4arg - Revision history

OCA at 10:53, 9 May 2024

2024-05-09T10:53:29Z

←Older revision		Revision as of 10:53, 9 May 2024
Line 3:		Line 3:
	<SX load='4arg' size='340' side='right' viewer='molstar' caption='[[4arg]], [[Resolution\|resolution]] 7.00Å' scene=''>		<SX load='4arg' size='340' side='right' viewer='molstar' caption='[[4arg]], [[Resolution\|resolution]] 7.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4arg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Mpmv Mpmv~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ARG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4arg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mason-Pfizer_monkey_virus Mason-Pfizer monkey virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ARG FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>[[~~4ard~~\|~~4ard~~]]~~</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 7Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4arg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4arg OCA], [https://pdbe.org/4arg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4arg RCSB], [https://www.ebi.ac.uk/pdbsum/4arg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4arg ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4arg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4arg OCA], [https://pdbe.org/4arg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4arg RCSB], [https://www.ebi.ac.uk/pdbsum/4arg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4arg ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/I6L8L3_MPMV I6L8L3_MPMV]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 26:
	</SX>		</SX>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Mpmv~~]]	+	[[Category: Mason-Pfizer monkey virus]]
-	[[Category: Bharat~~, T A.M~~]]	+	[[Category: Bharat TAM]]
-	[[Category: Briggs~~, J A.G~~]]	+	[[Category: Briggs JAG]]
-	[[Category: Davey~~, N E~~]]	+	[[Category: Davey NE]]
-	[[Category: Marco~~, A D~~]]	+	[[Category: Marco AD]]
-	[[Category: Riches~~, J D~~]]	+	[[Category: Riches JD]]
-	[[Category: Ruml, T]]	+	[[Category: Ruml T]]
-	[[Category: Rumlova, M]]	+	[[Category: Rumlova M]]
-	[[Category: Sachse, C]]	+	[[Category: Sachse C]]
-	[[Category: Ulbrich, P]]	+	[[Category: Ulbrich P]]
-	~~[[Category: Retrovirus]]~~	+
-	~~[[Category: Viral protein~~]]	+

OCA at 05:43, 25 August 2022

2022-08-25T05:43:48Z

←Older revision		Revision as of 05:43, 25 August 2022
Line 3:		Line 3:
	<SX load='4arg' size='340' side='right' viewer='molstar' caption='[[4arg]], [[Resolution\|resolution]] 7.00Å' scene=''>		<SX load='4arg' size='340' side='right' viewer='molstar' caption='[[4arg]], [[Resolution\|resolution]] 7.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4arg]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=4ARG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4arg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ARG FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ard\|4ard]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4ard\|4ard]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=4arg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4arg OCA], [~~http~~://pdbe.org/4arg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4arg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4arg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4arg ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4arg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4arg OCA], [https://pdbe.org/4arg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4arg RCSB], [https://www.ebi.ac.uk/pdbsum/4arg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4arg ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 16:
	</div>		</div>
	<div class="pdbe-citations 4arg" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4arg" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 18:52, 10 April 2020

2020-04-10T18:52:05Z

←Older revision		Revision as of 18:52, 10 April 2020
Line 3:		Line 3:
	<SX load='4arg' size='340' side='right' viewer='molstar' caption='[[4arg]], [[Resolution\|resolution]] 7.00Å' scene=''>		<SX load='4arg' size='340' side='right' viewer='molstar' caption='[[4arg]], [[Resolution\|resolution]] 7.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4arg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ARG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4arg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4ARG FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ard\|4ard]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ard\|4ard]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4arg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4arg OCA], [http://pdbe.org/4arg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4arg RCSB], [http://www.ebi.ac.uk/pdbsum/4arg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4arg ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4arg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4arg OCA], [http://pdbe.org/4arg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4arg RCSB], [http://www.ebi.ac.uk/pdbsum/4arg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4arg ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 17:48, 6 March 2020

2020-03-06T17:48:50Z

←Older revision		Revision as of 17:48, 6 March 2020
Line 1:		Line 1:

	==Structure of the immature retroviral capsid at 8A resolution by cryo- electron microscopy==		==Structure of the immature retroviral capsid at 8A resolution by cryo- electron microscopy==
-	<~~StructureSection~~ load='4arg' size='340' side='right'caption='[[4arg]], [[Resolution\|resolution]] 7.00Å' scene=''>	+	<SX load='4arg' size='340' side='right' viewer='molstar' caption='[[4arg]], [[Resolution\|resolution]] 7.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4arg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARG FirstGlance]. <br>		<table><tr><td colspan='2'>[[4arg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARG FirstGlance]. <br>
Line 19:		Line 19:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
		+	[[Category: Large Structures]]
	[[Category: Mpmv]]		[[Category: Mpmv]]
	[[Category: Bharat, T A.M]]		[[Category: Bharat, T A.M]]

