4azi - Revision history

OCA at 11:39, 20 December 2023

2023-12-20T11:39:40Z

←Older revision		Revision as of 11:39, 20 December 2023
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	<StructureSection load='4azi' size='340' side='right'caption='[[4azi]], [[Resolution\|resolution]] 1.98Å' scene=''>		<StructureSection load='4azi' size='340' side='right'caption='[[4azi]], [[Resolution\|resolution]] 1.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4azi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Strpn Strpn~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AZI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AZI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4azi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AZI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AZI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCN:BICINE'>BCN</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OAN:O-(2-ACETAMIDO-2-DEOXY+D-GLUCOPYRANOSYLIDENE)+AMINO-N-PHENYLCARBAMATE'>OAN</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.98Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2yl5\|2yl5]], [[2yl6\|2yl6]], [[2yl8\|2yl8]], [[2yl9\|2yl9]], [[2yla\|2yla]], [[2yll\|2yll]], [[4az5\|4az5]], [[4az6\|4az6]], [[4az7\|4az7]], [[4azb\|4azb]], [[4azc\|4azc]], [[4azg\|4azg]], [[4azh\|4azh]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCN:BICINE'>BCN</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OAN:O-(2-ACETAMIDO-2-DEOXY+D-GLUCOPYRANOSYLIDENE)+AMINO-N-PHENYLCARBAMATE'>OAN</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4azi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4azi OCA], [https://pdbe.org/4azi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4azi RCSB], [https://www.ebi.ac.uk/pdbsum/4azi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4azi ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4azi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4azi OCA], [https://pdbe.org/4azi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4azi RCSB], [https://www.ebi.ac.uk/pdbsum/4azi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4azi ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/STRH_STRPN STRH_STRPN]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 27:		Line 28:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Beta-N-acetylhexosaminidase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Strpn~~]]	+	[[Category: Streptococcus pneumoniae TIGR4]]
-	[[Category: Boraston~~, A B~~]]	+	[[Category: Boraston AB]]
-	[[Category: Pluvinage, B]]	+	[[Category: Pluvinage B]]
-	[[Category: Stubbs~~, K A~~]]	+	[[Category: Stubbs KA]]
-	[[Category: Vocadlo~~, D J]]~~	+	[[Category: Vocadlo DJ]]
-	~~[[Category: Hydrolase~~]]	+

OCA at 05:52, 25 August 2022

2022-08-25T05:52:00Z

←Older revision		Revision as of 05:52, 25 August 2022
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	<StructureSection load='4azi' size='340' side='right'caption='[[4azi]], [[Resolution\|resolution]] 1.98Å' scene=''>		<StructureSection load='4azi' size='340' side='right'caption='[[4azi]], [[Resolution\|resolution]] 1.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4azi]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AZI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4AZI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4azi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AZI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AZI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCN:BICINE'>BCN</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OAN:O-(2-ACETAMIDO-2-DEOXY+D-GLUCOPYRANOSYLIDENE)+AMINO-N-PHENYLCARBAMATE'>OAN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCN:BICINE'>BCN</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OAN:O-(2-ACETAMIDO-2-DEOXY+D-GLUCOPYRANOSYLIDENE)+AMINO-N-PHENYLCARBAMATE'>OAN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yl5\|2yl5]], [[2yl6\|2yl6]], [[2yl8\|2yl8]], [[2yl9\|2yl9]], [[2yla\|2yla]], [[2yll\|2yll]], [[4az5\|4az5]], [[4az6\|4az6]], [[4az7\|4az7]], [[4azb\|4azb]], [[4azc\|4azc]], [[4azg\|4azg]], [[4azh\|4azh]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2yl5\|2yl5]], [[2yl6\|2yl6]], [[2yl8\|2yl8]], [[2yl9\|2yl9]], [[2yla\|2yla]], [[2yll\|2yll]], [[4az5\|4az5]], [[4az6\|4az6]], [[4az7\|4az7]], [[4azb\|4azb]], [[4azc\|4azc]], [[4azg\|4azg]], [[4azh\|4azh]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4azi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4azi OCA], [~~http~~://pdbe.org/4azi PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4azi RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4azi PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4azi ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4azi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4azi OCA], [https://pdbe.org/4azi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4azi RCSB], [https://www.ebi.ac.uk/pdbsum/4azi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4azi ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 21:		Line 21:
	==See Also==		==See Also==
	*[[Beta-Hexosaminidase\|Beta-Hexosaminidase]]		*[[Beta-Hexosaminidase\|Beta-Hexosaminidase]]
		+	*[[Beta-Hexosaminidase 3D structures\|Beta-Hexosaminidase 3D structures]]
		+	*[[Beta-N-acetylhexosaminidase 3D structures\|Beta-N-acetylhexosaminidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 26:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Beta-N-acetylhexosaminidase]]		[[Category: Beta-N-acetylhexosaminidase]]
		+	[[Category: Large Structures]]
	[[Category: Strpn]]		[[Category: Strpn]]
	[[Category: Boraston, A B]]		[[Category: Boraston, A B]]

