3vmq - Revision history

OCA at 12:27, 8 November 2023

2023-11-08T12:27:36Z

←Older revision		Revision as of 12:27, 8 November 2023
Line 3:		Line 3:
	<StructureSection load='3vmq' size='340' side='right'caption='[[3vmq]], [[Resolution\|resolution]] 2.52Å' scene=''>		<StructureSection load='3vmq' size='340' side='right'caption='[[3vmq]], [[Resolution\|resolution]] 2.52Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vmq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Staam Staam~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VMQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vmq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VMQ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.518Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>~~[[3vmr\|3vmr]], [[3vms\|3vms]], [[3vmt\|3vmt]]~~<~~/div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">mgt ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 STAAM])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vmq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vmq OCA], [https://pdbe.org/3vmq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vmq RCSB], [https://www.ebi.ac.uk/pdbsum/3vmq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vmq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vmq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vmq OCA], [https://pdbe.org/3vmq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vmq RCSB], [https://www.ebi.ac.uk/pdbsum/3vmq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vmq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/MGT_STAAM MGT_STAAM]] Involved in the biosynthesis of cell wall peptidoglycan. Responsible for the elongation of the glycan strands using lipid-linked disaccharide-pentapeptide as the substrate (By similarity).	+	[https://www.uniprot.org/uniprot/MGT_STAAM MGT_STAAM] Involved in the biosynthesis of cell wall peptidoglycan. Responsible for the elongation of the glycan strands using lipid-linked disaccharide-pentapeptide as the substrate (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 28:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Staam~~]]	+	[[Category: Staphylococcus aureus subsp. aureus Mu50]]
-	[[Category: Cheng~~, T J.R~~]]	+	[[Category: Cheng TJR]]
-	[[Category: Cheng~~, W C~~]]	+	[[Category: Cheng WC]]
-	[[Category: Huang~~, C Y~~]]	+	[[Category: Huang CY]]
-	[[Category: Lin~~, L Y~~]]	+	[[Category: Lin LY]]
-	[[Category: Ma, C]]	+	[[Category: Ma C]]
-	[[Category: Shih~~, H W~~]]	+	[[Category: Shih HW]]
-	[[Category: Tien~~, Y W~~]]	+	[[Category: Tien YW]]
-	[[Category: Wong~~, C H]]~~	+	[[Category: Wong CH]]
-	~~[[Category: Bacterial cell wall synthesis]]~~	+
-	~~[[Category: Glycosyltransferase]]~~	+
-	~~[[Category: Membrane]]~~	+
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Transmembrane~~]]	+

OCA at 18:53, 27 July 2022

2022-07-27T18:53:12Z

←Older revision		Revision as of 18:53, 27 July 2022
Line 1:		Line 1:

	==Crystal structure of Staphylococcus aureus membrane-bound transglycosylase: Apoenzyme==		==Crystal structure of Staphylococcus aureus membrane-bound transglycosylase: Apoenzyme==
-	<StructureSection load='3vmq' size='340' side='right' caption='[[3vmq]], [[Resolution\|resolution]] 2.52Å' scene=''>	+	<StructureSection load='3vmq' size='340' side='right'caption='[[3vmq]], [[Resolution\|resolution]] 2.52Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vmq]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Staam Staam]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3VMQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vmq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staam Staam]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VMQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vmr\|3vmr]], [[3vms\|3vms]], [[3vmt\|3vmt]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3vmr\|3vmr]], [[3vms\|3vms]], [[3vmt\|3vmt]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mgt ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 STAAM])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mgt ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 STAAM])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3vmq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vmq OCA], [~~http~~://pdbe.org/3vmq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3vmq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3vmq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3vmq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vmq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vmq OCA], [https://pdbe.org/3vmq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vmq RCSB], [https://www.ebi.ac.uk/pdbsum/3vmq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vmq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/MGT_STAAM MGT_STAAM]] Involved in the biosynthesis of cell wall peptidoglycan. Responsible for the elongation of the glycan strands using lipid-linked disaccharide-pentapeptide as the substrate (By similarity).	+	[[https://www.uniprot.org/uniprot/MGT_STAAM MGT_STAAM]] Involved in the biosynthesis of cell wall peptidoglycan. Responsible for the elongation of the glycan strands using lipid-linked disaccharide-pentapeptide as the substrate (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:

	==See Also==		==See Also==
-	*[[Glycosyltransferase\|Glycosyltransferase]]	+	*[[Glycosyltransferase 3D structures\|Glycosyltransferase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Staam]]		[[Category: Staam]]
	[[Category: Cheng, T J.R]]		[[Category: Cheng, T J.R]]

OCA at 11:01, 5 August 2016

2016-08-05T11:01:41Z

←Older revision		Revision as of 11:01, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of Staphylococcus aureus membrane-bound transglycosylase: Apoenzyme==		==Crystal structure of Staphylococcus aureus membrane-bound transglycosylase: Apoenzyme==
	<StructureSection load='3vmq' size='340' side='right' caption='[[3vmq]], [[Resolution\|resolution]] 2.52Å' scene=''>		<StructureSection load='3vmq' size='340' side='right' caption='[[3vmq]], [[Resolution\|resolution]] 2.52Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vmq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Staphylococcus_aureus_subsp._aureus_mu50 Staphylococcus aureus subsp. aureus mu50~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VMQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vmq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staam Staam]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VMQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vmr\|3vmr]], [[3vms\|3vms]], [[3vmt\|3vmt]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vmr\|3vmr]], [[3vms\|3vms]], [[3vmt\|3vmt]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mgt ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 ~~Staphylococcus aureus subsp. aureus Mu50~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mgt ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 STAAM])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vmq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vmq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vmq RCSB], [http://www.ebi.ac.uk/pdbsum/3vmq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vmq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vmq OCA], [http://pdbe.org/3vmq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3vmq RCSB], [http://www.ebi.ac.uk/pdbsum/3vmq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3vmq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3vmq" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 25:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Staphylococcus aureus subsp. aureus mu50~~]]	+	[[Category: Staam]]
	[[Category: Cheng, T J.R]]		[[Category: Cheng, T J.R]]
	[[Category: Cheng, W C]]		[[Category: Cheng, W C]]

OCA at 18:15, 25 December 2014

2014-12-25T18:15:25Z

←Older revision		Revision as of 18:15, 25 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3vmq\| PDB=3vmq \| SCENE= }}~~	+	==Crystal structure of Staphylococcus aureus membrane-bound transglycosylase: Apoenzyme==
-	===Crystal structure of Staphylococcus aureus membrane-bound transglycosylase: Apoenzyme===	+	<StructureSection load='3vmq' size='340' side='right' caption='[[3vmq]], [[Resolution\|resolution]] 2.52Å' scene=''>
-	~~{{ABSTRACT_PUBMED_22493270}}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[3vmq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mu50 Staphylococcus aureus subsp. aureus mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VMQ FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vmr\|3vmr]], [[3vms\|3vms]], [[3vmt\|3vmt]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mgt ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 Staphylococcus aureus subsp. aureus Mu50])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vmq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vmq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vmq RCSB], [http://www.ebi.ac.uk/pdbsum/3vmq PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/MGT_STAAM MGT_STAAM]] Involved in the biosynthesis of cell wall peptidoglycan. Responsible for the elongation of the glycan strands using lipid-linked disaccharide-pentapeptide as the substrate (By similarity).		[[http://www.uniprot.org/uniprot/MGT_STAAM MGT_STAAM]] Involved in the biosynthesis of cell wall peptidoglycan. Responsible for the elongation of the glycan strands using lipid-linked disaccharide-pentapeptide as the substrate (By similarity).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bacterial transpeptidase and transglycosylase on the surface are essential for cell wall synthesis, and many antibiotics have been developed to target the transpeptidase; however, the problem of antibiotic resistance has arisen and caused a major threat in bacterial infection. The transglycosylase has been considered to be another excellent target, but no antibiotics have been developed to target this enzyme. Here, we determined the crystal structure of the Staphylococcus aureus membrane-bound transglycosylase, monofunctional glycosyltransferase, in complex with a lipid II analog to 2.3 A resolution. Our results showed that the lipid II-contacting residues are not only conserved in WT and drug-resistant bacteria but also significant in enzymatic activity. Mechanistically, we proposed that K140 and R148 in the donor site, instead of the previously proposed E156, are used to stabilize the pyrophosphate-leaving group of lipid II, and E100 in the acceptor site acts as general base for the 4-OH of GlcNAc to facilitate the transglycosylation reaction. This mechanism, further supported by mutagenesis study and the structure of monofunctional glycosyltransferase in complex with moenomycin in the donor site, provides a direction for antibacterial drugs design.

