4do1 - Revision history

OCA at 13:44, 8 November 2023

2023-11-08T13:44:05Z

←Older revision		Revision as of 13:44, 8 November 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4do1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodopseudomonas_palustris_HaA2 Rhodopseudomonas palustris HaA2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DO1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DO1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4do1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodopseudomonas_palustris_HaA2 Rhodopseudomonas palustris HaA2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DO1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DO1 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANN:4-METHOXYBENZOIC+ACID'>ANN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANN:4-METHOXYBENZOIC+ACID'>ANN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4do1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4do1 OCA], [https://pdbe.org/4do1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4do1 RCSB], [https://www.ebi.ac.uk/pdbsum/4do1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4do1 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4do1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4do1 OCA], [https://pdbe.org/4do1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4do1 RCSB], [https://www.ebi.ac.uk/pdbsum/4do1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4do1 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/Q2IU02_RHOP2 Q2IU02_RHOP2]]	+	[https://www.uniprot.org/uniprot/Q2IU02_RHOP2 Q2IU02_RHOP2]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 08:31, 21 September 2022

2022-09-21T08:31:32Z

←Older revision		Revision as of 08:31, 21 September 2022
Line 1:		Line 1:

	==The crystal structures of 4-methoxybenzoate bound CYP199A4==		==The crystal structures of 4-methoxybenzoate bound CYP199A4==
-	<StructureSection load='4do1' size='340' side='right' caption='[[4do1]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='4do1' size='340' side='right'caption='[[4do1]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4do1]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Rhop2 Rhop2~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DO1 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4DO1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4do1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodopseudomonas_palustris_HaA2 Rhodopseudomonas palustris HaA2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DO1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DO1 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANN:4-METHOXYBENZOIC+ACID'>ANN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANN:4-METHOXYBENZOIC+ACID'>ANN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dnz\|4dnz]], [[4egm\|4egm]], [[4egn\|4egn]], [[4ego\|4ego]], [[4egp\|4egp]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4do1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4do1 OCA], [https://pdbe.org/4do1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4do1 RCSB], [https://www.ebi.ac.uk/pdbsum/4do1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4do1 ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RPB_3613 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=316058 RHOP2])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4do1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4do1 OCA], [~~http~~://pdbe.org/4do1 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4do1 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4do1 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4do1 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/Q2IU02_RHOP2 Q2IU02_RHOP2]]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[Cytochrome P450\|Cytochrome P450]]	+	*[[Cytochrome P450 3D structures\|Cytochrome P450 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Rhop2~~]]	+	[[Category: Large Structures]]
-	[[Category: Bell~~, S G~~]]	+	[[Category: Rhodopseudomonas palustris HaA2]]
-	[[Category: Johnson~~, E O.D~~]]	+	[[Category: Bell SG]]
-	[[Category: Rao, Z]]	+	[[Category: Johnson EOD]]
-	[[Category: Tan~~, A B.H~~]]	+	[[Category: Rao Z]]
-	[[Category: Wong, L L]]	+	[[Category: Tan ABH]]
-	[[Category: Yang, W]]	+	[[Category: Wong L-L]]
-	[[Category: Zhang, A]]	+	[[Category: Yang W]]
-	[[Category: Zhou, R]]	+	[[Category: Zhang A]]
-	[[Category: Zhou, W]]	+	[[Category: Zhou R]]
-	~~[[Category: Catabolism]]~~	+	[[Category: Zhou W]]
-	~~[[Category: Cytochrome p450]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Secondary metabolites biosynthesis]]~~	+
-	~~[[Category: Transport~~]]	+

OCA at 12:58, 11 August 2016

2016-08-11T12:58:33Z

←Older revision		Revision as of 12:58, 11 August 2016
Line 1:		Line 1:
		+
	==The crystal structures of 4-methoxybenzoate bound CYP199A4==		==The crystal structures of 4-methoxybenzoate bound CYP199A4==
	<StructureSection load='4do1' size='340' side='right' caption='[[4do1]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4do1' size='340' side='right' caption='[[4do1]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4do1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Rhodopseudomonas_palustris Rhodopseudomonas palustris~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DO1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DO1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4do1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhop2 Rhop2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DO1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DO1 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANN:4-METHOXYBENZOIC+ACID'>ANN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANN:4-METHOXYBENZOIC+ACID'>ANN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dnz\|4dnz]], [[4egm\|4egm]], [[4egn\|4egn]], [[4ego\|4ego]], [[4egp\|4egp]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dnz\|4dnz]], [[4egm\|4egm]], [[4egn\|4egn]], [[4ego\|4ego]], [[4egp\|4egp]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RPB_3613 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~1076 Rhodopseudomonas palustris~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RPB_3613 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=316058 RHOP2])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4do1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4do1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4do1 RCSB], [http://www.ebi.ac.uk/pdbsum/4do1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4do1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4do1 OCA], [http://pdbe.org/4do1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4do1 RCSB], [http://www.ebi.ac.uk/pdbsum/4do1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4do1 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4do1" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 23:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Rhodopseudomonas palustris~~]]	+	[[Category: Rhop2]]
	[[Category: Bell, S G]]		[[Category: Bell, S G]]
	[[Category: Johnson, E O.D]]		[[Category: Johnson, E O.D]]

