4h3s - Revision history

OCA at 14:59, 20 September 2023

2023-09-20T14:59:52Z

←Older revision		Revision as of 14:59, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4h3s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H3S FirstGlance]. <br>		<table><tr><td colspan='2'>[[4h3s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H3S FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.15Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3s OCA], [https://pdbe.org/4h3s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h3s RCSB], [https://www.ebi.ac.uk/pdbsum/4h3s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h3s ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3s OCA], [https://pdbe.org/4h3s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h3s RCSB], [https://www.ebi.ac.uk/pdbsum/4h3s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h3s ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:57, 3 November 2022

2022-11-03T07:57:56Z

←Older revision		Revision as of 07:57, 3 November 2022
Line 1:		Line 1:

	==The Structure of Glutaminyl-tRNA Synthetase from Saccharomyces Cerevisiae==		==The Structure of Glutaminyl-tRNA Synthetase from Saccharomyces Cerevisiae==
-	<StructureSection load='4h3s' size='340' side='right' caption='[[4h3s]], [[Resolution\|resolution]] 2.15Å' scene=''>	+	<StructureSection load='4h3s' size='340' side='right'caption='[[4h3s]], [[Resolution\|resolution]] 2.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4h3s]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Baker's_yeast Baker's yeast~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3S OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4H3S FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4h3s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H3S FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3tl4\|3tl4]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3s OCA], [https://pdbe.org/4h3s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h3s RCSB], [https://www.ebi.ac.uk/pdbsum/4h3s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h3s ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GLN4, O3601, YOR168W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamine--tRNA_ligase Glutamine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.18 6.1.1.18] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4h3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3s OCA], [~~http~~://pdbe.org/4h3s PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4h3s RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4h3s PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4h3s ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/SYQ_YEAST SYQ_YEAST]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4h3s" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4h3s" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Aminoacyl tRNA synthetase 3D structures\|Aminoacyl tRNA synthetase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Baker's yeast~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Glutamine--tRNA ligase~~]]	+	[[Category: Saccharomyces cerevisiae S288C]]
-	[[Category: Grant~~, T D~~]]	+	[[Category: Grant TD]]
-	[[Category: Snell~~, E H]]~~	+	[[Category: Snell EH]]
-	~~[[Category: Appended domain]]~~	+
-	~~[[Category: Beta barrel anticodon binding domain]]~~	+
-	~~[[Category: Ligase]]~~	+
-	~~[[Category: Pseudo zinc finger motif]]~~	+
-	~~[[Category: Rossmann fold]]~~	+
-	~~[[Category: Trna synthetase~~]]	+

OCA at 13:48, 11 August 2016

2016-08-11T13:48:30Z

←Older revision		Revision as of 13:48, 11 August 2016
Line 1:		Line 1:
		+
	==The Structure of Glutaminyl-tRNA Synthetase from Saccharomyces Cerevisiae==		==The Structure of Glutaminyl-tRNA Synthetase from Saccharomyces Cerevisiae==
	<StructureSection load='4h3s' size='340' side='right' caption='[[4h3s]], [[Resolution\|resolution]] 2.15Å' scene=''>		<StructureSection load='4h3s' size='340' side='right' caption='[[4h3s]], [[Resolution\|resolution]] 2.15Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GLN4, O3601, YOR168W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GLN4, O3601, YOR168W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamine--tRNA_ligase Glutamine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.18 6.1.1.18] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamine--tRNA_ligase Glutamine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.18 6.1.1.18] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h3s RCSB], [http://www.ebi.ac.uk/pdbsum/4h3s PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3s OCA], [http://pdbe.org/4h3s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4h3s RCSB], [http://www.ebi.ac.uk/pdbsum/4h3s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4h3s ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4h3s" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:06, 26 November 2014

2014-11-26T06:06:08Z

←Older revision		Revision as of 06:06, 26 November 2014
Line 2:		Line 2:
	<StructureSection load='4h3s' size='340' side='right' caption='[[4h3s]], [[Resolution\|resolution]] 2.15Å' scene=''>		<StructureSection load='4h3s' size='340' side='right' caption='[[4h3s]], [[Resolution\|resolution]] 2.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4h3s]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H3S FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4h3s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H3S FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3tl4\|3tl4]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3tl4\|3tl4]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GLN4, O3601, YOR168W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamine--tRNA_ligase Glutamine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.18 6.1.1.18] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamine--tRNA_ligase Glutamine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.18 6.1.1.18] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h3s RCSB], [http://www.ebi.ac.uk/pdbsum/4h3s PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h3s RCSB], [http://www.ebi.ac.uk/pdbsum/4h3s PDBsum]</span></td></tr>
Line 20:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Baker's yeast]]
	[[Category: Glutamine--tRNA ligase]]		[[Category: Glutamine--tRNA ligase]]
	[[Category: Grant, T D]]		[[Category: Grant, T D]]

OCA at 07:35, 12 November 2014

2014-11-12T07:35:04Z

←Older revision		Revision as of 07:35, 12 November 2014
Line 2:		Line 2:
	<StructureSection load='4h3s' size='340' side='right' caption='[[4h3s]], [[Resolution\|resolution]] 2.15Å' scene=''>		<StructureSection load='4h3s' size='340' side='right' caption='[[4h3s]], [[Resolution\|resolution]] 2.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4h3s]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H3S FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4h3s]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H3S FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3tl4\|3tl4]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3tl4\|3tl4]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GLN4, O3601, YOR168W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Saccharomyces cerevisiae S288c])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamine--tRNA_ligase Glutamine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.18 6.1.1.18] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamine--tRNA_ligase Glutamine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.18 6.1.1.18] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h3s RCSB], [http://www.ebi.ac.uk/pdbsum/4h3s PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h3s RCSB], [http://www.ebi.ac.uk/pdbsum/4h3s PDBsum]</span></td></tr>
Line 22:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Glutamine--tRNA ligase]]		[[Category: Glutamine--tRNA ligase]]
-	~~[[Category: Saccharomyces cerevisiae s288c]]~~	+	[[Category: Grant, T D]]
-	[[Category: Grant, T D.]]	+	[[Category: Snell, E H]]
-	[[Category: Snell, E H.]]	+
	[[Category: Appended domain]]		[[Category: Appended domain]]
	[[Category: Beta barrel anticodon binding domain]]		[[Category: Beta barrel anticodon binding domain]]

OCA at 14:03, 3 November 2014

2014-11-03T14:03:53Z

←Older revision		Revision as of 14:03, 3 November 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4h3s\| PDB=4h3s \| SCENE= }}~~	+	==The Structure of Glutaminyl-tRNA Synthetase from Saccharomyces Cerevisiae==
-	===The Structure of Glutaminyl-tRNA Synthetase from Saccharomyces Cerevisiae===	+	<StructureSection load='4h3s' size='340' side='right' caption='[[4h3s]], [[Resolution\|resolution]] 2.15Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23583912}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4h3s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H3S FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3tl4\|3tl4]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GLN4, O3601, YOR168W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Saccharomyces cerevisiae S288c])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamine--tRNA_ligase Glutamine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.18 6.1.1.18] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h3s RCSB], [http://www.ebi.ac.uk/pdbsum/4h3s PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Eukaryotic glutaminyl-tRNA synthetase (GlnRS) contains an appended N-terminal domain (NTD) whose precise function is unknown. Although GlnRS structures from two prokaryotic species are known, no eukaryotic GlnRS structure has been reported. Here we present the first crystallographic structure of yeast GlnRS, finding that the structure of the C-terminal domain is highly similar to Escherichia coli GlnRS but that 214 residues, including the NTD, are crystallographically disordered. We present a model of the full-length enzyme in solution, using the structures of the C-terminal domain, and the isolated NTD, with small-angle X-ray scattering data of the full-length molecule. We proceed to model the enzyme bound to tRNA, using the crystallographic structures of GatCAB and GlnRS-tRNA complex from bacteria. We contrast the tRNA-bound model with the tRNA-free solution state and perform molecular dynamics on the full-length GlnRS-tRNA complex, which suggests that tRNA binding involves the motion of a conserved hinge in the NTD.

-	~~==About this~~ Structure==	+	The Structure of Yeast Glutaminyl-tRNA Synthetase and Modeling of Its Interaction with tRNA.,Grant TD, Luft JR, Wolfley JR, Snell ME, Tsuruta H, Corretore S, Quartley E, Phizicky EM, Grayhack EJ, Snell EH J Mol Biol. 2013 Apr 10. pii: S0022-2836(13)00211-8. doi:, 10.1016/j.jmb.2013.03.043. PMID:23583912<ref>PMID:23583912</ref>
-	~~[[4h3s]] is a 1 chain structure~~ with ~~sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.~~il/oca-bin/ocashort?id=4H3S OCA]~~.	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:023583912</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Glutamine--tRNA ligase]]		[[Category: Glutamine--tRNA ligase]]
	[[Category: Saccharomyces cerevisiae s288c]]		[[Category: Saccharomyces cerevisiae s288c]]
Line 16:		Line 29:
	[[Category: Ligase]]		[[Category: Ligase]]
	[[Category: Pseudo zinc finger motif]]		[[Category: Pseudo zinc finger motif]]
-	[[Category: ~~Rossman~~ fold]]	+	[[Category: Rossmann fold]]
	[[Category: Trna synthetase]]		[[Category: Trna synthetase]]

OCA at 03:43, 1 August 2013

2013-08-01T03:43:36Z

←Older revision		Revision as of 03:43, 1 August 2013
Line 5:		Line 5:
	==About this Structure==		==About this Structure==
	[[4h3s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3S OCA].		[[4h3s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3S OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:023583912</ref><references group="xtra"/><references/>
	[[Category: Glutamine--tRNA ligase]]		[[Category: Glutamine--tRNA ligase]]
	[[Category: Saccharomyces cerevisiae s288c]]		[[Category: Saccharomyces cerevisiae s288c]]

OCA at 06:43, 2 May 2013

2013-05-02T06:43:53Z

←Older revision		Revision as of 06:43, 2 May 2013
Line 1:		Line 1:
	{{STRUCTURE_4h3s\| PDB=4h3s \| SCENE= }}		{{STRUCTURE_4h3s\| PDB=4h3s \| SCENE= }}
	===The Structure of Glutaminyl-tRNA Synthetase from Saccharomyces Cerevisiae===		===The Structure of Glutaminyl-tRNA Synthetase from Saccharomyces Cerevisiae===
		+	{{ABSTRACT_PUBMED_23583912}}

	==About this Structure==		==About this Structure==

OCA at 11:28, 24 April 2013

2013-04-24T11:28:57Z

←Older revision		Revision as of 11:28, 24 April 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4h3s\| PDB=4h3s \| SCENE= }}
		+	===The Structure of Glutaminyl-tRNA Synthetase from Saccharomyces Cerevisiae===

-	~~The entry~~ 4h3s is ~~ON HOLD~~	+	==About this Structure==
-		+	[[4h3s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3S OCA].
-	~~Authors~~: ~~Snell, E~~.H., Grant, T.D.	+	[[Category: Glutamine--tRNA ligase]]
-		+	[[Category: Saccharomyces cerevisiae s288c]]
-	~~Description~~: ~~The Structure of Glutaminyl-tRNA Synthetase from Saccharomyces Cerevisiae~~	+	[[Category: Grant, T D.]]
		+	[[Category: Snell, E H.]]
		+	[[Category: Appended domain]]
		+	[[Category: Beta barrel anticodon binding domain]]
		+	[[Category: Ligase]]
		+	[[Category: Pseudo zinc finger motif]]
		+	[[Category: Rossman fold]]
		+	[[Category: Trna synthetase]]

OCA at 19:46, 17 April 2013

2013-04-17T19:46:44Z

←Older revision		Revision as of 19:46, 17 April 2013
Line 5:		Line 5:
	Authors: Snell, E.H., Grant, T.D.		Authors: Snell, E.H., Grant, T.D.

-	Description: The Structure ~~and Binding Mechanism~~ of ~~Eukaryotic~~ Glutaminyl-tRNA Synthetase~~-tRNAgln Complex~~	+	Description: The Structure of Glutaminyl-tRNA Synthetase from Saccharomyces Cerevisiae