4c97 - Revision history

OCA at 12:06, 20 December 2023

2023-12-20T12:06:07Z

←Older revision		Revision as of 12:06, 20 December 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4c97]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C97 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C97 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4c97]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C97 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C97 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.7Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c97 OCA], [https://pdbe.org/4c97 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c97 RCSB], [https://www.ebi.ac.uk/pdbsum/4c97 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c97 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c97 OCA], [https://pdbe.org/4c97 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c97 RCSB], [https://www.ebi.ac.uk/pdbsum/4c97 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c97 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/Q5SM65_THET8 Q5SM65_THET8]]	+	[https://www.uniprot.org/uniprot/Q5SM65_THET8 Q5SM65_THET8]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In many bacteria and archaea, small RNAs derived from clustered regularly interspaced short palindromic repeats (CRISPRs) associate with CRISPR-associated (Cas) proteins to target foreign DNA for destruction. In Type I and III CRISPR/Cas systems, the Cas6 family of endoribonucleases generates functional CRISPR-derived RNAs by site-specific cleavage of repeat sequences in precursor transcripts. CRISPR repeats differ widely in both sequence and structure, with varying propensity to form hairpin folds immediately preceding the cleavage site. To investigate the evolution of distinct mechanisms for the recognition of diverse CRISPR repeats by Cas6 enzymes, we determined crystal structures of two Thermus thermophilus Cas6 enzymes both alone and bound to substrate and product RNAs. These structures show how the scaffold common to all Cas6 endonucleases has evolved two binding sites with distinct modes of RNA recognition: one specific for a hairpin fold and the other for a single-stranded 5'-terminal segment preceding the hairpin. These findings explain how divergent Cas6 enzymes have emerged to mediate highly selective pre-CRISPR-derived RNA processing across diverse CRISPR systems.
		+
		+	Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.,Niewoehner O, Jinek M, Doudna JA Nucleic Acids Res. 2013 Oct 22. PMID:24150936<ref>PMID:24150936</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 4c97" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[CRISPR-Cas Part II\|CRISPR-Cas Part II]]		*[[CRISPR-Cas Part II\|CRISPR-Cas Part II]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 17:33, 7 September 2022

2022-09-07T17:33:03Z

←Older revision		Revision as of 17:33, 7 September 2022
Line 3:		Line 3:
	<StructureSection load='4c97' size='340' side='right'caption='[[4c97]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='4c97' size='340' side='right'caption='[[4c97]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4c97]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Thet8 Thet8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C97 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4C97 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4c97]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C97 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C97 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4c8y\|4c8y]], [[4c8z\|4c8z]], [[4c98\|4c98]], [[4c9d\|4c9d]]~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c97 OCA], [https://pdbe.org/4c97 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c97 RCSB], [https://www.ebi.ac.uk/pdbsum/4c97 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c97 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4c97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c97 OCA], [~~http~~://pdbe.org/4c97 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4c97 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4c97 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4c97 ProSAT]</span></td></tr>	+
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[[https://www.uniprot.org/uniprot/Q5SM65_THET8 Q5SM65_THET8]]
-	In many bacteria and archaea, small RNAs derived from clustered regularly interspaced short palindromic repeats (CRISPRs) associate with CRISPR-associated (Cas) proteins to target foreign DNA for destruction. In Type I and III CRISPR/Cas systems, the Cas6 family of endoribonucleases generates functional CRISPR-derived RNAs by site-specific cleavage of repeat sequences in precursor transcripts. CRISPR repeats differ widely in both sequence and structure, with varying propensity to form hairpin folds immediately preceding the cleavage site. To investigate the evolution of distinct mechanisms for the recognition of diverse CRISPR repeats by Cas6 enzymes, we determined crystal structures of two Thermus thermophilus Cas6 enzymes both alone and bound to substrate and product RNAs. These structures show how the scaffold common to all Cas6 endonucleases has evolved two binding sites with distinct modes of RNA recognition: one specific for a hairpin fold and the other for a single-stranded 5'-terminal segment preceding the hairpin. These findings explain how divergent Cas6 enzymes have emerged to mediate highly selective pre-CRISPR-derived RNA processing across diverse CRISPR systems.	+
-		+
-	~~Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.,Niewoehner O, Jinek M, Doudna JA Nucleic Acids Res. 2013 Oct 22. PMID:24150936<ref>PMID:24150936<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®~~/~~PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 4c97" style="background-color:#fffaf0;"><~~/~~div>~~	+

