3vor - Revision history

OCA at 18:56, 27 July 2022

2022-07-27T18:56:08Z

←Older revision		Revision as of 18:56, 27 July 2022
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	==Crystal Structure Analysis of the CofA==		==Crystal Structure Analysis of the CofA==
-	<StructureSection load='3vor' size='340' side='right' caption='[[3vor]], [[Resolution\|resolution]] 0.90Å' scene=''>	+	<StructureSection load='3vor' size='340' side='right'caption='[[3vor]], [[Resolution\|resolution]] 0.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vor]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VOR OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3VOR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vor]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VOR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VOR FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cofA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cofA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3vor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vor OCA], [~~http~~://pdbe.org/3vor PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3vor RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3vor PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3vor ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vor OCA], [https://pdbe.org/3vor PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vor RCSB], [https://www.ebi.ac.uk/pdbsum/3vor PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vor ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	==See Also==		==See Also==
-	*[[Pilin\|Pilin]]	+	*[[Pilin 3D structures\|Pilin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 24:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Baba, S]]		[[Category: Baba, S]]
	[[Category: Fukakusa, S]]		[[Category: Fukakusa, S]]

OCA at 11:19, 11 August 2016

2016-08-11T11:19:38Z

←Older revision		Revision as of 11:19, 11 August 2016
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		+
	==Crystal Structure Analysis of the CofA==		==Crystal Structure Analysis of the CofA==
	<StructureSection load='3vor' size='340' side='right' caption='[[3vor]], [[Resolution\|resolution]] 0.90Å' scene=''>		<StructureSection load='3vor' size='340' side='right' caption='[[3vor]], [[Resolution\|resolution]] 0.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vor]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VOR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VOR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vor]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VOR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VOR FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cofA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 ~~Escherichia~~ coli])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cofA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vor OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vor RCSB], [http://www.ebi.ac.uk/pdbsum/3vor PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vor OCA], [http://pdbe.org/3vor PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3vor RCSB], [http://www.ebi.ac.uk/pdbsum/3vor PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3vor ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3vor" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 21:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Baba, S]]		[[Category: Baba, S]]
	[[Category: Fukakusa, S]]		[[Category: Fukakusa, S]]

OCA at 06:39, 22 January 2015

2015-01-22T06:39:51Z

←Older revision		Revision as of 06:39, 22 January 2015
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-	~~{{STRUCTURE_3vor\| PDB~~=3vor \| ~~SCENE~~= }}	+	==Crystal Structure Analysis of the CofA==
-	===~~Crystal Structure Analysis of~~ the ~~CofA~~===	+	<StructureSection load='3vor' size='340' side='right' caption='[[3vor]], [[Resolution\|resolution]] 0.90Å' scene=''>
-	~~{{ABSTRACT_PUBMED_22993096}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3vor]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VOR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VOR FirstGlance]. <br>
		+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cofA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vor OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vor RCSB], [http://www.ebi.ac.uk/pdbsum/3vor PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	CofA, a major pilin subunit of colonization factor antigen III (CFA/III), forms pili that mediate small-intestinal colonization by enterotoxigenic Escherichia coli (ETEC). In this study, the crystal structure of an N-terminally truncated version of CofA was determined by single-wavelength anomalous diffraction (SAD) phasing using five sulfurs in the protein. Given the counterbalance between anomalous signal strength and the undesired X-ray absorption of the solvent, diffraction data were collected at 1.5 A resolution using synchrotron radiation. These data were sufficient to elucidate the sulfur substructure at 1.38 A resolution. The low solvent content (29%) of the crystal necessitated that density modification be performed with an additional 0.9 A resolution data set to reduce the phase error caused by the small sulfur anomalous signal. The CofA structure showed the alphabeta-fold typical of type IVb pilins and showed high structural homology to that of TcpA for toxin-coregulated pili of Vibrio cholerae, including spatial distribution of key residues critical for pilin self-assembly. A pilus-filament model of CofA was built by computational docking and molecular-dynamics simulation using the previously reported filament model of TcpA as a structural template. This model revealed that the CofA filament surface was highly negatively charged and that a 23-residue-long loop between the alpha1 and alpha2 helices filled the gap between the pilin subunits. These characteristics could provide a unique binding epitope for the CFA/III pili of ETEC compared with other type IVb pili.

-	~~==About this~~ Structure==	+	Structure of the CFA/III major pilin subunit CofA from human enterotoxigenic Escherichia coli determined at 0.90 A resolution by sulfur-SAD phasing.,Fukakusa S, Kawahara K, Nakamura S, Iwashita T, Baba S, Nishimura M, Kobayashi Y, Honda T, Iida T, Taniguchi T, Ohkubo T Acta Crystallogr D Biol Crystallogr. 2012 Oct;68(Pt 10):1418-29. Epub 2012 Sep, 13. PMID:22993096<ref>PMID:22993096</ref>
-	~~[[3vor]] is a 1 chain structure with sequence~~ from ~~[http://en.wikipedia.org/wiki/Escherichia_coli~~ Escherichia coli]. ~~Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=3VOR OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group~~=~~"xtra">PMID:022993096</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+
		+	==See Also==
		+	*[[Pilin\|Pilin]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Baba, S.]]	+	[[Category: Baba, S]]
-	[[Category: Fukakusa, S.]]	+	[[Category: Fukakusa, S]]
-	[[Category: Honda, T.]]	+	[[Category: Honda, T]]
-	[[Category: Iida, T.]]	+	[[Category: Iida, T]]
-	[[Category: Iwasita, T.]]	+	[[Category: Iwasita, T]]
-	[[Category: Kawahara, K.]]	+	[[Category: Kawahara, K]]
-	[[Category: Kobayashi, Y.]]	+	[[Category: Kobayashi, Y]]
-	[[Category: Nakamura, S.]]	+	[[Category: Nakamura, S]]
-	[[Category: Nishimura, M.]]	+	[[Category: Nishimura, M]]
-	[[Category: Ohkubo, T.]]	+	[[Category: Ohkubo, T]]
-	[[Category: Taniguchi, T.]]	+	[[Category: Taniguchi, T]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]
	[[Category: Colonization]]		[[Category: Colonization]]
	[[Category: Type iv pilin]]		[[Category: Type iv pilin]]

