3wio - Revision history

OCA at 13:12, 8 November 2023

2023-11-08T13:12:13Z

←Older revision		Revision as of 13:12, 8 November 2023
Line 3:		Line 3:
	<StructureSection load='3wio' size='340' side='right'caption='[[3wio]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3wio' size='340' side='right'caption='[[3wio]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wio]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Japanese_rice Japanese rice~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WIO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WIO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3wio]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa_Japonica_Group Oryza sativa Japonica Group]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WIO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WIO FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=H3M:(5R)-5-HYDROXY-3-METHYLFURAN~~-2~~(5H)-ONE'>H3M</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[3vxk\|3vxk]]~~</~~div~~>~~</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=H3M:(5R)-5-HYDROXY-3-METHYLFURAN-2(5H)-ONE'>H3M</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">D14, D88, HTD2, LOC_Os03g10620, Os03g0203200 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39947 Japanese rice])</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wio OCA], [https://pdbe.org/3wio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wio RCSB], [https://www.ebi.ac.uk/pdbsum/3wio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wio ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wio OCA], [https://pdbe.org/3wio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wio RCSB], [https://www.ebi.ac.uk/pdbsum/3wio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wio ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/D14_ORYSJ D14_ORYSJ]] Involved in strigolactone signaling pathway. May function downstream of strigolactone synthesis, as a component of hormone signaling or as an enzyme that participates in the conversion of strigolactones to the bioactive form. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds.<ref>PMID:19542179</ref> <ref>PMID:23301669</ref>	+	[https://www.uniprot.org/uniprot/D14_ORYSJ D14_ORYSJ] Involved in strigolactone signaling pathway. May function downstream of strigolactone synthesis, as a component of hormone signaling or as an enzyme that participates in the conversion of strigolactones to the bioactive form. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds.<ref>PMID:19542179</ref> <ref>PMID:23301669</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Japanese rice]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hou, F]]	+	[[Category: Oryza sativa Japonica Group]]
-	[[Category: Miyakawa, T]]	+	[[Category: Hou F]]
-	[[Category: Qin, H M]]	+	[[Category: Miyakawa T]]
-	[[Category: Tanokura, M]]	+	[[Category: Qin H-M]]
-	[[Category: Xue, Y L]]	+	[[Category: Tanokura M]]
-	~~[[Category: Alpha/beta-hydrolase fold]]~~	+	[[Category: Xue Y-L]]
-	~~[[Category: Hydrolase~~]]	+

OCA at 05:37, 3 August 2022

2022-08-03T05:37:56Z

←Older revision		Revision as of 05:37, 3 August 2022
Line 1:		Line 1:

	==Crystal structure of OSD14 in complex with hydroxy D-ring==		==Crystal structure of OSD14 in complex with hydroxy D-ring==
-	<StructureSection load='3wio' size='340' side='right' caption='[[3wio]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='3wio' size='340' side='right'caption='[[3wio]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wio]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Japanese_rice Japanese rice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WIO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3WIO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3wio]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Japanese_rice Japanese rice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WIO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WIO FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H3M:(5R)-5-HYDROXY-3-METHYLFURAN-2(5H)-ONE'>H3M</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=H3M:(5R)-5-HYDROXY-3-METHYLFURAN-2(5H)-ONE'>H3M</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vxk\|3vxk]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3vxk\|3vxk]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">D14, D88, HTD2, LOC_Os03g10620, Os03g0203200 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39947 Japanese rice])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">D14, D88, HTD2, LOC_Os03g10620, Os03g0203200 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39947 Japanese rice])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3wio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wio OCA], [~~http~~://pdbe.org/3wio PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3wio RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3wio PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3wio ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wio OCA], [https://pdbe.org/3wio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wio RCSB], [https://www.ebi.ac.uk/pdbsum/3wio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wio ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/D14_ORYSJ D14_ORYSJ]] Involved in strigolactone signaling pathway. May function downstream of strigolactone synthesis, as a component of hormone signaling or as an enzyme that participates in the conversion of strigolactones to the bioactive form. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds.<ref>PMID:19542179</ref> <ref>PMID:23301669</ref>	+	[[https://www.uniprot.org/uniprot/D14_ORYSJ D14_ORYSJ]] Involved in strigolactone signaling pathway. May function downstream of strigolactone synthesis, as a component of hormone signaling or as an enzyme that participates in the conversion of strigolactones to the bioactive form. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds.<ref>PMID:19542179</ref> <ref>PMID:23301669</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Japanese rice]]		[[Category: Japanese rice]]
		+	[[Category: Large Structures]]
	[[Category: Hou, F]]		[[Category: Hou, F]]
	[[Category: Miyakawa, T]]		[[Category: Miyakawa, T]]

