4bd6 - Revision history

OCA at 07:17, 1 May 2024

2024-05-01T07:17:41Z

←Older revision		Revision as of 07:17, 1 May 2024
Line 3:		Line 3:
	<StructureSection load='4bd6' size='340' side='right'caption='[[4bd6]], [[Resolution\|resolution]] 2.49Å' scene=''>		<StructureSection load='4bd6' size='340' side='right'caption='[[4bd6]], [[Resolution\|resolution]] 2.49Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4bd6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BD6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BD6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4bd6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BD6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BD6 FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[4bd2\|4bd2]]~~, [[~~4bd7~~\|~~4bd7~~]]~~, [[4bd8\|4bd8]], [[4bdu\|4bdu]]</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.494Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bd6 OCA], [https://pdbe.org/4bd6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bd6 RCSB], [https://www.ebi.ac.uk/pdbsum/4bd6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bd6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bd6 OCA], [https://pdbe.org/4bd6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bd6 RCSB], [https://www.ebi.ac.uk/pdbsum/4bd6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bd6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/BAX_HUMAN BAX_HUMAN]] Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.<ref>PMID:8358790</ref> <ref>PMID:10772918</ref> <ref>PMID:8521816</ref> <ref>PMID:16113678</ref> <ref>PMID:18948948</ref> <ref>PMID:21199865</ref>	+	[https://www.uniprot.org/uniprot/BAX_HUMAN BAX_HUMAN] Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.<ref>PMID:8358790</ref> <ref>PMID:10772918</ref> <ref>PMID:8521816</ref> <ref>PMID:16113678</ref> <ref>PMID:18948948</ref> <ref>PMID:21199865</ref>
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	In stressed cells, apoptosis ensues when Bcl-2 family members Bax or Bak oligomerize and permeabilize the mitochondrial outer membrane. Certain BH3-only relatives can directly activate them to mediate this pivotal, poorly understood step. To clarify the conformational changes that induce Bax oligomerization, we determined crystal structures of BaxDeltaC21 treated with detergents and BH3 peptides. The peptides bound the Bax canonical surface groove but, unlike their complexes with prosurvival relatives, dissociated Bax into two domains. The structures define the sequence signature of activator BH3 domains and reveal how they can activate Bax via its groove by favoring release of its BH3 domain. Furthermore, Bax helices alpha2-alpha5 alone adopted a symmetric homodimer structure, supporting the proposal that two Bax molecules insert their BH3 domain into each other's surface groove to nucleate oligomerization. A planar lipophilic surface on this homodimer may engage the membrane. Our results thus define critical Bax transitions toward apoptosis.	+
-		+
-	Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis.,Czabotar PE, Westphal D, Dewson G, Ma S, Hockings C, Fairlie WD, Lee EF, Yao S, Robin AY, Smith BJ, Huang DC, Kluck RM, Adams JM, Colman PM Cell. 2013 Jan 31;152(3):519-31. doi: 10.1016/j.cell.2012.12.031. PMID:23374347<ref>PMID:23374347</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 4bd6" style="background-color:#fffaf0;"></div~~>	+

	==See Also==		==See Also==
Line 25:		Line 16:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Adams~~, J M~~]]	+	[[Category: Adams JM]]
-	[[Category: Colman~~, P M~~]]	+	[[Category: Colman PM]]
-	[[Category: Czabotar~~, P E~~]]	+	[[Category: Czabotar PE]]
-	[[Category: Westphal, D]]	+	[[Category: Westphal D]]
-	~~[[Category: Apoptosis]]~~	+
-	~~[[Category: Programmed cell death~~]]	+

OCA at 07:08, 31 August 2022

2022-08-31T07:08:55Z

←Older revision		Revision as of 07:08, 31 August 2022
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	<StructureSection load='4bd6' size='340' side='right'caption='[[4bd6]], [[Resolution\|resolution]] 2.49Å' scene=''>		<StructureSection load='4bd6' size='340' side='right'caption='[[4bd6]], [[Resolution\|resolution]] 2.49Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4bd6]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BD6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4BD6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4bd6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BD6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BD6 FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bd2\|4bd2]], [[4bd7\|4bd7]], [[4bd8\|4bd8]], [[4bdu\|4bdu]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4bd2\|4bd2]], [[4bd7\|4bd7]], [[4bd8\|4bd8]], [[4bdu\|4bdu]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4bd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bd6 OCA], [~~http~~://pdbe.org/4bd6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4bd6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4bd6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4bd6 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bd6 OCA], [https://pdbe.org/4bd6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bd6 RCSB], [https://www.ebi.ac.uk/pdbsum/4bd6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bd6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/BAX_HUMAN BAX_HUMAN]] Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.<ref>PMID:8358790</ref> <ref>PMID:10772918</ref> <ref>PMID:8521816</ref> <ref>PMID:16113678</ref> <ref>PMID:18948948</ref> <ref>PMID:21199865</ref>	+	[[https://www.uniprot.org/uniprot/BAX_HUMAN BAX_HUMAN]] Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.<ref>PMID:8358790</ref> <ref>PMID:10772918</ref> <ref>PMID:8521816</ref> <ref>PMID:16113678</ref> <ref>PMID:18948948</ref> <ref>PMID:21199865</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[B-cell lymphoma ~~protein~~\|B-cell lymphoma ~~protein~~]]	+	*[[B-cell lymphoma proteins 3D structures\|B-cell lymphoma proteins 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:15, 13 March 2019

2019-03-13T13:15:43Z

←Older revision		Revision as of 13:15, 13 March 2019
Line 1:		Line 1:

	==Bax domain swapped dimer in complex with BaxBH3==		==Bax domain swapped dimer in complex with BaxBH3==
-	<StructureSection load='4bd6' size='340' side='right' caption='[[4bd6]], [[Resolution\|resolution]] 2.49Å' scene=''>	+	<StructureSection load='4bd6' size='340' side='right'caption='[[4bd6]], [[Resolution\|resolution]] 2.49Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4bd6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BD6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BD6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4bd6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BD6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BD6 FirstGlance]. <br>
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4bd6" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4bd6" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[B-cell lymphoma protein\|B-cell lymphoma protein]]
	== References ==		== References ==
	<references/>		<references/>
Line 23:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Adams, J M]]		[[Category: Adams, J M]]
	[[Category: Colman, P M]]		[[Category: Colman, P M]]

OCA at 17:12, 4 August 2016

2016-08-04T17:12:59Z

←Older revision		Revision as of 17:12, 4 August 2016
Line 1:		Line 1:
		+
	==Bax domain swapped dimer in complex with BaxBH3==		==Bax domain swapped dimer in complex with BaxBH3==
	<StructureSection load='4bd6' size='340' side='right' caption='[[4bd6]], [[Resolution\|resolution]] 2.49Å' scene=''>		<StructureSection load='4bd6' size='340' side='right' caption='[[4bd6]], [[Resolution\|resolution]] 2.49Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4bd6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BD6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BD6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4bd6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BD6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BD6 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bd2\|4bd2]], [[4bd7\|4bd7]], [[4bd8\|4bd8]], [[4bdu\|4bdu]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bd2\|4bd2]], [[4bd7\|4bd7]], [[4bd8\|4bd8]], [[4bdu\|4bdu]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bd6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bd6 RCSB], [http://www.ebi.ac.uk/pdbsum/4bd6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bd6 OCA], [http://pdbe.org/4bd6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bd6 RCSB], [http://www.ebi.ac.uk/pdbsum/4bd6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bd6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4bd6" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Adams, J M]]		[[Category: Adams, J M]]
	[[Category: Colman, P M]]		[[Category: Colman, P M]]

OCA at 11:18, 25 December 2014

2014-12-25T11:18:03Z

←Older revision		Revision as of 11:18, 25 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bd6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bd6 RCSB], [http://www.ebi.ac.uk/pdbsum/4bd6 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bd6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bd6 RCSB], [http://www.ebi.ac.uk/pdbsum/4bd6 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/BAX_HUMAN BAX_HUMAN]] Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.<ref>PMID:8358790</ref> <ref>PMID:10772918</ref> <ref>PMID:8521816</ref> <ref>PMID:16113678</ref> <ref>PMID:18948948</ref> <ref>PMID:21199865</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 15:05, 9 December 2014

2014-12-09T15:05:08Z

←Older revision		Revision as of 15:05, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~4bd6.~~jpg~~\|~~left~~\|~~200px~~]]	+	==Bax domain swapped dimer in complex with BaxBH3==
		+	<StructureSection load='4bd6' size='340' side='right' caption='[[4bd6]], [[Resolution\|resolution]] 2.49Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4bd6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BD6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BD6 FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bd2\|4bd2]], [[4bd7\|4bd7]], [[4bd8\|4bd8]], [[4bdu\|4bdu]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bd6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bd6 RCSB], [http://www.ebi.ac.uk/pdbsum/4bd6 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In stressed cells, apoptosis ensues when Bcl-2 family members Bax or Bak oligomerize and permeabilize the mitochondrial outer membrane. Certain BH3-only relatives can directly activate them to mediate this pivotal, poorly understood step. To clarify the conformational changes that induce Bax oligomerization, we determined crystal structures of BaxDeltaC21 treated with detergents and BH3 peptides. The peptides bound the Bax canonical surface groove but, unlike their complexes with prosurvival relatives, dissociated Bax into two domains. The structures define the sequence signature of activator BH3 domains and reveal how they can activate Bax via its groove by favoring release of its BH3 domain. Furthermore, Bax helices alpha2-alpha5 alone adopted a symmetric homodimer structure, supporting the proposal that two Bax molecules insert their BH3 domain into each other's surface groove to nucleate oligomerization. A planar lipophilic surface on this homodimer may engage the membrane. Our results thus define critical Bax transitions toward apoptosis.

-	~~{{STRUCTURE_4bd6\| PDB=4bd6 \| SCENE= }}~~	+	Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis.,Czabotar PE, Westphal D, Dewson G, Ma S, Hockings C, Fairlie WD, Lee EF, Yao S, Robin AY, Smith BJ, Huang DC, Kluck RM, Adams JM, Colman PM Cell. 2013 Jan 31;152(3):519-31. doi: 10.1016/j.cell.2012.12.031. PMID:23374347<ref>PMID:23374347</ref>

-	~~===Bax domain swapped dimer in complex with BaxBH3===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_23374347}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[4bd6]] is a 2 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BD6 OCA].~~	+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Adams, J M.]]	+	[[Category: Adams, J M]]
-	[[Category: Colman, P M.]]	+	[[Category: Colman, P M]]
-	[[Category: Czabotar, P E.]]	+	[[Category: Czabotar, P E]]
-	[[Category: Westphal, D.]]	+	[[Category: Westphal, D]]
	[[Category: Apoptosis]]		[[Category: Apoptosis]]
	[[Category: Programmed cell death]]		[[Category: Programmed cell death]]

OCA at 10:28, 13 February 2013

2013-02-13T10:28:40Z

←Older revision		Revision as of 10:28, 13 February 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4bd6.jpg\|left\|200px]]

-	~~The entry~~ 4bd6 ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_4bd6\| PDB=4bd6 \| SCENE= }}

-	~~Authors: Czabotar, P.E., Westphal, D., Adams, J.M., Colman, P.M.~~	+	===Bax domain swapped dimer in complex with BaxBH3===

-	~~Description~~:	+	{{ABSTRACT_PUBMED_23374347}}
		+
		+	==About this Structure==
		+	[[4bd6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BD6 OCA].
		+	[[Category: Homo sapiens]]
		+	[[Category: Adams, J M.]]
		+	[[Category: Colman, P M.]]
		+	[[Category: Czabotar, P E.]]
		+	[[Category: Westphal, D.]]
		+	[[Category: Apoptosis]]
		+	[[Category: Programmed cell death]]

OCA at 13:12, 8 November 2012

2012-11-08T13:12:40Z

←Older revision		Revision as of 13:12, 8 November 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4bd6 is ON HOLD	+	The entry 4bd6 is ON HOLD until Paper Publication

	Authors: Czabotar, P.E., Westphal, D., Adams, J.M., Colman, P.M.		Authors: Czabotar, P.E., Westphal, D., Adams, J.M., Colman, P.M.

-	Description: ~~TBA2~~	+	Description:

OCA: Protected "4bd6" [edit=sysop:move=sysop]

2012-10-10T06:44:58Z

Protected "4bd6" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:44, 10 October 2012

OCA: New page: '''Unreleased structure''' The entry 4bd6 is ON HOLD Authors: Czabotar, P.E., Westphal, D., Adams, J.M., Colman, P.M. Description: TBA2

2012-10-10T06:44:57Z

New page: '''Unreleased structure''' The entry 4bd6 is ON HOLD Authors: Czabotar, P.E., Westphal, D., Adams, J.M., Colman, P.M. Description: TBA2

New page

'''Unreleased structure'''

The entry 4bd6 is ON HOLD

Authors: Czabotar, P.E., Westphal, D., Adams, J.M., Colman, P.M.

Description: TBA2