3w2y - Revision history

OCA at 12:47, 8 November 2023

2023-11-08T12:47:45Z

←Older revision		Revision as of 12:47, 8 November 2023
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	<StructureSection load='3w2y' size='340' side='right'caption='[[3w2y]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='3w2y' size='340' side='right'caption='[[3w2y]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3w2y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Metth Metth~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W2Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3w2y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._Delta_H Methanothermobacter thermautotrophicus str. Delta H]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W2Y FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>~~, ~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[3w2x\|3w2x]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></~~td><td class="sblockDat"~~>~~MTH212~~, ~~MTH_212 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 METTH])~~<~~/td></tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/Exodeoxyribonuclease_III Exodeoxyribonuclease III], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.11.2 3.1.11.2]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w2y OCA], [https://pdbe.org/3w2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w2y RCSB], [https://www.ebi.ac.uk/pdbsum/3w2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w2y ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w2y OCA], [https://pdbe.org/3w2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w2y RCSB], [https://www.ebi.ac.uk/pdbsum/3w2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w2y ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/UREND_METTH UREND_METTH] Involved in DNA uracil repair (PubMed:17012282, PubMed:19240141, PubMed:20129830). Recognizes DNA uracil residues within double-stranded DNA and initiates DNA-U repair by endonucleotic incision on the 5'-side of the 2'-d-uridine residue, irrespective of the nature of the opposing nucleotide (PubMed:17012282, PubMed:19240141, PubMed:20129830). In addition, acts as an apurinic/apyrimidinic (AP) endonuclease hydrolyzing the DNA phosphodiester backbone immediately at the 5'-side of AP sites, and as a 3'-5' exonuclease (PubMed:15725624, PubMed:17012282). Strongly binds to double-stranded DNA (PubMed:15725624).<ref>PMID:15725624</ref> <ref>PMID:17012282</ref> <ref>PMID:19240141</ref> <ref>PMID:20129830</ref>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Exodeoxyribonuclease III]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Metth~~]]	+	[[Category: Methanothermobacter thermautotrophicus str. Delta H]]
-	[[Category: Arai, R]]	+	[[Category: Arai R]]
-	[[Category: Shida, T]]	+	[[Category: Shida T]]
-	[[Category: Tabata, N]]	+	[[Category: Tabata N]]
-	~~[[Category: Alpha/beta-sandwich]]~~	+
-	~~[[Category: Dna binding]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 05:20, 3 August 2022

2022-08-03T05:20:29Z

←Older revision		Revision as of 05:20, 3 August 2022
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	==Crystal structure of DNA uridine endonuclease Mth212 mutant W205S==		==Crystal structure of DNA uridine endonuclease Mth212 mutant W205S==
-	<StructureSection load='3w2y' size='340' side='right' caption='[[3w2y]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='3w2y' size='340' side='right'caption='[[3w2y]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3w2y]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Metth Metth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W2Y OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3W2Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3w2y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Metth Metth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W2Y FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3w2x\|3w2x]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3w2x\|3w2x]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MTH212, MTH_212 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 METTH])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MTH212, MTH_212 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 METTH])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Exodeoxyribonuclease_III Exodeoxyribonuclease III], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.11.2 3.1.11.2] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Exodeoxyribonuclease_III Exodeoxyribonuclease III], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.11.2 3.1.11.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3w2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w2y OCA], [~~http~~://pdbe.org/3w2y PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3w2y RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3w2y PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3w2y ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w2y OCA], [https://pdbe.org/3w2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w2y RCSB], [https://www.ebi.ac.uk/pdbsum/3w2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w2y ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Exodeoxyribonuclease III]]		[[Category: Exodeoxyribonuclease III]]
		+	[[Category: Large Structures]]
	[[Category: Metth]]		[[Category: Metth]]
	[[Category: Arai, R]]		[[Category: Arai, R]]

OCA at 13:31, 4 August 2016

2016-08-04T13:31:59Z

←Older revision		Revision as of 13:31, 4 August 2016
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		+
	==Crystal structure of DNA uridine endonuclease Mth212 mutant W205S==		==Crystal structure of DNA uridine endonuclease Mth212 mutant W205S==
	<StructureSection load='3w2y' size='340' side='right' caption='[[3w2y]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='3w2y' size='340' side='right' caption='[[3w2y]], [[Resolution\|resolution]] 1.90Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MTH212, MTH_212 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 METTH])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MTH212, MTH_212 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 METTH])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exodeoxyribonuclease_III Exodeoxyribonuclease III], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.11.2 3.1.11.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exodeoxyribonuclease_III Exodeoxyribonuclease III], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.11.2 3.1.11.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w2y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w2y RCSB], [http://www.ebi.ac.uk/pdbsum/3w2y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w2y OCA], [http://pdbe.org/3w2y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3w2y RCSB], [http://www.ebi.ac.uk/pdbsum/3w2y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3w2y ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__

