4drs - Revision history

OCA at 14:43, 14 March 2024

2024-03-14T14:43:17Z

←Older revision		Revision as of 14:43, 14 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4drs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DRS FirstGlance]. <br>		<table><tr><td colspan='2'>[[4drs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DRS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4drs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4drs OCA], [https://pdbe.org/4drs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4drs RCSB], [https://www.ebi.ac.uk/pdbsum/4drs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4drs ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4drs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4drs OCA], [https://pdbe.org/4drs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4drs RCSB], [https://www.ebi.ac.uk/pdbsum/4drs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4drs ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/Q5CSM7_CRYPI Q5CSM7_CRYPI]]	+	[https://www.uniprot.org/uniprot/Q5CSM7_CRYPI Q5CSM7_CRYPI]
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	Pyruvate kinase plays a critical role in cellular metabolism of glucose by serving as a major regulator of glycolysis. This tetrameric enzyme is allosterically regulated by different effector molecules, mainly phosphosugars. In response to binding of effector molecules and substrates, significant structural changes have been identified in various pyruvate kinase structures. Pyruvate kinase of Cryptosporidium parvum is exceptional among known enzymes of protozoan origin in that it exhibits no allosteric property in the presence of commonly known effector molecules. The crystal structure of pyruvate kinase from C. parvum has been solved by molecular replacement techniques and refined to 2.5 A resolution. In the active site a glycerol molecule is located near the gamma-phosphate site of ATP, and the protein structure displays a partially closed active site. However, unlike other structures where the active site is closed, the alpha6' helix in C. parvum pyruvate kinase unwinds and assumes an extended conformation. In the crystal structure a sulfate ion is found at a site that is occupied by a phosphate of the effector molecule in many pyruvate kinase structures. A new feature of the C. parvum pyruvate kinase structure is the presence of a disulfide bond cross-linking the two monomers in the asymmetric unit. The disulfide bond is formed between cysteine residue 26 in the short N-helix of one monomer with cysteine residue 312 in a long helix (residues 303-320) of the second monomer at the interface of these monomers. Both cysteine residues are unique to C. parvum, and the disulfide bond remained intact in a reduced environment. However, the significance of this bond, if any, remains unknown at this time.	+
-		+
-	Crystal structure of Cryptosporidium parvum pyruvate kinase.,Cook WJ, Senkovich O, Aleem K, Chattopadhyay D PLoS One. 2012;7(10):e46875. doi: 10.1371/journal.pone.0046875. Epub 2012 Oct 9. PMID:23056503<ref>PMID:23056503</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 4drs" style="background-color:#fffaf0;"></div>~~	+

	==See Also==		==See Also==
	*[[Pyruvate kinase 3D structures\|Pyruvate kinase 3D structures]]		*[[Pyruvate kinase 3D structures\|Pyruvate kinase 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 08:35, 21 September 2022

2022-09-21T08:35:45Z

←Older revision		Revision as of 08:35, 21 September 2022
Line 3:		Line 3:
	<StructureSection load='4drs' size='340' side='right'caption='[[4drs]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='4drs' size='340' side='right'caption='[[4drs]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4drs]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Crypi Crypi~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4DRS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4drs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DRS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cgd1_2040 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353152 CRYPI])</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4drs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4drs OCA], [https://pdbe.org/4drs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4drs RCSB], [https://www.ebi.ac.uk/pdbsum/4drs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4drs ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4drs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4drs OCA], [~~http~~://pdbe.org/4drs PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4drs RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4drs PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4drs ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/Q5CSM7_CRYPI Q5CSM7_CRYPI]]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[Pyruvate ~~Kinase~~\|Pyruvate ~~Kinase~~]]	+	*[[Pyruvate kinase 3D structures\|Pyruvate kinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Crypi~~]]	+	[[Category: Cryptosporidium parvum Iowa II]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Pyruvate kinase]]~~	+	[[Category: Chattopadhyay D]]
-	[[Category: Chattopadhyay, D]]	+	[[Category: Cook WJ]]
-	[[Category: Cook~~, W J]]~~	+
-	~~[[Category: Allosteric enzyme]]~~	+
-	~~[[Category: Cryptosporidium]]~~	+
-	~~[[Category: Glycolysis]]~~	+
-	~~[[Category: Kinase]]~~	+
-	~~[[Category: Pyruvate]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 11:50, 17 July 2019

2019-07-17T11:50:59Z

←Older revision		Revision as of 11:50, 17 July 2019
Line 1:		Line 1:

	==Crystal structure of Cryptosporidium parvum pyruvate kinase==		==Crystal structure of Cryptosporidium parvum pyruvate kinase==
-	<StructureSection load='4drs' size='340' side='right' caption='[[4drs]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='4drs' size='340' side='right'caption='[[4drs]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4drs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Crypi Crypi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DRS FirstGlance]. <br>		<table><tr><td colspan='2'>[[4drs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Crypi Crypi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DRS FirstGlance]. <br>
Line 26:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Crypi]]		[[Category: Crypi]]
		+	[[Category: Large Structures]]
	[[Category: Pyruvate kinase]]		[[Category: Pyruvate kinase]]
	[[Category: Chattopadhyay, D]]		[[Category: Chattopadhyay, D]]

OCA at 02:52, 11 December 2016

2016-12-11T02:52:08Z

←Older revision		Revision as of 02:52, 11 December 2016
Line 1:		Line 1:
		+
	==Crystal structure of Cryptosporidium parvum pyruvate kinase==		==Crystal structure of Cryptosporidium parvum pyruvate kinase==
	<StructureSection load='4drs' size='340' side='right' caption='[[4drs]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='4drs' size='340' side='right' caption='[[4drs]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4drs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Cryptosporidium_parvum_iowa_ii Cryptosporidium parvum iowa ii~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DRS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4drs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Crypi Crypi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DRS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cgd1_2040 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353152 ~~Cryptosporidium parvum Iowa II~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cgd1_2040 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353152 CRYPI])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4drs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4drs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4drs RCSB], [http://www.ebi.ac.uk/pdbsum/4drs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4drs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4drs OCA], [http://pdbe.org/4drs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4drs RCSB], [http://www.ebi.ac.uk/pdbsum/4drs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4drs ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4drs" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 23:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Cryptosporidium parvum iowa ii~~]]	+	[[Category: Crypi]]
	[[Category: Pyruvate kinase]]		[[Category: Pyruvate kinase]]
	[[Category: Chattopadhyay, D]]		[[Category: Chattopadhyay, D]]

OCA at 16:57, 9 December 2014

2014-12-09T16:57:35Z

←Older revision		Revision as of 16:57, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~4drs.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of Cryptosporidium parvum pyruvate kinase==
		+	<StructureSection load='4drs' size='340' side='right' caption='[[4drs]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4drs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryptosporidium_parvum_iowa_ii Cryptosporidium parvum iowa ii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DRS FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cgd1_2040 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353152 Cryptosporidium parvum Iowa II])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4drs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4drs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4drs RCSB], [http://www.ebi.ac.uk/pdbsum/4drs PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Pyruvate kinase plays a critical role in cellular metabolism of glucose by serving as a major regulator of glycolysis. This tetrameric enzyme is allosterically regulated by different effector molecules, mainly phosphosugars. In response to binding of effector molecules and substrates, significant structural changes have been identified in various pyruvate kinase structures. Pyruvate kinase of Cryptosporidium parvum is exceptional among known enzymes of protozoan origin in that it exhibits no allosteric property in the presence of commonly known effector molecules. The crystal structure of pyruvate kinase from C. parvum has been solved by molecular replacement techniques and refined to 2.5 A resolution. In the active site a glycerol molecule is located near the gamma-phosphate site of ATP, and the protein structure displays a partially closed active site. However, unlike other structures where the active site is closed, the alpha6' helix in C. parvum pyruvate kinase unwinds and assumes an extended conformation. In the crystal structure a sulfate ion is found at a site that is occupied by a phosphate of the effector molecule in many pyruvate kinase structures. A new feature of the C. parvum pyruvate kinase structure is the presence of a disulfide bond cross-linking the two monomers in the asymmetric unit. The disulfide bond is formed between cysteine residue 26 in the short N-helix of one monomer with cysteine residue 312 in a long helix (residues 303-320) of the second monomer at the interface of these monomers. Both cysteine residues are unique to C. parvum, and the disulfide bond remained intact in a reduced environment. However, the significance of this bond, if any, remains unknown at this time.

-	~~{{STRUCTURE_4drs\| PDB=4drs \| SCENE= }}~~	+	Crystal structure of Cryptosporidium parvum pyruvate kinase.,Cook WJ, Senkovich O, Aleem K, Chattopadhyay D PLoS One. 2012;7(10):e46875. doi: 10.1371/journal.pone.0046875. Epub 2012 Oct 9. PMID:23056503<ref>PMID:23056503</ref>

-	~~===Crystal structure~~ of ~~Cryptosporidium parvum pyruvate kinase===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_23056503}}~~	+	==See Also==
-		+	*[[Pyruvate Kinase\|Pyruvate Kinase]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~4drs~~]] ~~is a 2 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Cryptosporidium_parvum_iowa_ii Cryptosporidium parvum iowa ii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRS OCA].~~	+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Cryptosporidium parvum iowa ii]]		[[Category: Cryptosporidium parvum iowa ii]]
	[[Category: Pyruvate kinase]]		[[Category: Pyruvate kinase]]
-	[[Category: Chattopadhyay, D.]]	+	[[Category: Chattopadhyay, D]]
-	[[Category: Cook, W J.]]	+	[[Category: Cook, W J]]
	[[Category: Allosteric enzyme]]		[[Category: Allosteric enzyme]]
	[[Category: Cryptosporidium]]		[[Category: Cryptosporidium]]

OCA at 11:47, 23 January 2013

2013-01-23T11:47:35Z

←Older revision		Revision as of 11:47, 23 January 2013
Line 1:		Line 1:
-	[[Image:4drs.~~jpg~~\|left\|200px]]	+	[[Image:4drs.png\|left\|200px]]

	{{STRUCTURE_4drs\| PDB=4drs \| SCENE= }}		{{STRUCTURE_4drs\| PDB=4drs \| SCENE= }}
Line 5:		Line 5:
	===Crystal structure of Cryptosporidium parvum pyruvate kinase===		===Crystal structure of Cryptosporidium parvum pyruvate kinase===

		+	{{ABSTRACT_PUBMED_23056503}}

	==About this Structure==		==About this Structure==

OCA at 07:11, 17 October 2012

2012-10-17T07:11:05Z

←Older revision		Revision as of 07:11, 17 October 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4drs.jpg\|left\|200px]]

-	~~The entry~~ 4drs ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_4drs\| PDB=4drs \| SCENE= }}

-	~~Authors: Cook, W.J., Chattopadhyay, D.~~	+	===Crystal structure of Cryptosporidium parvum pyruvate kinase===

-	~~Description: Crystal~~ structure of Cryptosporidium parvum ~~pyruvate~~ kinase	+
		+	==About this Structure==
		+	[[4drs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryptosporidium_parvum_iowa_ii Cryptosporidium parvum iowa ii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRS OCA].
		+	[[Category: Cryptosporidium parvum iowa ii]]
		+	[[Category: Pyruvate kinase]]
		+	[[Category: Chattopadhyay, D.]]
		+	[[Category: Cook, W J.]]
		+	[[Category: Allosteric enzyme]]
		+	[[Category: Cryptosporidium]]
		+	[[Category: Glycolysis]]
		+	[[Category: Kinase]]
		+	[[Category: Pyruvate]]
		+	[[Category: Transferase]]

OCA at 06:45, 10 October 2012

2012-10-10T06:45:54Z

←Older revision		Revision as of 06:45, 10 October 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4drs is ON HOLD	+	The entry 4drs is ON HOLD until Paper Publication

	Authors: Cook, W.J., Chattopadhyay, D.		Authors: Cook, W.J., Chattopadhyay, D.

	Description: Crystal structure of Cryptosporidium parvum pyruvate kinase		Description: Crystal structure of Cryptosporidium parvum pyruvate kinase

OCA at 05:17, 27 June 2012

2012-06-27T05:17:42Z

←Older revision		Revision as of 05:17, 27 June 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4drs is ON HOLD ~~until Paper Publication~~	+	The entry 4drs is ON HOLD

	Authors: Cook, W.J., Chattopadhyay, D.		Authors: Cook, W.J., Chattopadhyay, D.

	Description: Crystal structure of Cryptosporidium parvum pyruvate kinase		Description: Crystal structure of Cryptosporidium parvum pyruvate kinase

OCA at 05:23, 30 May 2012

2012-05-30T05:23:28Z

←Older revision		Revision as of 05:23, 30 May 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4drs is ON HOLD	+	The entry 4drs is ON HOLD until Paper Publication

	Authors: Cook, W.J., Chattopadhyay, D.		Authors: Cook, W.J., Chattopadhyay, D.

	Description: Crystal structure of Cryptosporidium parvum pyruvate kinase		Description: Crystal structure of Cryptosporidium parvum pyruvate kinase