4fum - Revision history

OCA at 20:10, 19 October 2022

2022-10-19T20:10:51Z

←Older revision		Revision as of 20:10, 19 October 2022
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	==Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms==		==Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms==
-	<StructureSection load='4fum' size='340' side='right' caption='[[4fum]], [[Resolution\|resolution]] 2.40Å' scene=''>	+	<StructureSection load='4fum' size='340' side='right'caption='[[4fum]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4fum]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Staeq Staeq~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FUM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4FUM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4fum]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_epidermidis_RP62A Staphylococcus epidermidis RP62A]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FUM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FUM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~SCN~~:~~THIOCYANATE+ION~~'>~~SCN~~</scene>, <scene name='pdbligand=ZN:~~ZINC~~+ION'>ZN</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=~~MSE~~:~~SELENOMETHIONINE~~'>~~MSE~~</scene>~~</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fum OCA], [https://pdbe.org/4fum PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fum RCSB], [https://www.ebi.ac.uk/pdbsum/4fum PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fum ProSAT]</span></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fun\|4fun]], [[4fuo\|4fuo]], [[4fup\|4fup]]</td></tr>~~	+
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aap, SERP2398 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=176279 STAEQ])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4fum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fum OCA], [~~http~~://pdbe.org/4fum PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4fum RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4fum PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4fum ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q5HKE8_STAEQ Q5HKE8_STAEQ]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Staeq~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Conrady, D G~~]]	+	[[Category: Staphylococcus epidermidis RP62A]]
-	[[Category: ~~Herr, A B~~]]	+	[[Category: Conrady DG]]
-	[[Category: ~~Wilson, J J~~]]	+	[[Category: Herr AB]]
-	[[Category: ~~Freestanding beta sheet]]~~	+	[[Category: Wilson JJ]]
-	~~[[Category: Hydrophilic protein]]~~	+
-	~~[[Category: Intercellular adhesion]]~~	+
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Non-globular]]~~	+
-	~~[[Category: Zinc dependent dimer~~]]	+

OCA at 18:41, 11 August 2016

2016-08-11T18:41:04Z

←Older revision		Revision as of 18:41, 11 August 2016
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		+
	==Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms==		==Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms==
	<StructureSection load='4fum' size='340' side='right' caption='[[4fum]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='4fum' size='340' side='right' caption='[[4fum]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4fum]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Staphylococcus_epidermidis_rp62a Staphylococcus epidermidis rp62a~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FUM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FUM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4fum]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staeq Staeq]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FUM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FUM FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fun\|4fun]], [[4fuo\|4fuo]], [[4fup\|4fup]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fun\|4fun]], [[4fuo\|4fuo]], [[4fup\|4fup]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aap, SERP2398 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=176279 ~~Staphylococcus epidermidis RP62A~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aap, SERP2398 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=176279 STAEQ])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fum OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fum RCSB], [http://www.ebi.ac.uk/pdbsum/4fum PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fum OCA], [http://pdbe.org/4fum PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fum RCSB], [http://www.ebi.ac.uk/pdbsum/4fum PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fum ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4fum" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Staphylococcus epidermidis rp62a~~]]	+	[[Category: Staeq]]
	[[Category: Conrady, D G]]		[[Category: Conrady, D G]]
	[[Category: Herr, A B]]		[[Category: Herr, A B]]

OCA at 13:37, 4 January 2015

2015-01-04T13:37:22Z

←Older revision		Revision as of 13:37, 4 January 2015
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-	[[~~Image:~~4fum.~~png~~\|~~left~~\|~~200px~~]]	+	==Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms==
		+	<StructureSection load='4fum' size='340' side='right' caption='[[4fum]], [[Resolution\|resolution]] 2.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4fum]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_epidermidis_rp62a Staphylococcus epidermidis rp62a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FUM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FUM FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fun\|4fun]], [[4fuo\|4fuo]], [[4fup\|4fup]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aap, SERP2398 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=176279 Staphylococcus epidermidis RP62A])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fum OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fum RCSB], [http://www.ebi.ac.uk/pdbsum/4fum PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	SignificanceUnder adverse environmental conditions, bacteria can form specialized antibiotic-resistant colonies called "biofilms." In Staphylococcus epidermidis biofilms, a protein, Aap, links bacterial cells together but does so only in the presence of zinc ions. We have determined the atomic structure of an adhesive portion of Aap bound to zinc. The protein adopts an elongated, flexible fold with zinc ions bridging two protein chains. The mode of assembly indicates that Aap is likely to form twisted rope-like structures between bacterial cells. These data provide clues about regions of the protein that could be targeted to prevent intercellular adhesion in the developing biofilm.

