4fyk - Revision history

OCA at 11:24, 1 March 2024

2024-03-01T11:24:11Z

←Older revision		Revision as of 11:24, 1 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4fyk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FYK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FYK FirstGlance]. <br>		<table><tr><td colspan='2'>[[4fyk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FYK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FYK FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SRA:ADENOSINE+-5-THIO-MONOPHOSPHATE'>SRA</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.79Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SRA:ADENOSINE+-5-THIO-MONOPHOSPHATE'>SRA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fyk OCA], [https://pdbe.org/4fyk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fyk RCSB], [https://www.ebi.ac.uk/pdbsum/4fyk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fyk ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fyk OCA], [https://pdbe.org/4fyk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fyk RCSB], [https://www.ebi.ac.uk/pdbsum/4fyk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fyk ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/DNPH1_RAT DNPH1_RAT] Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.<ref>PMID:17234634</ref>		[https://www.uniprot.org/uniprot/DNPH1_RAT DNPH1_RAT] Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.<ref>PMID:17234634</ref>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Rcl is a novel N-glycoside hydrolase found in mammals that shows specificity for the hydrolysis of 5'-monophosphate nucleotides. Its role in nucleotide catabolism and the resulting production of 2-deoxyribose 5-phosphate has suggested that it might fuel cancer growth. Its expression is regulated by c-Myc, but its role as an oncoprotein remains to be clarified. In parallel, various nucleosides have been shown to acquire pro-apoptotic properties upon 5'-monophosphorylation in cells. These include triciribine, a tricyclic nucleoside analogue that is currently in clinical trials in combination with a farnesyltransferase inhibitor. Similarly, an N(6)-alkyl-AMP has been shown to be cytotoxic. Interestingly, Rcl has been shown to be inhibited by such compounds in vitro. In order to gain better insight into the precise ligand-recognition determinants, the crystallization of Rcl with these nucleotide analogues was attempted. The first crystal structure of Rcl was solved by molecular replacement using its NMR structure in combination with distantly related crystal structures. The structures of Rcl bound to two other nucleotides were then solved by molecular replacement using the previous crystal structure as a template. The resulting structures, solved at high resolution, led to a clear characterization of the protein-ligand interactions that will guide further rational drug design.
-
-	Structure of the oncoprotein Rcl bound to three nucleotide analogues.,Padilla A, Amiable C, Pochet S, Kaminski PA, Labesse G Acta Crystallogr D Biol Crystallogr. 2013 Feb;69(Pt 2):247-55. doi:, 10.1107/S0907444912045039. Epub 2013 Jan 19. PMID:23385460<ref>PMID:23385460</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4fyk" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 20:15, 19 October 2022

2022-10-19T20:15:31Z

←Older revision		Revision as of 20:15, 19 October 2022
Line 1:		Line 1:

	==Crystal structure of rcl with 5'-phiosphorothioate-adenosine==		==Crystal structure of rcl with 5'-phiosphorothioate-adenosine==
-	<StructureSection load='4fyk' size='340' side='right' caption='[[4fyk]], [[Resolution\|resolution]] 1.79Å' scene=''>	+	<StructureSection load='4fyk' size='340' side='right'caption='[[4fyk]], [[Resolution\|resolution]] 1.79Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4fyk]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Buffalo_rat Buffalo rat~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FYK OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4FYK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4fyk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FYK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FYK FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SRA:ADENOSINE+-5-THIO-MONOPHOSPHATE'>SRA</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SRA:ADENOSINE+-5-THIO-MONOPHOSPHATE'>SRA</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fyh\|4fyh]], [[4fyi\|4fyi]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fyk OCA], [https://pdbe.org/4fyk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fyk RCSB], [https://www.ebi.ac.uk/pdbsum/4fyk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fyk ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rcl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4fyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fyk OCA], [~~http~~://pdbe.org/4fyk PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4fyk RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4fyk PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4fyk ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/DNPH1_RAT DNPH1_RAT]] Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.<ref>PMID:17234634</ref>	+	[https://www.uniprot.org/uniprot/DNPH1_RAT DNPH1_RAT] Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.<ref>PMID:17234634</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Buffalo rat~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Kaminski, P A~~]]	+	[[Category: Rattus norvegicus]]
-	[[Category: ~~Labesse, G~~]]	+	[[Category: Kaminski PA]]
-	[[Category: ~~Padilla, A~~]]	+	[[Category: Labesse G]]
-	[[Category: ~~Deoxyribonucleoside 5'-monophosphate n-glycosidase]]~~	+	[[Category: Padilla A]]
-	~~[[Category: Hydrolase~~]]	+