OCA at 09:13, 6 March 2019

2019-03-06T09:13:37Z

←Older revision		Revision as of 09:13, 6 March 2019
Line 1:		Line 1:

	==Structure of the immature retroviral capsid at 8A resolution by cryo- electron microscopy==		==Structure of the immature retroviral capsid at 8A resolution by cryo- electron microscopy==
-	<StructureSection load='4arg' size='340' side='right' caption='[[4arg]], [[Resolution\|resolution]] 7.00Å' scene=''>	+	<StructureSection load='4arg' size='340' side='right'caption='[[4arg]], [[Resolution\|resolution]] 7.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4arg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARG FirstGlance]. <br>		<table><tr><td colspan='2'>[[4arg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARG FirstGlance]. <br>

OCA at 11:53, 11 August 2016

2016-08-11T11:53:48Z

←Older revision		Revision as of 11:53, 11 August 2016
Line 1:		Line 1:
		+
	==Structure of the immature retroviral capsid at 8A resolution by cryo- electron microscopy==		==Structure of the immature retroviral capsid at 8A resolution by cryo- electron microscopy==
	<StructureSection load='4arg' size='340' side='right' caption='[[4arg]], [[Resolution\|resolution]] 7.00Å' scene=''>		<StructureSection load='4arg' size='340' side='right' caption='[[4arg]], [[Resolution\|resolution]] 7.00Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4arg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARG FirstGlance]. <br>		<table><tr><td colspan='2'>[[4arg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARG FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ard\|4ard]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ard\|4ard]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4arg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4arg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4arg RCSB], [http://www.ebi.ac.uk/pdbsum/4arg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4arg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4arg OCA], [http://pdbe.org/4arg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4arg RCSB], [http://www.ebi.ac.uk/pdbsum/4arg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4arg ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4arg" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 14:04, 4 January 2015

2015-01-04T14:04:05Z

←Older revision		Revision as of 14:04, 4 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4arg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARG FirstGlance]. <br>		<table><tr><td colspan='2'>[[4arg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARG FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ard\|4ard]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ard\|4ard]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4arg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4arg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4arg RCSB], [http://www.ebi.ac.uk/pdbsum/4arg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4arg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4arg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4arg RCSB], [http://www.ebi.ac.uk/pdbsum/4arg PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 19:
	</StructureSection>		</StructureSection>
	[[Category: Mpmv]]		[[Category: Mpmv]]
-	[[Category: Bharat, T A.M.]]	+	[[Category: Bharat, T A.M]]
-	[[Category: Briggs, J A.G.]]	+	[[Category: Briggs, J A.G]]
-	[[Category: Davey, N E.]]	+	[[Category: Davey, N E]]
-	[[Category: Marco, A D.]]	+	[[Category: Marco, A D]]
-	[[Category: Riches, J D.]]	+	[[Category: Riches, J D]]
-	[[Category: Ruml, T.]]	+	[[Category: Ruml, T]]
-	[[Category: Rumlova, M.]]	+	[[Category: Rumlova, M]]
-	[[Category: Sachse, C.]]	+	[[Category: Sachse, C]]
-	[[Category: Ulbrich, P.]]	+	[[Category: Ulbrich, P]]
	[[Category: Retrovirus]]		[[Category: Retrovirus]]
	[[Category: Viral protein]]		[[Category: Viral protein]]

OCA at 07:49, 5 June 2014

2014-06-05T07:49:51Z

←Older revision		Revision as of 07:49, 5 June 2014
Line 1:		Line 1:
-	[[~~Image:~~4arg.~~png~~\|~~left~~\|~~200px~~]]	+	==Structure of the immature retroviral capsid at 8A resolution by cryo- electron microscopy==
		+	<StructureSection load='4arg' size='340' side='right' caption='[[4arg]], [[Resolution\|resolution]] 7.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4arg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mpmv Mpmv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARG FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ard\|4ard]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4arg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4arg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4arg RCSB], [http://www.ebi.ac.uk/pdbsum/4arg PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The assembly of retroviruses such as HIV-1 is driven by oligomerization of their major structural protein, Gag. Gag is a multidomain polyprotein including three conserved folded domains: MA (matrix), CA (capsid) and NC (nucleocapsid). Assembly of an infectious virion proceeds in two stages. In the first stage, Gag oligomerization into a hexameric protein lattice leads to the formation of an incomplete, roughly spherical protein shell that buds through the plasma membrane of the infected cell to release an enveloped immature virus particle. In the second stage, cleavage of Gag by the viral protease leads to rearrangement of the particle interior, converting the non-infectious immature virus particle into a mature infectious virion. The immature Gag shell acts as the pivotal intermediate in assembly and is a potential target for anti-retroviral drugs both in inhibiting virus assembly and in disrupting virus maturation. However, detailed structural information on the immature Gag shell has not previously been available. For this reason it is unclear what protein conformations and interfaces mediate the interactions between domains and therefore the assembly of retrovirus particles, and what structural transitions are associated with retrovirus maturation. Here we solve the structure of the immature retroviral Gag shell from Mason-Pfizer monkey virus by combining cryo-electron microscopy and tomography. The 8-A resolution structure permits the derivation of a pseudo-atomic model of CA in the immature retrovirus, which defines the protein interfaces mediating retrovirus assembly. We show that transition of an immature retrovirus into its mature infectious form involves marked rotations and translations of CA domains, that the roles of the amino-terminal and carboxy-terminal domains of CA in assembling the immature and mature hexameric lattices are exchanged, and that the CA interactions that stabilize the immature and mature viruses are almost completely distinct.

