4fhp - Revision history

OCA at 15:25, 14 March 2024

2024-03-14T15:25:00Z

←Older revision		Revision as of 15:25, 14 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4fhp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FHP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FHP FirstGlance]. <br>		<table><tr><td colspan='2'>[[4fhp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FHP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FHP FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fhp OCA], [https://pdbe.org/4fhp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fhp RCSB], [https://www.ebi.ac.uk/pdbsum/4fhp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fhp ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fhp OCA], [https://pdbe.org/4fhp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fhp RCSB], [https://www.ebi.ac.uk/pdbsum/4fhp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fhp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/CID1_SCHPO CID1_SCHPO] Involved in cell cycle arrest where in association with crb2/rhp9 and chk1 it inhibits unscheduled mitosis.		[https://www.uniprot.org/uniprot/CID1_SCHPO CID1_SCHPO] Involved in cell cycle arrest where in association with crb2/rhp9 and chk1 it inhibits unscheduled mitosis.
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Polyuridylation is emerging as a ubiquitous post-translational modification with important roles in multiple aspects of RNA metabolism. These poly (U) tails are added by poly (U) polymerases with homology to poly (A) polymerases; nevertheless, the selection for UTP over ATP remains enigmatic. We report the structures of poly (U) polymerase Cid1 from Schizoscaccharomyces pombe alone and in complex with UTP, CTP, GTP and 3'-dATP. These structures reveal that each of the 4 nt can be accommodated at the active site; however, differences exist that suggest how the polymerase selects UTP over the other nucleotides. Furthermore, we find that Cid1 shares a number of common UTP recognition features with the kinetoplastid terminal uridyltransferases. Kinetic analysis of Cid1's activity for its preferred substrates, UTP and ATP, reveal a clear preference for UTP over ATP. Ultimately, we show that a single histidine in the active site plays a pivotal role for poly (U) activity. Notably, this residue is typically replaced by an asparagine residue in Cid1-family poly (A) polymerases. By mutating this histidine to an asparagine residue in Cid1, we diminished Cid1's activity for UTP addition and improved ATP incorporation, supporting that this residue is important for UTP selectivity.
-
-	Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity.,Lunde BM, Magler I, Meinhart A Nucleic Acids Res. 2012 Aug 9. PMID:22885303<ref>PMID:22885303</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4fhp" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Poly(A) RNA polymerase\|Poly(A) RNA polymerase]]		*[[Poly(A) RNA polymerase\|Poly(A) RNA polymerase]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 19:49, 19 October 2022

2022-10-19T19:49:31Z

←Older revision		Revision as of 19:49, 19 October 2022
Line 1:		Line 1:

	==Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - CaUTP bound==		==Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - CaUTP bound==
-	<StructureSection load='4fhp' size='340' side='right' caption='[[4fhp]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='4fhp' size='340' side='right'caption='[[4fhp]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4fhp]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Fission_yeast Fission yeast~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FHP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4FHP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4fhp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FHP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FHP FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fh3\|4fh3]], [[4fh5\|4fh5]], [[4fhv\|4fhv]], [[4fhw\|4fhw]], [[4fhx\|4fhx]], [[4fhy\|4fhy]]</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fhp OCA], [https://pdbe.org/4fhp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fhp RCSB], [https://www.ebi.ac.uk/pdbsum/4fhp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fhp ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cid1, SPAC19D5.03 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4fhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fhp OCA], [~~http~~://pdbe.org/4fhp PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4fhp RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4fhp PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4fhp ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/CID1_SCHPO CID1_SCHPO]] Involved in cell cycle arrest where in association with crb2/rhp9 and chk1 it inhibits unscheduled mitosis.	+	[https://www.uniprot.org/uniprot/CID1_SCHPO CID1_SCHPO] Involved in cell cycle arrest where in association with crb2/rhp9 and chk1 it inhibits unscheduled mitosis.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 20:

	==See Also==		==See Also==
-	*[[Poly(A) RNA polymerase ~~protein Cid1~~\|Poly(A) ~~RNA polymerase protein Cid1]]~~	+	*[[Poly(A) RNA polymerase\|Poly(A) RNA polymerase]]
-	*[[RNA polymerase\|RNA polymerase]]	+
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Fission yeast~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Lunde, B M~~]]	+	[[Category: Schizosaccharomyces pombe 972h-]]
-	[[Category: ~~Magler, I~~]]	+	[[Category: Lunde BM]]
-	[[Category: ~~Meinhart, A~~]]	+	[[Category: Magler I]]
-	[[Category: ~~Nucleotidyltransferase]]~~	+	[[Category: Meinhart A]]
-	~~[[Category: Transferase~~]]	+

