4cd6 - Revision history

OCA at 12:08, 20 December 2023

2023-12-20T12:08:04Z

←Older revision		Revision as of 12:08, 20 December 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4cd6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alicyclobacillus_acidocaldarius Alicyclobacillus acidocaldarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CD6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CD6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4cd6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alicyclobacillus_acidocaldarius Alicyclobacillus acidocaldarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CD6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CD6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=IFM:5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE'>IFM</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.64Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=IFM:5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE'>IFM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cd6 OCA], [https://pdbe.org/4cd6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cd6 RCSB], [https://www.ebi.ac.uk/pdbsum/4cd6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cd6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cd6 OCA], [https://pdbe.org/4cd6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cd6 RCSB], [https://www.ebi.ac.uk/pdbsum/4cd6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cd6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/A5H1I6_9BACL A5H1I6_9BACL]]	+	[https://www.uniprot.org/uniprot/A5H1I6_9BACL A5H1I6_9BACL]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Mannosidases catalyze the hydrolysis of a diverse range of polysaccharides and glycoconjugates, and the various sequence-based mannosidase families have evolved ingenious strategies to overcome the stereoelectronic challenges of mannoside chemistry. Using a combination of computational chemistry, inhibitor design and synthesis, and X-ray crystallography of inhibitor/enzyme complexes, it is demonstrated that mannoimidazole-type inhibitors are energetically poised to report faithfully on mannosidase transition-state conformation, and provide direct evidence for the conformational itinerary used by diverse mannosidases, including beta-mannanases from families GH26 and GH113. Isofagomine-type inhibitors are poor mimics of transition-state conformation, owing to the high energy barriers that must be crossed to attain mechanistically relevant conformations, however, these sugar-shaped heterocycles allow the acquisition of ternary complexes that span the active site, thus providing valuable insight into active-site residues involved in substrate recognition.
		+
		+	Combined inhibitor free-energy landscape and structural analysis reports on the mannosidase conformational coordinate.,Williams RJ, Iglesias-Fernandez J, Stepper J, Jackson A, Thompson AJ, Lowe EC, White JM, Gilbert HJ, Rovira C, Davies GJ, Williams SJ Angew Chem Int Ed Engl. 2014 Jan 20;53(4):1087-91. doi: 10.1002/anie.201308334., Epub 2013 Dec 11. PMID:24339341<ref>PMID:24339341</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 4cd6" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 17:39, 7 September 2022

