52, 14 December 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3u7g.jpg\|left\|200px]]

-	The ~~entry 3u7g~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3u7g", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3u7g\| PDB=3u7g \| SCENE= }}

-	~~Authors: Coquelle, N., Havali, Z., Bernstein, N., Green, R., Glover, J.N.M.~~	+	===Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)===

-	~~Description: Crystal structure of mPNKP catalytic fragment (D170A) bound to single~~-~~stranded DNA~~ (~~TCCTAp~~)	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_15749016}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 15749016 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_15749016}}
		+
		+	==About this Structure==
		+	[[3u7g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7G OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:015749016</ref><references group="xtra"/>
		+	[[Category: Mus musculus]]
		+	[[Category: Bernstein, N.]]
		+	[[Category: Coquelle, N.]]
		+	[[Category: Glover, J N.M.]]
		+	[[Category: Green, R.]]
		+	[[Category: Havali, Z.]]
		+	[[Category: Dna repair]]
		+	[[Category: Had family]]
		+	[[Category: Hydrolase]]
		+	[[Category: Phosphatase]]
		+	[[Category: Pnkp]]
		+	[[Category: Protein-dna complex]]
		+	[[Category: Transferase-dna complex]]

OCA at 05:50, 30 November 2011

2011-11-30T05:50:06Z

←Older revision		Revision as of 05:50, 30 November 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3u7g is ON HOLD until ~~sometime in the future~~	+	The entry 3u7g is ON HOLD until Paper Publication

	Authors: Coquelle, N., Havali, Z., Bernstein, N., Green, R., Glover, J.N.M.		Authors: Coquelle, N., Havali, Z., Bernstein, N., Green, R., Glover, J.N.M.

	Description: Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)		Description: Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)

OCA at 11:14, 9 November 2011

2011-11-09T11:14:43Z

←Older revision		Revision as of 11:14, 9 November 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3u7g is ON HOLD	+	The entry 3u7g is ON HOLD until sometime in the future

	Authors: Coquelle, N., Havali, Z., Bernstein, N., Green, R., Glover, J.N.M.		Authors: Coquelle, N., Havali, Z., Bernstein, N., Green, R., Glover, J.N.M.

	Description: Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)		Description: Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)

OCA: Protected "3u7g" [edit=sysop:move=sysop]

2011-10-30T08:53:52Z

Protected "3u7g" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:53, 30 October 2011

OCA: New page: '''Unreleased structure''' The entry 3u7g is ON HOLD Authors: Coquelle, N., Havali, Z., Bernstein, N., Green, R., Glover, J.N.M. Description: Crystal structure of mPNKP catalytic fragm...

2011-10-30T08:53:52Z

New page: '''Unreleased structure''' The entry 3u7g is ON HOLD Authors: Coquelle, N., Havali, Z., Bernstein, N., Green, R., Glover, J.N.M. Description: Crystal structure of mPNKP catalytic fragm...

New page

'''Unreleased structure'''

The entry 3u7g is ON HOLD

Authors: Coquelle, N., Havali, Z., Bernstein, N., Green, R., Glover, J.N.M.

Description: Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)