4fwy - Revision history

OCA at 15:35, 14 March 2024

2024-03-14T15:35:19Z

←Older revision		Revision as of 15:35, 14 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4fwy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FWY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FWY FirstGlance]. <br>		<table><tr><td colspan='2'>[[4fwy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FWY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FWY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fwy OCA], [https://pdbe.org/4fwy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fwy RCSB], [https://www.ebi.ac.uk/pdbsum/4fwy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fwy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fwy OCA], [https://pdbe.org/4fwy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fwy RCSB], [https://www.ebi.ac.uk/pdbsum/4fwy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fwy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.		[https://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	No spare Tyr: Rational design of functional enzymes with a high number of turnovers is a challenge, especially those with a complex active site, such as respiratory oxidases. Introducing two His and one Tyr residues into myoglobin resulted in enzymes that reduce O(2) to H(2) O with more than 1000 turnovers (red line, see scheme) and minimal release of reactive oxygen species. The positioning of the Tyr residue is critical for activity.
-
-	A Designed Functional Metalloenzyme that Reduces O(2) to H(2) O with Over One Thousand Turnovers.,Miner KD, Mukherjee A, Gao YG, Null EL, Petrik ID, Zhao X, Yeung N, Robinson H, Lu Y Angew Chem Int Ed Engl. 2012 Jun 4;51(23):5589-92. doi: 10.1002/anie.201201981., Epub 2012 Apr 26. PMID:22539151<ref>PMID:22539151</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4fwy" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Myoglobin 3D structures\|Myoglobin 3D structures]]		*[[Myoglobin 3D structures\|Myoglobin 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 20:13, 19 October 2022

2022-10-19T20:13:52Z

←Older revision		Revision as of 20:13, 19 October 2022
Line 1:		Line 1:

	==F33Y CuB myoglobin (F33Y L29H F43H sperm whale myoglobin) with copper bound==		==F33Y CuB myoglobin (F33Y L29H F43H sperm whale myoglobin) with copper bound==
-	<StructureSection load='4fwy' size='340' side='right' caption='[[4fwy]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='4fwy' size='340' side='right'caption='[[4fwy]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4fwy]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Phycd Phycd~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FWY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4FWY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4fwy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FWY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FWY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fwx\|4fwx]], [[4fwz\|4fwz]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fwy OCA], [https://pdbe.org/4fwy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fwy RCSB], [https://www.ebi.ac.uk/pdbsum/4fwy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fwy ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9755 PHYCD])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4fwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fwy OCA], [~~http~~://pdbe.org/4fwy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4fwy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4fwy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4fwy ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC]] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.	+	[https://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 20:

	==See Also==		==See Also==
-	*[[Myoglobin\|Myoglobin]]	+	*[[Myoglobin 3D structures\|Myoglobin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Phycd~~]]	+	[[Category: Large Structures]]
-	[[Category: Gao, Y G]]	+	[[Category: Physeter catodon]]
-	[[Category: Lu, Y]]	+	[[Category: Gao Y-G]]
-	[[Category: Miner~~, K D~~]]	+	[[Category: Lu Y]]
-	[[Category: Petrik~~, I D~~]]	+	[[Category: Miner KD]]
-	[[Category: Robinson, H]]	+	[[Category: Petrik ID]]
-	~~[[Category: Globin]]~~	+	[[Category: Robinson H]]
-	~~[[Category: Oxidase]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 00:17, 5 August 2016

2016-08-05T00:17:04Z

←Older revision		Revision as of 00:17, 5 August 2016
Line 1:		Line 1:
		+
	==F33Y CuB myoglobin (F33Y L29H F43H sperm whale myoglobin) with copper bound==		==F33Y CuB myoglobin (F33Y L29H F43H sperm whale myoglobin) with copper bound==
	<StructureSection load='4fwy' size='340' side='right' caption='[[4fwy]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='4fwy' size='340' side='right' caption='[[4fwy]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4fwy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Physeter_catodon Physeter catodon~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FWY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FWY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4fwy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Phycd Phycd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FWY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FWY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fwx\|4fwx]], [[4fwz\|4fwz]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fwx\|4fwx]], [[4fwz\|4fwz]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9755 ~~Physeter catodon~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9755 PHYCD])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fwy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fwy RCSB], [http://www.ebi.ac.uk/pdbsum/4fwy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fwy OCA], [http://pdbe.org/4fwy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fwy RCSB], [http://www.ebi.ac.uk/pdbsum/4fwy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fwy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4fwy" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 25:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Physeter catodon~~]]	+	[[Category: Phycd]]
	[[Category: Gao, Y G]]		[[Category: Gao, Y G]]
	[[Category: Lu, Y]]		[[Category: Lu, Y]]

