4eox - Revision history

OCA at 11:04, 1 March 2024

2024-03-01T11:04:33Z

←Older revision		Revision as of 11:04, 1 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4eox]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_R6 Streptococcus pneumoniae R6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EOX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EOX FirstGlance]. <br>		<table><tr><td colspan='2'>[[4eox]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_R6 Streptococcus pneumoniae R6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EOX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EOX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0S5:N-BENZOYL-1-[(2R)-3-CYCLOPENTYL-2-{[FORMYL(HYDROXY)AMINO]METHYL}PROPANOYL]-L-PROLINAMIDE'>0S5</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.783Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0S5:N-BENZOYL-1-[(2R)-3-CYCLOPENTYL-2-{[FORMYL(HYDROXY)AMINO]METHYL}PROPANOYL]-L-PROLINAMIDE'>0S5</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eox OCA], [https://pdbe.org/4eox PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eox RCSB], [https://www.ebi.ac.uk/pdbsum/4eox PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eox ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eox OCA], [https://pdbe.org/4eox PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eox RCSB], [https://www.ebi.ac.uk/pdbsum/4eox PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eox ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/DEF_STRR6 DEF_STRR6]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).	+	[https://www.uniprot.org/uniprot/DEF_STRR6 DEF_STRR6] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	A new class of PDF inhibitor with potent, broad spectrum antibacterial activity is described. Optimization of blood stability and potency provided compounds with improved pharmacokinetics that were suitable for in vivo experiments. Compound 5c, which has robust antibacterial activity, demonstrated efficacy in two respiratory tract infection models.	+
-		+
-	Acylprolinamides: A new class of peptide deformylase inhibitors with in vivo antibacterial activity.,Axten JM, Medina JR, Blackledge CW, Duquenne C, Grant SW, Bobko MA, Peng T, Miller WH, Pinckney T, Gallagher TF, Kulkarni S, Lewandowski T, Van Aller GS, Zonis R, Ward P, Campobasso N Bioorg Med Chem Lett. 2012 Jun 15;22(12):4028-32. Epub 2012 Apr 25. PMID:22579486<ref>PMID:22579486</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 4eox" style="background-color:#fffaf0;"></div>~~	+
-	~~== References ==~~	+
-	~~<references/>~~	+
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 07:21, 28 September 2022

2022-09-28T07:21:13Z

←Older revision		Revision as of 07:21, 28 September 2022
Line 1:		Line 1:

	==X-ray Structure of Polypeptide Deformylase Bound to a Acylprolinamide inhibitor==		==X-ray Structure of Polypeptide Deformylase Bound to a Acylprolinamide inhibitor==
-	<StructureSection load='4eox' size='340' side='right' caption='[[4eox]], [[Resolution\|resolution]] 1.78Å' scene=''>	+	<StructureSection load='4eox' size='340' side='right'caption='[[4eox]], [[Resolution\|resolution]] 1.78Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4eox]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Strr6 Strr6~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EOX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4EOX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4eox]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_R6 Streptococcus pneumoniae R6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EOX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EOX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0S5:N-BENZOYL-1-[(2R)-3-CYCLOPENTYL-2-{[FORMYL(HYDROXY)AMINO]METHYL}PROPANOYL]-L-PROLINAMIDE'>0S5</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0S5:N-BENZOYL-1-[(2R)-3-CYCLOPENTYL-2-{[FORMYL(HYDROXY)AMINO]METHYL}PROPANOYL]-L-PROLINAMIDE'>0S5</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">def, spr1310 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=171101 STRR6])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eox OCA], [https://pdbe.org/4eox PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eox RCSB], [https://www.ebi.ac.uk/pdbsum/4eox PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eox ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4eox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eox OCA], [~~http~~://pdbe.org/4eox PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4eox RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4eox PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4eox ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/DEF_STRR6 DEF_STRR6]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).	+	[[https://www.uniprot.org/uniprot/DEF_STRR6 DEF_STRR6]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Peptide deformylase~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Strr6~~]]	+	[[Category: Streptococcus pneumoniae R6]]
-	[[Category: Campobasso, N]]	+	[[Category: Campobasso N]]
-	[[Category: Ward, P]]	+	[[Category: Ward P]]
-	~~[[Category: Alpha-beta]]~~	+
-	~~[[Category: Hydrolase-hydrolase inhibitor complex]]~~	+
-	~~[[Category: Peptide deformylase metal ion binding~~]]	+

