4bx4 - Revision history

OCA at 11:06, 9 May 2024

2024-05-09T11:06:35Z

←Older revision		Revision as of 11:06, 9 May 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4bx4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_phage_phi8 Pseudomonas phage phi8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BX4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BX4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4bx4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_phage_phi8 Pseudomonas phage phi8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BX4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BX4 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bx4 OCA], [https://pdbe.org/4bx4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bx4 RCSB], [https://www.ebi.ac.uk/pdbsum/4bx4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bx4 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 8.7Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bx4 OCA], [https://pdbe.org/4bx4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bx4 RCSB], [https://www.ebi.ac.uk/pdbsum/4bx4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bx4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/Q9MC13_9VIRU Q9MC13_9VIRU]]	+	[https://www.uniprot.org/uniprot/Q9MC13_9VIRU Q9MC13_9VIRU]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The hallmark of a virus is its capsid, which harbors the viral genome and is formed from protein subunits, which assemble following precise geometric rules. dsRNA viruses use an unusual protein multiplicity (120 copies) to form their closed capsids. We have determined the atomic structure of the capsid protein (P1) from the dsRNA cystovirus Phi8. In the crystal P1 forms pentamers, very similar in shape to facets of empty procapsids, suggesting an unexpected assembly pathway that proceeds via a pentameric intermediate. Unlike the elongated proteins used by dsRNA mammalian reoviruses, P1 has a compact trapezoid-like shape and a distinct arrangement in the shell, with two near-identical conformers in nonequivalent structural environments. Nevertheless, structural similarity with the analogous protein from the mammalian viruses suggests a common ancestor. The unusual shape of the molecule may facilitate dramatic capsid expansion during phage maturation, allowing P1 to switch interaction interfaces to provide capsid plasticity.
		+
		+	Plate Tectonics of Virus Shell Assembly and Reorganization in Phage Phi8, a Distant Relative of Mammalian Reoviruses.,El Omari K, Sutton G, Ravantti JJ, Zhang H, Walter TS, Grimes JM, Bamford DH, Stuart DI, Mancini EJ Structure. 2013 Jul 23. pii: S0969-2126(13)00240-2. doi:, 10.1016/j.str.2013.06.017. PMID:23891291<ref>PMID:23891291</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 4bx4" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</SX>		</SX>

OCA at 17:14, 7 September 2022

2022-09-07T17:14:32Z

←Older revision		Revision as of 17:14, 7 September 2022
Line 3:		Line 3:
	<SX load='4bx4' size='340' side='right' viewer='molstar' caption='[[4bx4]], [[Resolution\|resolution]] 8.70Å' scene=''>		<SX load='4bx4' size='340' side='right' viewer='molstar' caption='[[4bx4]], [[Resolution\|resolution]] 8.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4bx4]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Bacteriophage_phi-8 Bacteriophage phi-8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BX4 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=4BX4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4bx4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_phage_phi8 Pseudomonas phage phi8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BX4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BX4 FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bwy\|4bwy]]</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bx4 OCA], [https://pdbe.org/4bx4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bx4 RCSB], [https://www.ebi.ac.uk/pdbsum/4bx4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bx4 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=4bx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bx4 OCA], [~~http~~://pdbe.org/4bx4 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4bx4 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4bx4 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4bx4 ProSAT]</span></td></tr>	+
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[[https://www.uniprot.org/uniprot/Q9MC13_9VIRU Q9MC13_9VIRU]]
-	The hallmark of a virus is its capsid, which harbors the viral genome and is formed from protein subunits, which assemble following precise geometric rules. dsRNA viruses use an unusual protein multiplicity (120 copies) to form their closed capsids. We have determined the atomic structure of the capsid protein (P1) from the dsRNA cystovirus Phi8. In the crystal P1 forms pentamers, very similar in shape to facets of empty procapsids, suggesting an unexpected assembly pathway that proceeds via a pentameric intermediate. Unlike the elongated proteins used by dsRNA mammalian reoviruses, P1 has a compact trapezoid-like shape and a distinct arrangement in the shell, with two near-identical conformers in nonequivalent structural environments. Nevertheless, structural similarity with the analogous protein from the mammalian viruses suggests a common ancestor. The unusual shape of the molecule may facilitate dramatic capsid expansion during phage maturation, allowing P1 to switch interaction interfaces to provide capsid plasticity.	+
-		+
-	Plate Tectonics of Virus Shell Assembly and Reorganization in Phage Phi8, a Distant Relative of Mammalian Reoviruses.,El Omari K, Sutton G, Ravantti JJ, Zhang H, Walter TS, Grimes JM, Bamford DH, Stuart DI, Mancini EJ Structure. 2013 Jul 23. pii: ~~S0969-2126(13)00240-2. doi:, 10.1016~~/~~j.str.2013.06.017. PMID:23891291<ref>PMID:23891291<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 4bx4" style="background-color:#fffaf0;"></div>~~	+
-	~~== References ==~~	+
-	~~<references~~/>	+
	__TOC__		__TOC__
	</SX>		</SX>
-	[[Category: Bacteriophage phi-8]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Bamford, D H~~]]	+	[[Category: Pseudomonas phage phi8]]
-	[[Category: ~~Grimes, J M]]~~	+	[[Category: Bamford DH]]
-	~~[[Category: Mancini, E J~~]]	+	[[Category: El Omari K]]
-	[[Category: Omari, K El]]	+	[[Category: Grimes JM]]
-	[[Category: ~~Ravantti, J J~~]]	+	[[Category: Mancini EJ]]
-	[[Category: ~~Stuart, D I~~]]	+	[[Category: Ravantti JJ]]
-	[[Category: ~~Sutton, G~~]]	+	[[Category: Stuart DI]]
-	[[Category: ~~Walter, T S~~]]	+	[[Category: Sutton G]]
-	[[Category: ~~Zhang, H~~]]	+	[[Category: Walter TS]]
-	[[Category: ~~Bacteriophage~~]]	+	[[Category: Zhang H]]
-	[[Category: ~~Virus~~]]	+

OCA at 18:57, 10 April 2020

2020-04-10T18:57:56Z

←Older revision		Revision as of 18:57, 10 April 2020
Line 3:		Line 3:
	<SX load='4bx4' size='340' side='right' viewer='molstar' caption='[[4bx4]], [[Resolution\|resolution]] 8.70Å' scene=''>		<SX load='4bx4' size='340' side='right' viewer='molstar' caption='[[4bx4]], [[Resolution\|resolution]] 8.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4bx4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_phi-8 Bacteriophage phi-8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BX4 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4BX4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4bx4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_phi-8 Bacteriophage phi-8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BX4 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4BX4 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bwy\|4bwy]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bwy\|4bwy]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4bx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bx4 OCA], [http://pdbe.org/4bx4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bx4 RCSB], [http://www.ebi.ac.uk/pdbsum/4bx4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bx4 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4bx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bx4 OCA], [http://pdbe.org/4bx4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bx4 RCSB], [http://www.ebi.ac.uk/pdbsum/4bx4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bx4 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 17:51, 6 March 2020

2020-03-06T17:51:31Z

←Older revision		Revision as of 17:51, 6 March 2020
Line 1:		Line 1:

	==Fitting of the bacteriophage Phi8 P1 capsid protein into cryo-EM density==		==Fitting of the bacteriophage Phi8 P1 capsid protein into cryo-EM density==
-	<~~StructureSection~~ load='4bx4' size='340' side='right'caption='[[4bx4]], [[Resolution\|resolution]] 8.70Å' scene=''>	+	<SX load='4bx4' size='340' side='right' viewer='molstar' caption='[[4bx4]], [[Resolution\|resolution]] 8.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4bx4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_phi-8 Bacteriophage phi-8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BX4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4bx4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_phi-8 Bacteriophage phi-8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BX4 FirstGlance]. <br>
Line 19:		Line 19:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Bacteriophage phi-8]]		[[Category: Bacteriophage phi-8]]
	[[Category: Large Structures]]		[[Category: Large Structures]]

OCA at 16:32, 28 August 2019

2019-08-28T16:32:14Z

←Older revision		Revision as of 16:32, 28 August 2019
Line 1:		Line 1:

	==Fitting of the bacteriophage Phi8 P1 capsid protein into cryo-EM density==		==Fitting of the bacteriophage Phi8 P1 capsid protein into cryo-EM density==
-	<StructureSection load='4bx4' size='340' side='right' caption='[[4bx4]], [[Resolution\|resolution]] 8.70Å' scene=''>	+	<StructureSection load='4bx4' size='340' side='right'caption='[[4bx4]], [[Resolution\|resolution]] 8.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4bx4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_phi-8 Bacteriophage phi-8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BX4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4bx4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_phi-8 Bacteriophage phi-8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BX4 FirstGlance]. <br>
Line 21:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Bacteriophage phi-8]]		[[Category: Bacteriophage phi-8]]
		+	[[Category: Large Structures]]
	[[Category: Bamford, D H]]		[[Category: Bamford, D H]]
	[[Category: Grimes, J M]]		[[Category: Grimes, J M]]

OCA at 22:18, 15 November 2017

2017-11-15T22:18:29Z

←Older revision		Revision as of 22:18, 15 November 2017
Line 5:		Line 5:
	<table><tr><td colspan='2'>[[4bx4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_phi-8 Bacteriophage phi-8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BX4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4bx4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_phi-8 Bacteriophage phi-8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BX4 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bwy\|4bwy]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bwy\|4bwy]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bx4 OCA], [http://pdbe.org/4bx4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bx4 RCSB], [http://www.ebi.ac.uk/pdbsum/4bx4 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bx4 OCA], [http://pdbe.org/4bx4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bx4 RCSB], [http://www.ebi.ac.uk/pdbsum/4bx4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bx4 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 05:44, 11 May 2016

2016-05-11T05:44:59Z

←Older revision		Revision as of 05:44, 11 May 2016
Line 1:		Line 1:
		+
	==Fitting of the bacteriophage Phi8 P1 capsid protein into cryo-EM density==		==Fitting of the bacteriophage Phi8 P1 capsid protein into cryo-EM density==
	<StructureSection load='4bx4' size='340' side='right' caption='[[4bx4]], [[Resolution\|resolution]] 8.70Å' scene=''>		<StructureSection load='4bx4' size='340' side='right' caption='[[4bx4]], [[Resolution\|resolution]] 8.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4bx4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pseudomonas_phage_phi8 Pseudomonas phage phi8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BX4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4bx4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_phi-8 Bacteriophage phi-8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BX4 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bwy\|4bwy]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bwy\|4bwy]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bx4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bx4 RCSB], [http://www.ebi.ac.uk/pdbsum/4bx4 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bx4 OCA], [http://pdbe.org/4bx4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bx4 RCSB], [http://www.ebi.ac.uk/pdbsum/4bx4 PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4bx4" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Pseudomonas phage phi8~~]]	+	[[Category: Bacteriophage phi-8]]
	[[Category: Bamford, D H]]		[[Category: Bamford, D H]]
	[[Category: Grimes, J M]]		[[Category: Grimes, J M]]

OCA at 09:23, 21 December 2014

2014-12-21T09:23:16Z

←Older revision		Revision as of 09:23, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4bx4\| PDB=4bx4 \| SCENE= }}~~	+	==Fitting of the bacteriophage Phi8 P1 capsid protein into cryo-EM density==
-	===Fitting of the bacteriophage Phi8 P1 capsid protein into cryo-EM density===	+	<StructureSection load='4bx4' size='340' side='right' caption='[[4bx4]], [[Resolution\|resolution]] 8.70Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23891291}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4bx4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_phage_phi8 Pseudomonas phage phi8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BX4 FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bwy\|4bwy]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bx4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bx4 RCSB], [http://www.ebi.ac.uk/pdbsum/4bx4 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The hallmark of a virus is its capsid, which harbors the viral genome and is formed from protein subunits, which assemble following precise geometric rules. dsRNA viruses use an unusual protein multiplicity (120 copies) to form their closed capsids. We have determined the atomic structure of the capsid protein (P1) from the dsRNA cystovirus Phi8. In the crystal P1 forms pentamers, very similar in shape to facets of empty procapsids, suggesting an unexpected assembly pathway that proceeds via a pentameric intermediate. Unlike the elongated proteins used by dsRNA mammalian reoviruses, P1 has a compact trapezoid-like shape and a distinct arrangement in the shell, with two near-identical conformers in nonequivalent structural environments. Nevertheless, structural similarity with the analogous protein from the mammalian viruses suggests a common ancestor. The unusual shape of the molecule may facilitate dramatic capsid expansion during phage maturation, allowing P1 to switch interaction interfaces to provide capsid plasticity.

-	~~==About this Structure==~~	+	Plate Tectonics of Virus Shell Assembly and Reorganization in Phage Phi8, a Distant Relative of Mammalian Reoviruses.,El Omari K, Sutton G, Ravantti JJ, Zhang H, Walter TS, Grimes JM, Bamford DH, Stuart DI, Mancini EJ Structure. 2013 Jul 23. pii: S0969-2126(13)00240-2. doi:, 10.1016/j.str.2013.06.017. PMID:23891291<ref>PMID:23891291</ref>
-	~~[[4bx4]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Pseudomonas_phage_phi8 Pseudomonas phage phi8]~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.~~il/oca-bin/ocashort?id=4BX4 OCA]~~.	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:023891291</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Pseudomonas phage phi8]]		[[Category: Pseudomonas phage phi8]]
-	[[Category: Bamford, D H.]]	+	[[Category: Bamford, D H]]
-	[[Category: Grimes, J M.]]	+	[[Category: Grimes, J M]]
-	[[Category: Mancini, E J.]]	+	[[Category: Mancini, E J]]
-	[[Category: Omari, K El.]]	+	[[Category: Omari, K El]]
-	[[Category: Ravantti, J J.]]	+	[[Category: Ravantti, J J]]
-	[[Category: Stuart, D I.]]	+	[[Category: Stuart, D I]]
-	[[Category: Sutton, G.]]	+	[[Category: Sutton, G]]
-	[[Category: Walter, T S.]]	+	[[Category: Walter, T S]]
-	[[Category: Zhang, H.]]	+	[[Category: Zhang, H]]
	[[Category: Bacteriophage]]		[[Category: Bacteriophage]]
	[[Category: Virus]]		[[Category: Virus]]

OCA at 20:54, 7 August 2013

2013-08-07T20:54:07Z

←Older revision		Revision as of 20:54, 7 August 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4bx4\| PDB=4bx4 \| SCENE= }}
		+	===Fitting of the bacteriophage Phi8 P1 capsid protein into cryo-EM density===
		+	{{ABSTRACT_PUBMED_23891291}}

-	~~The entry~~ 4bx4 is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
		+	[[4bx4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_phage_phi8 Pseudomonas phage phi8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BX4 OCA].

-	~~Authors~~: ~~El Omari~~, K., ~~Sutton~~, G., Ravantti, J.J., ~~Zhang, H~~., Walter, T.S., ~~Grimes, J.M., Bamford, D.~~H.~~, Stuart, D.I., Mancini, E.J.~~	+	==Reference==
-		+	<ref group="xtra">PMID:023891291</ref><references group="xtra"/><references/>
-	~~Description~~:	+	[[Category: Pseudomonas phage phi8]]
		+	[[Category: Bamford, D H.]]
		+	[[Category: Grimes, J M.]]
		+	[[Category: Mancini, E J.]]
		+	[[Category: Omari, K El.]]
		+	[[Category: Ravantti, J J.]]
		+	[[Category: Stuart, D I.]]
		+	[[Category: Sutton, G.]]
		+	[[Category: Walter, T S.]]
		+	[[Category: Zhang, H.]]
		+	[[Category: Bacteriophage]]
		+	[[Category: Virus]]

OCA: Protected "4bx4" [edit=sysop:move=sysop]

2013-07-18T04:41:22Z

Protected "4bx4" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:41, 18 July 2013