4d44 - Revision history

OCA at 12:20, 20 December 2023

2023-12-20T12:20:30Z

←Older revision		Revision as of 12:20, 20 December 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4d44]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_N315 Staphylococcus aureus subsp. aureus N315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D44 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D44 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4d44]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_N315 Staphylococcus aureus subsp. aureus N315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D44 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D44 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=JA3:5-ETHYL-4-FLUORO-2-[(2-FLUOROPYRIDIN-3-YL)OXY]PHENOL'>JA3</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=JA3:5-ETHYL-4-FLUORO-2-[(2-FLUOROPYRIDIN-3-YL)OXY]PHENOL'>JA3</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d44 OCA], [https://pdbe.org/4d44 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d44 RCSB], [https://www.ebi.ac.uk/pdbsum/4d44 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d44 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d44 OCA], [https://pdbe.org/4d44 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d44 RCSB], [https://www.ebi.ac.uk/pdbsum/4d44 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d44 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/A0A0J9X1Y0_STAAN A0A0J9X1Y0_STAAN]]	+	[https://www.uniprot.org/uniprot/A0A0J9X1Y0_STAAN A0A0J9X1Y0_STAAN]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 07:46, 14 September 2022

2022-09-14T07:46:09Z

←Older revision		Revision as of 07:46, 14 September 2022
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	<StructureSection load='4d44' size='340' side='right'caption='[[4d44]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='4d44' size='340' side='right'caption='[[4d44]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4d44]] is a 8 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Staan Staan~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D44 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4D44 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4d44]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_N315 Staphylococcus aureus subsp. aureus N315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D44 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D44 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=JA3:5-ETHYL-4-FLUORO-2-[(2-FLUOROPYRIDIN-3-YL)OXY]PHENOL'>JA3</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=JA3:5-ETHYL-4-FLUORO-2-[(2-FLUOROPYRIDIN-3-YL)OXY]PHENOL'>JA3</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d41\|4d41]], [[4d42\|4d42]], [[4d43\|4d43]], [[4d45\|4d45]], [[4d46\|4d46]]~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d44 OCA], [https://pdbe.org/4d44 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d44 RCSB], [https://www.ebi.ac.uk/pdbsum/4d44 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d44 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4d44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d44 OCA], [~~http~~://pdbe.org/4d44 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4d44 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4d44 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4d44 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/A0A0J9X1Y0_STAAN A0A0J9X1Y0_STAAN]]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	==See Also==		==See Also==
-	*[[Enoyl-Acyl-Carrier Protein Reductase\|Enoyl-Acyl-Carrier Protein Reductase]]	+	*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures\|Enoyl-Acyl-Carrier Protein Reductase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Staan~~]]	+	[[Category: Staphylococcus aureus subsp. aureus N315]]
-	[[Category: Chang, A]]	+	[[Category: Chang A]]
-	[[Category: Kisker, C]]	+	[[Category: Kisker C]]
-	[[Category: Schiebel, J]]	+	[[Category: Schiebel J]]
-	[[Category: Sotriffer~~, C A~~]]	+	[[Category: Sotriffer CA]]
-	[[Category: Tonge~~, P J]]~~	+	[[Category: Tonge PJ]]
-	~~[[Category: Fabi]]~~	+
-	~~[[Category: Fatty acid biosynthesis]]~~	+
-	~~[[Category: Lipid synthesis]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Safabi]]~~	+
-	~~[[Category: Short-chain dehydrogenase/reductase superfamily~~]]	+

OCA at 09:40, 20 March 2019

2019-03-20T09:40:01Z

←Older revision		Revision as of 09:40, 20 March 2019
Line 1:		Line 1:

	==Crystal structure of S. aureus FabI in complex with NADP and 5-ethyl- 4-fluoro-2-((2-fluoropyridin-3-yl)oxy)phenol==		==Crystal structure of S. aureus FabI in complex with NADP and 5-ethyl- 4-fluoro-2-((2-fluoropyridin-3-yl)oxy)phenol==
-	<StructureSection load='4d44' size='340' side='right' caption='[[4d44]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='4d44' size='340' side='right'caption='[[4d44]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4d44]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D44 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D44 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4d44]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Staan Staan]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D44 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D44 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=JA3:5-ETHYL-4-FLUORO-2-[(2-FLUOROPYRIDIN-3-YL)OXY]PHENOL'>JA3</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=JA3:5-ETHYL-4-FLUORO-2-[(2-FLUOROPYRIDIN-3-YL)OXY]PHENOL'>JA3</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d41\|4d41]], [[4d42\|4d42]], [[4d43\|4d43]], [[4d45\|4d45]], [[4d46\|4d46]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d41\|4d41]], [[4d42\|4d42]], [[4d43\|4d43]], [[4d45\|4d45]], [[4d46\|4d46]]</td></tr>
Line 24:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Staan]]
	[[Category: Chang, A]]		[[Category: Chang, A]]
	[[Category: Kisker, C]]		[[Category: Kisker, C]]

OCA at 17:25, 18 January 2017

2017-01-18T17:25:30Z

←Older revision		Revision as of 17:25, 18 January 2017
Line 1:		Line 1:
		+
	==Crystal structure of S. aureus FabI in complex with NADP and 5-ethyl- 4-fluoro-2-((2-fluoropyridin-3-yl)oxy)phenol==		==Crystal structure of S. aureus FabI in complex with NADP and 5-ethyl- 4-fluoro-2-((2-fluoropyridin-3-yl)oxy)phenol==
	<StructureSection load='4d44' size='340' side='right' caption='[[4d44]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='4d44' size='340' side='right' caption='[[4d44]], [[Resolution\|resolution]] 1.80Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=JA3:5-ETHYL-4-FLUORO-2-[(2-FLUOROPYRIDIN-3-YL)OXY]PHENOL'>JA3</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=JA3:5-ETHYL-4-FLUORO-2-[(2-FLUOROPYRIDIN-3-YL)OXY]PHENOL'>JA3</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d41\|4d41]], [[4d42\|4d42]], [[4d43\|4d43]], [[4d45\|4d45]], [[4d46\|4d46]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d41\|4d41]], [[4d42\|4d42]], [[4d43\|4d43]], [[4d45\|4d45]], [[4d46\|4d46]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d44 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d44 RCSB], [http://www.ebi.ac.uk/pdbsum/4d44 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d44 OCA], [http://pdbe.org/4d44 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4d44 RCSB], [http://www.ebi.ac.uk/pdbsum/4d44 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4d44 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4d44" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 06:44, 15 April 2015

2015-04-15T06:44:24Z

←Older revision		Revision as of 06:44, 15 April 2015
Line 15:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+
		+	==See Also==
		+	*[[Enoyl-Acyl-Carrier Protein Reductase\|Enoyl-Acyl-Carrier Protein Reductase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:28, 4 March 2015

2015-03-04T11:28:41Z

←Older revision		Revision as of 11:28, 4 March 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal structure of S. aureus FabI in complex with NADP and 5-ethyl- 4-fluoro-2-((2-fluoropyridin-3-yl)oxy)phenol==
		+	<StructureSection load='4d44' size='340' side='right' caption='[[4d44]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4d44]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D44 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D44 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=JA3:5-ETHYL-4-FLUORO-2-[(2-FLUOROPYRIDIN-3-YL)OXY]PHENOL'>JA3</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d41\|4d41]], [[4d42\|4d42]], [[4d43\|4d43]], [[4d45\|4d45]], [[4d46\|4d46]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d44 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d44 RCSB], [http://www.ebi.ac.uk/pdbsum/4d44 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	One third of all drugs in clinical use owe their pharmacological activity to the functional inhibition of enzymes, highlighting the importance of enzymatic targets for drug development. Because of the close relationship between inhibition and catalysis, understanding the recognition and turnover of enzymatic substrates is essential for rational drug design. Although the Staphylococcus aureus enoyl-acyl carrier protein reductase (saFabI) involved in bacterial fatty acid biosynthesis constitutes a very promising target for the development of novel, urgently needed anti-staphylococcal agents, the substrate binding mode and catalytic mechanism remained unclear for this enzyme. Using a combined crystallographic, kinetic, and computational approach, we have explored the chemical properties of the saFabI binding cavity, obtaining a consistent mechanistic model for substrate binding and turnover. We identified a water-molecule network linking the active site with a water basin inside the homo-tetrameric protein, which seems to be crucial for the closure of the flexible substrate binding loop as well as for an effective hydride and proton transfer during catalysis. On the basis of our results, we also derive a new model for the FabI-ACP complex that reveals how the ACP-bound acyl-substrate is injected into the FabI binding crevice. These findings support the future development of novel FabI inhibitors that target the FabI-ACP interface leading to the disruption of the interaction between these two proteins.