OCA at 20:54, 4 August 2016

2016-08-04T20:54:09Z

←Older revision		Revision as of 20:54, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of rcl with 5'-phiosphorothioate-adenosine==		==Crystal structure of rcl with 5'-phiosphorothioate-adenosine==
	<StructureSection load='4fyk' size='340' side='right' caption='[[4fyk]], [[Resolution\|resolution]] 1.79Å' scene=''>		<StructureSection load='4fyk' size='340' side='right' caption='[[4fyk]], [[Resolution\|resolution]] 1.79Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4fyk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Rattus_norvegicus Rattus norvegicus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FYK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FYK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4fyk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FYK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FYK FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SRA:ADENOSINE+-5-THIO-MONOPHOSPHATE'>SRA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SRA:ADENOSINE+-5-THIO-MONOPHOSPHATE'>SRA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fyh\|4fyh]], [[4fyi\|4fyi]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fyh\|4fyh]], [[4fyi\|4fyi]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rcl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 ~~Rattus norvegicus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rcl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fyk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fyk RCSB], [http://www.ebi.ac.uk/pdbsum/4fyk PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fyk OCA], [http://pdbe.org/4fyk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fyk RCSB], [http://www.ebi.ac.uk/pdbsum/4fyk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fyk ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~RCL_RAT RCL_RAT~~]] Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.<ref>PMID:17234634</ref>	+	[[http://www.uniprot.org/uniprot/DNPH1_RAT DNPH1_RAT]] Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.<ref>PMID:17234634</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4fyk" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Rattus norvegicus~~]]	+	[[Category: Buffalo rat]]
	[[Category: Kaminski, P A]]		[[Category: Kaminski, P A]]
	[[Category: Labesse, G]]		[[Category: Labesse, G]]

OCA at 13:05, 25 December 2014

2014-12-25T13:05:23Z

←Older revision		Revision as of 13:05, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fyk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fyk RCSB], [http://www.ebi.ac.uk/pdbsum/4fyk PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fyk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fyk RCSB], [http://www.ebi.ac.uk/pdbsum/4fyk PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RCL_RAT RCL_RAT]] Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.<ref>PMID:17234634</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 17:39, 9 December 2014

2014-12-09T17:39:51Z

←Older revision		Revision as of 17:39, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~4fyk.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of rcl with 5'-phiosphorothioate-adenosine==
		+	<StructureSection load='4fyk' size='340' side='right' caption='[[4fyk]], [[Resolution\|resolution]] 1.79Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4fyk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FYK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FYK FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SRA:ADENOSINE+-5-THIO-MONOPHOSPHATE'>SRA</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4fyh\|4fyh]], [[4fyi\|4fyi]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rcl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fyk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fyk RCSB], [http://www.ebi.ac.uk/pdbsum/4fyk PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Rcl is a novel N-glycoside hydrolase found in mammals that shows specificity for the hydrolysis of 5'-monophosphate nucleotides. Its role in nucleotide catabolism and the resulting production of 2-deoxyribose 5-phosphate has suggested that it might fuel cancer growth. Its expression is regulated by c-Myc, but its role as an oncoprotein remains to be clarified. In parallel, various nucleosides have been shown to acquire pro-apoptotic properties upon 5'-monophosphorylation in cells. These include triciribine, a tricyclic nucleoside analogue that is currently in clinical trials in combination with a farnesyltransferase inhibitor. Similarly, an N(6)-alkyl-AMP has been shown to be cytotoxic. Interestingly, Rcl has been shown to be inhibited by such compounds in vitro. In order to gain better insight into the precise ligand-recognition determinants, the crystallization of Rcl with these nucleotide analogues was attempted. The first crystal structure of Rcl was solved by molecular replacement using its NMR structure in combination with distantly related crystal structures. The structures of Rcl bound to two other nucleotides were then solved by molecular replacement using the previous crystal structure as a template. The resulting structures, solved at high resolution, led to a clear characterization of the protein-ligand interactions that will guide further rational drug design.