-	~~{{STRUCTURE_4fum\| PDB=4fum \| SCENE= }}~~	+	Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms.,Conrady DG, Wilson JJ, Herr AB Proc Natl Acad Sci U S A. 2012 Dec 31. PMID:23277549<ref>PMID:23277549</ref>

-	~~===Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_23277549}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[4fum]] is a 1 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Staphylococcus_epidermidis_rp62a Staphylococcus epidermidis rp62a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FUM OCA].~~	+	</StructureSection>
	[[Category: Staphylococcus epidermidis rp62a]]		[[Category: Staphylococcus epidermidis rp62a]]
-	[[Category: Conrady, D G.]]	+	[[Category: Conrady, D G]]
-	[[Category: Herr, A B.]]	+	[[Category: Herr, A B]]
-	[[Category: Wilson, J J.]]	+	[[Category: Wilson, J J]]
	[[Category: Freestanding beta sheet]]		[[Category: Freestanding beta sheet]]
	[[Category: Hydrophilic protein]]		[[Category: Hydrophilic protein]]

OCA at 12:50, 30 January 2013

2013-01-30T12:50:34Z

←Older revision		Revision as of 12:50, 30 January 2013
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-	[[Image:4fum.~~jpg~~\|left\|200px]]	+	[[Image:4fum.png\|left\|200px]]

	{{STRUCTURE_4fum\| PDB=4fum \| SCENE= }}		{{STRUCTURE_4fum\| PDB=4fum \| SCENE= }}

OCA at 08:47, 16 January 2013

2013-01-16T08:47:22Z

←Older revision		Revision as of 08:47, 16 January 2013
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-	~~'''Unreleased structure'''~~	+	[[Image:4fum.jpg\|left\|200px]]

-	~~The entry~~ 4fum ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_4fum\| PDB=4fum \| SCENE= }}

-	~~Authors: Conrady, D.G., Wilson, J.J., Herr, A.B.~~	+	===Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms===

-	~~Description~~: ~~Structural basis for Zn2+~~-~~dependent intercellular~~ adhesion ~~in staphylococcal biofilms~~	+	{{ABSTRACT_PUBMED_23277549}}
		+
		+	==About this Structure==
		+	[[4fum]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_epidermidis_rp62a Staphylococcus epidermidis rp62a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FUM OCA].
		+	[[Category: Staphylococcus epidermidis rp62a]]
		+	[[Category: Conrady, D G.]]
		+	[[Category: Herr, A B.]]
		+	[[Category: Wilson, J J.]]
		+	[[Category: Freestanding beta sheet]]
		+	[[Category: Hydrophilic protein]]
		+	[[Category: Intercellular adhesion]]
		+	[[Category: Membrane protein]]
		+	[[Category: Non-globular]]
		+	[[Category: Zinc dependent dimer]]

OCA at 05:20, 15 August 2012

2012-08-15T05:20:30Z

←Older revision		Revision as of 05:20, 15 August 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4fum is ON HOLD	+	The entry 4fum is ON HOLD until Paper Publication

	Authors: Conrady, D.G., Wilson, J.J., Herr, A.B.		Authors: Conrady, D.G., Wilson, J.J., Herr, A.B.

	Description: Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms		Description: Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms

OCA: Protected "4fum" [edit=sysop:move=sysop]

2012-07-04T07:23:41Z

Protected "4fum" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:23, 4 July 2012

OCA: New page: '''Unreleased structure''' The entry 4fum is ON HOLD Authors: Conrady, D.G., Wilson, J.J., Herr, A.B. Description: Structural basis for Zn2+-dependent intercellular adhesion in staphyl...

2012-07-04T07:23:40Z

New page: '''Unreleased structure''' The entry 4fum is ON HOLD Authors: Conrady, D.G., Wilson, J.J., Herr, A.B. Description: Structural basis for Zn2+-dependent intercellular adhesion in staphyl...

New page

'''Unreleased structure'''

The entry 4fum is ON HOLD

Authors: Conrady, D.G., Wilson, J.J., Herr, A.B.

Description: Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms