4d8u - Revision history

OCA at 13:41, 8 November 2023

2023-11-08T13:41:48Z

←Older revision		Revision as of 13:41, 8 November 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4d8u]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D8U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D8U FirstGlance]. <br>		<table><tr><td colspan='2'>[[4d8u]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D8U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D8U FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.3Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d8u OCA], [https://pdbe.org/4d8u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d8u RCSB], [https://www.ebi.ac.uk/pdbsum/4d8u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d8u ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d8u OCA], [https://pdbe.org/4d8u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d8u RCSB], [https://www.ebi.ac.uk/pdbsum/4d8u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d8u ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/DCYD_SALTY DCYD_SALTY]] Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine.[HAMAP-Rule:MF_01045]	+	[https://www.uniprot.org/uniprot/DCYD_SALTY DCYD_SALTY] Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine.[HAMAP-Rule:MF_01045]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 07:52, 14 September 2022

2022-09-14T07:52:53Z

←Older revision		Revision as of 07:52, 14 September 2022
Line 3:		Line 3:
	<StructureSection load='4d8u' size='340' side='right'caption='[[4d8u]], [[Resolution\|resolution]] 3.30Å' scene=''>		<StructureSection load='4d8u' size='340' side='right'caption='[[4d8u]], [[Resolution\|resolution]] 3.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4d8u]] is a 8 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D8U OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4D8U FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4d8u]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D8U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D8U FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	~~<tr~~ id~~='NonStdRes'><td class~~="~~sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat~~"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>~~</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d8u OCA], [https://pdbe.org/4d8u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d8u RCSB], [https://www.ebi.ac.uk/pdbsum/4d8u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d8u ProSAT]</span></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d8t\|4d8t]]~~, ~~[[4d8w\|4d8w]], [[4d92\|4d92]], [[4d96\|4d96]], [[4d97\|4d97]], [[4d99\|4d99]], [[4d9b\|4d9b]], [[4d9c\|4d9c]], [[4d9e\|4d9e]], [[4d9f\|4d9f]]~~<~~/td></tr>~~	+
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b></td><td class="sblockDat">dcyD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>~~	+
-	~~<tr id='activity~~'>~~<td class="sblockLbl"><b>Activity:~~</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/D-cysteine_desulfhydrase D-cysteine desulfhydrase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.15 4.4.1.15] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4d8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d8u OCA], [~~http~~://pdbe.org/4d8u PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4d8u RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4d8u PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4d8u ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/DCYD_SALTY DCYD_SALTY]] Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine.[HAMAP-Rule:MF_01045]	+	[[https://www.uniprot.org/uniprot/DCYD_SALTY DCYD_SALTY]] Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine.[HAMAP-Rule:MF_01045]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus typhimurium loeffler 1892]]
-	[[Category: D-cysteine desulfhydrase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Bharath, S R]]~~	+	[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
-	~~[[Category: Murthy, M R~~.N]]	+	[[Category: Bharath SR]]
-	[[Category: ~~Rajesh, K H~~]]	+	[[Category: Murthy MRN]]
-	[[Category: ~~Savithri, H S~~]]	+	[[Category: Rajesh KH]]
-	[[Category: ~~Shveta, B~~]]	+	[[Category: Savithri HS]]
-	[[Category: ~~Fold type ii plp-dependent enzyme~~]]	+	[[Category: Shveta B]]
-	[[Category: ~~Lyase]]~~	+
-	~~[[Category: Tryptophan synthase beta subunit-like plp-dependent enzymes superfamily~~]]	+

OCA at 07:27, 27 March 2019

2019-03-27T07:27:51Z

←Older revision		Revision as of 07:27, 27 March 2019
Line 1:		Line 1:

	==Crystal structure of D-Cysteine desulfhydrase from Salmonella typhimurium at 3.3 A in monoclinic space group with 8 subunits in the asymmetric unit==		==Crystal structure of D-Cysteine desulfhydrase from Salmonella typhimurium at 3.3 A in monoclinic space group with 8 subunits in the asymmetric unit==
-	<StructureSection load='4d8u' size='340' side='right' caption='[[4d8u]], [[Resolution\|resolution]] 3.30Å' scene=''>	+	<StructureSection load='4d8u' size='340' side='right'caption='[[4d8u]], [[Resolution\|resolution]] 3.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4d8u]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D8U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D8U FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4d8u]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D8U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D8U FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d8t\|4d8t]], [[4d8w\|4d8w]], [[4d92\|4d92]], [[4d96\|4d96]], [[4d97\|4d97]], [[4d99\|4d99]], [[4d9b\|4d9b]], [[4d9c\|4d9c]], [[4d9e\|4d9e]], [[4d9f\|4d9f]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d8t\|4d8t]], [[4d8w\|4d8w]], [[4d92\|4d92]], [[4d96\|4d96]], [[4d97\|4d97]], [[4d99\|4d99]], [[4d9b\|4d9b]], [[4d9c\|4d9c]], [[4d9e\|4d9e]], [[4d9f\|4d9f]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dcyD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/D-cysteine_desulfhydrase D-cysteine desulfhydrase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.15 4.4.1.15] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/D-cysteine_desulfhydrase D-cysteine desulfhydrase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.15 4.4.1.15] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d8u OCA], [http://pdbe.org/4d8u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4d8u RCSB], [http://www.ebi.ac.uk/pdbsum/4d8u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4d8u ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d8u OCA], [http://pdbe.org/4d8u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4d8u RCSB], [http://www.ebi.ac.uk/pdbsum/4d8u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4d8u ProSAT]</span></td></tr>
Line 25:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacillus typhimurium loeffler 1892]]
	[[Category: D-cysteine desulfhydrase]]		[[Category: D-cysteine desulfhydrase]]
		+	[[Category: Large Structures]]
	[[Category: Bharath, S R]]		[[Category: Bharath, S R]]
	[[Category: Murthy, M R.N]]		[[Category: Murthy, M R.N]]

OCA at 06:20, 10 May 2017

2017-05-10T06:20:07Z

←Older revision		Revision as of 06:20, 10 May 2017
Line 3:		Line 3:
	<StructureSection load='4d8u' size='340' side='right' caption='[[4d8u]], [[Resolution\|resolution]] 3.30Å' scene=''>		<StructureSection load='4d8u' size='340' side='right' caption='[[4d8u]], [[Resolution\|resolution]] 3.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4d8u]] is a 8 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D8U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D8U FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4d8u]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D8U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D8U FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~IT1~~:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>~~IT1~~</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d8t\|4d8t]], [[4d8w\|4d8w]], [[4d92\|4d92]], [[4d96\|4d96]], [[4d97\|4d97]], [[4d99\|4d99]], [[4d9b\|4d9b]], [[4d9c\|4d9c]], [[4d9e\|4d9e]], [[4d9f\|4d9f]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d8t\|4d8t]], [[4d8w\|4d8w]], [[4d92\|4d92]], [[4d96\|4d96]], [[4d97\|4d97]], [[4d99\|4d99]], [[4d9b\|4d9b]], [[4d9c\|4d9c]], [[4d9e\|4d9e]], [[4d9f\|4d9f]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dcyD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/D-cysteine_desulfhydrase D-cysteine desulfhydrase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.15 4.4.1.15] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/D-cysteine_desulfhydrase D-cysteine desulfhydrase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.15 4.4.1.15] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d8u OCA], [http://pdbe.org/4d8u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4d8u RCSB], [http://www.ebi.ac.uk/pdbsum/4d8u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4d8u ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d8u OCA], [http://pdbe.org/4d8u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4d8u RCSB], [http://www.ebi.ac.uk/pdbsum/4d8u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4d8u ProSAT]</span></td></tr>
Line 26:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus typhimurium loeffler 1892]]
	[[Category: D-cysteine desulfhydrase]]		[[Category: D-cysteine desulfhydrase]]
	[[Category: Bharath, S R]]		[[Category: Bharath, S R]]

OCA at 09:55, 11 August 2016

2016-08-11T09:55:33Z

←Older revision		Revision as of 09:55, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of D-Cysteine desulfhydrase from Salmonella typhimurium at 3.3 A in monoclinic space group with 8 subunits in the asymmetric unit==		==Crystal structure of D-Cysteine desulfhydrase from Salmonella typhimurium at 3.3 A in monoclinic space group with 8 subunits in the asymmetric unit==
	<StructureSection load='4d8u' size='340' side='right' caption='[[4d8u]], [[Resolution\|resolution]] 3.30Å' scene=''>		<StructureSection load='4d8u' size='340' side='right' caption='[[4d8u]], [[Resolution\|resolution]] 3.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4d8u]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar~~ typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D8U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D8U FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4d8u]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D8U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D8U FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=IT1:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>IT1</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=IT1:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>IT1</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d8t\|4d8t]], [[4d8w\|4d8w]], [[4d92\|4d92]], [[4d96\|4d96]], [[4d97\|4d97]], [[4d99\|4d99]], [[4d9b\|4d9b]], [[4d9c\|4d9c]], [[4d9e\|4d9e]], [[4d9f\|4d9f]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d8t\|4d8t]], [[4d8w\|4d8w]], [[4d92\|4d92]], [[4d96\|4d96]], [[4d97\|4d97]], [[4d99\|4d99]], [[4d9b\|4d9b]], [[4d9c\|4d9c]], [[4d9e\|4d9e]], [[4d9f\|4d9f]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dcyD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 ~~Salmonella enterica subsp. enterica serovar Typhimurium~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dcyD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/D-cysteine_desulfhydrase D-cysteine desulfhydrase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.15 4.4.1.15] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/D-cysteine_desulfhydrase D-cysteine desulfhydrase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.15 4.4.1.15] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d8u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d8u RCSB], [http://www.ebi.ac.uk/pdbsum/4d8u PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d8u OCA], [http://pdbe.org/4d8u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4d8u RCSB], [http://www.ebi.ac.uk/pdbsum/4d8u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4d8u ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DCYD_SALTY DCYD_SALTY]] Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine.[HAMAP-Rule:MF_01045]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 21:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4d8u" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacillus typhimurium loeffler 1892]]
	[[Category: D-cysteine desulfhydrase]]		[[Category: D-cysteine desulfhydrase]]
-	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
	[[Category: Bharath, S R]]		[[Category: Bharath, S R]]
	[[Category: Murthy, M R.N]]		[[Category: Murthy, M R.N]]

OCA at 13:40, 4 January 2015

2015-01-04T13:40:28Z

←Older revision		Revision as of 13:40, 4 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4d8u]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D8U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D8U FirstGlance]. <br>		<table><tr><td colspan='2'>[[4d8u]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D8U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D8U FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=IT1:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>IT1</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=IT1:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>IT1</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d8t\|4d8t]], [[4d8w\|4d8w]], [[4d92\|4d92]], [[4d96\|4d96]], [[4d97\|4d97]], [[4d99\|4d99]], [[4d9b\|4d9b]], [[4d9c\|4d9c]], [[4d9e\|4d9e]], [[4d9f\|4d9f]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d8t\|4d8t]], [[4d8w\|4d8w]], [[4d92\|4d92]], [[4d96\|4d96]], [[4d97\|4d97]], [[4d99\|4d99]], [[4d9b\|4d9b]], [[4d9c\|4d9c]], [[4d9e\|4d9e]], [[4d9f\|4d9f]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dcyD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 Salmonella enterica subsp. enterica serovar Typhimurium])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dcyD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 Salmonella enterica subsp. enterica serovar Typhimurium])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/D-cysteine_desulfhydrase D-cysteine desulfhydrase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.15 4.4.1.15] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/D-cysteine_desulfhydrase D-cysteine desulfhydrase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.15 4.4.1.15] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d8u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d8u RCSB], [http://www.ebi.ac.uk/pdbsum/4d8u PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d8u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d8u RCSB], [http://www.ebi.ac.uk/pdbsum/4d8u PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 16:		Line 16:
	Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase.,Bharath SR, Bisht S, Harijan RK, Savithri HS, Murthy MR PLoS One. 2012;7(5):e36267. Epub 2012 May 4. PMID:22574144<ref>PMID:22574144</ref>		Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase.,Bharath SR, Bisht S, Harijan RK, Savithri HS, Murthy MR PLoS One. 2012;7(5):e36267. Epub 2012 May 4. PMID:22574144<ref>PMID:22574144</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 24:		Line 24:
	[[Category: D-cysteine desulfhydrase]]		[[Category: D-cysteine desulfhydrase]]
	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]		[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
-	[[Category: Bharath, S R.]]	+	[[Category: Bharath, S R]]
-	[[Category: Murthy, M R.N.]]	+	[[Category: Murthy, M R.N]]
-	[[Category: Rajesh, K H.]]	+	[[Category: Rajesh, K H]]
-	[[Category: Savithri, H S.]]	+	[[Category: Savithri, H S]]
-	[[Category: Shveta, B.]]	+	[[Category: Shveta, B]]
	[[Category: Fold type ii plp-dependent enzyme]]		[[Category: Fold type ii plp-dependent enzyme]]
	[[Category: Lyase]]		[[Category: Lyase]]
	[[Category: Tryptophan synthase beta subunit-like plp-dependent enzymes superfamily]]		[[Category: Tryptophan synthase beta subunit-like plp-dependent enzymes superfamily]]