OCA at 06:40, 5 August 2016

2016-08-05T06:40:31Z

←Older revision		Revision as of 06:40, 5 August 2016
Line 1:		Line 1:
		+
	==X-ray Structure of Polypeptide Deformylase Bound to a Acylprolinamide inhibitor==		==X-ray Structure of Polypeptide Deformylase Bound to a Acylprolinamide inhibitor==
	<StructureSection load='4eox' size='340' side='right' caption='[[4eox]], [[Resolution\|resolution]] 1.78Å' scene=''>		<StructureSection load='4eox' size='340' side='right' caption='[[4eox]], [[Resolution\|resolution]] 1.78Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4eox]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptococcus_pneumoniae_r6 Streptococcus pneumoniae r6~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EOX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EOX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4eox]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Strr6 Strr6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EOX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EOX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0S5:N-BENZOYL-1-[(2R)-3-CYCLOPENTYL-2-{[FORMYL(HYDROXY)AMINO]METHYL}PROPANOYL]-L-PROLINAMIDE'>0S5</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0S5:N-BENZOYL-1-[(2R)-3-CYCLOPENTYL-2-{[FORMYL(HYDROXY)AMINO]METHYL}PROPANOYL]-L-PROLINAMIDE'>0S5</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">def, spr1310 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=171101 ~~Streptococcus pneumoniae R6~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">def, spr1310 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=171101 STRR6])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eox OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eox RCSB], [http://www.ebi.ac.uk/pdbsum/4eox PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eox OCA], [http://pdbe.org/4eox PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4eox RCSB], [http://www.ebi.ac.uk/pdbsum/4eox PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4eox ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4eox" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
Line 23:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Peptide deformylase]]		[[Category: Peptide deformylase]]
-	[[Category: ~~Streptococcus pneumoniae r6~~]]	+	[[Category: Strr6]]
	[[Category: Campobasso, N]]		[[Category: Campobasso, N]]
	[[Category: Ward, P]]		[[Category: Ward, P]]

OCA at 16:35, 25 December 2014

2014-12-25T16:35:44Z

←Older revision		Revision as of 16:35, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eox OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eox RCSB], [http://www.ebi.ac.uk/pdbsum/4eox PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eox OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eox RCSB], [http://www.ebi.ac.uk/pdbsum/4eox PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DEF_STRR6 DEF_STRR6]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 16:29, 9 December 2014

2014-12-09T16:29:07Z

←Older revision		Revision as of 16:29, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~4eox.~~png~~\|~~left~~\|~~200px~~]]	+	==X-ray Structure of Polypeptide Deformylase Bound to a Acylprolinamide inhibitor==
		+	<StructureSection load='4eox' size='340' side='right' caption='[[4eox]], [[Resolution\|resolution]] 1.78Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4eox]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_r6 Streptococcus pneumoniae r6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EOX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EOX FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0S5:N-BENZOYL-1-[(2R)-3-CYCLOPENTYL-2-{[FORMYL(HYDROXY)AMINO]METHYL}PROPANOYL]-L-PROLINAMIDE'>0S5</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">def, spr1310 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=171101 Streptococcus pneumoniae R6])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eox OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eox RCSB], [http://www.ebi.ac.uk/pdbsum/4eox PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	A new class of PDF inhibitor with potent, broad spectrum antibacterial activity is described. Optimization of blood stability and potency provided compounds with improved pharmacokinetics that were suitable for in vivo experiments. Compound 5c, which has robust antibacterial activity, demonstrated efficacy in two respiratory tract infection models.

-	~~{{STRUCTURE_4eox\| PDB=4eox \| SCENE= }}~~	+	Acylprolinamides: A new class of peptide deformylase inhibitors with in vivo antibacterial activity.,Axten JM, Medina JR, Blackledge CW, Duquenne C, Grant SW, Bobko MA, Peng T, Miller WH, Pinckney T, Gallagher TF, Kulkarni S, Lewandowski T, Van Aller GS, Zonis R, Ward P, Campobasso N Bioorg Med Chem Lett. 2012 Jun 15;22(12):4028-32. Epub 2012 Apr 25. PMID:22579486<ref>PMID:22579486</ref>

