4h9o - Revision history

OCA at 11:36, 1 March 2024

2024-03-01T11:36:08Z

←Older revision		Revision as of 11:36, 1 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4h9o]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H9O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H9O FirstGlance]. <br>		<table><tr><td colspan='2'>[[4h9o]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H9O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H9O FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.053Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h9o OCA], [https://pdbe.org/4h9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h9o RCSB], [https://www.ebi.ac.uk/pdbsum/4h9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h9o ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h9o OCA], [https://pdbe.org/4h9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h9o RCSB], [https://www.ebi.ac.uk/pdbsum/4h9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h9o ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:06, 3 November 2022

2022-11-03T08:06:14Z

←Older revision		Revision as of 08:06, 3 November 2022
Line 1:		Line 1:

	==Complex structure 2 of DAXX/H3.3(sub5,G90M)/H4==		==Complex structure 2 of DAXX/H3.3(sub5,G90M)/H4==
-	<StructureSection load='4h9o' size='340' side='right' caption='[[4h9o]], [[Resolution\|resolution]] 2.05Å' scene=''>	+	<StructureSection load='4h9o' size='340' side='right'caption='[[4h9o]], [[Resolution\|resolution]] 2.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4h9o]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H9O OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4H9O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4h9o]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H9O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H9O FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4h9n\|4h9n]], [[4h9p\|4h9p]], [[4h9q\|4h9q]], [[4h9r\|4h9r]], [[4h9s\|4h9s]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h9o OCA], [https://pdbe.org/4h9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h9o RCSB], [https://www.ebi.ac.uk/pdbsum/4h9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h9o ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">H3F3A, H3.3A, H3F3, PP781, H3F3B, H3.3B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), DAXX, BING2, DAP6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4h9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h9o OCA], [~~http~~://pdbe.org/4h9o PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4h9o RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4h9o PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4h9o ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~DAXX_HUMAN DAXX_HUMAN~~]] Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 ligase MDM2 ubiquitination activity. Under non-stress condition, in association with the deubiquitinating USP7, prevents MDM2 self-ubiquitination and enhances the intrinsic E3 ligase activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and subsequent proteasomal degradation. Upon DNA damage, its association with MDM2 and USP7 is disrupted, resulting in increased MDM2 autoubiquitination and consequently, MDM2 degradation, which leads to TP53 stabilization. Proposed to mediate activation of the JNK pathway and apoptosis via MAP3K5 in response to signaling from TNFRSF6 and TGFBR2. Interaction with HSPB1/HSP27 may prevent interaction with TNFRSF6 and MAP3K5 and block DAXX-mediated apoptosis. In contrast, in lymphoid cells JNC activation and TNFRSF6-mediated apoptosis may not involve DAXX. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Down-regulates basal and activated transcription. Seems to act as a transcriptional corepressor and inhibits PAX3 and ETS1 through direct protein-protein interaction. Modulates PAX5 activity. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively.<ref>PMID:12140263</ref> <ref>PMID:15364927</ref> <ref>PMID:17081986</ref> <ref>PMID:16845383</ref>	+	[https://www.uniprot.org/uniprot/H33_HUMAN H33_HUMAN]

	==See Also==		==See Also==
-	*[[Death-associated protein\|Death-associated protein]]	+	*[[Death-associated protein 3D structures\|Death-associated protein 3D structures]]
-	*[[Histone\|Histone]]	+	*[[Histone 3D structures\|Histone 3D structures]]
-	~~== References ==~~	+
-	~~<references/>~~	+
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: Allis~~, D C~~]]	+	[[Category: Large Structures]]
-	[[Category: Chin~~, J W~~]]	+	[[Category: Allis DC]]
-	[[Category: Elsasser~~, S J~~]]	+	[[Category: Chin JW]]
-	[[Category: Huang, H]]	+	[[Category: Elsasser SJ]]
-	[[Category: Lewis~~, P W~~]]	+	[[Category: Huang H]]
-	[[Category: Patel~~, D J]]~~	+	[[Category: Lewis PW]]
-	~~[[Category: Dna binding protein-apoptosis complex]]~~	+	[[Category: Patel DJ]]
-	~~[[Category: Histone chaperone~~]]	+

OCA at 00:37, 5 August 2016

2016-08-05T00:37:27Z

←Older revision		Revision as of 00:37, 5 August 2016
Line 1:		Line 1:
		+
	==Complex structure 2 of DAXX/H3.3(sub5,G90M)/H4==		==Complex structure 2 of DAXX/H3.3(sub5,G90M)/H4==
	<StructureSection load='4h9o' size='340' side='right' caption='[[4h9o]], [[Resolution\|resolution]] 2.05Å' scene=''>		<StructureSection load='4h9o' size='340' side='right' caption='[[4h9o]], [[Resolution\|resolution]] 2.05Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4h9n\|4h9n]], [[4h9p\|4h9p]], [[4h9q\|4h9q]], [[4h9r\|4h9r]], [[4h9s\|4h9s]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4h9n\|4h9n]], [[4h9p\|4h9p]], [[4h9q\|4h9q]], [[4h9r\|4h9r]], [[4h9s\|4h9s]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">H3F3A, H3.3A, H3F3, PP781, H3F3B, H3.3B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), DAXX, BING2, DAP6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">H3F3A, H3.3A, H3F3, PP781, H3F3B, H3.3B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), DAXX, BING2, DAP6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h9o RCSB], [http://www.ebi.ac.uk/pdbsum/4h9o PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h9o OCA], [http://pdbe.org/4h9o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4h9o RCSB], [http://www.ebi.ac.uk/pdbsum/4h9o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4h9o ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 21:14, 24 December 2014

