4g7e - Revision history

OCA at 20:28, 19 October 2022

2022-10-19T20:28:54Z

←Older revision		Revision as of 20:28, 19 October 2022
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	<StructureSection load='4g7e' size='340' side='right'caption='[[4g7e]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='4g7e' size='340' side='right'caption='[[4g7e]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4g7e]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Cajanus_cajan Cajanus cajan]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G7E OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4G7E FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4g7e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cajanus_cajan Cajanus cajan]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G7E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G7E FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
-	~~<tr~~ id~~='NonStdRes'><td class~~="~~sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat~~"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene><~~/td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g7e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g7e OCA], [https://pdbe.org/4g7e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g7e RCSB], [https://www.ebi.ac.uk/pdbsum/4g7e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g7e ProSAT]</span></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[http://en.wikipedia.org/wiki/Urease Urease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.5 3.5.1.5]~~ </~~span~~></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4g7e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g7e OCA], [~~http~~://pdbe.org/4g7e PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4g7e RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4g7e PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4g7e ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/I3PA93_CAJCA I3PA93_CAJCA]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	==See Also==		==See Also==
-	*[[Urease\|Urease]]	+	*[[Urease 3D structures\|Urease 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	[[Category: Cajanus cajan]]		[[Category: Cajanus cajan]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Urease]]~~	+	[[Category: Balasubramanian A]]
-	[[Category: Balasubramanian, A]]	+	[[Category: Ponnuraj K]]
-	[[Category: Ponnuraj, K]]	+
-	~~[[Category: B domain]]~~	+
-	~~[[Category: Carbon di-oxide]]~~	+
-	~~[[Category: Catalyzes urea hydrolysis to ammonia]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Pigeon pea]]~~	+
-	~~[[Category: Tim barrel domain~~]]	+

OCA at 07:45, 27 March 2019

2019-03-27T07:45:00Z

←Older revision		Revision as of 07:45, 27 March 2019
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	==Crystal structure of pigeon pea urease==		==Crystal structure of pigeon pea urease==
-	<StructureSection load='4g7e' size='340' side='right' caption='[[4g7e]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='4g7e' size='340' side='right'caption='[[4g7e]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4g7e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cajanus_cajan Cajanus cajan]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G7E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4G7E FirstGlance]. <br>		<table><tr><td colspan='2'>[[4g7e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cajanus_cajan Cajanus cajan]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G7E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4G7E FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Cajanus cajan]]		[[Category: Cajanus cajan]]
		+	[[Category: Large Structures]]
	[[Category: Urease]]		[[Category: Urease]]
	[[Category: Balasubramanian, A]]		[[Category: Balasubramanian, A]]

OCA at 20:08, 5 August 2016

2016-08-05T20:08:22Z

←Older revision		Revision as of 20:08, 5 August 2016
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		+
	==Crystal structure of pigeon pea urease==		==Crystal structure of pigeon pea urease==
	<StructureSection load='4g7e' size='340' side='right' caption='[[4g7e]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='4g7e' size='340' side='right' caption='[[4g7e]], [[Resolution\|resolution]] 2.20Å' scene=''>
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	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Urease Urease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.5 3.5.1.5] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Urease Urease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.5 3.5.1.5] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g7e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g7e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4g7e RCSB], [http://www.ebi.ac.uk/pdbsum/4g7e PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g7e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g7e OCA], [http://pdbe.org/4g7e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4g7e RCSB], [http://www.ebi.ac.uk/pdbsum/4g7e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4g7e ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4g7e" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 11:11, 21 December 2014

2014-12-21T11:11:37Z

←Older revision		Revision as of 11:11, 21 December 2014
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-	~~{{STRUCTURE_4g7e~~\| ~~PDB~~=4g7e \| ~~SCENE~~= }}	+	==Crystal structure of pigeon pea urease==
-	===~~Crystal~~ structure of pigeon pea urease~~===~~	+	<StructureSection load='4g7e' size='340' side='right' caption='[[4g7e]], [[Resolution\|resolution]] 2.20Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23624166}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4g7e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cajanus_cajan Cajanus cajan]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G7E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4G7E FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Urease Urease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.5 3.5.1.5] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g7e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g7e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4g7e RCSB], [http://www.ebi.ac.uk/pdbsum/4g7e PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Urease is an enzyme that catalyzes the hydrolysis of urea, forming ammonia and carbon dioxide, and is found in plants, microorganisms and invertebrates. Although plant and bacterial ureases are closely related at amino acid and at the structural level, the insecticidal activity is seen only in the plant ureases. In contrast, both plant and bacterial ureases exhibit antifungal activity. These two biological properties are independent of its ureolytic activity. However, till date the mechanism(s) behind the insecticidal and fungicidal activity of ureases are not clearly understood. Here we report the crystal structure of pigeon pea urease (PPU, Cajanus cajan) which is the second structure from the plant source. We have deduced the amino acid sequence of PPU and also report here studies on its stability, insecticidal and antifungal activity. PPU exhibits cellulase activity. Based on the structural analysis of PPU and docking studies with cellopentoase we propose a possible mechanism of antifungal activity of urease.