-	~~{{STRUCTURE_4fyk\| PDB=4fyk \| SCENE= }}~~	+	Structure of the oncoprotein Rcl bound to three nucleotide analogues.,Padilla A, Amiable C, Pochet S, Kaminski PA, Labesse G Acta Crystallogr D Biol Crystallogr. 2013 Feb;69(Pt 2):247-55. doi:, 10.1107/S0907444912045039. Epub 2013 Jan 19. PMID:23385460<ref>PMID:23385460</ref>

-	~~===Crystal structure~~ of ~~rcl with 5'-phiosphorothioate-adenosine===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_23385460}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[4fyk]] is a 4 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FYK OCA].~~	+	</StructureSection>
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
-	[[Category: Kaminski, P A.]]	+	[[Category: Kaminski, P A]]
-	[[Category: Labesse, G.]]	+	[[Category: Labesse, G]]
-	[[Category: Padilla, A.]]	+	[[Category: Padilla, A]]
	[[Category: Deoxyribonucleoside 5'-monophosphate n-glycosidase]]		[[Category: Deoxyribonucleoside 5'-monophosphate n-glycosidase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 12:42, 20 February 2013

2013-02-20T12:42:17Z

←Older revision		Revision as of 12:42, 20 February 2013
Line 5:		Line 5:
	===Crystal structure of rcl with 5'-phiosphorothioate-adenosine===		===Crystal structure of rcl with 5'-phiosphorothioate-adenosine===

		+	{{ABSTRACT_PUBMED_23385460}}

	==About this Structure==		==About this Structure==

OCA at 12:50, 30 January 2013

2013-01-30T12:50:47Z

←Older revision		Revision as of 12:50, 30 January 2013
Line 1:		Line 1:
-	[[Image:4fyk.~~jpg~~\|left\|200px]]	+	[[Image:4fyk.png\|left\|200px]]

	{{STRUCTURE_4fyk\| PDB=4fyk \| SCENE= }}		{{STRUCTURE_4fyk\| PDB=4fyk \| SCENE= }}

OCA at 09:35, 2 January 2013

2013-01-02T09:35:39Z

←Older revision		Revision as of 09:35, 2 January 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4fyk.jpg\|left\|200px]]

-	~~The entry~~ 4fyk ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_4fyk\| PDB=4fyk \| SCENE= }}

-	~~Authors: Labesse, G., Padilla, A., Kaminski, P.A.~~	+	===Crystal structure of rcl with 5'-phiosphorothioate-adenosine===

-	~~Description: Crystal~~ structure ~~of rcl~~ with 5'-~~phiosphorothioate~~-~~adenosine~~	+
		+	==About this Structure==
		+	[[4fyk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FYK OCA].
		+	[[Category: Rattus norvegicus]]
		+	[[Category: Kaminski, P A.]]
		+	[[Category: Labesse, G.]]
		+	[[Category: Padilla, A.]]
		+	[[Category: Deoxyribonucleoside 5'-monophosphate n-glycosidase]]
		+	[[Category: Hydrolase]]

OCA at 04:55, 8 August 2012

2012-08-08T04:55:56Z

←Older revision		Revision as of 04:55, 8 August 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4fyk is ON HOLD	+	The entry 4fyk is ON HOLD until Paper Publication

	Authors: Labesse, G., Padilla, A., Kaminski, P.A.		Authors: Labesse, G., Padilla, A., Kaminski, P.A.

	Description: Crystal structure of rcl with 5'-phiosphorothioate-adenosine		Description: Crystal structure of rcl with 5'-phiosphorothioate-adenosine

OCA at 06:49, 25 July 2012

2012-07-25T06:49:16Z

←Older revision		Revision as of 06:49, 25 July 2012
Line 5:		Line 5:
	Authors: Labesse, G., Padilla, A., Kaminski, P.A.		Authors: Labesse, G., Padilla, A., Kaminski, P.A.

-	Description: ~~CRYSTAL STRUCTURE OF RCL WITH~~ 5'-~~PHIOSPHOROTHIOATE~~-~~ADENOSINE~~	+	Description: Crystal structure of rcl with 5'-phiosphorothioate-adenosine