2022-09-07T17:39:51Z

←Older revision		Revision as of 17:39, 7 September 2022
Line 3:		Line 3:
	<StructureSection load='4cd6' size='340' side='right'caption='[[4cd6]], [[Resolution\|resolution]] 1.64Å' scene=''>		<StructureSection load='4cd6' size='340' side='right'caption='[[4cd6]], [[Resolution\|resolution]] 1.64Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4cd6]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_27009 Atcc 27009~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CD6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4CD6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4cd6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alicyclobacillus_acidocaldarius Alicyclobacillus acidocaldarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CD6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CD6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=IFM:5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE'>IFM</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=IFM:5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE'>IFM</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cd4\|4cd4]], [[4cd5\|4cd5]], [[4cd7\|4cd7]], [[4cd8\|4cd8]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cd6 OCA], [https://pdbe.org/4cd6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cd6 RCSB], [https://www.ebi.ac.uk/pdbsum/4cd6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cd6 ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4cd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cd6 OCA], [~~http~~://pdbe.org/4cd6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4cd6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4cd6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4cd6 ProSAT]</span></td></tr>	+
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[[https://www.uniprot.org/uniprot/A5H1I6_9BACL A5H1I6_9BACL]]
-	Mannosidases catalyze the hydrolysis of a diverse range of polysaccharides and glycoconjugates, and the various sequence-based mannosidase families have evolved ingenious strategies to overcome the stereoelectronic challenges of mannoside chemistry. Using a combination of computational chemistry, inhibitor design and synthesis, and X-ray crystallography of inhibitor/enzyme complexes, it is demonstrated that mannoimidazole-type inhibitors are energetically poised to report faithfully on mannosidase transition-state conformation, and provide direct evidence for the conformational itinerary used by diverse mannosidases, including beta-mannanases from families GH26 and GH113. Isofagomine-type inhibitors are poor mimics of transition-state conformation, owing to the high energy barriers that must be crossed to attain mechanistically relevant conformations, however, these sugar-shaped heterocycles allow the acquisition of ternary complexes that span the active site, thus providing valuable insight into active-site residues involved in substrate recognition.	+
-		+
-	Combined inhibitor free-energy landscape and structural analysis reports on the mannosidase conformational coordinate.,Williams RJ, Iglesias-Fernandez J, Stepper J, Jackson A, Thompson AJ, Lowe EC, White JM, Gilbert HJ, Rovira C, Davies GJ, Williams SJ Angew Chem Int Ed Engl. 2014 Jan 20;53(4):~~1087-91. doi: 10.1002~~/~~anie.201308334., Epub 2013 Dec 11. PMID:24339341<ref>PMID:24339341<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 4cd6" style="background-color:#fffaf0;"></div>~~	+
-	~~== References ==~~	+
-	~~<references~~/>	+
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 27009~~]]	+	[[Category: Alicyclobacillus acidocaldarius]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Mannan endo-1,4-beta-mannosidase]]~~	+	[[Category: Davies GJ]]
-	[[Category: Davies~~, G J~~]]	+	[[Category: Gilbert HJ]]
-	[[Category: Gilbert~~, H J~~]]	+	[[Category: Iglesias-Fernandez J]]
-	[[Category: Iglesias-Fernandez, J]]	+	[[Category: Jackson A]]
-	[[Category: Jackson, A]]	+	[[Category: Lowe EC]]
-	[[Category: Lowe~~, E C~~]]	+	[[Category: Rovira C]]
-	[[Category: Rovira, C]]	+	[[Category: Stepper J]]
-	[[Category: Stepper, J]]	+	[[Category: Thompson AJ]]
-	[[Category: Thompson~~, A J~~]]	+	[[Category: White JM]]
-	[[Category: White~~, J M~~]]	+	[[Category: Williams RJ]]
-	[[Category: Williams~~, R J~~]]	+	[[Category: Williams SJ]]
-	[[Category: Williams~~, S J]]~~	+
-	~~[[Category: Beta-mannosidase]]~~	+
-	~~[[Category: Biocatalysis]]~~	+
-	~~[[Category: Cazy]]~~	+
-	~~[[Category: Conformation]]~~	+
-	~~[[Category: Enzyme-carbohydrate interaction]]~~	+
-	~~[[Category: Gh113]]~~	+
-	~~[[Category: Gh26]]~~	+
-	~~[[Category: Glycosidase inhibition]]~~	+
-	~~[[Category: Glycoside hydrolase]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Mannosidase]]~~	+
-	~~[[Category: Quantum mechanic~~]]	+

OCA at 09:51, 20 March 2019

2019-03-20T09:51:38Z

←Older revision		Revision as of 09:51, 20 March 2019
Line 1:		Line 1:

	==The structure of GH113 beta-mannanase AaManA from Alicyclobacillus acidocaldarius in complex with ManIFG==		==The structure of GH113 beta-mannanase AaManA from Alicyclobacillus acidocaldarius in complex with ManIFG==
-	<StructureSection load='4cd6' size='340' side='right' caption='[[4cd6]], [[Resolution\|resolution]] 1.64Å' scene=''>	+	<StructureSection load='4cd6' size='340' side='right'caption='[[4cd6]], [[Resolution\|resolution]] 1.64Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4cd6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_27009 Atcc 27009]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CD6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CD6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4cd6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_27009 Atcc 27009]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CD6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CD6 FirstGlance]. <br>
Line 23:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 27009]]		[[Category: Atcc 27009]]
		+	[[Category: Large Structures]]
	[[Category: Mannan endo-1,4-beta-mannosidase]]		[[Category: Mannan endo-1,4-beta-mannosidase]]
	[[Category: Davies, G J]]		[[Category: Davies, G J]]

OCA at 13:28, 19 April 2017

2017-04-19T13:28:45Z

←Older revision		Revision as of 13:28, 19 April 2017
Line 1:		Line 1:
		+
	==The structure of GH113 beta-mannanase AaManA from Alicyclobacillus acidocaldarius in complex with ManIFG==		==The structure of GH113 beta-mannanase AaManA from Alicyclobacillus acidocaldarius in complex with ManIFG==
	<StructureSection load='4cd6' size='340' side='right' caption='[[4cd6]], [[Resolution\|resolution]] 1.64Å' scene=''>		<StructureSection load='4cd6' size='340' side='right' caption='[[4cd6]], [[Resolution\|resolution]] 1.64Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cd4\|4cd4]], [[4cd5\|4cd5]], [[4cd7\|4cd7]], [[4cd8\|4cd8]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cd4\|4cd4]], [[4cd5\|4cd5]], [[4cd7\|4cd7]], [[4cd8\|4cd8]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cd6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cd6 RCSB], [http://www.ebi.ac.uk/pdbsum/4cd6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cd6 OCA], [http://pdbe.org/4cd6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cd6 RCSB], [http://www.ebi.ac.uk/pdbsum/4cd6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cd6 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4cd6" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:20, 4 January 2015

2015-01-04T13:20:53Z

←Older revision		Revision as of 13:20, 4 January 2015
Line 1:		Line 1:
-	~~{{STRUCTURE_4cd6\| PDB=4cd6 \| SCENE= }}~~	+	==The structure of GH113 beta-mannanase AaManA from Alicyclobacillus acidocaldarius in complex with ManIFG==
-	===The structure of GH113 beta-mannanase AaManA from Alicyclobacillus acidocaldarius in complex with ManIFG===	+	<StructureSection load='4cd6' size='340' side='right' caption='[[4cd6]], [[Resolution\|resolution]] 1.64Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24339341}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4cd6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_27009 Atcc 27009]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CD6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CD6 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=IFM:5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE'>IFM</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cd4\|4cd4]], [[4cd5\|4cd5]], [[4cd7\|4cd7]], [[4cd8\|4cd8]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cd6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cd6 RCSB], [http://www.ebi.ac.uk/pdbsum/4cd6 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Mannosidases catalyze the hydrolysis of a diverse range of polysaccharides and glycoconjugates, and the various sequence-based mannosidase families have evolved ingenious strategies to overcome the stereoelectronic challenges of mannoside chemistry. Using a combination of computational chemistry, inhibitor design and synthesis, and X-ray crystallography of inhibitor/enzyme complexes, it is demonstrated that mannoimidazole-type inhibitors are energetically poised to report faithfully on mannosidase transition-state conformation, and provide direct evidence for the conformational itinerary used by diverse mannosidases, including beta-mannanases from families GH26 and GH113. Isofagomine-type inhibitors are poor mimics of transition-state conformation, owing to the high energy barriers that must be crossed to attain mechanistically relevant conformations, however, these sugar-shaped heterocycles allow the acquisition of ternary complexes that span the active site, thus providing valuable insight into active-site residues involved in substrate recognition.

-	~~==About this Structure==~~	+	Combined inhibitor free-energy landscape and structural analysis reports on the mannosidase conformational coordinate.,Williams RJ, Iglesias-Fernandez J, Stepper J, Jackson A, Thompson AJ, Lowe EC, White JM, Gilbert HJ, Rovira C, Davies GJ, Williams SJ Angew Chem Int Ed Engl. 2014 Jan 20;53(4):1087-91. doi: 10.1002/anie.201308334., Epub 2013 Dec 11. PMID:24339341<ref>PMID:24339341</ref>
-	~~[[4cd6]] is a 1 chain structure~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=4CD6 OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:024339341</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Atcc 27009]]
	[[Category: Mannan endo-1,4-beta-mannosidase]]		[[Category: Mannan endo-1,4-beta-mannosidase]]
-	[[Category: Davies, G J.]]	+	[[Category: Davies, G J]]
-	[[Category: Gilbert, H J.]]	+	[[Category: Gilbert, H J]]
-	[[Category: Iglesias-Fernandez, J.]]	+	[[Category: Iglesias-Fernandez, J]]
-	[[Category: Jackson, A.]]	+	[[Category: Jackson, A]]
-	[[Category: Lowe, E C.]]	+	[[Category: Lowe, E C]]
-	[[Category: Rovira, C.]]	+	[[Category: Rovira, C]]
-	[[Category: Stepper, J.]]	+	[[Category: Stepper, J]]
-	[[Category: Thompson, A J.]]	+	[[Category: Thompson, A J]]
-	[[Category: White, J M.]]	+	[[Category: White, J M]]
-	[[Category: Williams, R J.]]	+	[[Category: Williams, R J]]
-	[[Category: Williams, S J.]]	+	[[Category: Williams, S J]]
	[[Category: Beta-mannosidase]]		[[Category: Beta-mannosidase]]
	[[Category: Biocatalysis]]		[[Category: Biocatalysis]]