-	~~==About this Structure==~~	+	Structural and functional studies on urease from pigeon pea (Cajanus cajan).,Balasubramanian A, Durairajpandian V, Elumalai S, Mathivanan N, Munirajan AK, Ponnuraj K Int J Biol Macromol. 2013 Jul;58:301-9. doi: 10.1016/j.ijbiomac.2013.04.055. Epub, 2013 Apr 24. PMID:23624166<ref>PMID:23624166</ref>
-	~~[[4g7e]] is a 2 chain structure with sequence~~ from ~~[http://en.wikipedia.org/wiki/Cajanus_cajan~~ Cajanus cajan]. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=4G7E OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group~~=~~"xtra">PMID:023624166</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+
		+	==See Also==
		+	*[[Urease\|Urease]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Cajanus cajan]]		[[Category: Cajanus cajan]]
	[[Category: Urease]]		[[Category: Urease]]
-	[[Category: Balasubramanian, A.]]	+	[[Category: Balasubramanian, A]]
-	[[Category: Ponnuraj, K.]]	+	[[Category: Ponnuraj, K]]
	[[Category: B domain]]		[[Category: B domain]]
	[[Category: Carbon di-oxide]]		[[Category: Carbon di-oxide]]
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	[[Category: Pigeon pea]]		[[Category: Pigeon pea]]
	[[Category: Tim barrel domain]]		[[Category: Tim barrel domain]]
-	[[Category: Urease]]

OCA at 15:38, 19 June 2013

2013-06-19T15:38:25Z

←Older revision		Revision as of 15:38, 19 June 2013
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-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_4g7e\| PDB=4g7e \| SCENE= }}
		+	===Crystal structure of pigeon pea urease===
		+	{{ABSTRACT_PUBMED_23624166}}

-	~~The entry~~ 4g7e is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
		+	[[4g7e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cajanus_cajan Cajanus cajan]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G7E OCA].

-	~~Authors~~: Balasubramanian, A., Ponnuraj, K.	+	==Reference==
-		+	<ref group="xtra">PMID:023624166</ref><references group="xtra"/><references/>
-	~~Description~~: ~~Crystal structure of pigeon~~ pea ~~urease~~	+	[[Category: Cajanus cajan]]
		+	[[Category: Urease]]
		+	[[Category: Balasubramanian, A.]]
		+	[[Category: Ponnuraj, K.]]
		+	[[Category: B domain]]
		+	[[Category: Carbon di-oxide]]
		+	[[Category: Catalyzes urea hydrolysis to ammonia]]
		+	[[Category: Hydrolase]]
		+	[[Category: Pigeon pea]]
		+	[[Category: Tim barrel domain]]
		+	[[Category: Urease]]

OCA at 20:05, 26 September 2012

2012-09-26T20:05:44Z

←Older revision		Revision as of 20:05, 26 September 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4g7e is ON HOLD	+	The entry 4g7e is ON HOLD until Paper Publication

	Authors: Balasubramanian, A., Ponnuraj, K.		Authors: Balasubramanian, A., Ponnuraj, K.

	Description: Crystal structure of pigeon pea urease		Description: Crystal structure of pigeon pea urease

OCA at 04:58, 8 August 2012

2012-08-08T04:58:21Z

←Older revision		Revision as of 04:58, 8 August 2012
Line 3:		Line 3:
	The entry 4g7e is ON HOLD		The entry 4g7e is ON HOLD

-	Authors: ~~Anuradha~~ Balasubramanian, ~~Karthe~~ Ponnuraj	+	Authors: Balasubramanian, A., Ponnuraj, K.

	Description: Crystal structure of pigeon pea urease		Description: Crystal structure of pigeon pea urease

OCA: Protected "4g7e" [edit=sysop:move=sysop]

2012-08-01T05:29:34Z

Protected "4g7e" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:29, 1 August 2012

OCA: New page: '''Unreleased structure''' The entry 4g7e is ON HOLD Authors: Anuradha Balasubramanian, Karthe Ponnuraj Description: Crystal structure of pigeon pea urease

2012-08-01T05:29:34Z

New page: '''Unreleased structure''' The entry 4g7e is ON HOLD Authors: Anuradha Balasubramanian, Karthe Ponnuraj Description: Crystal structure of pigeon pea urease

New page

'''Unreleased structure'''

The entry 4g7e is ON HOLD

Authors: Anuradha Balasubramanian, Karthe Ponnuraj

Description: Crystal structure of pigeon pea urease