4edn - Revision history

OCA at 07:06, 28 September 2022

2022-09-28T07:06:25Z

←Older revision		Revision as of 07:06, 28 September 2022
Line 1:		Line 1:

	==Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif==		==Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif==
-	<StructureSection load='4edn' size='340' side='right' caption='[[4edn]], [[Resolution\|resolution]] 2.90Å' scene=''>	+	<StructureSection load='4edn' size='340' side='right'caption='[[4edn]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4edn]] is a 17 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EDN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4EDN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4edn]] is a 17 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EDN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EDN FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr~~ id~~='NonStdRes'><td class~~="~~sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat~~"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene><~~/td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4edn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4edn OCA], [https://pdbe.org/4edn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4edn RCSB], [https://www.ebi.ac.uk/pdbsum/4edn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4edn ProSAT]</span></td></tr>
-	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b></td><td class="sblockDat">[[4edl\|4edl]], [[4edm\|4edm]]</td></tr>~~	+
-	~~<tr id='gene~~'>~~<td class="sblockLbl"><b>[[Gene\|Gene:]]~~</b>~~</td><td class="sblockDat">PARVB, CGI-56 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4edn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4edn OCA], [~~http~~://pdbe.org/4edn PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4edn RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4edn PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4edn ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/PARVB_HUMAN PARVB_HUMAN]] Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration.<ref>PMID:11402068</ref> <ref>PMID:15005707</ref> <ref>PMID:15284246</ref> <ref>PMID:15159419</ref> <ref>PMID:18325335</ref> ~~[[http://www.uniprot.org/uniprot/PAXI_HUMAN PAXI_HUMAN]] Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).~~	+	[[https://www.uniprot.org/uniprot/PARVB_HUMAN PARVB_HUMAN]] Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration.<ref>PMID:11402068</ref> <ref>PMID:15005707</ref> <ref>PMID:15284246</ref> <ref>PMID:15159419</ref> <ref>PMID:18325335</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 20:

	==See Also==		==See Also==
		+	*[[Parvin 3D structures\|Parvin 3D structures]]
	*[[Paxillin\|Paxillin]]		*[[Paxillin\|Paxillin]]
	== References ==		== References ==
Line 28:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: Boggon~~, T J~~]]	+	[[Category: Large Structures]]
-	[[Category: Calderwood~~, D A~~]]	+	[[Category: Boggon TJ]]
-	[[Category: Chayen~~, N E~~]]	+	[[Category: Calderwood DA]]
-	[[Category: Draheim~~, K M~~]]	+	[[Category: Chayen NE]]
-	[[Category: Li, X]]	+	[[Category: Draheim KM]]
-	[[Category: Stiegler~~, A L]]~~	+	[[Category: Li X]]
-	~~[[Category: Adaptor protein]]~~	+	[[Category: Stiegler AL]]
-	~~[[Category: Calponin homology domain]]~~	+
-	~~[[Category: Focal adhesion]]~~	+
-	~~[[Category: Integrin linked kinase]]~~	+
-	~~[[Category: Integrin signaling]]~~	+
-	~~[[Category: Ld motif]]~~	+
-	~~[[Category: Paxillin]]~~	+
-	~~[[Category: Protein-protein interaction]]~~	+
-	~~[[Category: Signaling protein-cell adhesion complex~~]]	+

OCA at 10:18, 4 August 2016

2016-08-04T10:18:25Z

←Older revision		Revision as of 10:18, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif==		==Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif==
	<StructureSection load='4edn' size='340' side='right' caption='[[4edn]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='4edn' size='340' side='right' caption='[[4edn]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4edn]] is a 17 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EDN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EDN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4edn]] is a 17 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EDN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EDN FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4edl\|4edl]], [[4edm\|4edm]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4edl\|4edl]], [[4edm\|4edm]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PARVB, CGI-56 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PARVB, CGI-56 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4edn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4edn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4edn RCSB], [http://www.ebi.ac.uk/pdbsum/4edn PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4edn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4edn OCA], [http://pdbe.org/4edn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4edn RCSB], [http://www.ebi.ac.uk/pdbsum/4edn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4edn ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4edn" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Paxillin\|Paxillin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Boggon, T J]]		[[Category: Boggon, T J]]
	[[Category: Calderwood, D A]]		[[Category: Calderwood, D A]]

OCA at 08:51, 24 December 2014

2014-12-24T08:51:01Z

←Older revision		Revision as of 08:51, 24 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4edn\| PDB=4edn \| SCENE= }}~~	+	==Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif==
-	===Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif===	+	<StructureSection load='4edn' size='340' side='right' caption='[[4edn]], [[Resolution\|resolution]] 2.90Å' scene=''>
-	~~{{ABSTRACT_PUBMED_22869380}}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4edn]] is a 17 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EDN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EDN FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4edl\|4edl]], [[4edm\|4edm]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PARVB, CGI-56 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4edn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4edn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4edn RCSB], [http://www.ebi.ac.uk/pdbsum/4edn PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/PARVB_HUMAN PARVB_HUMAN]] Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration.<ref>PMID:11402068</ref> <ref>PMID:15005707</ref> <ref>PMID:15284246</ref> <ref>PMID:15159419</ref> <ref>PMID:18325335</ref> [[http://www.uniprot.org/uniprot/PAXI_HUMAN PAXI_HUMAN]] Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).		[[http://www.uniprot.org/uniprot/PARVB_HUMAN PARVB_HUMAN]] Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration.<ref>PMID:11402068</ref> <ref>PMID:15005707</ref> <ref>PMID:15284246</ref> <ref>PMID:15159419</ref> <ref>PMID:18325335</ref> [[http://www.uniprot.org/uniprot/PAXI_HUMAN PAXI_HUMAN]] Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	beta-Parvin is a cytoplasmic adaptor protein that localizes to focal adhesions where it interacts with integrin-linked kinase and is involved in linking integrin receptors to the cytoskeleton. It has been reported that despite high sequence similarity to alpha-parvin, beta-parvin does not bind paxillin, suggesting distinct interactions and cellular functions for these two closely related parvins. Here, we reveal that beta-parvin binds directly and specifically to leucine-aspartic acid repeat (LD) motifs in paxillin via its C-terminal calponin homology (CH2) domain. We present the co-crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif to 2.9 A resolution and find that the interaction is similar to that previously observed between alpha-parvin and paxillin LD1. We also present crystal structures of unbound beta-parvin CH2 domain at 2.1 A and 2.0 A resolution that show significant conformational flexibility in the N-terminal alpha-helix, suggesting an induced fit upon paxillin binding. We find that beta-parvin has specificity for the LD1, LD2, and LD4 motifs of paxillin, with K(D) values determined to 27, 42, and 73 mum, respectively, by surface plasmon resonance. Furthermore, we show that proper localization of beta-parvin to focal adhesions requires both the paxillin and integrin-linked kinase binding sites and that paxillin is important for early targeting of beta-parvin. These studies provide the first molecular details of beta-parvin binding to paxillin and help define the requirements for beta-parvin localization to focal adhesions.

-	~~==About this Structure==~~	+	Structural Basis for Paxillin Binding and Focal Adhesion Targeting of beta-Parvin.,Stiegler AL, Draheim KM, Li X, Chayen NE, Calderwood DA, Boggon TJ J Biol Chem. 2012 Sep 21;287(39):32566-77. Epub 2012 Aug 6. PMID:22869380<ref>PMID:22869380</ref>
-	~~[[4edn]] is a 17 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=4EDN OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:022869380</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Boggon, T J.]]	+	[[Category: Boggon, T J]]
-	[[Category: Calderwood, D A.]]	+	[[Category: Calderwood, D A]]
-	[[Category: Chayen, N E.]]	+	[[Category: Chayen, N E]]
-	[[Category: Draheim, K M.]]	+	[[Category: Draheim, K M]]
-	[[Category: Li, X.]]	+	[[Category: Li, X]]
-	[[Category: Stiegler, A L.]]	+	[[Category: Stiegler, A L]]
	[[Category: Adaptor protein]]		[[Category: Adaptor protein]]
	[[Category: Calponin homology domain]]		[[Category: Calponin homology domain]]

