3vas - Revision history

OCA at 14:22, 14 March 2024

2024-03-14T14:22:25Z

←Older revision		Revision as of 14:22, 14 March 2024
Line 3:		Line 3:
	<StructureSection load='3vas' size='340' side='right'caption='[[3vas]], [[Resolution\|resolution]] 2.26Å' scene=''>		<StructureSection load='3vas' size='340' side='right'caption='[[3vas]], [[Resolution\|resolution]] 2.26Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vas]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Blood_fluke Blood fluke~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VAS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vas]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VAS FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>~~, ~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.26Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[3uq6\|3uq6]], [[3uq9\|3uq9]], [[3vaq\|3vaq]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>Smp_008360 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~6183 Blood fluke])</td~~><~~/tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vas OCA], [https://pdbe.org/3vas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vas RCSB], [https://www.ebi.ac.uk/pdbsum/3vas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vas ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vas OCA], [https://pdbe.org/3vas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vas RCSB], [https://www.ebi.ac.uk/pdbsum/3vas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vas ProSAT]</span></td></tr>
	</table>		</table>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	In adult schistosomes, the enzyme adenosine kinase (AK) is responsible for the incorporation of some adenosine analogues, such as 2-fluoroadenosine and tubercidin, into the nucleotide pool, but not others. In the present study, the structures of four complexes of Schistosoma mansoni AK bound to adenosine and adenosine analogues are reported which shed light on this observation. Two differences in the adenosine-binding site in comparison with the human counterpart (I38Q and T36A) are responsible for their differential specificities towards adenosine analogues, in which the Schistosoma enzyme does not tolerate bulky substituents at the N7 base position. This aids in explaining experimental data which were reported in the literature more than two decades ago. Furthermore, there appears to be considerable plasticity within the substrate-binding sites that affects the side-chain conformation of Ile38 and causes a previously unobserved flexibility within the loop comprising residues 286-299. These results reveal that the latter can be sterically occluded in the absence of ATP. Overall, these results contribute to the body of knowledge concerning the enzymes of the purine salvage pathway in this important human parasite.
-
-	Adenosine kinase from Schistosoma mansoni: structural basis for the differential incorporation of nucleoside analogues.,Romanello L, Bachega JF, Cassago A, Brandao-Neto J, Demarco R, Garratt RC, Pereira HD Acta Crystallogr D Biol Crystallogr. 2013 Jan;69(Pt 1):126-36. doi:, 10.1107/S0907444912044800. Epub 2012 Dec 20. PMID:23275171<ref>PMID:23275171</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3vas" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Adenosine kinase]]
-	[[Category: Blood fluke]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bachega~~, F R~~]]	+	[[Category: Schistosoma mansoni]]
-	[[Category: Brandao-neto, J]]	+	[[Category: Bachega FR]]
-	[[Category: DeMarco, R]]	+	[[Category: Brandao-neto J]]
-	[[Category: Garatt~~, R C~~]]	+	[[Category: DeMarco R]]
-	[[Category: Pereira~~, H M~~]]	+	[[Category: Garatt RC]]
-	[[Category: Romanello, L]]	+	[[Category: Pereira HM]]
-	~~[[Category: Enzyme]]~~	+	[[Category: Romanello L]]
-	~~[[Category: Ribokinase]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 18:35, 27 July 2022

2022-07-27T18:35:44Z

←Older revision		Revision as of 18:35, 27 July 2022
Line 1:		Line 1:

	==Adenosine kinase from Schistosoma mansoni in complex with adenosine in occluded loop conformation==		==Adenosine kinase from Schistosoma mansoni in complex with adenosine in occluded loop conformation==
-	<StructureSection load='3vas' size='340' side='right' caption='[[3vas]], [[Resolution\|resolution]] 2.26Å' scene=''>	+	<StructureSection load='3vas' size='340' side='right'caption='[[3vas]], [[Resolution\|resolution]] 2.26Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vas]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Blood_fluke Blood fluke]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VAS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3VAS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vas]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Blood_fluke Blood fluke]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VAS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3uq6\|3uq6]], [[3uq9\|3uq9]], [[3vaq\|3vaq]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3uq6\|3uq6]], [[3uq9\|3uq9]], [[3vaq\|3vaq]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Smp_008360 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6183 Blood fluke])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Smp_008360 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6183 Blood fluke])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3vas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vas OCA], [~~http~~://pdbe.org/3vas PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3vas RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3vas PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3vas ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vas OCA], [https://pdbe.org/3vas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vas RCSB], [https://www.ebi.ac.uk/pdbsum/3vas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vas ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 25:
	[[Category: Adenosine kinase]]		[[Category: Adenosine kinase]]
	[[Category: Blood fluke]]		[[Category: Blood fluke]]
		+	[[Category: Large Structures]]
	[[Category: Bachega, F R]]		[[Category: Bachega, F R]]
	[[Category: Brandao-neto, J]]		[[Category: Brandao-neto, J]]