OCA at 10:03, 4 August 2016

2016-08-04T10:03:19Z

←Older revision		Revision as of 10:03, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of OSD14 in complex with hydroxy D-ring==		==Crystal structure of OSD14 in complex with hydroxy D-ring==
	<StructureSection load='3wio' size='340' side='right' caption='[[3wio]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3wio' size='340' side='right' caption='[[3wio]], [[Resolution\|resolution]] 2.10Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vxk\|3vxk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vxk\|3vxk]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">D14, D88, HTD2, LOC_Os03g10620, Os03g0203200 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39947 Japanese rice])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">D14, D88, HTD2, LOC_Os03g10620, Os03g0203200 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39947 Japanese rice])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wio RCSB], [http://www.ebi.ac.uk/pdbsum/3wio PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wio OCA], [http://pdbe.org/3wio PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wio RCSB], [http://www.ebi.ac.uk/pdbsum/3wio PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wio ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3wio" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:08, 25 December 2014

2014-12-25T08:08:59Z

←Older revision		Revision as of 08:08, 25 December 2014
Line 2:		Line 2:
	<StructureSection load='3wio' size='340' side='right' caption='[[3wio]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3wio' size='340' side='right' caption='[[3wio]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wio]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Japanese_rice Japanese rice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WIO OCA]. <br>	+	<table><tr><td colspan='2'>[[3wio]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Japanese_rice Japanese rice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WIO FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H3M:(5R)-5-HYDROXY-3-METHYLFURAN-2(5H)-ONE'>H3M</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H3M:(5R)-5-HYDROXY-3-METHYLFURAN-2(5H)-ONE'>H3M</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vxk\|3vxk]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vxk\|3vxk]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">D14, D88, HTD2, LOC_Os03g10620, Os03g0203200 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39947 Japanese rice])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">D14, D88, HTD2, LOC_Os03g10620, Os03g0203200 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39947 Japanese rice])</td></tr>
-	<tr~~><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class~~='~~plainlinks~~'~~>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wio RCSB], [http://www.ebi.ac.uk/pdbsum/3wio PDBsum]</span></td></tr>
-	~~<tr~~><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wio RCSB], [http://www.ebi.ac.uk/pdbsum/3wio PDBsum]</span></td></tr>	+	</table>
-	<table>	+	== Function ==
		+	[[http://www.uniprot.org/uniprot/D14_ORYSJ D14_ORYSJ]] Involved in strigolactone signaling pathway. May function downstream of strigolactone synthesis, as a component of hormone signaling or as an enzyme that participates in the conversion of strigolactones to the bioactive form. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds.<ref>PMID:19542179</ref> <ref>PMID:23301669</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 15:		Line 16:
	Molecular mechanism of strigolactone perception by DWARF14.,Nakamura H, Xue YL, Miyakawa T, Hou F, Qin HM, Fukui K, Shi X, Ito E, Ito S, Park SH, Miyauchi Y, Asano A, Totsuka N, Ueda T, Tanokura M, Asami T Nat Commun. 2013;4:2613. doi: 10.1038/ncomms3613. PMID:24131983<ref>PMID:24131983</ref>		Molecular mechanism of strigolactone perception by DWARF14.,Nakamura H, Xue YL, Miyakawa T, Hou F, Qin HM, Fukui K, Shi X, Ito E, Ito S, Park SH, Miyauchi Y, Asano A, Totsuka N, Ueda T, Tanokura M, Asami T Nat Commun. 2013;4:2613. doi: 10.1038/ncomms3613. PMID:24131983<ref>PMID:24131983</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 22:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Japanese rice]]		[[Category: Japanese rice]]
-	[[Category: Hou, F.]]	+	[[Category: Hou, F]]
-	[[Category: Miyakawa, T.]]	+	[[Category: Miyakawa, T]]
-	[[Category: Qin, H M.]]	+	[[Category: Qin, H M]]
-	[[Category: Tanokura, M.]]	+	[[Category: Tanokura, M]]
-	[[Category: Xue, Y L.]]	+	[[Category: Xue, Y L]]
	[[Category: Alpha/beta-hydrolase fold]]		[[Category: Alpha/beta-hydrolase fold]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 09:37, 1 May 2014

2014-05-01T09:37:08Z

←Older revision		Revision as of 09:37, 1 May 2014
Line 2:		Line 2:
	<StructureSection load='3wio' size='340' side='right' caption='[[3wio]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3wio' size='340' side='right' caption='[[3wio]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	[[3wio]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Japanese_rice Japanese rice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WIO OCA]. <br>	+	<table><tr><td colspan='2'>[[3wio]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Japanese_rice Japanese rice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WIO OCA]. <br>
-	<b>[[Ligand\|Ligands:]]</b> <scene name='pdbligand=H3M:(5R)-5-HYDROXY-3-METHYLFURAN-2(5H)-ONE'>H3M</scene><br>	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H3M:(5R)-5-HYDROXY-3-METHYLFURAN-2(5H)-ONE'>H3M</scene><br>
-	<b>[[Related_structure\|Related:]]</b> [[3vxk\|3vxk]]<br>	+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vxk\|3vxk]]</td></tr>
-	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>	+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">D14, D88, HTD2, LOC_Os03g10620, Os03g0203200 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39947 Japanese rice])</td></tr>
-	<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wio RCSB], [http://www.ebi.ac.uk/pdbsum/3wio PDBsum]</span><br>	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wio RCSB], [http://www.ebi.ac.uk/pdbsum/3wio PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
	Strigolactones (SLs) are phytohormones that inhibit shoot branching and function in the rhizospheric communication with symbiotic fungi and parasitic weeds. An alpha/beta-hydrolase protein, DWARF14 (D14), has been recognized to be an essential component of plant SL signalling, although its precise function remains unknown. Here we present the SL-dependent interaction of D14 with a gibberellin signalling repressor SLR1 and a possible mechanism of phytohormone perception in D14-mediated SL signalling. D14 functions as a cleavage enzyme of SLs, and the cleavage reaction induces the interaction with SLR1. The crystal structure of D14 shows that 5-hydroxy-3-methylbutenolide (D-OH), which is a reaction product of SLs, is trapped in the catalytic cavity of D14 to form an altered surface. The D14 residues recognizing D-OH are critical for the SL-dependent D14-SLR1 interaction. These results provide new insight into crosstalk between gibberellin and SL signalling pathways.		Strigolactones (SLs) are phytohormones that inhibit shoot branching and function in the rhizospheric communication with symbiotic fungi and parasitic weeds. An alpha/beta-hydrolase protein, DWARF14 (D14), has been recognized to be an essential component of plant SL signalling, although its precise function remains unknown. Here we present the SL-dependent interaction of D14 with a gibberellin signalling repressor SLR1 and a possible mechanism of phytohormone perception in D14-mediated SL signalling. D14 functions as a cleavage enzyme of SLs, and the cleavage reaction induces the interaction with SLR1. The crystal structure of D14 shows that 5-hydroxy-3-methylbutenolide (D-OH), which is a reaction product of SLs, is trapped in the catalytic cavity of D14 to form an altered surface. The D14 residues recognizing D-OH are critical for the SL-dependent D14-SLR1 interaction. These results provide new insight into crosstalk between gibberellin and SL signalling pathways.
Line 13:		Line 16:

	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>		From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:11, 30 April 2014