OCA at 13:05, 4 January 2015

2015-01-04T13:05:33Z

←Older revision		Revision as of 13:05, 4 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4do1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodopseudomonas_palustris Rhodopseudomonas palustris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DO1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DO1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4do1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodopseudomonas_palustris Rhodopseudomonas palustris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DO1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DO1 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANN:4-METHOXYBENZOIC+ACID'>ANN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANN:4-METHOXYBENZOIC+ACID'>ANN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dnz\|4dnz]], [[4egm\|4egm]], [[4egn\|4egn]], [[4ego\|4ego]], [[4egp\|4egp]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dnz\|4dnz]], [[4egm\|4egm]], [[4egn\|4egn]], [[4ego\|4ego]], [[4egp\|4egp]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RPB_3613 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1076 Rhodopseudomonas palustris])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RPB_3613 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1076 Rhodopseudomonas palustris])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4do1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4do1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4do1 RCSB], [http://www.ebi.ac.uk/pdbsum/4do1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4do1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4do1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4do1 RCSB], [http://www.ebi.ac.uk/pdbsum/4do1 PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Rhodopseudomonas palustris]]		[[Category: Rhodopseudomonas palustris]]
-	[[Category: Bell, S G.]]	+	[[Category: Bell, S G]]
-	[[Category: Johnson, E O.D.]]	+	[[Category: Johnson, E O.D]]
-	[[Category: Rao, Z.]]	+	[[Category: Rao, Z]]
-	[[Category: Tan, A B.H.]]	+	[[Category: Tan, A B.H]]
-	[[Category: Wong, L L.]]	+	[[Category: Wong, L L]]
-	[[Category: Yang, W.]]	+	[[Category: Yang, W]]
-	[[Category: Zhang, A.]]	+	[[Category: Zhang, A]]
-	[[Category: Zhou, R.]]	+	[[Category: Zhou, R]]
-	[[Category: Zhou, W.]]	+	[[Category: Zhou, W]]
	[[Category: Catabolism]]		[[Category: Catabolism]]
	[[Category: Cytochrome p450]]		[[Category: Cytochrome p450]]

OCA at 09:13, 11 June 2014

2014-06-11T09:13:37Z

←Older revision		Revision as of 09:13, 11 June 2014
Line 1:		Line 1:
-	[[~~Image:~~4do1.~~jpg~~\|~~left~~\|~~200px~~]]	+	==The crystal structures of 4-methoxybenzoate bound CYP199A4==
		+	<StructureSection load='4do1' size='340' side='right' caption='[[4do1]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4do1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodopseudomonas_palustris Rhodopseudomonas palustris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DO1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DO1 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANN:4-METHOXYBENZOIC+ACID'>ANN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dnz\|4dnz]], [[4egm\|4egm]], [[4egn\|4egn]], [[4ego\|4ego]], [[4egp\|4egp]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RPB_3613 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1076 Rhodopseudomonas palustris])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4do1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4do1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4do1 RCSB], [http://www.ebi.ac.uk/pdbsum/4do1 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The crystal structures of the 4-methoxybenzoate bound forms of cytochrome P450 enzymes CYP199A2 and CYP199A4 from the Rhodopseudomonas palustris strains CGA009 and HaA2 have been solved. The structures of these two enzymes, which share 86% sequence identity, are very similar though some differences are found on the proximal surface. In these structures the enzymes have a closed conformation, in contrast to the substrate-free form of CYP199A2 where an obvious substrate access channel is observed. The switch from an open to a closed conformation arises from pronounced residue side-chain movements and alterations of ion pair and hydrogen bonding interactions at the entrance of the access channel. A chloride ion bound just inside the protein surface caps the entrance to the active site and protects the substrate and the heme from the external solvent. In both structures the substrate is held in place via hydrophobic and hydrogen bond interactions. The methoxy group is located over the heme iron, accounting for the high activity and selectivity of these enzymes for oxidative demethylation of the substrate. Mutagenesis studies on CYP199A4 highlight the involvement of hydrophobic (Phe185) and hydrophilic (Arg92, Ser95 and Arg243) amino acid residues in the binding of para-substituted benzoates by these enzymes.

