4cnc - Revision history

OCA at 07:18, 1 May 2024

2024-05-01T07:18:37Z

←Older revision		Revision as of 07:18, 1 May 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4cnc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CNC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CNC FirstGlance]. <br>		<table><tr><td colspan='2'>[[4cnc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CNC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CNC FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.77Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cnc OCA], [https://pdbe.org/4cnc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cnc RCSB], [https://www.ebi.ac.uk/pdbsum/4cnc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cnc ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cnc OCA], [https://pdbe.org/4cnc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cnc RCSB], [https://www.ebi.ac.uk/pdbsum/4cnc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cnc ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/TPBG_HUMAN TPBG_HUMAN]]	+	[https://www.uniprot.org/uniprot/TPBG_HUMAN TPBG_HUMAN]
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	The tumor antigen 5T4/WAIF1 (Wnt-activated inhibitory factor 1; also known as Trophoblast glycoprotein TPBG) is a cell surface protein targeted in multiple cancer immunotherapy clinical trials. Recently, it has been shown that 5T4/WAIF1 inhibits Wnt/beta-catenin signaling, a signaling system central to many developmental and pathological processes. Wnt/beta-catenin signaling is controlled by multiple inhibitors and activators. Here, we report crystal structures for the extracellular domain of 5T4/WAIF1 at 1.8 A resolution. They reveal a highly glycosylated, rigid core, comprising eight leucine-rich repeats (LRRs), which serves as a platform to present evolutionarily conserved surface residues in the N-terminal LRR1. Structural and cell-based analyses, coupled with previously reported in vivo data, suggest that Tyr325 plus the LRR1 surface centered on a second exposed aromatic residue, Phe97, are essential for inhibition of Wnt/beta-catenin signaling. These results provide a structural basis for the development of 5T4/WAIF1-targeted therapies that preserve or block 5T4/WAIF1-mediated inhibition of Wnt/beta-catenin signaling.	+
-		+
-	Structural Insights into the Inhibition of Wnt Signaling by Cancer Antigen 5T4/Wnt-Activated Inhibitory Factor 1.,Zhao Y, Malinauskas T, Harlos K, Jones EY Structure. 2014 Feb 25. pii: S0969-2126(14)00037-9. doi:, 10.1016/j.str.2014.01.009. PMID:24582434<ref>PMID:24582434</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 4cnc" style="background-color:#fffaf0;"></div>~~	+
-	~~== References ==~~	+
-	~~<references/>~~	+
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 07:23, 14 September 2022

2022-09-14T07:23:17Z

←Older revision		Revision as of 07:23, 14 September 2022
Line 3:		Line 3:
	<StructureSection load='4cnc' size='340' side='right'caption='[[4cnc]], [[Resolution\|resolution]] 1.77Å' scene=''>		<StructureSection load='4cnc' size='340' side='right'caption='[[4cnc]], [[Resolution\|resolution]] 1.77Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4cnc]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CNC OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4CNC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4cnc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CNC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CNC FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cnm\|4cnm]]~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cnc OCA], [https://pdbe.org/4cnc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cnc RCSB], [https://www.ebi.ac.uk/pdbsum/4cnc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cnc ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4cnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cnc OCA], [~~http~~://pdbe.org/4cnc PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4cnc RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4cnc PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4cnc ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/TPBG_HUMAN TPBG_HUMAN]]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Harlos, K]]	+	[[Category: Harlos K]]
-	[[Category: Jones~~, E Y~~]]	+	[[Category: Jones EY]]
-	[[Category: Malinauskas, T]]	+	[[Category: Malinauskas T]]
-	[[Category: Zhao, Y]]	+	[[Category: Zhao Y]]
-	~~[[Category: Cancer]]~~	+
-	~~[[Category: Cell adhesion]]~~	+
-	~~[[Category: Leucine-rich repeat]]~~	+
-	~~[[Category: Signaling]]~~	+
-	~~[[Category: Tpbg]]~~	+
-	~~[[Category: Trovax]]~~	+
-	~~[[Category: Waif1]]~~	+
-	~~[[Category: Wnt/beta-catenin signaling pathway~~]]	+

OCA at 12:49, 10 May 2019

2019-05-10T12:49:39Z

←Older revision		Revision as of 12:49, 10 May 2019
Line 1:		Line 1:

	==Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)==		==Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)==
-	<StructureSection load='4cnc' size='340' side='right' caption='[[4cnc]], [[Resolution\|resolution]] 1.77Å' scene=''>	+	<StructureSection load='4cnc' size='340' side='right'caption='[[4cnc]], [[Resolution\|resolution]] 1.77Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4cnc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CNC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CNC FirstGlance]. <br>		<table><tr><td colspan='2'>[[4cnc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CNC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CNC FirstGlance]. <br>
Line 22:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Harlos, K]]		[[Category: Harlos, K]]
	[[Category: Jones, E Y]]		[[Category: Jones, E Y]]

OCA at 14:20, 11 August 2016

2016-08-11T14:20:21Z

←Older revision		Revision as of 14:20, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)==		==Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)==
	<StructureSection load='4cnc' size='340' side='right' caption='[[4cnc]], [[Resolution\|resolution]] 1.77Å' scene=''>		<StructureSection load='4cnc' size='340' side='right' caption='[[4cnc]], [[Resolution\|resolution]] 1.77Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cnm\|4cnm]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cnm\|4cnm]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cnc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cnc RCSB], [http://www.ebi.ac.uk/pdbsum/4cnc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cnc OCA], [http://pdbe.org/4cnc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cnc RCSB], [http://www.ebi.ac.uk/pdbsum/4cnc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cnc ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4cnc" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:31, 4 January 2015

2015-01-04T12:31:03Z

←Older revision		Revision as of 12:31, 4 January 2015
Line 1:		Line 1:
-	~~{{STRUCTURE_4cnc\| PDB=4cnc \| SCENE= }}~~	+	==Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)==
-	===Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)===	+	<StructureSection load='4cnc' size='340' side='right' caption='[[4cnc]], [[Resolution\|resolution]] 1.77Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24582434}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4cnc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CNC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CNC FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cnm\|4cnm]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cnc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cnc RCSB], [http://www.ebi.ac.uk/pdbsum/4cnc PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The tumor antigen 5T4/WAIF1 (Wnt-activated inhibitory factor 1; also known as Trophoblast glycoprotein TPBG) is a cell surface protein targeted in multiple cancer immunotherapy clinical trials. Recently, it has been shown that 5T4/WAIF1 inhibits Wnt/beta-catenin signaling, a signaling system central to many developmental and pathological processes. Wnt/beta-catenin signaling is controlled by multiple inhibitors and activators. Here, we report crystal structures for the extracellular domain of 5T4/WAIF1 at 1.8 A resolution. They reveal a highly glycosylated, rigid core, comprising eight leucine-rich repeats (LRRs), which serves as a platform to present evolutionarily conserved surface residues in the N-terminal LRR1. Structural and cell-based analyses, coupled with previously reported in vivo data, suggest that Tyr325 plus the LRR1 surface centered on a second exposed aromatic residue, Phe97, are essential for inhibition of Wnt/beta-catenin signaling. These results provide a structural basis for the development of 5T4/WAIF1-targeted therapies that preserve or block 5T4/WAIF1-mediated inhibition of Wnt/beta-catenin signaling.

-	~~==About this Structure==~~	+	Structural Insights into the Inhibition of Wnt Signaling by Cancer Antigen 5T4/Wnt-Activated Inhibitory Factor 1.,Zhao Y, Malinauskas T, Harlos K, Jones EY Structure. 2014 Feb 25. pii: S0969-2126(14)00037-9. doi:, 10.1016/j.str.2014.01.009. PMID:24582434<ref>PMID:24582434</ref>
-	~~[[4cnc]] is a 2 chain structure with sequence from [http:~~/~~/en~~.~~wikipedia~~.~~org/wiki/Human Human]~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.~~il/oca-bin/ocashort?id=4CNC OCA]~~.	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:024582434</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Human]]		[[Category: Human]]
-	[[Category: Harlos, K.]]	+	[[Category: Harlos, K]]
-	[[Category: Jones, E Y.]]	+	[[Category: Jones, E Y]]
-	[[Category: Malinauskas, T.]]	+	[[Category: Malinauskas, T]]
-	[[Category: Zhao, Y.]]	+	[[Category: Zhao, Y]]
	[[Category: Cancer]]		[[Category: Cancer]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]