OCA at 21:06, 24 December 2014

2014-12-24T21:06:04Z

←Older revision		Revision as of 21:06, 24 December 2014
Line 1:		Line 1:
-	[[~~Image:~~4fwy.~~jpg~~\|~~left~~\|~~200px~~]]	+	==F33Y CuB myoglobin (F33Y L29H F43H sperm whale myoglobin) with copper bound==
		+	<StructureSection load='4fwy' size='340' side='right' caption='[[4fwy]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4fwy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FWY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FWY FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fwx\|4fwx]], [[4fwz\|4fwz]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9755 Physeter catodon])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fwy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fwy RCSB], [http://www.ebi.ac.uk/pdbsum/4fwy PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC]] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	No spare Tyr: Rational design of functional enzymes with a high number of turnovers is a challenge, especially those with a complex active site, such as respiratory oxidases. Introducing two His and one Tyr residues into myoglobin resulted in enzymes that reduce O(2) to H(2) O with more than 1000 turnovers (red line, see scheme) and minimal release of reactive oxygen species. The positioning of the Tyr residue is critical for activity.

-	~~{{STRUCTURE_4fwy\| PDB=4fwy \| SCENE= }}~~	+	A Designed Functional Metalloenzyme that Reduces O(2) to H(2) O with Over One Thousand Turnovers.,Miner KD, Mukherjee A, Gao YG, Null EL, Petrik ID, Zhao X, Yeung N, Robinson H, Lu Y Angew Chem Int Ed Engl. 2012 Jun 4;51(23):5589-92. doi: 10.1002/anie.201201981., Epub 2012 Apr 26. PMID:22539151<ref>PMID:22539151</ref>

-	~~===F33Y CuB myoglobin (F33Y L29H F43H sperm whale myoglobin) with copper bound===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_22539151}}~~	+	==See Also==
-		+	*[[Myoglobin\|Myoglobin]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~4fwy~~]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FWY OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:022539151<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Physeter catodon]]		[[Category: Physeter catodon]]
-	[[Category: Gao, Y G.]]	+	[[Category: Gao, Y G]]
-	[[Category: Lu, Y.]]	+	[[Category: Lu, Y]]
-	[[Category: Miner, K D.]]	+	[[Category: Miner, K D]]
-	[[Category: Petrik, I D.]]	+	[[Category: Petrik, I D]]
-	[[Category: Robinson, H.]]	+	[[Category: Robinson, H]]
	[[Category: Globin]]		[[Category: Globin]]
	[[Category: Oxidase]]		[[Category: Oxidase]]
	[[Category: Transport protein]]		[[Category: Transport protein]]

OCA at 05:22, 18 July 2012

2012-07-18T05:22:37Z

←Older revision		Revision as of 05:22, 18 July 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4fwy.jpg\|left\|200px]]

-	~~The entry~~ 4fwy ~~is ON HOLD~~	+	{{STRUCTURE_4fwy\| PDB=4fwy \| SCENE= }}

-	~~Authors: Gao, Y.-G., Robinson, H., Petrik, I.D., Miner, K.D., Lu, Y.~~	+	===F33Y CuB myoglobin (F33Y L29H F43H sperm whale myoglobin) with copper bound===

-	~~Description: F33Y CuB myoglobin (F33Y L29H F43H sperm whale myoglobin)~~ with ~~copper bound~~	+	{{ABSTRACT_PUBMED_22539151}}
		+
		+	==About this Structure==
		+	[[4fwy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FWY OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022539151</ref><references group="xtra"/>
		+	[[Category: Physeter catodon]]
		+	[[Category: Gao, Y G.]]
		+	[[Category: Lu, Y.]]
		+	[[Category: Miner, K D.]]
		+	[[Category: Petrik, I D.]]
		+	[[Category: Robinson, H.]]
		+	[[Category: Globin]]
		+	[[Category: Oxidase]]
		+	[[Category: Transport protein]]

OCA: Protected "4fwy" [edit=sysop:move=sysop]

2012-07-11T07:52:15Z

Protected "4fwy" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:52, 11 July 2012

OCA: New page: '''Unreleased structure''' The entry 4fwy is ON HOLD Authors: Gao, Y.-G., Robinson, H., Petrik, I.D., Miner, K.D., Lu, Y. Description: F33Y CuB myoglobin (F33Y L29H F43H sperm whale my...

2012-07-11T07:52:14Z

New page: '''Unreleased structure''' The entry 4fwy is ON HOLD Authors: Gao, Y.-G., Robinson, H., Petrik, I.D., Miner, K.D., Lu, Y. Description: F33Y CuB myoglobin (F33Y L29H F43H sperm whale my...

New page

'''Unreleased structure'''

The entry 4fwy is ON HOLD

Authors: Gao, Y.-G., Robinson, H., Petrik, I.D., Miner, K.D., Lu, Y.

Description: F33Y CuB myoglobin (F33Y L29H F43H sperm whale myoglobin) with copper bound