-	~~{{STRUCTURE_4arg\| PDB=4arg \| SCENE= }}~~	+	Structure of the immature retroviral capsid at 8 A resolution by cryo-electron microscopy.,Bharat TA, Davey NE, Ulbrich P, Riches JD, de Marco A, Rumlova M, Sachse C, Ruml T, Briggs JA Nature. 2012 Jul 19;487(7407):385-9. PMID:22722831<ref>PMID:22722831</ref>

-	~~===Structure~~ of the ~~immature retroviral capsid at 8A resolution by cryo- electron microscopy===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22722831}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[4arg]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Mason-pfizer_monkey_virus Mason-pfizer monkey virus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA].~~	+	</StructureSection>
-		+	[[Category: Mpmv]]
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022722831<~~/~~ref~~><~~references group="xtra"~~/>	+
-	[[Category: ~~Mason-pfizer monkey virus~~]]	+
	[[Category: Bharat, T A.M.]]		[[Category: Bharat, T A.M.]]
	[[Category: Briggs, J A.G.]]		[[Category: Briggs, J A.G.]]

OCA at 05:09, 1 August 2012

2012-08-01T05:09:05Z

←Older revision		Revision as of 05:09, 1 August 2012
Line 1:		Line 1:
-	[[Image:4arg.~~jpg~~\|left\|200px]]	+	[[Image:4arg.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_4arg", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_4arg\| PDB=4arg \| SCENE= }}		{{STRUCTURE_4arg\| PDB=4arg \| SCENE= }}

	===Structure of the immature retroviral capsid at 8A resolution by cryo- electron microscopy===		===Structure of the immature retroviral capsid at 8A resolution by cryo- electron microscopy===

		+	{{ABSTRACT_PUBMED_22722831}}

	==About this Structure==		==About this Structure==
	[[4arg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mason-pfizer_monkey_virus Mason-pfizer monkey virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA].		[[4arg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mason-pfizer_monkey_virus Mason-pfizer monkey virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022722831</ref><references group="xtra"/>
	[[Category: Mason-pfizer monkey virus]]		[[Category: Mason-pfizer monkey virus]]
	[[Category: Bharat, T A.M.]]		[[Category: Bharat, T A.M.]]

OCA at 06:03, 30 May 2012

2012-05-30T06:03:57Z

←Older revision		Revision as of 06:03, 30 May 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4arg.jpg\|left\|200px]]

-	The ~~entry 4arg~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_4arg", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_4arg\| PDB=4arg \| SCENE= }}

-	~~Authors: Bharat, T.A.M., Davey, N.E., Ulbrich, P., Riches, J.D., Marco, A.D., Rumlova, M., Sachse, C., Ruml, T., Briggs, J.A.G.~~	+	===Structure of the immature retroviral capsid at 8A resolution by cryo- electron microscopy===

-	~~Description:~~ Structure ~~of the immature retroviral capsid at 8A resolution by cryo~~-~~electron microscopy~~	+
		+	==About this Structure==
		+	[[4arg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mason-pfizer_monkey_virus Mason-pfizer monkey virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARG OCA].
		+	[[Category: Mason-pfizer monkey virus]]
		+	[[Category: Bharat, T A.M.]]
		+	[[Category: Briggs, J A.G.]]
		+	[[Category: Davey, N E.]]
		+	[[Category: Marco, A D.]]
		+	[[Category: Riches, J D.]]
		+	[[Category: Ruml, T.]]
		+	[[Category: Rumlova, M.]]
		+	[[Category: Sachse, C.]]
		+	[[Category: Ulbrich, P.]]
		+	[[Category: Retrovirus]]
		+	[[Category: Viral protein]]