	==See Also==		==See Also==
	*[[CRISPR-Cas Part II\|CRISPR-Cas Part II]]		*[[CRISPR-Cas Part II\|CRISPR-Cas Part II]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Thet8~~]]	+	[[Category: Thermus thermophilus HB8]]
-	[[Category: Doudna~~, J A~~]]	+	[[Category: Doudna JA]]
-	[[Category: Jinek, M]]	+	[[Category: Jinek M]]
-	[[Category: Niewoehner, O]]	+	[[Category: Niewoehner O]]
-	~~[[Category: Crispr cas protein rna processing ribonuclease]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 09:21, 20 March 2019

2019-03-20T09:21:47Z

←Older revision		Revision as of 09:21, 20 March 2019
Line 1:		Line 1:

	==Cas6 (TTHA0078) H37A mutant==		==Cas6 (TTHA0078) H37A mutant==
-	<StructureSection load='4c97' size='340' side='right' caption='[[4c97]], [[Resolution\|resolution]] 1.70Å' scene=''>	+	<StructureSection load='4c97' size='340' side='right'caption='[[4c97]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4c97]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C97 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C97 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4c97]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C97 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C97 FirstGlance]. <br>
Line 17:		Line 17:
	</div>		</div>
	<div class="pdbe-citations 4c97" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4c97" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[CRISPR-Cas Part II\|CRISPR-Cas Part II]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Thet8]]		[[Category: Thet8]]
	[[Category: Doudna, J A]]		[[Category: Doudna, J A]]

OCA at 15:25, 11 August 2016

2016-08-11T15:25:51Z

←Older revision		Revision as of 15:25, 11 August 2016
Line 1:		Line 1:
		+
	==Cas6 (TTHA0078) H37A mutant==		==Cas6 (TTHA0078) H37A mutant==
	<StructureSection load='4c97' size='340' side='right' caption='[[4c97]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='4c97' size='340' side='right' caption='[[4c97]], [[Resolution\|resolution]] 1.70Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4c8y\|4c8y]], [[4c8z\|4c8z]], [[4c98\|4c98]], [[4c9d\|4c9d]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4c8y\|4c8y]], [[4c8z\|4c8z]], [[4c98\|4c98]], [[4c9d\|4c9d]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c97 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c97 RCSB], [http://www.ebi.ac.uk/pdbsum/4c97 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c97 OCA], [http://pdbe.org/4c97 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4c97 RCSB], [http://www.ebi.ac.uk/pdbsum/4c97 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4c97 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4c97" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:48, 5 January 2015

2015-01-05T12:48:08Z

←Older revision		Revision as of 12:48, 5 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4c97]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C97 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C97 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4c97]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C97 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C97 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4c8y\|4c8y]], [[4c8z\|4c8z]], [[4c98\|4c98]], [[4c9d\|4c9d]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4c8y\|4c8y]], [[4c8z\|4c8z]], [[4c98\|4c98]], [[4c9d\|4c9d]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c97 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c97 RCSB], [http://www.ebi.ac.uk/pdbsum/4c97 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c97 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c97 RCSB], [http://www.ebi.ac.uk/pdbsum/4c97 PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 20:
	</StructureSection>		</StructureSection>
	[[Category: Thet8]]		[[Category: Thet8]]
-	[[Category: Doudna, J A.]]	+	[[Category: Doudna, J A]]
-	[[Category: Jinek, M.]]	+	[[Category: Jinek, M]]
-	[[Category: Niewoehner, O.]]	+	[[Category: Niewoehner, O]]
	[[Category: Crispr cas protein rna processing ribonuclease]]		[[Category: Crispr cas protein rna processing ribonuclease]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 06:46, 23 July 2014

2014-07-23T06:46:12Z

←Older revision		Revision as of 06:46, 23 July 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4c97~~\| ~~PDB~~=4c97 \| ~~SCENE~~= }}	+	==Cas6 (TTHA0078) H37A mutant==
-	===~~Cas6 (TTHA0078) H37A mutant~~===	+	<StructureSection load='4c97' size='340' side='right' caption='[[4c97]], [[Resolution\|resolution]] 1.70Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24150936}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4c97]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C97 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C97 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4c8y\|4c8y]], [[4c8z\|4c8z]], [[4c98\|4c98]], [[4c9d\|4c9d]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c97 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c97 RCSB], [http://www.ebi.ac.uk/pdbsum/4c97 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In many bacteria and archaea, small RNAs derived from clustered regularly interspaced short palindromic repeats (CRISPRs) associate with CRISPR-associated (Cas) proteins to target foreign DNA for destruction. In Type I and III CRISPR/Cas systems, the Cas6 family of endoribonucleases generates functional CRISPR-derived RNAs by site-specific cleavage of repeat sequences in precursor transcripts. CRISPR repeats differ widely in both sequence and structure, with varying propensity to form hairpin folds immediately preceding the cleavage site. To investigate the evolution of distinct mechanisms for the recognition of diverse CRISPR repeats by Cas6 enzymes, we determined crystal structures of two Thermus thermophilus Cas6 enzymes both alone and bound to substrate and product RNAs. These structures show how the scaffold common to all Cas6 endonucleases has evolved two binding sites with distinct modes of RNA recognition: one specific for a hairpin fold and the other for a single-stranded 5'-terminal segment preceding the hairpin. These findings explain how divergent Cas6 enzymes have emerged to mediate highly selective pre-CRISPR-derived RNA processing across diverse CRISPR systems.

-	~~==About this Structure==~~	+	Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.,Niewoehner O, Jinek M, Doudna JA Nucleic Acids Res. 2013 Oct 22. PMID:24150936<ref>PMID:24150936</ref>
-	~~[[4c97]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thet8 Thet8]~~. ~~Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4C97 OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:024150936</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Thet8]]		[[Category: Thet8]]
	[[Category: Doudna, J A.]]		[[Category: Doudna, J A.]]

OCA at 12:26, 20 November 2013

2013-11-20T12:26:04Z

←Older revision		Revision as of 12:26, 20 November 2013
Line 4:		Line 4:

	==About this Structure==		==About this Structure==
-	[[4c97]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermus_thermophilus_hb8 Thermus thermophilus hb8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C97 OCA].	+	[[4c97]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C97 OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:024150936</ref><references group="xtra"/><references/>		<ref group="xtra">PMID:024150936</ref><references group="xtra"/><references/>
-	[[Category: ~~Thermus thermophilus hb8~~]]	+	[[Category: Thet8]]
	[[Category: Doudna, J A.]]		[[Category: Doudna, J A.]]
	[[Category: Jinek, M.]]		[[Category: Jinek, M.]]

OCA at 07:39, 6 November 2013

2013-11-06T07:39:06Z

←Older revision		Revision as of 07:39, 6 November 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4c97\| PDB=4c97 \| SCENE= }}
		+	===Cas6 (TTHA0078) H37A mutant===
		+	{{ABSTRACT_PUBMED_24150936}}

-	~~The entry~~ 4c97 is ~~ON HOLD~~	+	==About this Structure==
		+	[[4c97]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C97 OCA].

-	~~Authors~~: Jinek, M., Niewoehner, O.~~, Doudna, J.A.~~	+	==Reference==
-		+	<ref group="xtra">PMID:024150936</ref><references group="xtra"/><references/>
-	~~Description~~: ~~Cas6 (TTHA0078) H37A mutant~~	+	[[Category: Thermus thermophilus hb8]]
		+	[[Category: Doudna, J A.]]
		+	[[Category: Jinek, M.]]
		+	[[Category: Niewoehner, O.]]
		+	[[Category: Crispr cas protein rna processing ribonuclease]]
		+	[[Category: Hydrolase]]

OCA: Protected "4c97" [edit=sysop:move=sysop]

2013-10-10T05:28:56Z

Protected "4c97" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:28, 10 October 2013

OCA: New page: '''Unreleased structure''' The entry 4c97 is ON HOLD Authors: Jinek, M., Niewoehner, O., Doudna, J.A. Description: Cas6 (TTHA0078) H37A mutant

2013-10-10T05:28:54Z

New page: '''Unreleased structure''' The entry 4c97 is ON HOLD Authors: Jinek, M., Niewoehner, O., Doudna, J.A. Description: Cas6 (TTHA0078) H37A mutant

New page

'''Unreleased structure'''

The entry 4c97 is ON HOLD

Authors: Jinek, M., Niewoehner, O., Doudna, J.A.

Description: Cas6 (TTHA0078) H37A mutant