OCA at 07:55, 19 June 2013

2013-06-19T07:55:50Z

←Older revision		Revision as of 07:55, 19 June 2013
Line 1:		Line 1:
-	[[Image:4edn.png\|left\|200px]]
-
	{{STRUCTURE_4edn\| PDB=4edn \| SCENE= }}		{{STRUCTURE_4edn\| PDB=4edn \| SCENE= }}
-
	===Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif===		===Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif===
-
	{{ABSTRACT_PUBMED_22869380}}		{{ABSTRACT_PUBMED_22869380}}
		+
		+	==Function==
		+	[[http://www.uniprot.org/uniprot/PARVB_HUMAN PARVB_HUMAN]] Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration.<ref>PMID:11402068</ref> <ref>PMID:15005707</ref> <ref>PMID:15284246</ref> <ref>PMID:15159419</ref> <ref>PMID:18325335</ref> [[http://www.uniprot.org/uniprot/PAXI_HUMAN PAXI_HUMAN]] Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).

	==About this Structure==		==About this Structure==
	[[4edn]] is a 17 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EDN OCA].		[[4edn]] is a 17 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EDN OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022869380</ref><references group="xtra"/><references/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Boggon, T J.]]		[[Category: Boggon, T J.]]

OCA at 20:30, 26 September 2012

2012-09-26T20:30:28Z

←Older revision		Revision as of 20:30, 26 September 2012
Line 1:		Line 1:
-	[[Image:4edn.~~jpg~~\|left\|200px]]	+	[[Image:4edn.png\|left\|200px]]

	{{STRUCTURE_4edn\| PDB=4edn \| SCENE= }}		{{STRUCTURE_4edn\| PDB=4edn \| SCENE= }}
Line 5:		Line 5:
	===Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif===		===Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif===

		+	{{ABSTRACT_PUBMED_22869380}}

	==About this Structure==		==About this Structure==

OCA at 05:33, 8 August 2012

2012-08-08T05:33:54Z

←Older revision		Revision as of 05:33, 8 August 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4edn.jpg\|left\|200px]]

-	~~The entry~~ 4edn ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_4edn\| PDB=4edn \| SCENE= }}

-	~~Authors: Stiegler, A.L., Draheim, K.M., Li, X., Chayen, N.E., Calderwood, D.A., Boggon, T.J.~~	+	===Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif===

-	~~Description~~: ~~Protein~~ X	+
		+	==About this Structure==
		+	[[4edn]] is a 17 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EDN OCA].
		+	[[Category: Homo sapiens]]
		+	[[Category: Boggon, T J.]]
		+	[[Category: Calderwood, D A.]]
		+	[[Category: Chayen, N E.]]
		+	[[Category: Draheim, K M.]]
		+	[[Category: Li, X.]]
		+	[[Category: Stiegler, A L.]]
		+	[[Category: Adaptor protein]]
		+	[[Category: Calponin homology domain]]
		+	[[Category: Focal adhesion]]
		+	[[Category: Integrin linked kinase]]
		+	[[Category: Integrin signaling]]
		+	[[Category: Ld motif]]
		+	[[Category: Paxillin]]
		+	[[Category: Protein-protein interaction]]
		+	[[Category: Signaling protein-cell adhesion complex]]

OCA at 06:41, 11 April 2012

2012-04-11T06:41:02Z

←Older revision		Revision as of 06:41, 11 April 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4edn is ON HOLD	+	The entry 4edn is ON HOLD until Paper Publication

-	Authors: Stiegler, A.L., Draheim, K.M., Li, X., Calderwood, D.A., Boggon, T.J.	+	Authors: Stiegler, A.L., Draheim, K.M., Li, X., Chayen, N.E., Calderwood, D.A., Boggon, T.J.

	Description: Protein X		Description: Protein X

OCA: Protected "4edn" [edit=sysop:move=sysop]

2012-04-04T05:49:33Z

Protected "4edn" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:49, 4 April 2012

OCA: New page: '''Unreleased structure''' The entry 4edn is ON HOLD Authors: Stiegler, A.L., Draheim, K.M., Li, X., Calderwood, D.A., Boggon, T.J. Description: Protein X

2012-04-04T05:49:32Z

New page: '''Unreleased structure''' The entry 4edn is ON HOLD Authors: Stiegler, A.L., Draheim, K.M., Li, X., Calderwood, D.A., Boggon, T.J. Description: Protein X

New page

'''Unreleased structure'''

The entry 4edn is ON HOLD

Authors: Stiegler, A.L., Draheim, K.M., Li, X., Calderwood, D.A., Boggon, T.J.

Description: Protein X