OCA at 09:14, 2 April 2014

2014-04-02T09:14:25Z

←Older revision		Revision as of 09:14, 2 April 2014
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_4cd6\| PDB=4cd6 \| SCENE= }}
		+	===The structure of GH113 beta-mannanase AaManA from Alicyclobacillus acidocaldarius in complex with ManIFG===
		+	{{ABSTRACT_PUBMED_24339341}}

-	~~The entry~~ 4cd6 is ~~ON HOLD~~	+	==About this Structure==
		+	[[4cd6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CD6 OCA].

-	~~Authors~~: ~~Williams~~, R.J., Iglesias-Fernandez, J.~~, Stepper, J.,~~ Jackson, A.~~, Thompson, A.J.,~~ Lowe, E.C.~~, White~~, J.~~M., Gilbert~~, H.J., ~~Rovira, C~~., ~~Davies, G.~~J., Williams, S.J.	+	==Reference==
-		+	<ref group="xtra">PMID:024339341</ref><references group="xtra"/><references/>
-	~~Description~~: ~~The structure of GH113 beta~~-~~mannanase AaManA from Alicyclobacillus acidocaldarius in complex with ManIFG~~	+	[[Category: Mannan endo-1,4-beta-mannosidase]]
		+	[[Category: Davies, G J.]]
		+	[[Category: Gilbert, H J.]]
		+	[[Category: Iglesias-Fernandez, J.]]
		+	[[Category: Jackson, A.]]
		+	[[Category: Lowe, E C.]]
		+	[[Category: Rovira, C.]]
		+	[[Category: Stepper, J.]]
		+	[[Category: Thompson, A J.]]
		+	[[Category: White, J M.]]
		+	[[Category: Williams, R J.]]
		+	[[Category: Williams, S J.]]
		+	[[Category: Beta-mannosidase]]
		+	[[Category: Biocatalysis]]
		+	[[Category: Cazy]]
		+	[[Category: Conformation]]
		+	[[Category: Enzyme-carbohydrate interaction]]
		+	[[Category: Gh113]]
		+	[[Category: Gh26]]
		+	[[Category: Glycosidase inhibition]]
		+	[[Category: Glycoside hydrolase]]
		+	[[Category: Hydrolase]]
		+	[[Category: Mannosidase]]
		+	[[Category: Quantum mechanic]]

OCA: Protected "4cd6" [edit=sysop:move=sysop]

2013-11-13T07:14:06Z

Protected "4cd6" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:14, 13 November 2013

OCA: New page: '''Unreleased structure''' The entry 4cd6 is ON HOLD Authors: Williams, R.J., Iglesias-Fernandez, J., Stepper, J., Jackson, A., Thompson, A.J., Lowe, E.C., White, J.M., Gilbert, H.J., R...

2013-11-13T07:14:04Z

New page: '''Unreleased structure''' The entry 4cd6 is ON HOLD Authors: Williams, R.J., Iglesias-Fernandez, J., Stepper, J., Jackson, A., Thompson, A.J., Lowe, E.C., White, J.M., Gilbert, H.J., R...

New page

'''Unreleased structure'''

The entry 4cd6 is ON HOLD

Authors: Williams, R.J., Iglesias-Fernandez, J., Stepper, J., Jackson, A., Thompson, A.J., Lowe, E.C., White, J.M., Gilbert, H.J., Rovira, C., Davies, G.J., Williams, S.J.

Description: The structure of GH113 beta-mannanase AaManA from Alicyclobacillus acidocaldarius in complex with ManIFG