-	~~{{STRUCTURE_4do1\| PDB=4do1 \| SCENE= }}~~	+	The crystal structures of 4-methoxybenzoate bound CYP199A2 and CYP199A4: structural changes on substrate binding and the identification of an anion binding site.,Bell SG, Yang W, Tan AB, Zhou R, Johnson EO, Zhang A, Zhou W, Rao Z, Wong LL Dalton Trans. 2012 Jul 28;41(28):8703-14. Epub 2012 Jun 13. PMID:22695988<ref>PMID:22695988</ref>

-	~~===The crystal structures~~ of ~~4-methoxybenzoate bound CYP199A4===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_22695988}}~~	+	==See Also==
-		+	*[[Cytochrome P450\|Cytochrome P450]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~4do1~~]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodopseudomonas_palustris Rhodopseudomonas palustris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DO1 OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:022695988<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Rhodopseudomonas palustris]]		[[Category: Rhodopseudomonas palustris]]
	[[Category: Bell, S G.]]		[[Category: Bell, S G.]]

OCA at 05:44, 15 August 2012

2012-08-15T05:44:32Z

←Older revision		Revision as of 05:44, 15 August 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4do1.jpg\|left\|200px]]

-	~~The entry~~ 4do1 ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_4do1\| PDB=4do1 \| SCENE= }}

-	~~Authors: Zhou, W., Bell, S.G., Yang, W., Tan, A.B.H., Zhou, R., Johnson, E.O.D., Zhang, A., Rao, Z., Wong, L.~~-L.	+	===The crystal structures of 4-methoxybenzoate bound CYP199A4===

-	~~Description: The crystal structures of~~ 4-~~methoxybenzoate bound CYP199A4~~	+	{{ABSTRACT_PUBMED_22695988}}
		+
		+	==About this Structure==
		+	[[4do1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodopseudomonas_palustris Rhodopseudomonas palustris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DO1 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022695988</ref><references group="xtra"/>
		+	[[Category: Rhodopseudomonas palustris]]
		+	[[Category: Bell, S G.]]
		+	[[Category: Johnson, E O.D.]]
		+	[[Category: Rao, Z.]]
		+	[[Category: Tan, A B.H.]]
		+	[[Category: Wong, L L.]]
		+	[[Category: Yang, W.]]
		+	[[Category: Zhang, A.]]
		+	[[Category: Zhou, R.]]
		+	[[Category: Zhou, W.]]
		+	[[Category: Catabolism]]
		+	[[Category: Cytochrome p450]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Secondary metabolites biosynthesis]]
		+	[[Category: Transport]]

OCA at 06:36, 11 April 2012

2012-04-11T06:36:33Z

←Older revision		Revision as of 06:36, 11 April 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4do1 is ON HOLD	+	The entry 4do1 is ON HOLD until Paper Publication

	Authors: Zhou, W., Bell, S.G., Yang, W., Tan, A.B.H., Zhou, R., Johnson, E.O.D., Zhang, A., Rao, Z., Wong, L.-L.		Authors: Zhou, W., Bell, S.G., Yang, W., Tan, A.B.H., Zhou, R., Johnson, E.O.D., Zhang, A., Rao, Z., Wong, L.-L.

	Description: The crystal structures of 4-methoxybenzoate bound CYP199A4		Description: The crystal structures of 4-methoxybenzoate bound CYP199A4

OCA at 07:30, 22 February 2012

2012-02-22T07:30:37Z

←Older revision		Revision as of 07:30, 22 February 2012
Line 3:		Line 3:
	The entry 4do1 is ON HOLD		The entry 4do1 is ON HOLD

-	Authors: Zhou, W. , Bell, S. G. , Yang, W. , Tan, A. B. H. , Zhou, R , Johnson, E. O. D. , Zhang, A , Rao, Z , Wong, L. -L.	+	Authors: Zhou, W., Bell, S.G., Yang, W., Tan, A.B.H., Zhou, R., Johnson, E.O.D., Zhang, A., Rao, Z., Wong, L.-L.

	Description: The crystal structures of 4-methoxybenzoate bound CYP199A4		Description: The crystal structures of 4-methoxybenzoate bound CYP199A4

OCA: Protected "4do1" [edit=sysop:move=sysop]

2012-02-15T06:26:13Z

Protected "4do1" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:26, 15 February 2012

OCA: New page: '''Unreleased structure''' The entry 4do1 is ON HOLD Authors: Zhou, W. , Bell, S. G. , Yang, W. , Tan, A. B. H. , Zhou, R , Johnson, E. O. D. , Zhang, A , Rao, Z , Wong, L. -L. Descrip...

2012-02-15T06:26:12Z

New page: '''Unreleased structure''' The entry 4do1 is ON HOLD Authors: Zhou, W. , Bell, S. G. , Yang, W. , Tan, A. B. H. , Zhou, R , Johnson, E. O. D. , Zhang, A , Rao, Z , Wong, L. -L. Descrip...

New page

'''Unreleased structure'''

The entry 4do1 is ON HOLD

Authors: Zhou, W. , Bell, S. G. , Yang, W. , Tan, A. B. H. , Zhou, R , Johnson, E. O. D. , Zhang, A , Rao, Z , Wong, L. -L.

Description: The crystal structures of 4-methoxybenzoate bound CYP199A4