OCA at 13:43, 5 August 2016

2016-08-05T13:43:36Z

←Older revision		Revision as of 13:43, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - CaUTP bound==		==Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - CaUTP bound==
	<StructureSection load='4fhp' size='340' side='right' caption='[[4fhp]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='4fhp' size='340' side='right' caption='[[4fhp]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4fhp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FHP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FHP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4fhp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Fission_yeast Fission yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FHP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FHP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fh3\|4fh3]], [[4fh5\|4fh5]], [[4fhv\|4fhv]], [[4fhw\|4fhw]], [[4fhx\|4fhx]], [[4fhy\|4fhy]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fh3\|4fh3]], [[4fh5\|4fh5]], [[4fhv\|4fhv]], [[4fhw\|4fhw]], [[4fhx\|4fhx]], [[4fhy\|4fhy]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cid1, SPAC19D5.03 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 ~~Schizosaccharomyces pombe 972h-~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cid1, SPAC19D5.03 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fhp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fhp RCSB], [http://www.ebi.ac.uk/pdbsum/4fhp PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fhp OCA], [http://pdbe.org/4fhp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fhp RCSB], [http://www.ebi.ac.uk/pdbsum/4fhp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fhp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4fhp" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
		+	*[[Poly(A) RNA polymerase protein Cid1\|Poly(A) RNA polymerase protein Cid1]]
	*[[RNA polymerase\|RNA polymerase]]		*[[RNA polymerase\|RNA polymerase]]
	== References ==		== References ==
Line 25:		Line 28:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Schizosaccharomyces pombe 972h-~~]]	+	[[Category: Fission yeast]]
	[[Category: Lunde, B M]]		[[Category: Lunde, B M]]
	[[Category: Magler, I]]		[[Category: Magler, I]]

OCA at 19:17, 25 December 2014

2014-12-25T19:17:25Z

←Older revision		Revision as of 19:17, 25 December 2014
Line 1:		Line 1:
-	[[~~Image:~~4fhp.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - CaUTP bound==
		+	<StructureSection load='4fhp' size='340' side='right' caption='[[4fhp]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4fhp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FHP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FHP FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fh3\|4fh3]], [[4fh5\|4fh5]], [[4fhv\|4fhv]], [[4fhw\|4fhw]], [[4fhx\|4fhx]], [[4fhy\|4fhy]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cid1, SPAC19D5.03 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Schizosaccharomyces pombe 972h-])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fhp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fhp RCSB], [http://www.ebi.ac.uk/pdbsum/4fhp PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CID1_SCHPO CID1_SCHPO]] Involved in cell cycle arrest where in association with crb2/rhp9 and chk1 it inhibits unscheduled mitosis.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Polyuridylation is emerging as a ubiquitous post-translational modification with important roles in multiple aspects of RNA metabolism. These poly (U) tails are added by poly (U) polymerases with homology to poly (A) polymerases; nevertheless, the selection for UTP over ATP remains enigmatic. We report the structures of poly (U) polymerase Cid1 from Schizoscaccharomyces pombe alone and in complex with UTP, CTP, GTP and 3'-dATP. These structures reveal that each of the 4 nt can be accommodated at the active site; however, differences exist that suggest how the polymerase selects UTP over the other nucleotides. Furthermore, we find that Cid1 shares a number of common UTP recognition features with the kinetoplastid terminal uridyltransferases. Kinetic analysis of Cid1's activity for its preferred substrates, UTP and ATP, reveal a clear preference for UTP over ATP. Ultimately, we show that a single histidine in the active site plays a pivotal role for poly (U) activity. Notably, this residue is typically replaced by an asparagine residue in Cid1-family poly (A) polymerases. By mutating this histidine to an asparagine residue in Cid1, we diminished Cid1's activity for UTP addition and improved ATP incorporation, supporting that this residue is important for UTP selectivity.