2014-04-30T10:11:19Z

←Older revision		Revision as of 10:11, 30 April 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	[[3wio]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Japanese_rice Japanese rice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WIO OCA]. <br>		[[3wio]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Japanese_rice Japanese rice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WIO OCA]. <br>
-	<b>Related:</b> [[3vxk\|3vxk]]<br>	+	<b>[[Ligand\|Ligands:]]</b> <scene name='pdbligand=H3M:(5R)-5-HYDROXY-3-METHYLFURAN-2(5H)-ONE'>H3M</scene><br>
		+	<b>[[Related_structure\|Related:]]</b> [[3vxk\|3vxk]]<br>
	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>		<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
		+	<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wio RCSB], [http://www.ebi.ac.uk/pdbsum/3wio PDBsum]</span><br>
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
	Strigolactones (SLs) are phytohormones that inhibit shoot branching and function in the rhizospheric communication with symbiotic fungi and parasitic weeds. An alpha/beta-hydrolase protein, DWARF14 (D14), has been recognized to be an essential component of plant SL signalling, although its precise function remains unknown. Here we present the SL-dependent interaction of D14 with a gibberellin signalling repressor SLR1 and a possible mechanism of phytohormone perception in D14-mediated SL signalling. D14 functions as a cleavage enzyme of SLs, and the cleavage reaction induces the interaction with SLR1. The crystal structure of D14 shows that 5-hydroxy-3-methylbutenolide (D-OH), which is a reaction product of SLs, is trapped in the catalytic cavity of D14 to form an altered surface. The D14 residues recognizing D-OH are critical for the SL-dependent D14-SLR1 interaction. These results provide new insight into crosstalk between gibberellin and SL signalling pathways.		Strigolactones (SLs) are phytohormones that inhibit shoot branching and function in the rhizospheric communication with symbiotic fungi and parasitic weeds. An alpha/beta-hydrolase protein, DWARF14 (D14), has been recognized to be an essential component of plant SL signalling, although its precise function remains unknown. Here we present the SL-dependent interaction of D14 with a gibberellin signalling repressor SLR1 and a possible mechanism of phytohormone perception in D14-mediated SL signalling. D14 functions as a cleavage enzyme of SLs, and the cleavage reaction induces the interaction with SLR1. The crystal structure of D14 shows that 5-hydroxy-3-methylbutenolide (D-OH), which is a reaction product of SLs, is trapped in the catalytic cavity of D14 to form an altered surface. The D14 residues recognizing D-OH are critical for the SL-dependent D14-SLR1 interaction. These results provide new insight into crosstalk between gibberellin and SL signalling pathways.

OCA at 05:24, 30 April 2014

2014-04-30T05:24:51Z

←Older revision		Revision as of 05:24, 30 April 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3wio\| PDB=3wio \| SCENE= }}~~	+	==Crystal structure of OSD14 in complex with hydroxy D-ring==
-	===Crystal structure of OSD14 in complex with hydroxy D-ring===	+	<StructureSection load='3wio' size='340' side='right' caption='[[3wio]], [[Resolution\|resolution]] 2.10Å' scene=''>
		+	== Structural highlights ==
		+	[[3wio]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Japanese_rice Japanese rice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WIO OCA]. <br>
		+	<b>Related:</b> [[3vxk\|3vxk]]<br>
		+	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
		+	== Publication Abstract from PubMed ==
		+	Strigolactones (SLs) are phytohormones that inhibit shoot branching and function in the rhizospheric communication with symbiotic fungi and parasitic weeds. An alpha/beta-hydrolase protein, DWARF14 (D14), has been recognized to be an essential component of plant SL signalling, although its precise function remains unknown. Here we present the SL-dependent interaction of D14 with a gibberellin signalling repressor SLR1 and a possible mechanism of phytohormone perception in D14-mediated SL signalling. D14 functions as a cleavage enzyme of SLs, and the cleavage reaction induces the interaction with SLR1. The crystal structure of D14 shows that 5-hydroxy-3-methylbutenolide (D-OH), which is a reaction product of SLs, is trapped in the catalytic cavity of D14 to form an altered surface. The D14 residues recognizing D-OH are critical for the SL-dependent D14-SLR1 interaction. These results provide new insight into crosstalk between gibberellin and SL signalling pathways.

