4gp6 - Revision history

OCA at 11:33, 1 March 2024

2024-03-01T11:33:39Z

←Older revision		Revision as of 11:33, 1 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4gp6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetivibrio_thermocellus_ATCC_27405 Acetivibrio thermocellus ATCC 27405]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GP6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GP6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4gp6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetivibrio_thermocellus_ATCC_27405 Acetivibrio thermocellus ATCC 27405]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GP6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GP6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gp6 OCA], [https://pdbe.org/4gp6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gp6 RCSB], [https://www.ebi.ac.uk/pdbsum/4gp6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gp6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gp6 OCA], [https://pdbe.org/4gp6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gp6 RCSB], [https://www.ebi.ac.uk/pdbsum/4gp6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gp6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/A3DJ38_ACET2 A3DJ38_ACET2]		[https://www.uniprot.org/uniprot/A3DJ38_ACET2 A3DJ38_ACET2]
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Pnkp is the end-healing and end-sealing component of an RNA repair system present in diverse bacteria from many phyla. Pnkp is composed of three catalytic modules: an N-terminal polynucleotide 5'-kinase, a central 2',3' phosphatase, and a C-terminal ligase. Here we report the crystal structure of the kinase domain of Clostridium thermocellum Pnkp bound to ATPMg(2+) (substrate complex) and ADPMg(2+) (product complex). The protein consists of a core P-loop phosphotransferase fold embellished by a distinctive homodimerization module composed of secondary structure elements derived from the N and C termini of the kinase domain. ATP is bound within a crescent-shaped groove formed by the P-loop ((15)GSSGSGKST(23)) and an overlying helix-loop-helix "lid." The alpha and beta phosphates are engaged by a network of hydrogen bonds from Thr23 and the P-loop main-chain amides; the gamma phosphate is anchored by the lid residues Arg120 and Arg123. The P-loop lysine (Lys21) and the catalytic Mg(2+) bridge the ATP beta and gamma phosphates. The P-loop serine (Ser22) is the sole enzymic constituent of the octahedral metal coordination complex. Structure-guided mutational analysis underscored the essential contributions of Lys21 and Ser22 in the ATP donor site and Asp38 and Arg41 in the phosphoacceptor site. Our studies suggest a catalytic mechanism whereby Asp38 (as general base) activates the polynucleotide 5'-OH for its nucleophilic attack on the gamma phosphorus and Lys21 and Mg(2+) stabilize the transition state.
-
-	Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system.,Wang LK, Das U, Smith P, Shuman S RNA. 2012 Nov 1. PMID:23118415<ref>PMID:23118415</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4gp6" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 07:09, 26 October 2022

2022-10-26T07:09:02Z

←Older revision		Revision as of 07:09, 26 October 2022
Line 1:		Line 1:

	==Polynucleotide kinase==		==Polynucleotide kinase==
-	<StructureSection load='4gp6' size='340' side='right' caption='[[4gp6]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='4gp6' size='340' side='right'caption='[[4gp6]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4gp6]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Cloth Cloth~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GP6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4GP6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4gp6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetivibrio_thermocellus_ATCC_27405 Acetivibrio thermocellus ATCC 27405]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GP6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GP6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4gp7\|4gp7]], [[3ty5\|3ty5]], [[3ty8\|3ty8]], [[3ty9\|3ty9]], [[4drf\|4drf]], [[4e6n\|4e6n]]</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gp6 OCA], [https://pdbe.org/4gp6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gp6 RCSB], [https://www.ebi.ac.uk/pdbsum/4gp6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gp6 ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Cthe_2768 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=203119 CLOTH])</td></tr>~~	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Polynucleotide_5'-hydroxyl-kinase Polynucleotide 5'-hydroxyl-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.78 2.7.1.78] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4gp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gp6 OCA], [~~http~~://pdbe.org/4gp6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4gp6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4gp6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4gp6 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A3DJ38_ACET2 A3DJ38_ACET2]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Cloth~~]]	+	[[Category: Acetivibrio thermocellus ATCC 27405]]
-	[[Category: ~~Polynucleotide 5'-hydroxyl-kinase~~]]	+	[[Category: Large Structures]]
-	[[Category: Das, U]]	+	[[Category: Das U]]
-	[[Category: Shuman, S]]	+	[[Category: Shuman S]]
-	[[Category: Smith, P]]	+	[[Category: Smith P]]
-	[[Category: Wang~~, L K]]~~	+	[[Category: Wang LK]]
-	~~[[Category: Polynucleotide kinase phosphatase]]~~	+
-	~~[[Category: Rna repair]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 19:52, 15 December 2016