OCA at 06:52, 23 April 2014

2014-04-23T06:52:51Z

←Older revision		Revision as of 06:52, 23 April 2014
Line 4:		Line 4:

	==About this Structure==		==About this Structure==
-	[[4cnc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CNC OCA].	+	[[4cnc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CNC OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:024582434</ref><references group="xtra"/><references/>		<ref group="xtra">PMID:024582434</ref><references group="xtra"/><references/>
		+	[[Category: Human]]
	[[Category: Harlos, K.]]		[[Category: Harlos, K.]]
	[[Category: Jones, E Y.]]		[[Category: Jones, E Y.]]

OCA at 13:50, 12 March 2014

2014-03-12T13:50:04Z

←Older revision		Revision as of 13:50, 12 March 2014
Line 1:		Line 1:
	{{STRUCTURE_4cnc\| PDB=4cnc \| SCENE= }}		{{STRUCTURE_4cnc\| PDB=4cnc \| SCENE= }}
	===Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)===		===Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)===
		+	{{ABSTRACT_PUBMED_24582434}}

	==About this Structure==		==About this Structure==
	[[4cnc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CNC OCA].		[[4cnc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CNC OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:024582434</ref><references group="xtra"/><references/>
	[[Category: Harlos, K.]]		[[Category: Harlos, K.]]
	[[Category: Jones, E Y.]]		[[Category: Jones, E Y.]]

OCA at 18:19, 3 March 2014

2014-03-03T18:19:13Z

←Older revision		Revision as of 18:19, 3 March 2014
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_4cnc\| PDB=4cnc \| SCENE= }}
		+	===Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)===

-	~~The entry~~ 4cnc is ~~ON HOLD~~	+	==About this Structure==
-		+	[[4cnc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CNC OCA].
-	~~Authors~~: ~~Zhao, Y~~.~~, Malinauskas, T~~., Harlos, K., Jones, E.Y.	+	[[Category: Harlos, K.]]
-		+	[[Category: Jones, E Y.]]
-	~~Description~~: ~~Crystal structure of human 5T4 (~~Wnt-~~activated inhibitory factor 1, Trophoblast glycoprotein)~~	+	[[Category: Malinauskas, T.]]
		+	[[Category: Zhao, Y.]]
		+	[[Category: Cancer]]
		+	[[Category: Cell adhesion]]
		+	[[Category: Leucine-rich repeat]]
		+	[[Category: Signaling]]
		+	[[Category: Tpbg]]
		+	[[Category: Trovax]]
		+	[[Category: Waif1]]
		+	[[Category: Wnt/beta-catenin signaling pathway]]

OCA: Protected "4cnc" [edit=sysop:move=sysop]

2014-01-29T06:46:41Z

Protected "4cnc" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:46, 29 January 2014

OCA: New page: '''Unreleased structure''' The entry 4cnc is ON HOLD Authors: Zhao, Y., Malinauskas, T., Harlos, K., Jones, E.Y. Description: Crystal structure of human 5T4 (Wnt-activated inhibitory f...

2014-01-29T06:46:39Z

New page: '''Unreleased structure''' The entry 4cnc is ON HOLD Authors: Zhao, Y., Malinauskas, T., Harlos, K., Jones, E.Y. Description: Crystal structure of human 5T4 (Wnt-activated inhibitory f...

New page

'''Unreleased structure'''

The entry 4cnc is ON HOLD

Authors: Zhao, Y., Malinauskas, T., Harlos, K., Jones, E.Y.

Description: Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)