4a15 - Revision history

OCA at 11:17, 20 December 2023

2023-12-20T11:17:55Z

←Older revision		Revision as of 11:17, 20 December 2023
Line 3:		Line 3:
	<StructureSection load='4a15' size='340' side='right'caption='[[4a15]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='4a15' size='340' side='right'caption='[[4a15]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4a15]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"thermoplasma_acidophila"_(sic)_darland_et_al._1970 "thermoplasma acidophila" (sic) darland et al. 1970~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A15 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A15 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4a15]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A15 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A15 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>~~, ~~<scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[2vsf\|2vsf]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:</b></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a15 OCA], [https://pdbe.org/4a15 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a15 RCSB], [https://www.ebi.ac.uk/pdbsum/4a15 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a15 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a15 OCA], [https://pdbe.org/4a15 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a15 RCSB], [https://www.ebi.ac.uk/pdbsum/4a15 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a15 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/XPD_THEAC XPD_THEAC]] ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA (By similarity).	+	[https://www.uniprot.org/uniprot/XPD_THEAC XPD_THEAC] ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 27:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: DNA helicase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Kisker, C~~]]	+	[[Category: Thermoplasma acidophilum]]
-	[[Category: ~~Kuper, J]]~~	+	[[Category: Kisker C]]
-	~~[[Category: Michels, G]]~~	+	[[Category: Kuper J]]
-	~~[[Category: Wolski, S~~ C]]	+	[[Category: Michels G]]
-	[[Category: ~~Helicase~~]]	+	[[Category: Wolski SC]]
-	[[Category: ~~Hydrolase~~]]	+
-	[[Category: ~~Nucleotide excision repair~~]]	+

OCA at 07:38, 18 August 2022

2022-08-18T07:38:21Z

←Older revision		Revision as of 07:38, 18 August 2022
Line 1:		Line 1:

	==Crystal structure of an XPD DNA complex==		==Crystal structure of an XPD DNA complex==
-	<StructureSection load='4a15' size='340' side='right' caption='[[4a15]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='4a15' size='340' side='right'caption='[[4a15]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4a15]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"thermoplasma_acidophila"_(sic)_darland_et_al._1970 "thermoplasma acidophila" (sic) darland et al. 1970]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A15 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4A15 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4a15]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"thermoplasma_acidophila"_(sic)_darland_et_al._1970 "thermoplasma acidophila" (sic) darland et al. 1970]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A15 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A15 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vsf\|2vsf]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2vsf\|2vsf]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4a15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a15 OCA], [~~http~~://pdbe.org/4a15 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4a15 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4a15 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4a15 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a15 OCA], [https://pdbe.org/4a15 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a15 RCSB], [https://www.ebi.ac.uk/pdbsum/4a15 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a15 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/XPD_THEAC XPD_THEAC]] ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA (By similarity).	+	[[https://www.uniprot.org/uniprot/XPD_THEAC XPD_THEAC]] ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:

	==See Also==		==See Also==
-	*[[Helicase\|Helicase]]	+	*[[Helicase 3D structures\|Helicase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 28:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: DNA helicase]]		[[Category: DNA helicase]]
		+	[[Category: Large Structures]]
	[[Category: Kisker, C]]		[[Category: Kisker, C]]
	[[Category: Kuper, J]]		[[Category: Kuper, J]]

OCA at 11:57, 4 August 2016

2016-08-04T11:57:10Z

←Older revision		Revision as of 11:57, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of an XPD DNA complex==		==Crystal structure of an XPD DNA complex==
	<StructureSection load='4a15' size='340' side='right' caption='[[4a15]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='4a15' size='340' side='right' caption='[[4a15]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4a15]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermoplasma_acidophilum Thermoplasma acidophilum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A15 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A15 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4a15]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"thermoplasma_acidophila"_(sic)_darland_et_al._1970 "thermoplasma acidophila" (sic) darland et al. 1970]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A15 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A15 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vsf\|2vsf]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vsf\|2vsf]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a15 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a15 RCSB], [http://www.ebi.ac.uk/pdbsum/4a15 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a15 OCA], [http://pdbe.org/4a15 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4a15 RCSB], [http://www.ebi.ac.uk/pdbsum/4a15 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4a15 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4a15" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Helicase\|Helicase]]
	== References ==		== References ==
	<references/>		<references/>
Line 23:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: DNA helicase]]		[[Category: DNA helicase]]
-	[[Category: Thermoplasma acidophilum]]
	[[Category: Kisker, C]]		[[Category: Kisker, C]]
	[[Category: Kuper, J]]		[[Category: Kuper, J]]

OCA at 14:13, 24 December 2014

2014-12-24T14:13:36Z

←Older revision		Revision as of 14:13, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4a15]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A15 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A15 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4a15]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A15 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A15 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vsf\|2vsf]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vsf\|2vsf]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a15 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a15 RCSB], [http://www.ebi.ac.uk/pdbsum/4a15 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a15 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a15 RCSB], [http://www.ebi.ac.uk/pdbsum/4a15 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/XPD_THEAC XPD_THEAC]] ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 24:
	[[Category: DNA helicase]]		[[Category: DNA helicase]]
	[[Category: Thermoplasma acidophilum]]		[[Category: Thermoplasma acidophilum]]
-	[[Category: Kisker, C.]]	+	[[Category: Kisker, C]]
-	[[Category: Kuper, J.]]	+	[[Category: Kuper, J]]
-	[[Category: Michels, G.]]	+	[[Category: Michels, G]]
-	[[Category: Wolski, S C.]]	+	[[Category: Wolski, S C]]
	[[Category: Helicase]]		[[Category: Helicase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Nucleotide excision repair]]		[[Category: Nucleotide excision repair]]

OCA at 09:25, 11 June 2014

2014-06-11T09:25:07Z

←Older revision		Revision as of 09:25, 11 June 2014
Line 1:		Line 1:
-	[[~~Image:~~4a15.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of an XPD DNA complex==
		+	<StructureSection load='4a15' size='340' side='right' caption='[[4a15]], [[Resolution\|resolution]] 2.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4a15]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A15 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A15 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vsf\|2vsf]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a15 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a15 RCSB], [http://www.ebi.ac.uk/pdbsum/4a15 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The XPD protein is a vital subunit of the general transcription factor TFIIH which is not only involved in transcription but is also an essential component of the eukaryotic nucleotide excision DNA repair (NER) pathway. XPD is a superfamily-2 5'-3' helicase containing an iron-sulphur cluster. Its helicase activity is indispensable for NER and it plays a role in the damage verification process. Here, we report the first structure of XPD from Thermoplasma acidophilum (taXPD) in complex with a short DNA fragment, thus revealing the polarity of the translocated strand and providing insights into how the enzyme achieves its 5'-3' directionality. Accompanied by a detailed mutational and biochemical analysis of taXPD, we define the path of the translocated DNA strand through the protein and identify amino acids that are critical for protein function.

-	~~{{STRUCTURE_4a15\| PDB=4a15 \| SCENE= }}~~	+	Functional and structural studies of the nucleotide excision repair helicase XPD suggest a polarity for DNA translocation.,Kuper J, Wolski SC, Michels G, Kisker C EMBO J. 2011 Nov 11;31(2):494-502. doi: 10.1038/emboj.2011.374. PMID:22081108<ref>PMID:22081108</ref>

-	~~===Crystal structure~~ of ~~an XPD DNA complex===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22081108}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[4a15]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4A15 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022081108<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: DNA helicase]]		[[Category: DNA helicase]]
	[[Category: Thermoplasma acidophilum]]		[[Category: Thermoplasma acidophilum]]

OCA at 10:25, 8 August 2012

2012-08-08T10:25:28Z

←Older revision		Revision as of 10:25, 8 August 2012
Line 1:		Line 1:
-	[[Image:4a15.~~jpg~~\|left\|200px]]	+	[[Image:4a15.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_4a15", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_4a15\| PDB=4a15 \| SCENE= }}		{{STRUCTURE_4a15\| PDB=4a15 \| SCENE= }}

	===Crystal structure of an XPD DNA complex===		===Crystal structure of an XPD DNA complex===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_22081108}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 22081108 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_22081108}}		{{ABSTRACT_PUBMED_22081108}}

OCA at 07:21, 1 February 2012

2012-02-01T07:21:49Z

←Older revision		Revision as of 07:21, 1 February 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4a15.jpg\|left\|200px]]

-	The ~~entry 4a15~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_4a15", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_4a15\| PDB=4a15 \| SCENE= }}

-	~~Authors: Kuper, J., Wolski, S., Michels, G., Kisker, C.~~	+	===Crystal structure of an XPD DNA complex===

-	~~Description~~: ~~Crystal~~ structure ~~of an XPD~~ DNA ~~complex~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22081108}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22081108 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22081108}}
		+
		+	==About this Structure==
		+	[[4a15]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A15 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022081108</ref><references group="xtra"/>
		+	[[Category: DNA helicase]]
		+	[[Category: Thermoplasma acidophilum]]
		+	[[Category: Kisker, C.]]
		+	[[Category: Kuper, J.]]
		+	[[Category: Michels, G.]]
		+	[[Category: Wolski, S C.]]
		+	[[Category: Helicase]]
		+	[[Category: Hydrolase]]
		+	[[Category: Nucleotide excision repair]]

OCA at 08:03, 2 November 2011

2011-11-02T08:03:57Z

←Older revision		Revision as of 08:03, 2 November 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4a15 is ON HOLD	+	The entry 4a15 is ON HOLD until Paper Publication

	Authors: Kuper, J., Wolski, S., Michels, G., Kisker, C.		Authors: Kuper, J., Wolski, S., Michels, G., Kisker, C.

	Description: Crystal structure of an XPD DNA complex		Description: Crystal structure of an XPD DNA complex

OCA: Protected "4a15" [edit=sysop:move=sysop]

2011-09-21T05:38:32Z

Protected "4a15" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:38, 21 September 2011

OCA: New page: '''Unreleased structure''' The entry 4a15 is ON HOLD Authors: Kuper, J., Wolski, S., Michels, G., Kisker, C. Description: Crystal structure of an XPD DNA complex

2011-09-21T05:38:30Z

New page: '''Unreleased structure''' The entry 4a15 is ON HOLD Authors: Kuper, J., Wolski, S., Michels, G., Kisker, C. Description: Crystal structure of an XPD DNA complex

New page

'''Unreleased structure'''

The entry 4a15 is ON HOLD

Authors: Kuper, J., Wolski, S., Michels, G., Kisker, C.

Description: Crystal structure of an XPD DNA complex