OCA at 07:21, 5 June 2014

2014-06-05T07:21:15Z

←Older revision		Revision as of 07:21, 5 June 2014
Line 1:		Line 1:
-	[[~~Image:~~4d8u.~~jpg~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of D-Cysteine desulfhydrase from Salmonella typhimurium at 3.3 A in monoclinic space group with 8 subunits in the asymmetric unit==
		+	<StructureSection load='4d8u' size='340' side='right' caption='[[4d8u]], [[Resolution\|resolution]] 3.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4d8u]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D8U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D8U FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=IT1:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>IT1</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4d8t\|4d8t]], [[4d8w\|4d8w]], [[4d92\|4d92]], [[4d96\|4d96]], [[4d97\|4d97]], [[4d99\|4d99]], [[4d9b\|4d9b]], [[4d9c\|4d9c]], [[4d9e\|4d9e]], [[4d9f\|4d9f]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dcyD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 Salmonella enterica subsp. enterica serovar Typhimurium])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/D-cysteine_desulfhydrase D-cysteine desulfhydrase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.15 4.4.1.15] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d8u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d8u RCSB], [http://www.ebi.ac.uk/pdbsum/4d8u PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Salmonella typhimurium DCyD (StDCyD) is a fold type II pyridoxal 5' phosphate (PLP)-dependent enzyme that catalyzes the degradation of D-Cys to H(2)S and pyruvate. It also efficiently degrades beta-chloro-D-alanine (betaCDA). D-Ser is a poor substrate while the enzyme is inactive with respect to L-Ser and 1-amino-1-carboxy cyclopropane (ACC). Here, we report the X-ray crystal structures of StDCyD and of crystals obtained in the presence of D-Cys, betaCDA, ACC, D-Ser, L-Ser, D-cycloserine (DCS) and L-cycloserine (LCS) at resolutions ranging from 1.7 to 2.6 A. The polypeptide fold of StDCyD consisting of a small domain (residues 48-161) and a large domain (residues 1-47 and 162-328) resembles other fold type II PLP dependent enzymes. The structures obtained in the presence of D-Cys and betaCDA show the product, pyruvate, bound at a site 4.0-6.0 A away from the active site. ACC forms an external aldimine complex while D- and L-Ser bind non-covalently suggesting that the reaction with these ligands is arrested at Calpha proton abstraction and transimination steps, respectively. In the active site of StDCyD cocrystallized with DCS or LCS, electron density for a pyridoxamine phosphate (PMP) was observed. Crystals soaked in cocktail containing these ligands show density for PLP-cycloserine. Spectroscopic observations also suggest formation of PMP by the hydrolysis of cycloserines. Mutational studies suggest that Ser78 and Gln77 are key determinants of enzyme specificity and the phenolate of Tyr287 is responsible for Calpha proton abstraction from D-Cys. Based on these studies, a probable mechanism for the degradation of D-Cys by StDCyD is proposed.

