4aq1 - Revision history

OCA at 05:42, 25 August 2022

2022-08-25T05:42:23Z

←Older revision		Revision as of 05:42, 25 August 2022
Line 3:		Line 3:
	<StructureSection load='4aq1' size='340' side='right'caption='[[4aq1]], [[Resolution\|resolution]] 2.42Å' scene=''>		<StructureSection load='4aq1' size='340' side='right'caption='[[4aq1]], [[Resolution\|resolution]] 2.42Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4aq1]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980] and [~~http~~://en.wikipedia.org/wiki/Camelus_glama Camelus glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQ1 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4AQ1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4aq1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980] and [https://en.wikipedia.org/wiki/Camelus_glama Camelus glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AQ1 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4aq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4aq1 OCA], [~~http~~://pdbe.org/4aq1 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4aq1 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4aq1 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4aq1 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4aq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4aq1 OCA], [https://pdbe.org/4aq1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4aq1 RCSB], [https://www.ebi.ac.uk/pdbsum/4aq1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4aq1 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 19:		Line 19:
	==See Also==		==See Also==
	*[[Antibody 3D structures\|Antibody 3D structures]]		*[[Antibody 3D structures\|Antibody 3D structures]]
		+	*[[3D structures of non-human antibody\|3D structures of non-human antibody]]
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 26:
	[[Category: Atcc 12980]]		[[Category: Atcc 12980]]
	[[Category: Camelus glama]]		[[Category: Camelus glama]]
		+	[[Category: Large Structures]]
	[[Category: Baranova, E]]		[[Category: Baranova, E]]
	[[Category: Remaut, H]]		[[Category: Remaut, H]]

OCA at 09:27, 6 March 2019

2019-03-06T09:27:38Z

←Older revision		Revision as of 09:27, 6 March 2019
Line 1:		Line 1:

	==Structure of the SbsB S-layer protein of Geobacillus stearothermophilus PV72p2 in complex with nanobody KB6==		==Structure of the SbsB S-layer protein of Geobacillus stearothermophilus PV72p2 in complex with nanobody KB6==
-	<StructureSection load='4aq1' size='340' side='right' caption='[[4aq1]], [[Resolution\|resolution]] 2.42Å' scene=''>	+	<StructureSection load='4aq1' size='340' side='right'caption='[[4aq1]], [[Resolution\|resolution]] 2.42Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4aq1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980] and [http://en.wikipedia.org/wiki/Camelus_glama Camelus glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AQ1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4aq1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980] and [http://en.wikipedia.org/wiki/Camelus_glama Camelus glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AQ1 FirstGlance]. <br>
Line 16:		Line 16:
	</div>		</div>
	<div class="pdbe-citations 4aq1" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4aq1" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Antibody 3D structures\|Antibody 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:30, 11 August 2016

2016-08-11T16:30:39Z

←Older revision		Revision as of 16:30, 11 August 2016
Line 1:		Line 1:
		+
	==Structure of the SbsB S-layer protein of Geobacillus stearothermophilus PV72p2 in complex with nanobody KB6==		==Structure of the SbsB S-layer protein of Geobacillus stearothermophilus PV72p2 in complex with nanobody KB6==
	<StructureSection load='4aq1' size='340' side='right' caption='[[4aq1]], [[Resolution\|resolution]] 2.42Å' scene=''>		<StructureSection load='4aq1' size='340' side='right' caption='[[4aq1]], [[Resolution\|resolution]] 2.42Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4aq1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Geobacillus_stearothermophilus Geobacillus stearothermophilus~~] and [http://en.wikipedia.org/wiki/~~Lama_glama Lama~~ glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AQ1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4aq1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980] and [http://en.wikipedia.org/wiki/Camelus_glama Camelus glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AQ1 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4aq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4aq1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4aq1 RCSB], [http://www.ebi.ac.uk/pdbsum/4aq1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4aq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4aq1 OCA], [http://pdbe.org/4aq1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4aq1 RCSB], [http://www.ebi.ac.uk/pdbsum/4aq1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4aq1 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4aq1" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Geobacillus stearothermophilus~~]]	+	[[Category: Atcc 12980]]
-	[[Category: ~~Lama~~ glama]]	+	[[Category: Camelus glama]]
	[[Category: Baranova, E]]		[[Category: Baranova, E]]
	[[Category: Remaut, H]]		[[Category: Remaut, H]]

OCA at 13:08, 4 January 2015

2015-01-04T13:08:55Z

←Older revision		Revision as of 13:08, 4 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4aq1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus] and [http://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AQ1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4aq1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus] and [http://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AQ1 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4aq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4aq1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4aq1 RCSB], [http://www.ebi.ac.uk/pdbsum/4aq1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4aq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4aq1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4aq1 RCSB], [http://www.ebi.ac.uk/pdbsum/4aq1 PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 20:
	[[Category: Geobacillus stearothermophilus]]		[[Category: Geobacillus stearothermophilus]]
	[[Category: Lama glama]]		[[Category: Lama glama]]
-	[[Category: Baranova, E.]]	+	[[Category: Baranova, E]]
-	[[Category: Remaut, H.]]	+	[[Category: Remaut, H]]
	[[Category: Nanobody]]		[[Category: Nanobody]]
	[[Category: S-layer protein]]		[[Category: S-layer protein]]
	[[Category: Structural protein]]		[[Category: Structural protein]]

OCA at 08:13, 5 June 2014

2014-06-05T08:13:32Z

←Older revision		Revision as of 08:13, 5 June 2014
Line 1:		Line 1:
-	[[~~Image:~~4aq1.~~png~~\|~~left\|200px~~]]	+	==Structure of the SbsB S-layer protein of Geobacillus stearothermophilus PV72p2 in complex with nanobody KB6==
		+	<StructureSection load='4aq1' size='340' side='right' caption='[[4aq1]], [[Resolution\|resolution]] 2.42Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4aq1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus] and [http://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AQ1 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4aq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4aq1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4aq1 RCSB], [http://www.ebi.ac.uk/pdbsum/4aq1 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	S-layers are regular two-dimensional semipermeable protein layers that constitute a major cell-wall component in archaea and many bacteria. The nanoscale repeat structure of the S-layer lattices and their self-assembly from S-layer proteins (SLPs) have sparked interest in their use as patterning and display scaffolds for a range of nano-biotechnological applications. Despite their biological abundance and the technological interest in them, structural information about SLPs is limited to truncated and assembly-negative proteins. Here we report the X-ray structure of the SbsB SLP of Geobacillus stearothermophilus PV72/p2 by the use of nanobody-aided crystallization. SbsB consists of a seven-domain protein, formed by an amino-terminal cell-wall attachment domain and six consecutive immunoglobulin-like domains, that organize into a phi-shaped disk-like monomeric crystallization unit stabilized by interdomain Ca(2+) ion coordination. A Ca(2+)-dependent switch to the condensed SbsB quaternary structure pre-positions intermolecular contact zones and renders the protein competent for S-layer assembly. On the basis of crystal packing, chemical crosslinking data and cryo-electron microscopy projections, we present a model for the molecular organization of this SLP into a porous protein sheet inside the S-layer. The SbsB lattice represents a previously undescribed structural model for protein assemblies and may advance our understanding of SLP physiology and self-assembly, as well as the rational design of engineered higher-order structures for biotechnology.

-	~~{{STRUCTURE_4aq1\| PDB=4aq1 \| SCENE= }}~~	+	SbsB structure and lattice reconstruction unveil Ca2+ triggered S-layer assembly.,Baranova E, Fronzes R, Garcia-Pino A, Van Gerven N, Papapostolou D, Pehau-Arnaudet G, Pardon E, Steyaert J, Howorka S, Remaut H Nature. 2012 Jul 5;487(7405):119-22. PMID:22722836<ref>PMID:22722836</ref>

-	~~===Structure~~ of the ~~SbsB~~ S~~-layer protein~~ of ~~Geobacillus stearothermophilus PV72p2 in complex with nanobody KB6===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22722836}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[4aq1]] is a 4 chain structure with sequence from [http:~~//en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus] and [http://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQ1 OCA].	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022722836<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Geobacillus stearothermophilus]]		[[Category: Geobacillus stearothermophilus]]
	[[Category: Lama glama]]		[[Category: Lama glama]]

OCA at 07:26, 11 July 2012

2012-07-11T07:26:16Z

←Older revision		Revision as of 07:26, 11 July 2012
Line 1:		Line 1:
-	[[Image:4aq1.~~jpg~~\|left\|200px]]	+	[[Image:4aq1.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_4aq1", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_4aq1\| PDB=4aq1 \| SCENE= }}		{{STRUCTURE_4aq1\| PDB=4aq1 \| SCENE= }}

	===Structure of the SbsB S-layer protein of Geobacillus stearothermophilus PV72p2 in complex with nanobody KB6===		===Structure of the SbsB S-layer protein of Geobacillus stearothermophilus PV72p2 in complex with nanobody KB6===

		+	{{ABSTRACT_PUBMED_22722836}}

	==About this Structure==		==About this Structure==
	[[4aq1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus] and [http://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQ1 OCA].		[[4aq1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus] and [http://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQ1 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022722836</ref><references group="xtra"/>
	[[Category: Geobacillus stearothermophilus]]		[[Category: Geobacillus stearothermophilus]]
	[[Category: Lama glama]]		[[Category: Lama glama]]

OCA at 06:21, 13 June 2012

2012-06-13T06:21:06Z

←Older revision		Revision as of 06:21, 13 June 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4aq1.jpg\|left\|200px]]

-	The ~~entry 4aq1~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_4aq1", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_4aq1\| PDB=4aq1 \| SCENE= }}

-	~~Authors: Baranova, E., Remaut, H.~~	+	===Structure of the SbsB S-layer protein of Geobacillus stearothermophilus PV72p2 in complex with nanobody KB6===

-	~~Description:~~ Structure ~~of the SbsB~~ S-layer protein ~~of Geobacillus stearothermophilus PV72p2 in complex with nanobody KB6~~	+
		+	==About this Structure==
		+	[[4aq1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus] and [http://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQ1 OCA].
		+	[[Category: Geobacillus stearothermophilus]]
		+	[[Category: Lama glama]]
		+	[[Category: Baranova, E.]]
		+	[[Category: Remaut, H.]]
		+	[[Category: Nanobody]]
		+	[[Category: S-layer protein]]
		+	[[Category: Structural protein]]

OCA: Protected "4aq1" [edit=sysop:move=sysop]

2012-04-18T07:25:11Z

Protected "4aq1" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:25, 18 April 2012

OCA: New page: '''Unreleased structure''' The entry 4aq1 is ON HOLD Authors: Baranova, E., Remaut, H. Description: Structure of the SbsB S-layer protein of Geobacillus stearothermophilus PV72p2 in co...

2012-04-18T07:25:10Z

New page: '''Unreleased structure''' The entry 4aq1 is ON HOLD Authors: Baranova, E., Remaut, H. Description: Structure of the SbsB S-layer protein of Geobacillus stearothermophilus PV72p2 in co...

New page

'''Unreleased structure'''

The entry 4aq1 is ON HOLD

Authors: Baranova, E., Remaut, H.

Description: Structure of the SbsB S-layer protein of Geobacillus stearothermophilus PV72p2 in complex with nanobody KB6