-	~~==Function==~~	+	Molecular mechanism of strigolactone perception by DWARF14.,Nakamura H, Xue YL, Miyakawa T, Hou F, Qin HM, Fukui K, Shi X, Ito E, Ito S, Park SH, Miyauchi Y, Asano A, Totsuka N, Ueda T, Tanokura M, Asami T Nat Commun. 2013;4:2613. doi: 10.1038/ncomms3613. PMID:24131983<ref>PMID:24131983</ref>
-	~~[[http~~:~~//www~~.~~uniprot~~.~~org~~/~~uniprot/D14_ORYSJ D14_ORYSJ]] Involved in strigolactone signaling pathway~~. May function downstream of strigolactone synthesis, as a component of hormone signaling or as an enzyme that participates in the conversion of strigolactones to the bioactive form. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds.<ref>PMID:~~19542179</ref>~~ <ref>PMID:~~23301669~~</ref>	+

-	~~==About this Structure==~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-	~~[[3wio]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bionectria_wenpingii Bionectria wenpingii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WIO OCA]~~.	+	== References ==
-		+	<references/>
-	==~~Reference~~==	+	__TOC__
-	<references ~~group="xtra"~~/><~~references~~/>	+	</StructureSection>
-	[[Category: ~~Bionectria wenpingii~~]]	+	[[Category: Japanese rice]]
	[[Category: Hou, F.]]		[[Category: Hou, F.]]
	[[Category: Miyakawa, T.]]		[[Category: Miyakawa, T.]]

OCA at 06:50, 23 October 2013

2013-10-23T06:50:39Z

←Older revision		Revision as of 06:50, 23 October 2013
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_3wio\| PDB=3wio \| SCENE= }}
		+	===Crystal structure of OSD14 in complex with hydroxy D-ring===

-	~~The entry 3wio is ON HOLD~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/D14_ORYSJ D14_ORYSJ]] Involved in strigolactone signaling pathway. May function downstream of strigolactone synthesis, as a component of hormone signaling or as an enzyme that participates in the conversion of strigolactones to the bioactive form. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds.<ref>PMID:19542179</ref> <ref>PMID:23301669</ref>

-	~~Authors~~: ~~Xue, Y~~.-L.~~, Miyakawa, T~~.~~, Hou, F~~.~~, Qin, H~~.-M.~~, Tanokura, M~~.	+	==About this Structure==
		+	[[3wio]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bionectria_wenpingii Bionectria wenpingii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WIO OCA].

-	~~Description~~: ~~Crystal structure of OSD14 in complex with hydroxy D~~-~~ring~~	+	==Reference==
		+	<references group="xtra"/><references/>
		+	[[Category: Bionectria wenpingii]]
		+	[[Category: Hou, F.]]
		+	[[Category: Miyakawa, T.]]
		+	[[Category: Qin, H M.]]
		+	[[Category: Tanokura, M.]]
		+	[[Category: Xue, Y L.]]
		+	[[Category: Alpha/beta-hydrolase fold]]
		+	[[Category: Hydrolase]]

OCA at 05:23, 10 October 2013

2013-10-10T05:23:54Z

←Older revision		Revision as of 05:23, 10 October 2013
Line 5:		Line 5:
	Authors: Xue, Y.-L., Miyakawa, T., Hou, F., Qin, H.-M., Tanokura, M.		Authors: Xue, Y.-L., Miyakawa, T., Hou, F., Qin, H.-M., Tanokura, M.

-	Description: ~~CRYSTAL STRUCTURE OF~~ OSD14 ~~IN COMPLEX WITH HYDROXY~~ D-~~RING~~	+	Description: Crystal structure of OSD14 in complex with hydroxy D-ring

OCA: Protected "3wio" [edit=sysop:move=sysop]

2013-10-02T06:28:59Z

Protected "3wio" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:28, 2 October 2013