-	<!--	+	Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase.,Bharath SR, Bisht S, Harijan RK, Savithri HS, Murthy MR PLoS One. 2012;7(5):e36267. Epub 2012 May 4. PMID:22574144<ref>PMID:22574144</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_4d8u"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_4d8u\| PDB=4d8u \| SCENE= }}~~	+

-	~~===Crystal structure~~ of ~~D-Cysteine desulfhydrase from Salmonella typhimurium at 3.3 A in monoclinic space group with 8 subunits in~~ the ~~asymmetric unit===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_22574144}}, adds the Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 22574144 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_22574144}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[4d8u]] is a 8 chain structure with sequence from [http:~~//en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D8U OCA].	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022574144<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: D-cysteine desulfhydrase]]		[[Category: D-cysteine desulfhydrase]]
	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]		[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]

OCA at 05:53, 30 May 2012

2012-05-30T05:53:40Z

←Older revision		Revision as of 05:53, 30 May 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4d8u.jpg\|left\|200px]]

-	The ~~entry 4d8u~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_4d8u", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_4d8u\| PDB=4d8u \| SCENE= }}

-	~~Authors: Bharath, S.R., Shveta, B., Rajesh, K.H., Savithri, H.S., Murthy, M.R.N~~.	+	===Crystal structure of D-Cysteine desulfhydrase from Salmonella typhimurium at 3.3 A in monoclinic space group with 8 subunits in the asymmetric unit===

-	~~Description~~: ~~Crystal~~ structure of D-~~Cysteine~~ desulfhydrase ~~from~~ Salmonella typhimurium ~~at 3~~.~~3 A in monoclinic space group with 8 subunits in the asymmetric unit~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22574144}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22574144 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22574144}}
		+
		+	==About this Structure==
		+	[[4d8u]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D8U OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022574144</ref><references group="xtra"/>
		+	[[Category: D-cysteine desulfhydrase]]
		+	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
		+	[[Category: Bharath, S R.]]
		+	[[Category: Murthy, M R.N.]]
		+	[[Category: Rajesh, K H.]]
		+	[[Category: Savithri, H S.]]
		+	[[Category: Shveta, B.]]
		+	[[Category: Fold type ii plp-dependent enzyme]]
		+	[[Category: Lyase]]
		+	[[Category: Tryptophan synthase beta subunit-like plp-dependent enzymes superfamily]]

OCA at 06:19, 15 February 2012

2012-02-15T06:19:20Z

←Older revision		Revision as of 06:19, 15 February 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4d8u is ON HOLD	+	The entry 4d8u is ON HOLD until Paper Publication

	Authors: Bharath, S.R., Shveta, B., Rajesh, K.H., Savithri, H.S., Murthy, M.R.N.		Authors: Bharath, S.R., Shveta, B., Rajesh, K.H., Savithri, H.S., Murthy, M.R.N.

	Description: Crystal structure of D-Cysteine desulfhydrase from Salmonella typhimurium at 3.3 A in monoclinic space group with 8 subunits in the asymmetric unit		Description: Crystal structure of D-Cysteine desulfhydrase from Salmonella typhimurium at 3.3 A in monoclinic space group with 8 subunits in the asymmetric unit

OCA at 06:58, 1 February 2012

2012-02-01T06:58:19Z

←Older revision		Revision as of 06:58, 1 February 2012
Line 3:		Line 3:
	The entry 4d8u is ON HOLD		The entry 4d8u is ON HOLD

-	Authors: S.R., ~~Bharath~~, ~~Bisht~~, ~~Shveta~~, K.H., ~~Rajesh~~, H.S.~~, Savithri~~, Murthy, M.R.N.	+	Authors: Bharath, S.R., Shveta, B., Rajesh, K.H., Savithri, H.S., Murthy, M.R.N.

	Description: Crystal structure of D-Cysteine desulfhydrase from Salmonella typhimurium at 3.3 A in monoclinic space group with 8 subunits in the asymmetric unit		Description: Crystal structure of D-Cysteine desulfhydrase from Salmonella typhimurium at 3.3 A in monoclinic space group with 8 subunits in the asymmetric unit