-	~~==About this Structure==~~	+	Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism.,Huang CY, Shih HW, Lin LY, Tien YW, Cheng TJ, Cheng WC, Wong CH, Ma C Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6496-501. Epub 2012 Apr 9. PMID:22493270<ref>PMID:22493270</ref>
-	~~[[3vmq]] is a 2 chain~~ structure with ~~sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Staphylococcus_aureus_subsp~~.~~_aureus_mu50 Staphylococcus aureus subsp. aureus mu50]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3VMQ OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Glycosyltransferase\|Glycosyltransferase]]		*[[Glycosyltransferase\|Glycosyltransferase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:022493270</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Staphylococcus aureus subsp. aureus mu50]]		[[Category: Staphylococcus aureus subsp. aureus mu50]]
-	[[Category: Cheng, T J.R.]]	+	[[Category: Cheng, T J.R]]
-	[[Category: Cheng, W C.]]	+	[[Category: Cheng, W C]]
-	[[Category: Huang, C Y.]]	+	[[Category: Huang, C Y]]
-	[[Category: Lin, L Y.]]	+	[[Category: Lin, L Y]]
-	[[Category: Ma, C.]]	+	[[Category: Ma, C]]
-	[[Category: Shih, H W.]]	+	[[Category: Shih, H W]]
-	[[Category: Tien, Y W.]]	+	[[Category: Tien, Y W]]
-	[[Category: Wong, C H.]]	+	[[Category: Wong, C H]]
	[[Category: Bacterial cell wall synthesis]]		[[Category: Bacterial cell wall synthesis]]
	[[Category: Glycosyltransferase]]		[[Category: Glycosyltransferase]]

OCA at 04:35, 18 July 2013

2013-07-18T04:35:06Z

←Older revision		Revision as of 04:35, 18 July 2013
Line 1:		Line 1:
-	[[Image:3vmq.png\|left\|200px]]
-
	{{STRUCTURE_3vmq\| PDB=3vmq \| SCENE= }}		{{STRUCTURE_3vmq\| PDB=3vmq \| SCENE= }}
-
	===Crystal structure of Staphylococcus aureus membrane-bound transglycosylase: Apoenzyme===		===Crystal structure of Staphylococcus aureus membrane-bound transglycosylase: Apoenzyme===
		+	{{ABSTRACT_PUBMED_22493270}}

		+	==Function==
		+	[[http://www.uniprot.org/uniprot/MGT_STAAM MGT_STAAM]] Involved in the biosynthesis of cell wall peptidoglycan. Responsible for the elongation of the glycan strands using lipid-linked disaccharide-pentapeptide as the substrate (By similarity).

	==About this Structure==		==About this Structure==
-	[[3vmq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Staphylococcus_aureus~~ Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMQ OCA].	+	[[3vmq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mu50 Staphylococcus aureus subsp. aureus mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMQ OCA].

	==See Also==		==See Also==
	*[[Glycosyltransferase\|Glycosyltransferase]]		*[[Glycosyltransferase\|Glycosyltransferase]]
-	[[Category: Staphylococcus aureus]]	+
		+	==Reference==
		+	<ref group="xtra">PMID:022493270</ref><references group="xtra"/><references/>
		+	[[Category: Staphylococcus aureus subsp. aureus mu50]]
	[[Category: Cheng, T J.R.]]		[[Category: Cheng, T J.R.]]
	[[Category: Cheng, W C.]]		[[Category: Cheng, W C.]]