-	~~===X-ray Structure~~ of ~~Polypeptide Deformylase Bound to a Acylprolinamide inhibitor===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22579486}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[4eox]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Streptococcus_pneumoniae_r6 Streptococcus pneumoniae r6]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4EOX OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022579486<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Peptide deformylase]]		[[Category: Peptide deformylase]]
	[[Category: Streptococcus pneumoniae r6]]		[[Category: Streptococcus pneumoniae r6]]
-	[[Category: Campobasso, N.]]	+	[[Category: Campobasso, N]]
-	[[Category: Ward, P.]]	+	[[Category: Ward, P]]
	[[Category: Alpha-beta]]		[[Category: Alpha-beta]]
	[[Category: Hydrolase-hydrolase inhibitor complex]]		[[Category: Hydrolase-hydrolase inhibitor complex]]
	[[Category: Peptide deformylase metal ion binding]]		[[Category: Peptide deformylase metal ion binding]]

OCA at 07:07, 2 January 2013

2013-01-02T07:07:23Z

←Older revision		Revision as of 07:07, 2 January 2013
Line 1:		Line 1:
-	[[Image:4eox.~~jpg~~\|left\|200px]]	+	[[Image:4eox.png\|left\|200px]]

-	<!--
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-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
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-	or leave the SCENE parameter empty for the default display.
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	{{STRUCTURE_4eox\| PDB=4eox \| SCENE= }}		{{STRUCTURE_4eox\| PDB=4eox \| SCENE= }}

	===X-ray Structure of Polypeptide Deformylase Bound to a Acylprolinamide inhibitor===		===X-ray Structure of Polypeptide Deformylase Bound to a Acylprolinamide inhibitor===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_22579486}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 22579486 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_22579486}}		{{ABSTRACT_PUBMED_22579486}}

	==About this Structure==		==About this Structure==
-	[[4eox]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptococcus_pneumoniae~~ Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EOX OCA].	+	[[4eox]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_r6 Streptococcus pneumoniae r6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EOX OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:022579486</ref><references group="xtra"/>		<ref group="xtra">PMID:022579486</ref><references group="xtra"/>
	[[Category: Peptide deformylase]]		[[Category: Peptide deformylase]]
-	[[Category: Streptococcus pneumoniae]]	+	[[Category: Streptococcus pneumoniae r6]]
	[[Category: Campobasso, N.]]		[[Category: Campobasso, N.]]
	[[Category: Ward, P.]]		[[Category: Ward, P.]]

OCA at 05:51, 30 May 2012

2012-05-30T05:51:39Z

←Older revision		Revision as of 05:51, 30 May 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4eox.jpg\|left\|200px]]

-	The ~~entry 4eox~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_4eox", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_4eox\| PDB=4eox \| SCENE= }}

-	~~Authors: Ward, P., Campobasso, N.~~	+	===X-ray Structure of Polypeptide Deformylase Bound to a Acylprolinamide inhibitor===

-	~~Description~~: X-~~ray~~ Structure ~~of Polypeptide Deformylase Bound to~~ a ~~Acylprolinamide~~ inhibitor	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22579486}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22579486 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22579486}}
		+
		+	==About this Structure==
		+	[[4eox]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EOX OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022579486</ref><references group="xtra"/>
		+	[[Category: Peptide deformylase]]
		+	[[Category: Streptococcus pneumoniae]]
		+	[[Category: Campobasso, N.]]
		+	[[Category: Ward, P.]]
		+	[[Category: Alpha-beta]]
		+	[[Category: Hydrolase-hydrolase inhibitor complex]]
		+	[[Category: Peptide deformylase metal ion binding]]

OCA: Protected "4eox" [edit=sysop:move=sysop]

2012-04-25T08:55:54Z

Protected "4eox" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:55, 25 April 2012

OCA: New page: '''Unreleased structure''' The entry 4eox is ON HOLD Authors: Ward, P., Campobasso, N. Description: X-ray Structure of Polypeptide Deformylase Bound to a Acylprolinamide inhibitor

2012-04-25T08:55:53Z

New page: '''Unreleased structure''' The entry 4eox is ON HOLD Authors: Ward, P., Campobasso, N. Description: X-ray Structure of Polypeptide Deformylase Bound to a Acylprolinamide inhibitor

New page

'''Unreleased structure'''

The entry 4eox is ON HOLD

Authors: Ward, P., Campobasso, N.

Description: X-ray Structure of Polypeptide Deformylase Bound to a Acylprolinamide inhibitor