3zjm - Revision history

OCA at 11:03, 20 December 2023

2023-12-20T11:03:23Z

←Older revision		Revision as of 11:03, 20 December 2023
Line 3:		Line 3:
	<StructureSection load='3zjm' size='340' side='right'caption='[[3zjm]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='3zjm' size='340' side='right'caption='[[3zjm]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zjm]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_35395 Atcc 35395~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZJM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZJM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zjm]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_acetivorans Methanosarcina acetivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZJM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZJM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3zjh\|3zjh]], [[3zji\|3zji]], [[3zjj\|3zjj]], [[3zjl\|3zjl]], [[3zjn\|3zjn]], [[3zjo\|3zjo]], [[3zjp\|3zjp]], [[3zjq\|3zjq]], [[3zjr\|3zjr]], [[3zjs\|3zjs]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zjm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zjm OCA], [https://pdbe.org/3zjm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zjm RCSB], [https://www.ebi.ac.uk/pdbsum/3zjm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zjm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zjm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zjm OCA], [https://pdbe.org/3zjm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zjm RCSB], [https://www.ebi.ac.uk/pdbsum/3zjm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zjm ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q8TLY9_METAC Q8TLY9_METAC]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 35395]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ascenzi, P]]	+	[[Category: Methanosarcina acetivorans]]
-	[[Category: Aste, E]]	+	[[Category: Ascenzi P]]
-	[[Category: Bolognesi, M]]	+	[[Category: Aste E]]
-	[[Category: Ciaccio, C]]	+	[[Category: Bolognesi M]]
-	[[Category: Coletta, M]]	+	[[Category: Ciaccio C]]
-	[[Category: Dewilde, S]]	+	[[Category: Coletta M]]
-	[[Category: Donne, J]]	+	[[Category: Dewilde S]]
-	[[Category: Moens, L]]	+	[[Category: Donne J]]
-	[[Category: Nardini, M]]	+	[[Category: Moens L]]
-	[[Category: Pesce, A]]	+	[[Category: Nardini M]]
-	[[Category: Tilleman, L]]	+	[[Category: Pesce A]]
-	[[Category: Viappiani, C]]	+	[[Category: Tilleman L]]
-	~~[[Category: Haem-distal site mutation]]~~	+	[[Category: Viappiani C]]
-	~~[[Category: Iron-binding protein~~]]	+

OCA at 05:48, 10 August 2022

2022-08-10T05:48:42Z

←Older revision		Revision as of 05:48, 10 August 2022
Line 1:		Line 1:

	==Ile(149)G11Phe mutation of M.acetivorans protoglobin in complex with cyanide==		==Ile(149)G11Phe mutation of M.acetivorans protoglobin in complex with cyanide==
-	<StructureSection load='3zjm' size='340' side='right' caption='[[3zjm]], [[Resolution\|resolution]] 1.50Å' scene=''>	+	<StructureSection load='3zjm' size='340' side='right'caption='[[3zjm]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zjm]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_35395 Atcc 35395]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZJM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ZJM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zjm]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_35395 Atcc 35395]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZJM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZJM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zjh\|3zjh]], [[3zji\|3zji]], [[3zjj\|3zjj]], [[3zjl\|3zjl]], [[3zjn\|3zjn]], [[3zjo\|3zjo]], [[3zjp\|3zjp]], [[3zjq\|3zjq]], [[3zjr\|3zjr]], [[3zjs\|3zjs]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3zjh\|3zjh]], [[3zji\|3zji]], [[3zjj\|3zjj]], [[3zjl\|3zjl]], [[3zjn\|3zjn]], [[3zjo\|3zjo]], [[3zjp\|3zjp]], [[3zjq\|3zjq]], [[3zjr\|3zjr]], [[3zjs\|3zjs]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3zjm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zjm OCA], [~~http~~://pdbe.org/3zjm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3zjm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3zjm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3zjm ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zjm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zjm OCA], [https://pdbe.org/3zjm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zjm RCSB], [https://www.ebi.ac.uk/pdbsum/3zjm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zjm ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 22:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 35395]]		[[Category: Atcc 35395]]
		+	[[Category: Large Structures]]
	[[Category: Ascenzi, P]]		[[Category: Ascenzi, P]]
	[[Category: Aste, E]]		[[Category: Aste, E]]

OCA at 16:47, 27 February 2019

2019-02-27T16:47:51Z

←Older revision		Revision as of 16:47, 27 February 2019
Line 3:		Line 3:
	<StructureSection load='3zjm' size='340' side='right' caption='[[3zjm]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='3zjm' size='340' side='right' caption='[[3zjm]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zjm]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZJM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZJM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zjm]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35395 Atcc 35395]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZJM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZJM FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zjh\|3zjh]], [[3zji\|3zji]], [[3zjj\|3zjj]], [[3zjl\|3zjl]], [[3zjn\|3zjn]], [[3zjo\|3zjo]], [[3zjp\|3zjp]], [[3zjq\|3zjq]], [[3zjr\|3zjr]], [[3zjs\|3zjs]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zjh\|3zjh]], [[3zji\|3zji]], [[3zjj\|3zjj]], [[3zjl\|3zjl]], [[3zjn\|3zjn]], [[3zjo\|3zjo]], [[3zjp\|3zjp]], [[3zjq\|3zjq]], [[3zjr\|3zjr]], [[3zjs\|3zjs]]</td></tr>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 35395]]
	[[Category: Ascenzi, P]]		[[Category: Ascenzi, P]]
	[[Category: Aste, E]]		[[Category: Aste, E]]

OCA at 14:17, 22 December 2016

2016-12-22T14:17:58Z

←Older revision		Revision as of 14:17, 22 December 2016
Line 3:		Line 3:
	<StructureSection load='3zjm' size='340' side='right' caption='[[3zjm]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='3zjm' size='340' side='right' caption='[[3zjm]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zjm]] is a 3 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Atcc_35395 Atcc 35395]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZJM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZJM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zjm]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZJM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZJM FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zjh\|3zjh]], [[3zji\|3zji]], [[3zjj\|3zjj]], [[3zjl\|3zjl]], [[3zjn\|3zjn]], [[3zjo\|3zjo]], [[3zjp\|3zjp]], [[3zjq\|3zjq]], [[3zjr\|3zjr]], [[3zjs\|3zjs]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zjh\|3zjh]], [[3zji\|3zji]], [[3zjj\|3zjj]], [[3zjl\|3zjl]], [[3zjn\|3zjn]], [[3zjo\|3zjo]], [[3zjp\|3zjp]], [[3zjq\|3zjq]], [[3zjr\|3zjr]], [[3zjs\|3zjs]]</td></tr>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 35395]]
	[[Category: Ascenzi, P]]		[[Category: Ascenzi, P]]
	[[Category: Aste, E]]		[[Category: Aste, E]]
Line 28:		Line 27:
	[[Category: Coletta, M]]		[[Category: Coletta, M]]
	[[Category: Dewilde, S]]		[[Category: Dewilde, S]]
-	[[Category: Donne , J]]	+	[[Category: Donne, J]]
	[[Category: Moens, L]]		[[Category: Moens, L]]
	[[Category: Nardini, M]]		[[Category: Nardini, M]]

OCA at 12:44, 4 August 2016

2016-08-04T12:44:47Z

←Older revision		Revision as of 12:44, 4 August 2016
Line 1:		Line 1:
		+
	==Ile(149)G11Phe mutation of M.acetivorans protoglobin in complex with cyanide==		==Ile(149)G11Phe mutation of M.acetivorans protoglobin in complex with cyanide==
	<StructureSection load='3zjm' size='340' side='right' caption='[[3zjm]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='3zjm' size='340' side='right' caption='[[3zjm]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3zjm]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Methanosarcina_acetivorans Methanosarcina acetivorans~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZJM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZJM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3zjm]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35395 Atcc 35395]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZJM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZJM FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zjh\|3zjh]], [[3zji\|3zji]], [[3zjj\|3zjj]], [[3zjl\|3zjl]], [[3zjn\|3zjn]], [[3zjo\|3zjo]], [[3zjp\|3zjp]], [[3zjq\|3zjq]], [[3zjr\|3zjr]], [[3zjs\|3zjs]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zjh\|3zjh]], [[3zji\|3zji]], [[3zjj\|3zjj]], [[3zjl\|3zjl]], [[3zjn\|3zjn]], [[3zjo\|3zjo]], [[3zjp\|3zjp]], [[3zjq\|3zjq]], [[3zjr\|3zjr]], [[3zjs\|3zjs]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zjm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zjm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zjm RCSB], [http://www.ebi.ac.uk/pdbsum/3zjm PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zjm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zjm OCA], [http://pdbe.org/3zjm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zjm RCSB], [http://www.ebi.ac.uk/pdbsum/3zjm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zjm ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3zjm" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Methanosarcina acetivorans~~]]	+	[[Category: Atcc 35395]]
	[[Category: Ascenzi, P]]		[[Category: Ascenzi, P]]
	[[Category: Aste, E]]		[[Category: Aste, E]]

OCA at 09:38, 21 December 2014

2014-12-21T09:38:59Z

←Older revision		Revision as of 09:38, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3zjm\| PDB=3zjm \| SCENE= }}~~	+	==Ile(149)G11Phe mutation of M.acetivorans protoglobin in complex with cyanide==
-	===Ile(149)G11Phe mutation of M.acetivorans protoglobin in complex with cyanide===	+	<StructureSection load='3zjm' size='340' side='right' caption='[[3zjm]], [[Resolution\|resolution]] 1.50Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23776624}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3zjm]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanosarcina_acetivorans Methanosarcina acetivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZJM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZJM FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3zjh\|3zjh]], [[3zji\|3zji]], [[3zjj\|3zjj]], [[3zjl\|3zjl]], [[3zjn\|3zjn]], [[3zjo\|3zjo]], [[3zjp\|3zjp]], [[3zjq\|3zjq]], [[3zjr\|3zjr]], [[3zjs\|3zjs]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zjm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zjm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zjm RCSB], [http://www.ebi.ac.uk/pdbsum/3zjm PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Protoglobin from Methanosarcina acetivorans C2A (MaPgb), a strictly anaerobic methanogenic Archaea, is a dimeric haem-protein whose biological role is still unknown. As other globins, protoglobin can bind O2, CO and NO reversibly in vitro, but it displays specific functional and structural properties within members of the hemoglobin superfamily. CO binding to and dissociation from the haem occurs through biphasic kinetics, which arise from binding to (and dissociation from) two distinct tertiary states in a ligation-dependent equilibrium. From the structural viewpoint, protoglobin-specific loops and a N-terminal extension of 20 residues completely bury the haem within the protein matrix. Thus, access of small ligand molecules to the haem is granted by two apolar tunnels, not common to other globins, which reach the haem distal site from locations at the B/G and B/E helix interfaces. Here, the roles played by residues Trp(60)B9, Tyr(61)B10 and Phe(93)E11 in ligand recognition and stabilization are analyzed, through crystallographic investigations on the ferric protein and on selected mutants. Specifically, protein structures are reported for protoglobin complexes with cyanide, with azide (also in the presence of Xenon), and with more bulky ligands, such as imidazole and nicotinamide. Values of the rate constant for cyanide dissociation from ferric MaPgb-cyanide complexes have been correlated to hydrogen bonds provided by Trp(60)B9 and Tyr(61)B10 that stabilize the haem-Fe(III)-bound cyanide. We show that protoglobin can strikingly reshape, in a ligand-dependent way, the haem distal site, where Phe(93)E11 acts as ligand sensor and controls accessibility to the haem through the tunnel system by modifying the conformation of Trp(60)B9.

-	~~==About this~~ Structure==	+	Structure and Haem-Distal Site Plasticity in Methanosarcina acetivorans Protoglobin.,Pesce A, Tilleman L, Donne J, Aste E, Ascenzi P, Ciaccio C, Coletta M, Moens L, Viappiani C, Dewilde S, Bolognesi M, Nardini M PLoS One. 2013 Jun 12;8(6):e66144. doi: 10.1371/journal.pone.0066144. Print 2013. PMID:23776624<ref>PMID:23776624</ref>
-	~~[[3zjm]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanosarcina_acetivorans~~ Methanosarcina acetivorans]. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3ZJM OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:023776624</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Methanosarcina acetivorans]]		[[Category: Methanosarcina acetivorans]]
-	[[Category: Ascenzi, P.]]	+	[[Category: Ascenzi, P]]
-	[[Category: Aste, E.]]	+	[[Category: Aste, E]]
-	[[Category: Bolognesi, M.]]	+	[[Category: Bolognesi, M]]
-	[[Category: Ciaccio, C.]]	+	[[Category: Ciaccio, C]]
-	[[Category: Coletta, M.]]	+	[[Category: Coletta, M]]
-	[[Category: Dewilde, S.]]	+	[[Category: Dewilde, S]]
-	[[Category: Donne , J.]]	+	[[Category: Donne , J]]
-	[[Category: Moens, L.]]	+	[[Category: Moens, L]]
-	[[Category: Nardini, M.]]	+	[[Category: Nardini, M]]
-	[[Category: Pesce, A.]]	+	[[Category: Pesce, A]]
-	[[Category: Tilleman, L.]]	+	[[Category: Tilleman, L]]
-	[[Category: Viappiani, C.]]	+	[[Category: Viappiani, C]]
	[[Category: Haem-distal site mutation]]		[[Category: Haem-distal site mutation]]
	[[Category: Iron-binding protein]]		[[Category: Iron-binding protein]]

OCA at 09:53, 30 June 2013

2013-06-30T09:53:46Z

←Older revision		Revision as of 09:53, 30 June 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_3zjm\| PDB=3zjm \| SCENE= }}
		+	===Ile(149)G11Phe mutation of M.acetivorans protoglobin in complex with cyanide===
		+	{{ABSTRACT_PUBMED_23776624}}

-	~~The entry~~ 3zjm is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
		+	[[3zjm]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanosarcina_acetivorans Methanosarcina acetivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZJM OCA].

-	~~Authors~~: ~~Pesce~~, A.~~, Tilleman, L., Donne', J.,~~ Aste, E., ~~Ascenzi, P~~., Ciaccio, C., Coletta, M., Moens, L., ~~Viappiani, C~~., ~~Dewilde, S~~., ~~Bolognesi, M~~., ~~Nardini, M~~.	+	==Reference==
-		+	<ref group="xtra">PMID:023776624</ref><references group="xtra"/><references/>
-	~~Description~~: ~~Ile(149)G11Phe mutation of M.acetivorans protoglobin in complex with cyanide~~	+	[[Category: Methanosarcina acetivorans]]
		+	[[Category: Ascenzi, P.]]
		+	[[Category: Aste, E.]]
		+	[[Category: Bolognesi, M.]]
		+	[[Category: Ciaccio, C.]]
		+	[[Category: Coletta, M.]]
		+	[[Category: Dewilde, S.]]
		+	[[Category: Donne , J.]]
		+	[[Category: Moens, L.]]
		+	[[Category: Nardini, M.]]
		+	[[Category: Pesce, A.]]
		+	[[Category: Tilleman, L.]]
		+	[[Category: Viappiani, C.]]
		+	[[Category: Haem-distal site mutation]]
		+	[[Category: Iron-binding protein]]

OCA at 06:54, 2 May 2013

2013-05-02T06:54:58Z

←Older revision		Revision as of 06:54, 2 May 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3zjm is ON HOLD	+	The entry 3zjm is ON HOLD until Paper Publication

	Authors: Pesce, A., Tilleman, L., Donne', J., Aste, E., Ascenzi, P., Ciaccio, C., Coletta, M., Moens, L., Viappiani, C., Dewilde, S., Bolognesi, M., Nardini, M.		Authors: Pesce, A., Tilleman, L., Donne', J., Aste, E., Ascenzi, P., Ciaccio, C., Coletta, M., Moens, L., Viappiani, C., Dewilde, S., Bolognesi, M., Nardini, M.

	Description: Ile(149)G11Phe mutation of M.acetivorans protoglobin in complex with cyanide		Description: Ile(149)G11Phe mutation of M.acetivorans protoglobin in complex with cyanide

OCA: Protected "3zjm" [edit=sysop:move=sysop]

2013-01-23T10:58:17Z

Protected "3zjm" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:58, 23 January 2013

OCA: New page: '''Unreleased structure''' The entry 3zjm is ON HOLD Authors: Pesce, A., Tilleman, L., Donne', J., Aste, E., Ascenzi, P., Ciaccio, C., Coletta, M., Moens, L., Viappiani, C., Dewilde, S....

2013-01-23T10:58:15Z

New page: '''Unreleased structure''' The entry 3zjm is ON HOLD Authors: Pesce, A., Tilleman, L., Donne', J., Aste, E., Ascenzi, P., Ciaccio, C., Coletta, M., Moens, L., Viappiani, C., Dewilde, S....

New page

'''Unreleased structure'''

The entry 3zjm is ON HOLD

Authors: Pesce, A., Tilleman, L., Donne', J., Aste, E., Ascenzi, P., Ciaccio, C., Coletta, M., Moens, L., Viappiani, C., Dewilde, S., Bolognesi, M., Nardini, M.

Description: Ile(149)G11Phe mutation of M.acetivorans protoglobin in complex with cyanide