-	~~The entry 4d44 is ON HOLD until Paper Publication~~	+	An Ordered Water Channel in Staphylococcus aureus FabI: Unraveling the Mechanism of Substrate Recognition and Reduction.,Schiebel J, Chang A, Merget B, Bommineni GR, Yu W, Spagnuolo LA, Baxter MV, Tareilus M, Tonge PJ, Kisker C, Sotriffer CA Biochemistry. 2015 Mar 3. PMID:25706582<ref>PMID:25706582</ref>

-	~~Authors: Schiebel~~, J.~~, Chang, A~~.~~, Tonge, P.J., Sotriffer, C.A., Kisker, C~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: Crystal structure of S. aureus FabI in complex with NADP and 5-ethyl-4-fluoro-2-((2-fluoropyridin-3-yl)oxy)phenol~~	+	== References ==
-	~~[[Category: Unreleased Structures]]~~	+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Chang, A]]		[[Category: Chang, A]]
		+	[[Category: Kisker, C]]
	[[Category: Schiebel, J]]		[[Category: Schiebel, J]]
-	[[Category: ~~Kisker~~, C]]	+	[[Category: Sotriffer, C A]]
-	[[Category: ~~Sotriffer~~, ~~C.A~~]]	+	[[Category: Tonge, P J]]
-	[[Category: ~~Tonge, P.J~~]]	+	[[Category: Fabi]]
		+	[[Category: Fatty acid biosynthesis]]
		+	[[Category: Lipid synthesis]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Safabi]]
		+	[[Category: Short-chain dehydrogenase/reductase superfamily]]

OCA at 13:45, 24 December 2014

2014-12-24T13:45:14Z

←Older revision		Revision as of 13:45, 24 December 2014
Line 6:		Line 6:

	Description: Crystal structure of S. aureus FabI in complex with NADP and 5-ethyl-4-fluoro-2-((2-fluoropyridin-3-yl)oxy)phenol		Description: Crystal structure of S. aureus FabI in complex with NADP and 5-ethyl-4-fluoro-2-((2-fluoropyridin-3-yl)oxy)phenol
		+	[[Category: Unreleased Structures]]
		+	[[Category: Chang, A]]
		+	[[Category: Schiebel, J]]
		+	[[Category: Kisker, C]]
		+	[[Category: Sotriffer, C.A]]
		+	[[Category: Tonge, P.J]]

OCA: Protected "4d44" [edit=sysop:move=sysop]

2014-11-05T07:19:51Z

Protected "4d44" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:19, 5 November 2014

OCA: New page: '''Unreleased structure''' The entry 4d44 is ON HOLD until Paper Publication Authors: Schiebel, J., Chang, A., Tonge, P.J., Sotriffer, C.A., Kisker, C. Description: Crystal structure o...

2014-11-05T07:19:50Z

New page: '''Unreleased structure''' The entry 4d44 is ON HOLD until Paper Publication Authors: Schiebel, J., Chang, A., Tonge, P.J., Sotriffer, C.A., Kisker, C. Description: Crystal structure o...

New page

'''Unreleased structure'''

The entry 4d44 is ON HOLD until Paper Publication

Authors: Schiebel, J., Chang, A., Tonge, P.J., Sotriffer, C.A., Kisker, C.

Description: Crystal structure of S. aureus FabI in complex with NADP and 5-ethyl-4-fluoro-2-((2-fluoropyridin-3-yl)oxy)phenol