OCA at 17:53, 21 December 2014

2014-12-21T17:53:34Z

←Older revision		Revision as of 17:53, 21 December 2014
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-	~~{{STRUCTURE_3w2y\| PDB=3w2y \| SCENE= }}~~	+	==Crystal structure of DNA uridine endonuclease Mth212 mutant W205S==
-	===Crystal structure of DNA uridine endonuclease Mth212 mutant W205S===	+	<StructureSection load='3w2y' size='340' side='right' caption='[[3w2y]], [[Resolution\|resolution]] 1.90Å' scene=''>
-		+	== Structural highlights ==
-	==~~About this Structure~~==	+	<table><tr><td colspan='2'>[[3w2y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Metth Metth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W2Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W2Y FirstGlance]. <br>
-	[[3w2y]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W2Y OCA].	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3w2x\|3w2x]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MTH212, MTH_212 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 METTH])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exodeoxyribonuclease_III Exodeoxyribonuclease III], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.11.2 3.1.11.2] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w2y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w2y RCSB], [http://www.ebi.ac.uk/pdbsum/3w2y PDBsum]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
	[[Category: Exodeoxyribonuclease III]]		[[Category: Exodeoxyribonuclease III]]
-	[[Category: Arai, R.]]	+	[[Category: Metth]]
-	[[Category: Shida, T.]]	+	[[Category: Arai, R]]
-	[[Category: Tabata, N.]]	+	[[Category: Shida, T]]
		+	[[Category: Tabata, N]]
	[[Category: Alpha/beta-sandwich]]		[[Category: Alpha/beta-sandwich]]
	[[Category: Dna binding]]		[[Category: Dna binding]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 13:42, 11 December 2013

2013-12-11T13:42:51Z

←Older revision		Revision as of 13:42, 11 December 2013
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-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_3w2y\| PDB=3w2y \| SCENE= }}
		+	===Crystal structure of DNA uridine endonuclease Mth212 mutant W205S===

-	~~The entry~~ 3w2y is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
-		+	[[3w2y]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W2Y OCA].
-	~~Authors~~: ~~Tabata~~, N., Shida, T., ~~Arai, R~~.	+	[[Category: Exodeoxyribonuclease III]]
-		+	[[Category: Arai, R.]]
-	~~Description~~: ~~Crystal structure of DNA uridine endonuclease Mth212 mutant W205S~~	+	[[Category: Shida, T.]]
		+	[[Category: Tabata, N.]]
		+	[[Category: Alpha/beta-sandwich]]
		+	[[Category: Dna binding]]
		+	[[Category: Hydrolase]]

OCA at 08:36, 2 January 2013

2013-01-02T08:36:18Z

←Older revision		Revision as of 08:36, 2 January 2013
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3w2y is ON HOLD	+	The entry 3w2y is ON HOLD until Paper Publication

	Authors: Tabata, N., Shida, T., Arai, R.		Authors: Tabata, N., Shida, T., Arai, R.

	Description: Crystal structure of DNA uridine endonuclease Mth212 mutant W205S		Description: Crystal structure of DNA uridine endonuclease Mth212 mutant W205S

OCA: Protected "3w2y" [edit=sysop:move=sysop]

2012-12-12T20:34:25Z

Protected "3w2y" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:34, 12 December 2012

OCA: New page: '''Unreleased structure''' The entry 3w2y is ON HOLD Authors: Tabata, N., Shida, T., Arai, R. Description: Crystal structure of DNA uridine endonuclease Mth212 mutant W205S

2012-12-12T20:34:24Z

New page: '''Unreleased structure''' The entry 3w2y is ON HOLD Authors: Tabata, N., Shida, T., Arai, R. Description: Crystal structure of DNA uridine endonuclease Mth212 mutant W205S

New page

'''Unreleased structure'''

The entry 3w2y is ON HOLD

Authors: Tabata, N., Shida, T., Arai, R.

Description: Crystal structure of DNA uridine endonuclease Mth212 mutant W205S