OCA at 09:12, 11 August 2016

2016-08-11T09:12:32Z

←Older revision		Revision as of 09:12, 11 August 2016
Line 1:		Line 1:
		+
	==Adenosine kinase from Schistosoma mansoni in complex with adenosine in occluded loop conformation==		==Adenosine kinase from Schistosoma mansoni in complex with adenosine in occluded loop conformation==
	<StructureSection load='3vas' size='340' side='right' caption='[[3vas]], [[Resolution\|resolution]] 2.26Å' scene=''>		<StructureSection load='3vas' size='340' side='right' caption='[[3vas]], [[Resolution\|resolution]] 2.26Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vas]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Schistosoma_mansoni Schistosoma mansoni~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VAS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VAS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vas]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Blood_fluke Blood fluke]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VAS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VAS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3uq6\|3uq6]], [[3uq9\|3uq9]], [[3vaq\|3vaq]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3uq6\|3uq6]], [[3uq9\|3uq9]], [[3vaq\|3vaq]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Smp_008360 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6183 ~~Schistosoma mansoni~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Smp_008360 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6183 Blood fluke])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vas OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vas RCSB], [http://www.ebi.ac.uk/pdbsum/3vas PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vas OCA], [http://pdbe.org/3vas PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3vas RCSB], [http://www.ebi.ac.uk/pdbsum/3vas PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3vas ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3vas" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
Line 22:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Adenosine kinase]]		[[Category: Adenosine kinase]]
-	[[Category: ~~Schistosoma mansoni~~]]	+	[[Category: Blood fluke]]
	[[Category: Bachega, F R]]		[[Category: Bachega, F R]]
	[[Category: Brandao-neto, J]]		[[Category: Brandao-neto, J]]

OCA at 09:27, 4 January 2015

2015-01-04T09:27:51Z

←Older revision		Revision as of 09:27, 4 January 2015
Line 1:		Line 1:
-	[[~~Image:~~3vas.~~png~~\|~~left~~\|~~200px~~]]	+	==Adenosine kinase from Schistosoma mansoni in complex with adenosine in occluded loop conformation==
		+	<StructureSection load='3vas' size='340' side='right' caption='[[3vas]], [[Resolution\|resolution]] 2.26Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3vas]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VAS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VAS FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3uq6\|3uq6]], [[3uq9\|3uq9]], [[3vaq\|3vaq]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Smp_008360 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6183 Schistosoma mansoni])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vas OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vas RCSB], [http://www.ebi.ac.uk/pdbsum/3vas PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In adult schistosomes, the enzyme adenosine kinase (AK) is responsible for the incorporation of some adenosine analogues, such as 2-fluoroadenosine and tubercidin, into the nucleotide pool, but not others. In the present study, the structures of four complexes of Schistosoma mansoni AK bound to adenosine and adenosine analogues are reported which shed light on this observation. Two differences in the adenosine-binding site in comparison with the human counterpart (I38Q and T36A) are responsible for their differential specificities towards adenosine analogues, in which the Schistosoma enzyme does not tolerate bulky substituents at the N7 base position. This aids in explaining experimental data which were reported in the literature more than two decades ago. Furthermore, there appears to be considerable plasticity within the substrate-binding sites that affects the side-chain conformation of Ile38 and causes a previously unobserved flexibility within the loop comprising residues 286-299. These results reveal that the latter can be sterically occluded in the absence of ATP. Overall, these results contribute to the body of knowledge concerning the enzymes of the purine salvage pathway in this important human parasite.

-	~~{{STRUCTURE_3vas\| PDB=3vas \| SCENE= }}~~	+	Adenosine kinase from Schistosoma mansoni: structural basis for the differential incorporation of nucleoside analogues.,Romanello L, Bachega JF, Cassago A, Brandao-Neto J, Demarco R, Garratt RC, Pereira HD Acta Crystallogr D Biol Crystallogr. 2013 Jan;69(Pt 1):126-36. doi:, 10.1107/S0907444912044800. Epub 2012 Dec 20. PMID:23275171<ref>PMID:23275171</ref>