-	~~{{STRUCTURE_4fhp\| PDB=4fhp \| SCENE= }}~~	+	Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity.,Lunde BM, Magler I, Meinhart A Nucleic Acids Res. 2012 Aug 9. PMID:22885303<ref>PMID:22885303</ref>

-	~~===Crystal structures~~ of the ~~Cid1 poly (~~U~~) polymerase reveal the mechanism for UTP selectivity - CaUTP bound===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-		+	==See Also==
-	==~~About this Structure~~==	+	*[[RNA polymerase\|RNA polymerase]]
-	[[~~4fhp~~]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FHP OCA].	+	== References ==
-		+	<references/>
-	==~~Reference~~==	+	__TOC__
-	<~~ref group="xtra">PMID:022885303<~~/~~ref~~><~~references group="xtra"~~/>	+	</StructureSection>
	[[Category: Schizosaccharomyces pombe 972h-]]		[[Category: Schizosaccharomyces pombe 972h-]]
-	[[Category: Lunde, B M.]]	+	[[Category: Lunde, B M]]
-	[[Category: Magler, I.]]	+	[[Category: Magler, I]]
-	[[Category: Meinhart, A.]]	+	[[Category: Meinhart, A]]
	[[Category: Nucleotidyltransferase]]		[[Category: Nucleotidyltransferase]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 14:15, 8 November 2012

2012-11-08T14:15:30Z

←Older revision		Revision as of 14:15, 8 November 2012
Line 1:		Line 1:
-	[[Image:4fhp.~~jpg~~\|left\|200px]]	+	[[Image:4fhp.png\|left\|200px]]

	{{STRUCTURE_4fhp\| PDB=4fhp \| SCENE= }}		{{STRUCTURE_4fhp\| PDB=4fhp \| SCENE= }}
Line 5:		Line 5:
	===Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - CaUTP bound===		===Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - CaUTP bound===

-	{{ABSTRACT_PUBMED_22885303}}

	==About this Structure==		==About this Structure==
-	[[4fhp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Schizosaccharomyces_pombe~~ Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FHP OCA].	+	[[4fhp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FHP OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:022885303</ref><references group="xtra"/>		<ref group="xtra">PMID:022885303</ref><references group="xtra"/>
-	[[Category: Schizosaccharomyces pombe]]	+	[[Category: Schizosaccharomyces pombe 972h-]]
	[[Category: Lunde, B M.]]		[[Category: Lunde, B M.]]
	[[Category: Magler, I.]]		[[Category: Magler, I.]]

OCA at 05:08, 29 August 2012

2012-08-29T05:08:40Z

←Older revision		Revision as of 05:08, 29 August 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4fhp.jpg\|left\|200px]]

-	~~The entry~~ 4fhp ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_4fhp\| PDB=4fhp \| SCENE= }}

-	~~Authors: Lunde, B.M., Magler, I., Meinhart, A.~~	+	===Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - CaUTP bound===

-	~~Description~~: ~~Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity~~ -~~CaUTP bound~~	+	{{ABSTRACT_PUBMED_22885303}}
		+
		+	==About this Structure==
		+	[[4fhp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FHP OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022885303</ref><references group="xtra"/>
		+	[[Category: Schizosaccharomyces pombe]]
		+	[[Category: Lunde, B M.]]
		+	[[Category: Magler, I.]]
		+	[[Category: Meinhart, A.]]
		+	[[Category: Nucleotidyltransferase]]
		+	[[Category: Transferase]]

OCA at 05:24, 27 June 2012

2012-06-27T05:24:22Z

←Older revision		Revision as of 05:24, 27 June 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4fhp is ON HOLD	+	The entry 4fhp is ON HOLD until Paper Publication

	Authors: Lunde, B.M., Magler, I., Meinhart, A.		Authors: Lunde, B.M., Magler, I., Meinhart, A.

-	Description: Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity	+	Description: Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity -CaUTP bound

OCA at 07:26, 20 June 2012

2012-06-20T07:26:05Z

←Older revision		Revision as of 07:26, 20 June 2012
Line 3:		Line 3:
	The entry 4fhp is ON HOLD		The entry 4fhp is ON HOLD

-	Authors: Lunde, B.M, Magler, I., Meinhart, A.	+	Authors: Lunde, B.M., Magler, I., Meinhart, A.

	Description: Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity		Description: Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity

OCA: Protected "4fhp" [edit=sysop:move=sysop]

2012-06-13T05:52:59Z

Protected "4fhp" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:52, 13 June 2012

OCA: New page: '''Unreleased structure''' The entry 4fhp is ON HOLD Authors: Lunde, B.M, Magler, I., Meinhart, A. Description: Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism ...

2012-06-13T05:52:58Z

New page: '''Unreleased structure''' The entry 4fhp is ON HOLD Authors: Lunde, B.M, Magler, I., Meinhart, A. Description: Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism ...

New page

'''Unreleased structure'''

The entry 4fhp is ON HOLD

Authors: Lunde, B.M, Magler, I., Meinhart, A.

Description: Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity