4cvi - Revision history

OCA at 11:15, 9 May 2024

2024-05-09T11:15:07Z

←Older revision		Revision as of 11:15, 9 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4cvi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CVI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CVI FirstGlance]. <br>		<table><tr><td colspan='2'>[[4cvi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CVI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CVI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DOD:DEUTERATED+WATER'>DOD</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Hybrid , Neutron Diffraction , X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DOD:DEUTERATED+WATER'>DOD</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cvi OCA], [https://pdbe.org/4cvi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cvi RCSB], [https://www.ebi.ac.uk/pdbsum/4cvi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cvi ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cvi OCA], [https://pdbe.org/4cvi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cvi RCSB], [https://www.ebi.ac.uk/pdbsum/4cvi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cvi ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/CCPR_YEAST CCPR_YEAST]] Destroys radicals which are normally produced within the cells and which are toxic to biological systems.	+	[https://www.uniprot.org/uniprot/CCPR_YEAST CCPR_YEAST] Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 07:34, 14 September 2022

2022-09-14T07:34:32Z

←Older revision		Revision as of 07:34, 14 September 2022
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	<StructureSection load='4cvi' size='340' side='right'caption='[[4cvi]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='4cvi' size='340' side='right'caption='[[4cvi]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4cvi]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_18824 Atcc 18824~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CVI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4CVI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4cvi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CVI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CVI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DOD:DEUTERATED+WATER'>DOD</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DOD:DEUTERATED+WATER'>DOD</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cvj\|4cvj]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cvi OCA], [https://pdbe.org/4cvi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cvi RCSB], [https://www.ebi.ac.uk/pdbsum/4cvi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cvi ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytochrome-c_peroxidase Cytochrome-c peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.5 1.11.1.5] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4cvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cvi OCA], [~~http~~://pdbe.org/4cvi PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4cvi RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4cvi PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4cvi ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CCPR_YEAST CCPR_YEAST]] Destroys radicals which are normally produced within the cells and which are toxic to biological systems.	+	[[https://www.uniprot.org/uniprot/CCPR_YEAST CCPR_YEAST]] Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 18824]]
-	[[Category: Cytochrome-c peroxidase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Blakeley~~, M P~~]]	+	[[Category: Saccharomyces cerevisiae]]
-	[[Category: Casadei~~, C M~~]]	+	[[Category: Blakeley MP]]
-	[[Category: Gumiero, A]]	+	[[Category: Casadei CM]]
-	[[Category: Moody~~, P C.E~~]]	+	[[Category: Gumiero A]]
-	[[Category: Ostermann, A]]	+	[[Category: Moody PCE]]
-	[[Category: Raven~~, E L]]~~	+	[[Category: Ostermann A]]
-	~~[[Category: Electron transport]]~~	+	[[Category: Raven EL]]
-	~~[[Category: Ferric]]~~	+
-	~~[[Category: Heme]]~~	+
-	~~[[Category: Heme peroxidase]]~~	+
-	~~[[Category: Neutron]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Redox~~]]	+

OCA at 08:38, 11 March 2020

2020-03-11T08:38:21Z

←Older revision		Revision as of 08:38, 11 March 2020
Line 1:		Line 1:

	==Neutron Structure of Ferric Cytochrome c Peroxidase - Deuterium exchanged at room temperature==		==Neutron Structure of Ferric Cytochrome c Peroxidase - Deuterium exchanged at room temperature==
-	<StructureSection load='4cvi' size='340' side='right' caption='[[4cvi]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='4cvi' size='340' side='right'caption='[[4cvi]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4cvi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CVI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CVI FirstGlance]. <br>		<table><tr><td colspan='2'>[[4cvi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CVI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CVI FirstGlance]. <br>
Line 22:		Line 22:

	==See Also==		==See Also==
-	*[[Cytochrome c peroxidase\|Cytochrome c peroxidase]]	+	*[[Cytochrome c peroxidase 3D structures\|Cytochrome c peroxidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 29:		Line 29:
	[[Category: Atcc 18824]]		[[Category: Atcc 18824]]
	[[Category: Cytochrome-c peroxidase]]		[[Category: Cytochrome-c peroxidase]]
		+	[[Category: Large Structures]]
	[[Category: Blakeley, M P]]		[[Category: Blakeley, M P]]
	[[Category: Casadei, C M]]		[[Category: Casadei, C M]]

OCA at 06:07, 6 June 2018

2018-06-06T06:07:50Z

←Older revision		Revision as of 06:07, 6 June 2018
Line 3:		Line 3:
	<StructureSection load='4cvi' size='340' side='right' caption='[[4cvi]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='4cvi' size='340' side='right' caption='[[4cvi]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4cvi]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CVI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CVI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4cvi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CVI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CVI FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DOD:DEUTERATED+WATER'>DOD</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DOD:DEUTERATED+WATER'>DOD</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cvj\|4cvj]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cvj\|4cvj]]</td></tr>
Line 20:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 4cvi" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4cvi" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Cytochrome c peroxidase\|Cytochrome c peroxidase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 18824]]
	[[Category: Cytochrome-c peroxidase]]		[[Category: Cytochrome-c peroxidase]]
	[[Category: Blakeley, M P]]		[[Category: Blakeley, M P]]

OCA at 12:32, 6 November 2017

2017-11-06T12:32:27Z

←Older revision		Revision as of 12:32, 6 November 2017
Line 20:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 4cvi" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4cvi" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Cytochrome c peroxidase\|Cytochrome c peroxidase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 21:30, 5 August 2016

2016-08-05T21:30:28Z

←Older revision		Revision as of 21:30, 5 August 2016
Line 1:		Line 1:
		+
	==Neutron Structure of Ferric Cytochrome c Peroxidase - Deuterium exchanged at room temperature==		==Neutron Structure of Ferric Cytochrome c Peroxidase - Deuterium exchanged at room temperature==
	<StructureSection load='4cvi' size='340' side='right' caption='[[4cvi]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='4cvi' size='340' side='right' caption='[[4cvi]], [[Resolution\|resolution]] 2.10Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cvj\|4cvj]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cvj\|4cvj]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytochrome-c_peroxidase Cytochrome-c peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.5 1.11.1.5] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytochrome-c_peroxidase Cytochrome-c peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.5 1.11.1.5] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cvi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cvi RCSB], [http://www.ebi.ac.uk/pdbsum/4cvi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cvi OCA], [http://pdbe.org/4cvi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cvi RCSB], [http://www.ebi.ac.uk/pdbsum/4cvi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cvi ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4cvi" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Cytochrome c peroxidase\|Cytochrome c peroxidase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 22:04, 25 December 2014

2014-12-25T22:04:17Z

←Older revision		Revision as of 22:04, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cvi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cvi RCSB], [http://www.ebi.ac.uk/pdbsum/4cvi PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cvi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cvi RCSB], [http://www.ebi.ac.uk/pdbsum/4cvi PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CCPR_YEAST CCPR_YEAST]] Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Cytochrome-c peroxidase]]		[[Category: Cytochrome-c peroxidase]]
-	[[Category: Blakeley, M P.]]	+	[[Category: Blakeley, M P]]
-	[[Category: Casadei, C M.]]	+	[[Category: Casadei, C M]]
-	[[Category: Gumiero, A.]]	+	[[Category: Gumiero, A]]
-	[[Category: Moody, P C.E.]]	+	[[Category: Moody, P C.E]]
-	[[Category: Ostermann, A.]]	+	[[Category: Ostermann, A]]
-	[[Category: Raven, E L.]]	+	[[Category: Raven, E L]]
	[[Category: Electron transport]]		[[Category: Electron transport]]
	[[Category: Ferric]]		[[Category: Ferric]]

OCA at 08:48, 22 October 2014

2014-10-22T08:48:50Z

←Older revision		Revision as of 08:48, 22 October 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4cvi]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CVI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CVI FirstGlance]. <br>		<table><tr><td colspan='2'>[[4cvi]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CVI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CVI FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DOD:DEUTERATED+WATER'>DOD</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DOD:DEUTERATED+WATER'>DOD</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cvj\|4cvj]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cvj\|4cvj]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytochrome-c_peroxidase Cytochrome-c peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.5 1.11.1.5] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytochrome-c_peroxidase Cytochrome-c peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.5 1.11.1.5] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cvi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cvi RCSB], [http://www.ebi.ac.uk/pdbsum/4cvi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cvi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cvi RCSB], [http://www.ebi.ac.uk/pdbsum/4cvi PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Heme enzymes activate oxygen through formation of transient iron-oxo (ferryl) intermediates of the heme iron. A long-standing question has been the nature of the iron-oxygen bond and, in particular, the protonation state. We present neutron structures of the ferric derivative of cytochrome c peroxidase and its ferryl intermediate; these allow direct visualization of protonation states. We demonstrate that the ferryl heme is an Fe(IV)=O species and is not protonated. Comparison of the structures shows that the distal histidine becomes protonated on formation of the ferryl intermediate, which has implications for the understanding of O-O bond cleavage in heme enzymes. The structures highlight the advantages of neutron cryo-crystallography in probing reaction mechanisms and visualizing protonation states in enzyme intermediates.
		+
		+	Heme enzymes. Neutron cryo-crystallography captures the protonation state of ferryl heme in a peroxidase.,Casadei CM, Gumiero A, Metcalfe CL, Murphy EJ, Basran J, Concilio MG, Teixeira SC, Schrader TE, Fielding AJ, Ostermann A, Blakeley MP, Raven EL, Moody PC Science. 2014 Jul 11;345(6193):193-7. doi: 10.1126/science.1254398. Epub 2014 Jul, 10. PMID:25013070<ref>PMID:25013070</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 10:25, 16 July 2014

2014-07-16T10:25:46Z

←Older revision		Revision as of 10:25, 16 July 2014
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-	'''~~Unreleased structure~~'''	+	==Neutron Structure of Ferric Cytochrome c Peroxidase - Deuterium exchanged at room temperature==
-		+	<StructureSection load='4cvi' size='340' side='right' caption='[[4cvi]], [[Resolution\|resolution]] 2.10Å' scene=''>
-	~~The entry~~ 4cvi is ~~ON HOLD~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4cvi]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CVI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CVI FirstGlance]. <br>
-	~~Authors~~: ~~Casadei~~, C.M., ~~Gumiero~~, A., Blakeley, M.P., ~~Ostermann~~, A.~~, Raven, E.L.,~~ Moody, P.C.E.	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DOD:DEUTERATED+WATER'>DOD</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cvj\|4cvj]]</td></tr>
-	~~Description~~: ~~Neutron Structure of~~ Ferric ~~Cytochrome c Peroxidase -Deuterium exchanged at room temperature~~	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytochrome-c_peroxidase Cytochrome-c peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.5 1.11.1.5] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cvi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cvi RCSB], [http://www.ebi.ac.uk/pdbsum/4cvi PDBsum]</span></td></tr>
		+	<table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Cytochrome-c peroxidase]]
		+	[[Category: Blakeley, M P.]]
		+	[[Category: Casadei, C M.]]
		+	[[Category: Gumiero, A.]]
		+	[[Category: Moody, P C.E.]]
		+	[[Category: Ostermann, A.]]
		+	[[Category: Raven, E L.]]
		+	[[Category: Electron transport]]
		+	[[Category: Ferric]]
		+	[[Category: Heme]]
		+	[[Category: Heme peroxidase]]
		+	[[Category: Neutron]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Redox]]

OCA at 05:36, 9 April 2014

2014-04-09T05:36:22Z

←Older revision		Revision as of 05:36, 9 April 2014
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4cvi is ON HOLD ~~until sometime in the future~~	+	The entry 4cvi is ON HOLD

	Authors: Casadei, C.M., Gumiero, A., Blakeley, M.P., Ostermann, A., Raven, E.L., Moody, P.C.E.		Authors: Casadei, C.M., Gumiero, A., Blakeley, M.P., Ostermann, A., Raven, E.L., Moody, P.C.E.

	Description: Neutron Structure of Ferric Cytochrome c Peroxidase -Deuterium exchanged at room temperature		Description: Neutron Structure of Ferric Cytochrome c Peroxidase -Deuterium exchanged at room temperature