OCA at 19:52, 20 October 2012

2012-10-20T19:52:02Z

←Older revision		Revision as of 19:52, 20 October 2012
Line 7:		Line 7:

	==About this Structure==		==About this Structure==
-	[[3vmq]] is a 2 chain structure ~~of [[Glycosyltransferase]]~~ with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMQ OCA].	+	[[3vmq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMQ OCA].

	==See Also==		==See Also==

OCA at 08:43, 27 July 2012

2012-07-27T08:43:42Z

←Older revision		Revision as of 08:43, 27 July 2012
Line 1:		Line 1:
-	[[Image:3vmq.~~jpg~~\|left\|200px]]	+	[[Image:3vmq.png\|left\|200px]]

-	<!--
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-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_3vmq\| PDB=3vmq \| SCENE= }}		{{STRUCTURE_3vmq\| PDB=3vmq \| SCENE= }}

Line 13:		Line 7:

	==About this Structure==		==About this Structure==
-	[[3vmq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMQ OCA].	+	[[3vmq]] is a 2 chain structure of [[Glycosyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMQ OCA].
		+
		+	==See Also==
		+	*[[Glycosyltransferase\|Glycosyltransferase]]
	[[Category: Staphylococcus aureus]]		[[Category: Staphylococcus aureus]]
	[[Category: Cheng, T J.R.]]		[[Category: Cheng, T J.R.]]

OCA at 07:58, 18 April 2012

2012-04-18T07:58:29Z

←Older revision		Revision as of 07:58, 18 April 2012
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-	~~'''Unreleased structure'''~~	+	[[Image:3vmq.jpg\|left\|200px]]

-	The ~~entry 3vmq~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3vmq", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3vmq\| PDB=3vmq \| SCENE= }}

-	~~Authors~~: ~~Huang, C.Y., Shih, H.W., Lin, L.Y., Tien, Y.W., Cheng, T.J., Cheng, W.C., Wong, C.H., Ma, C.~~	+	===Crystal structure of Staphylococcus aureus membrane-bound transglycosylase: Apoenzyme===

-	~~Description: Crystal~~ structure of Staphylococcus aureus ~~membrane~~-~~bound transglycosylase~~: ~~Apoenzyme~~	+
		+	==About this Structure==
		+	[[3vmq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMQ OCA].
		+	[[Category: Staphylococcus aureus]]
		+	[[Category: Cheng, T J.R.]]
		+	[[Category: Cheng, W C.]]
		+	[[Category: Huang, C Y.]]
		+	[[Category: Lin, L Y.]]
		+	[[Category: Ma, C.]]
		+	[[Category: Shih, H W.]]
		+	[[Category: Tien, Y W.]]
		+	[[Category: Wong, C H.]]
		+	[[Category: Bacterial cell wall synthesis]]
		+	[[Category: Glycosyltransferase]]
		+	[[Category: Membrane]]
		+	[[Category: Transferase]]
		+	[[Category: Transmembrane]]

OCA at 06:03, 11 January 2012

2012-01-11T06:03:29Z

←Older revision		Revision as of 06:03, 11 January 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3vmq is ON HOLD	+	The entry 3vmq is ON HOLD until Paper Publication

	Authors: Huang, C.Y., Shih, H.W., Lin, L.Y., Tien, Y.W., Cheng, T.J., Cheng, W.C., Wong, C.H., Ma, C.		Authors: Huang, C.Y., Shih, H.W., Lin, L.Y., Tien, Y.W., Cheng, T.J., Cheng, W.C., Wong, C.H., Ma, C.

-	Description: Crystal structure of Staphylococcus aureus membrane-bound transglycosylase ~~in complex with a lipid II analog and elucidation of the mechanism of peptidoglycan synthesis~~	+	Description: Crystal structure of Staphylococcus aureus membrane-bound transglycosylase: Apoenzyme

OCA: Protected "3vmq" [edit=sysop:move=sysop]

2011-12-28T06:57:28Z

Protected "3vmq" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:57, 28 December 2011