-	~~===Adenosine kinase from Schistosoma mansoni in complex with adenosine in occluded loop conformation===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_23275171}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[3vas]] is a 2 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VAS OCA].~~	+	</StructureSection>
	[[Category: Adenosine kinase]]		[[Category: Adenosine kinase]]
	[[Category: Schistosoma mansoni]]		[[Category: Schistosoma mansoni]]
-	[[Category: Bachega, F R.]]	+	[[Category: Bachega, F R]]
-	[[Category: Brandao-neto, J.]]	+	[[Category: Brandao-neto, J]]
-	[[Category: DeMarco, R.]]	+	[[Category: DeMarco, R]]
-	[[Category: Garatt, R C.]]	+	[[Category: Garatt, R C]]
-	[[Category: Pereira, H M.]]	+	[[Category: Pereira, H M]]
-	[[Category: Romanello, L.]]	+	[[Category: Romanello, L]]
	[[Category: Enzyme]]		[[Category: Enzyme]]
	[[Category: Ribokinase]]		[[Category: Ribokinase]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 08:53, 16 January 2013

2013-01-16T08:53:49Z

←Older revision		Revision as of 08:53, 16 January 2013
Line 5:		Line 5:
	===Adenosine kinase from Schistosoma mansoni in complex with adenosine in occluded loop conformation===		===Adenosine kinase from Schistosoma mansoni in complex with adenosine in occluded loop conformation===

		+	{{ABSTRACT_PUBMED_23275171}}

	==About this Structure==		==About this Structure==

OCA at 07:55, 2 January 2013

2013-01-02T07:55:53Z

←Older revision		Revision as of 07:55, 2 January 2013
Line 1:		Line 1:
-	[[Image:3vas.~~jpg~~\|left\|200px]]	+	[[Image:3vas.png\|left\|200px]]

	{{STRUCTURE_3vas\| PDB=3vas \| SCENE= }}		{{STRUCTURE_3vas\| PDB=3vas \| SCENE= }}

OCA at 06:52, 14 November 2012

2012-11-14T06:52:45Z

←Older revision		Revision as of 06:52, 14 November 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3vas.jpg\|left\|200px]]

-	~~The entry~~ 3vas ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_3vas\| PDB=3vas \| SCENE= }}

-	~~Authors: Romanello, L., Bachega, F.R., Garatt, R.C., DeMarco, R., Brandao-neto, J., Pereira, H.M.~~	+	===Adenosine kinase from Schistosoma mansoni in complex with adenosine in occluded loop conformation===

-	~~Description~~: Adenosine kinase ~~from~~ Schistosoma mansoni ~~in complex with adenosine in occluded loop conformation~~	+
		+	==About this Structure==
		+	[[3vas]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VAS OCA].
		+	[[Category: Adenosine kinase]]
		+	[[Category: Schistosoma mansoni]]
		+	[[Category: Bachega, F R.]]
		+	[[Category: Brandao-neto, J.]]
		+	[[Category: DeMarco, R.]]
		+	[[Category: Garatt, R C.]]
		+	[[Category: Pereira, H M.]]
		+	[[Category: Romanello, L.]]
		+	[[Category: Enzyme]]
		+	[[Category: Ribokinase]]
		+	[[Category: Transferase]]

OCA at 06:03, 25 January 2012

2012-01-25T06:03:21Z

←Older revision		Revision as of 06:03, 25 January 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3vas is ON HOLD	+	The entry 3vas is ON HOLD until Paper Publication

	Authors: Romanello, L., Bachega, F.R., Garatt, R.C., DeMarco, R., Brandao-neto, J., Pereira, H.M.		Authors: Romanello, L., Bachega, F.R., Garatt, R.C., DeMarco, R., Brandao-neto, J., Pereira, H.M.

	Description: Adenosine kinase from Schistosoma mansoni in complex with adenosine in occluded loop conformation		Description: Adenosine kinase from Schistosoma mansoni in complex with adenosine in occluded loop conformation

OCA at 10:19, 18 January 2012

2012-01-18T10:19:08Z

←Older revision		Revision as of 10:19, 18 January 2012
Line 3:		Line 3:
	The entry 3vas is ON HOLD		The entry 3vas is ON HOLD

-	Authors: Romanello, L., Bachega, F.R., Garatt,R.C., DeMarco,R., Brandao-neto, J., Pereira,H.M.	+	Authors: Romanello, L., Bachega, F.R., Garatt, R.C., DeMarco, R., Brandao-neto, J., Pereira, H.M.

	Description: Adenosine kinase from Schistosoma mansoni in complex with adenosine in occluded loop conformation		Description: Adenosine kinase from Schistosoma mansoni in complex with adenosine in occluded loop conformation

OCA: Protected "3vas" [edit=sysop:move=sysop]

2012-01-04T05:48:35Z

Protected "3vas" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:48, 4 January 2012