OCA at 09:10, 6 March 2019

2019-03-06T09:10:42Z

←Older revision		Revision as of 09:10, 6 March 2019
Line 1:		Line 1:

	==Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH==		==Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH==
-	<StructureSection load='4azi' size='340' side='right' caption='[[4azi]], [[Resolution\|resolution]] 1.98Å' scene=''>	+	<StructureSection load='4azi' size='340' side='right'caption='[[4azi]], [[Resolution\|resolution]] 1.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4azi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AZI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AZI FirstGlance]. <br>		<table><tr><td colspan='2'>[[4azi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AZI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AZI FirstGlance]. <br>

OCA at 19:01, 11 August 2016

2016-08-11T19:01:26Z

←Older revision		Revision as of 19:01, 11 August 2016
Line 1:		Line 1:
		+
	==Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH==		==Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH==
	<StructureSection load='4azi' size='340' side='right' caption='[[4azi]], [[Resolution\|resolution]] 1.98Å' scene=''>		<StructureSection load='4azi' size='340' side='right' caption='[[4azi]], [[Resolution\|resolution]] 1.98Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yl5\|2yl5]], [[2yl6\|2yl6]], [[2yl8\|2yl8]], [[2yl9\|2yl9]], [[2yla\|2yla]], [[2yll\|2yll]], [[4az5\|4az5]], [[4az6\|4az6]], [[4az7\|4az7]], [[4azb\|4azb]], [[4azc\|4azc]], [[4azg\|4azg]], [[4azh\|4azh]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yl5\|2yl5]], [[2yl6\|2yl6]], [[2yl8\|2yl8]], [[2yl9\|2yl9]], [[2yla\|2yla]], [[2yll\|2yll]], [[4az5\|4az5]], [[4az6\|4az6]], [[4az7\|4az7]], [[4azb\|4azb]], [[4azc\|4azc]], [[4azg\|4azg]], [[4azh\|4azh]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4azi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4azi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4azi RCSB], [http://www.ebi.ac.uk/pdbsum/4azi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4azi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4azi OCA], [http://pdbe.org/4azi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4azi RCSB], [http://www.ebi.ac.uk/pdbsum/4azi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4azi ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4azi" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 13:59, 4 January 2015

2015-01-04T13:59:36Z

←Older revision		Revision as of 13:59, 4 January 2015
Line 1:		Line 1:
-	~~{{STRUCTURE_4azi\| PDB=4azi \| SCENE= }}~~	+	==Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH==
-	===Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH===	+	<StructureSection load='4azi' size='340' side='right' caption='[[4azi]], [[Resolution\|resolution]] 1.98Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24132305}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4azi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AZI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AZI FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCN:BICINE'>BCN</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OAN:O-(2-ACETAMIDO-2-DEOXY+D-GLUCOPYRANOSYLIDENE)+AMINO-N-PHENYLCARBAMATE'>OAN</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yl5\|2yl5]], [[2yl6\|2yl6]], [[2yl8\|2yl8]], [[2yl9\|2yl9]], [[2yla\|2yla]], [[2yll\|2yll]], [[4az5\|4az5]], [[4az6\|4az6]], [[4az7\|4az7]], [[4azb\|4azb]], [[4azc\|4azc]], [[4azg\|4azg]], [[4azh\|4azh]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4azi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4azi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4azi RCSB], [http://www.ebi.ac.uk/pdbsum/4azi PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Streptococcus pneumoniae produces a cell-surface attached beta-N-acetylglucosaminidase called StrH that is used by this pathogen to process the termini of host complex N-linked glycans. N-Acetyl-d-glucosamine-thiazoline (NAG-Thiazoline, NGT) and O-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino N-phenyl carbamate (PUGNAc) are inhibitors of the two family 20 glycoside hydrolase catalytic modules within StrH and these inhibitors have proven useful in modulating the activity of StrH in assays that model aspects of the host-bacterium interaction. Here we explore the molecular basis of StrH inhibition through structural, kinetic, thermodynamic and site-directed mutagenic analyses using the recombinantly produced independent catalytic modules of StrH (GH20A and GH20B) and the inhibitors NGT and PUGNAc. The results reveal a similar binding mode of the sugar moiety of these inhibitors at the -1 subsite in the active sites of GH20A and GH20B. The lower affinity of NGT as compared to PUGNAc for these catalytic modules can be attributed to the hydrophobic phenylcarbamate moiety of PUGNAc that is absent in NGT. This moiety also displayed variations in its interactions with the active sites of GH20A and GH20B that provide a rationale for the 400-fold difference observed in the Ki values of this compound for these two beta-N-acetylglucosaminidase catalytic modules.

-	~~==About this Structure==~~	+	Inhibition of the family 20 glycoside hydrolase catalytic modules in the Streptococcus pneumoniae exo-beta-d-N-acetylglucosaminidase, StrH.,Pluvinage B, Stubbs KA, Hattie M, Vocadlo DJ, Boraston AB Org Biomol Chem. 2013 Oct 16. PMID:24132305<ref>PMID:24132305</ref>
-	~~[[4azi]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Strpn Strpn]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=4AZI OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Beta-Hexosaminidase\|Beta-Hexosaminidase]]		*[[Beta-Hexosaminidase\|Beta-Hexosaminidase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:024132305</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Beta-N-acetylhexosaminidase]]		[[Category: Beta-N-acetylhexosaminidase]]
	[[Category: Strpn]]		[[Category: Strpn]]
-	[[Category: Boraston, A B.]]	+	[[Category: Boraston, A B]]
-	[[Category: Pluvinage, B.]]	+	[[Category: Pluvinage, B]]
-	[[Category: Stubbs, K A.]]	+	[[Category: Stubbs, K A]]
-	[[Category: Vocadlo, D J.]]	+	[[Category: Vocadlo, D J]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 06:48, 13 November 2013

2013-11-13T06:48:35Z

←Older revision		Revision as of 06:48, 13 November 2013
Line 4:		Line 4:

	==About this Structure==		==About this Structure==
-	[[4azi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AZI OCA].	+	[[4azi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AZI OCA].

	==See Also==		==See Also==
Line 12:		Line 12:
	<ref group="xtra">PMID:024132305</ref><references group="xtra"/><references/>		<ref group="xtra">PMID:024132305</ref><references group="xtra"/><references/>
	[[Category: Beta-N-acetylhexosaminidase]]		[[Category: Beta-N-acetylhexosaminidase]]
-	[[Category: ~~Streptococcus pneumoniae tigr4~~]]	+	[[Category: Strpn]]
	[[Category: Boraston, A B.]]		[[Category: Boraston, A B.]]
	[[Category: Pluvinage, B.]]		[[Category: Pluvinage, B.]]

OCA at 08:43, 30 October 2013

2013-10-30T08:43:06Z

←Older revision		Revision as of 08:43, 30 October 2013
Line 1:		Line 1:
	{{STRUCTURE_4azi\| PDB=4azi \| SCENE= }}		{{STRUCTURE_4azi\| PDB=4azi \| SCENE= }}
	===Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH===		===Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH===
		+	{{ABSTRACT_PUBMED_24132305}}

	==About this Structure==		==About this Structure==
	[[4azi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AZI OCA].		[[4azi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AZI OCA].
		+
		+	==See Also==
		+	*[[Beta-Hexosaminidase\|Beta-Hexosaminidase]]
		+
		+	==Reference==
		+	<ref group="xtra">PMID:024132305</ref><references group="xtra"/><references/>
	[[Category: Beta-N-acetylhexosaminidase]]		[[Category: Beta-N-acetylhexosaminidase]]
	[[Category: Streptococcus pneumoniae tigr4]]		[[Category: Streptococcus pneumoniae tigr4]]

OCA at 15:50, 10 July 2013

2013-07-10T15:50:17Z

←Older revision		Revision as of 15:50, 10 July 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4azi\| PDB=4azi \| SCENE= }}
		+	===Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH===

-	~~The entry~~ 4azi is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
-		+	[[4azi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AZI OCA].
-	~~Authors~~: ~~Pluvinage~~, B., Stubbs, K.A., Vocadlo, D.J.~~, Boraston, A.B.~~	+	[[Category: Beta-N-acetylhexosaminidase]]
-		+	[[Category: Streptococcus pneumoniae tigr4]]
-	~~Description~~: ~~Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH~~	+	[[Category: Boraston, A B.]]
		+	[[Category: Pluvinage, B.]]
		+	[[Category: Stubbs, K A.]]
		+	[[Category: Vocadlo, D J.]]
		+	[[Category: Hydrolase]]

OCA at 19:40, 17 April 2013

2013-04-17T19:40:41Z

←Older revision		Revision as of 19:40, 17 April 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4azi is ON HOLD	+	The entry 4azi is ON HOLD until Paper Publication

	Authors: Pluvinage, B., Stubbs, K.A., Vocadlo, D.J., Boraston, A.B.		Authors: Pluvinage, B., Stubbs, K.A., Vocadlo, D.J., Boraston, A.B.

	Description: Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH		Description: Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH

OCA: Protected "4azi" [edit=sysop:move=sysop]

2012-07-04T07:08:55Z

Protected "4azi" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:08, 4 July 2012