2016-12-15T19:52:49Z

←Older revision		Revision as of 19:52, 15 December 2016
Line 1:		Line 1:
		+
	==Polynucleotide kinase==		==Polynucleotide kinase==
	<StructureSection load='4gp6' size='340' side='right' caption='[[4gp6]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='4gp6' size='340' side='right' caption='[[4gp6]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4gp6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Clostridium_thermocellum_atcc_27405 Clostridium thermocellum atcc 27405~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GP6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GP6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4gp6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cloth Cloth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GP6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GP6 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4gp7\|4gp7]], [[3ty5\|3ty5]], [[3ty8\|3ty8]], [[3ty9\|3ty9]], [[4drf\|4drf]], [[4e6n\|4e6n]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4gp7\|4gp7]], [[3ty5\|3ty5]], [[3ty8\|3ty8]], [[3ty9\|3ty9]], [[4drf\|4drf]], [[4e6n\|4e6n]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Cthe_2768 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=203119 ~~Clostridium thermocellum ATCC 27405~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Cthe_2768 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=203119 CLOTH])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Polynucleotide_5'-hydroxyl-kinase Polynucleotide 5'-hydroxyl-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.78 2.7.1.78] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Polynucleotide_5'-hydroxyl-kinase Polynucleotide 5'-hydroxyl-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.78 2.7.1.78] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gp6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gp6 RCSB], [http://www.ebi.ac.uk/pdbsum/4gp6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gp6 OCA], [http://pdbe.org/4gp6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gp6 RCSB], [http://www.ebi.ac.uk/pdbsum/4gp6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gp6 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4gp6" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Clostridium thermocellum atcc 27405~~]]	+	[[Category: Cloth]]
	[[Category: Polynucleotide 5'-hydroxyl-kinase]]		[[Category: Polynucleotide 5'-hydroxyl-kinase]]
	[[Category: Das, U]]		[[Category: Das, U]]

OCA at 09:16, 10 December 2014

2014-12-10T09:16:24Z

←Older revision		Revision as of 09:16, 10 December 2014
Line 1:		Line 1:
-	[[~~Image:~~4gp6.~~png~~\|~~left~~\|~~200px~~]]	+	==Polynucleotide kinase==
		+	<StructureSection load='4gp6' size='340' side='right' caption='[[4gp6]], [[Resolution\|resolution]] 2.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4gp6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_thermocellum_atcc_27405 Clostridium thermocellum atcc 27405]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GP6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GP6 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4gp7\|4gp7]], [[3ty5\|3ty5]], [[3ty8\|3ty8]], [[3ty9\|3ty9]], [[4drf\|4drf]], [[4e6n\|4e6n]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Cthe_2768 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=203119 Clostridium thermocellum ATCC 27405])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Polynucleotide_5'-hydroxyl-kinase Polynucleotide 5'-hydroxyl-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.78 2.7.1.78] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gp6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gp6 RCSB], [http://www.ebi.ac.uk/pdbsum/4gp6 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Pnkp is the end-healing and end-sealing component of an RNA repair system present in diverse bacteria from many phyla. Pnkp is composed of three catalytic modules: an N-terminal polynucleotide 5'-kinase, a central 2',3' phosphatase, and a C-terminal ligase. Here we report the crystal structure of the kinase domain of Clostridium thermocellum Pnkp bound to ATPMg(2+) (substrate complex) and ADPMg(2+) (product complex). The protein consists of a core P-loop phosphotransferase fold embellished by a distinctive homodimerization module composed of secondary structure elements derived from the N and C termini of the kinase domain. ATP is bound within a crescent-shaped groove formed by the P-loop ((15)GSSGSGKST(23)) and an overlying helix-loop-helix "lid." The alpha and beta phosphates are engaged by a network of hydrogen bonds from Thr23 and the P-loop main-chain amides; the gamma phosphate is anchored by the lid residues Arg120 and Arg123. The P-loop lysine (Lys21) and the catalytic Mg(2+) bridge the ATP beta and gamma phosphates. The P-loop serine (Ser22) is the sole enzymic constituent of the octahedral metal coordination complex. Structure-guided mutational analysis underscored the essential contributions of Lys21 and Ser22 in the ATP donor site and Asp38 and Arg41 in the phosphoacceptor site. Our studies suggest a catalytic mechanism whereby Asp38 (as general base) activates the polynucleotide 5'-OH for its nucleophilic attack on the gamma phosphorus and Lys21 and Mg(2+) stabilize the transition state.

-	~~{{STRUCTURE_4gp6\| PDB=4gp6 \| SCENE= }}~~	+	Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system.,Wang LK, Das U, Smith P, Shuman S RNA. 2012 Nov 1. PMID:23118415<ref>PMID:23118415</ref>

-	~~===Polynucleotide kinase===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_23118415}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[4gp6]] is a 2 chain structure with sequence from [http:~~//en.wikipedia.org/wiki/Clostridium_thermocellum_atcc_27405 Clostridium thermocellum atcc 27405]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GP6 OCA].	+	</StructureSection>
	[[Category: Clostridium thermocellum atcc 27405]]		[[Category: Clostridium thermocellum atcc 27405]]
	[[Category: Polynucleotide 5'-hydroxyl-kinase]]		[[Category: Polynucleotide 5'-hydroxyl-kinase]]
-	[[Category: Das, U.]]	+	[[Category: Das, U]]
-	[[Category: Shuman, S.]]	+	[[Category: Shuman, S]]
-	[[Category: Smith, P.]]	+	[[Category: Smith, P]]
-	[[Category: Wang, L K.]]	+	[[Category: Wang, L K]]
	[[Category: Polynucleotide kinase phosphatase]]		[[Category: Polynucleotide kinase phosphatase]]
	[[Category: Rna repair]]		[[Category: Rna repair]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 09:53, 5 December 2012

2012-12-05T09:53:25Z

←Older revision		Revision as of 09:53, 5 December 2012
Line 1:		Line 1:
-	[[Image:4gp6.~~jpg~~\|left\|200px]]	+	[[Image:4gp6.png\|left\|200px]]

	{{STRUCTURE_4gp6\| PDB=4gp6 \| SCENE= }}		{{STRUCTURE_4gp6\| PDB=4gp6 \| SCENE= }}
Line 5:		Line 5:
	===Polynucleotide kinase===		===Polynucleotide kinase===

		+	{{ABSTRACT_PUBMED_23118415}}

	==About this Structure==		==About this Structure==

OCA at 06:41, 14 November 2012

2012-11-14T06:41:05Z

←Older revision		Revision as of 06:41, 14 November 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4gp6.jpg\|left\|200px]]

-	~~The entry~~ 4gp6 ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_4gp6\| PDB=4gp6 \| SCENE= }}

-	~~Authors: Wang, L.K., Das, U., Smith, P., Shuman, S.~~	+	===Polynucleotide kinase===

-	~~Description~~: Polynucleotide kinase	+
		+	==About this Structure==
		+	[[4gp6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_thermocellum_atcc_27405 Clostridium thermocellum atcc 27405]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GP6 OCA].
		+	[[Category: Clostridium thermocellum atcc 27405]]
		+	[[Category: Polynucleotide 5'-hydroxyl-kinase]]
		+	[[Category: Das, U.]]
		+	[[Category: Shuman, S.]]
		+	[[Category: Smith, P.]]
		+	[[Category: Wang, L K.]]
		+	[[Category: Polynucleotide kinase phosphatase]]
		+	[[Category: Rna repair]]
		+	[[Category: Transferase]]

OCA at 04:52, 12 September 2012

2012-09-12T04:52:07Z

←Older revision		Revision as of 04:52, 12 September 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4gp6 is ON HOLD	+	The entry 4gp6 is ON HOLD until Paper Publication

	Authors: Wang, L.K., Das, U., Smith, P., Shuman, S.		Authors: Wang, L.K., Das, U., Smith, P., Shuman, S.

	Description: Polynucleotide kinase		Description: Polynucleotide kinase

OCA at 04:55, 5 September 2012

2012-09-05T04:55:46Z

←Older revision		Revision as of 04:55, 5 September 2012
Line 5:		Line 5:
	Authors: Wang, L.K., Das, U., Smith, P., Shuman, S.		Authors: Wang, L.K., Das, U., Smith, P., Shuman, S.

-	Description: ~~Structure of Cth~~ Polynucleotide kinase ~~phosphatase~~	+	Description: Polynucleotide kinase

OCA: Protected "4gp6" [edit=sysop:move=sysop]

2012-08-29T04:49:35Z

Protected "4gp6" [edit=sysop:move=sysop]

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Revision as of 04:49, 29 August 2012

OCA: New page: '''Unreleased structure''' The entry 4gp6 is ON HOLD Authors: Wang, L.K., Das, U., Smith, P., Shuman, S. Description: Structure of Cth Polynucleotide kinase phosphatase

2012-08-29T04:49:34Z

New page: '''Unreleased structure''' The entry 4gp6 is ON HOLD Authors: Wang, L.K., Das, U., Smith, P., Shuman, S. Description: Structure of Cth Polynucleotide kinase phosphatase

New page

'''Unreleased structure'''

The entry 4gp6 is ON HOLD

Authors: Wang, L.K., Das, U., Smith, P., Shuman, S.

Description: Structure of Cth Polynucleotide kinase phosphatase