OCA at 03:28, 1 August 2013

2013-08-01T03:28:23Z

←Older revision		Revision as of 03:28, 1 August 2013
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-	[[Image:3vor.jpg\|left\|200px]]
-
	{{STRUCTURE_3vor\| PDB=3vor \| SCENE= }}		{{STRUCTURE_3vor\| PDB=3vor \| SCENE= }}
-
	===Crystal Structure Analysis of the CofA===		===Crystal Structure Analysis of the CofA===
-		+	{{ABSTRACT_PUBMED_22993096}}

	==About this Structure==		==About this Structure==
	[[3vor]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VOR OCA].		[[3vor]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VOR OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022993096</ref><references group="xtra"/><references/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Baba, S.]]		[[Category: Baba, S.]]

OCA at 20:45, 26 September 2012

2012-09-26T20:45:30Z

←Older revision		Revision as of 20:45, 26 September 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3vor.jpg\|left\|200px]]

-	~~The entry~~ 3vor ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_3vor\| PDB=3vor \| SCENE= }}

-	~~Authors: Fukakusa, S., Kawahara, K., Nakamura, S., Iwasita, T., Baba, S., Nishimura, M., Kobayashi, Y., Honda ,T., Iida, T., Taniguchi, T., Ohkubo, T.~~	+	===Crystal Structure Analysis of the CofA===

-	~~Description: Crystal~~ Structure ~~Analysis of the CofA~~	+
		+	==About this Structure==
		+	[[3vor]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VOR OCA].
		+	[[Category: Escherichia coli]]
		+	[[Category: Baba, S.]]
		+	[[Category: Fukakusa, S.]]
		+	[[Category: Honda, T.]]
		+	[[Category: Iida, T.]]
		+	[[Category: Iwasita, T.]]
		+	[[Category: Kawahara, K.]]
		+	[[Category: Kobayashi, Y.]]
		+	[[Category: Nakamura, S.]]
		+	[[Category: Nishimura, M.]]
		+	[[Category: Ohkubo, T.]]
		+	[[Category: Taniguchi, T.]]
		+	[[Category: Cell adhesion]]
		+	[[Category: Colonization]]
		+	[[Category: Type iv pilin]]

OCA at 08:16, 29 February 2012

2012-02-29T08:16:57Z

←Older revision		Revision as of 08:16, 29 February 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3vor is ON HOLD	+	The entry 3vor is ON HOLD until Paper Publication

	Authors: Fukakusa, S., Kawahara, K., Nakamura, S., Iwasita, T., Baba, S., Nishimura, M., Kobayashi, Y., Honda ,T., Iida, T., Taniguchi, T., Ohkubo, T.		Authors: Fukakusa, S., Kawahara, K., Nakamura, S., Iwasita, T., Baba, S., Nishimura, M., Kobayashi, Y., Honda ,T., Iida, T., Taniguchi, T., Ohkubo, T.

	Description: Crystal Structure Analysis of the CofA		Description: Crystal Structure Analysis of the CofA

OCA at 07:23, 22 February 2012

2012-02-22T07:23:42Z

←Older revision		Revision as of 07:23, 22 February 2012
Line 3:		Line 3:
	The entry 3vor is ON HOLD		The entry 3vor is ON HOLD

-	Authors: Fukakusa S., Kawahara K., Nakamura S., Iwasita T., Baba S., Nishimura M., Kobayashi Y., Honda T., Iida T., Taniguchi T., Ohkubo T.	+	Authors: Fukakusa, S., Kawahara, K., Nakamura, S., Iwasita, T., Baba, S., Nishimura, M., Kobayashi, Y., Honda ,T., Iida, T., Taniguchi, T., Ohkubo, T.

	Description: Crystal Structure Analysis of the CofA		Description: Crystal Structure Analysis of the CofA

OCA: Protected "3vor" [edit=sysop:move=sysop]

2012-02-15T06:16:06Z

Protected "3vor" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:16, 15 February 2012

OCA: New page: '''Unreleased structure''' The entry 3vor is ON HOLD Authors: Fukakusa S., Kawahara K., Nakamura S., Iwasita T., Baba S., Nishimura M., Kobayashi Y., Honda T., Iida T., Taniguchi T., Oh...

2012-02-15T06:16:05Z

New page: '''Unreleased structure''' The entry 3vor is ON HOLD Authors: Fukakusa S., Kawahara K., Nakamura S., Iwasita T., Baba S., Nishimura M., Kobayashi Y., Honda T., Iida T., Taniguchi T., Oh...

New page

'''Unreleased structure'''

The entry 3vor is ON HOLD

Authors: Fukakusa S., Kawahara K., Nakamura S., Iwasita T., Baba S., Nishimura M., Kobayashi Y., Honda T., Iida T., Taniguchi T., Ohkubo T.

Description: Crystal Structure Analysis of the CofA