2014-12-24T21:14:58Z

←Older revision		Revision as of 21:14, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4h9o]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H9O FirstGlance]. <br>		<table><tr><td colspan='2'>[[4h9o]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H9O FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4h9n\|4h9n]], [[4h9p\|4h9p]], [[4h9q\|4h9q]], [[4h9r\|4h9r]], [[4h9s\|4h9s]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4h9n\|4h9n]], [[4h9p\|4h9p]], [[4h9q\|4h9q]], [[4h9r\|4h9r]], [[4h9s\|4h9s]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">H3F3A, H3.3A, H3F3, PP781, H3F3B, H3.3B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), DAXX, BING2, DAP6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">H3F3A, H3.3A, H3F3, PP781, H3F3B, H3.3B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), DAXX, BING2, DAP6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h9o RCSB], [http://www.ebi.ac.uk/pdbsum/4h9o PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h9o RCSB], [http://www.ebi.ac.uk/pdbsum/4h9o PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DAXX_HUMAN DAXX_HUMAN]] Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 ligase MDM2 ubiquitination activity. Under non-stress condition, in association with the deubiquitinating USP7, prevents MDM2 self-ubiquitination and enhances the intrinsic E3 ligase activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and subsequent proteasomal degradation. Upon DNA damage, its association with MDM2 and USP7 is disrupted, resulting in increased MDM2 autoubiquitination and consequently, MDM2 degradation, which leads to TP53 stabilization. Proposed to mediate activation of the JNK pathway and apoptosis via MAP3K5 in response to signaling from TNFRSF6 and TGFBR2. Interaction with HSPB1/HSP27 may prevent interaction with TNFRSF6 and MAP3K5 and block DAXX-mediated apoptosis. In contrast, in lymphoid cells JNC activation and TNFRSF6-mediated apoptosis may not involve DAXX. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Down-regulates basal and activated transcription. Seems to act as a transcriptional corepressor and inhibits PAX3 and ETS1 through direct protein-protein interaction. Modulates PAX5 activity. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively.<ref>PMID:12140263</ref> <ref>PMID:15364927</ref> <ref>PMID:17081986</ref> <ref>PMID:16845383</ref>

	==See Also==		==See Also==
	*[[Death-associated protein\|Death-associated protein]]		*[[Death-associated protein\|Death-associated protein]]
	*[[Histone\|Histone]]		*[[Histone\|Histone]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
-	[[Category: Allis, D C.]]	+	[[Category: Allis, D C]]
-	[[Category: Chin, J W.]]	+	[[Category: Chin, J W]]
-	[[Category: Elsasser, S J.]]	+	[[Category: Elsasser, S J]]
-	[[Category: Huang, H.]]	+	[[Category: Huang, H]]
-	[[Category: Lewis, P W.]]	+	[[Category: Lewis, P W]]
-	[[Category: Patel, D J.]]	+	[[Category: Patel, D J]]
	[[Category: Dna binding protein-apoptosis complex]]		[[Category: Dna binding protein-apoptosis complex]]
	[[Category: Histone chaperone]]		[[Category: Histone chaperone]]

OCA at 10:45, 16 July 2014

2014-07-16T10:45:08Z

←Older revision		Revision as of 10:45, 16 July 2014
Line 1:		Line 1:
-	[[~~Image:~~4h9o.~~jpg~~\|~~left~~\|~~200px~~]]	+	==Complex structure 2 of DAXX/H3.3(sub5,G90M)/H4==
		+	<StructureSection load='4h9o' size='340' side='right' caption='[[4h9o]], [[Resolution\|resolution]] 2.05Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4h9o]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H9O FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4h9n\|4h9n]], [[4h9p\|4h9p]], [[4h9q\|4h9q]], [[4h9r\|4h9r]], [[4h9s\|4h9s]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">H3F3A, H3.3A, H3F3, PP781, H3F3B, H3.3B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), DAXX, BING2, DAP6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h9o RCSB], [http://www.ebi.ac.uk/pdbsum/4h9o PDBsum]</span></td></tr>
		+	<table>

-	~~{{STRUCTURE_4h9o\| PDB~~=~~4h9o \| SCENE= }}~~	+	==See Also==
-		+	*[[Death-associated protein\|Death-associated protein]]
-	~~===Complex structure 2 of DAXX/H3.3(sub5,G90M)/H4~~===	+	*[[Histone\|Histone]]
-		+	__TOC__
-		+	</StructureSection>
-	~~==About this Structure==~~	+	[[Category: Human]]
-	[[~~4h9o~~]] ~~is a 3 chain structure. Full crystallographic information is available from~~ [~~http~~:~~//oca.weizmann.ac.il/oca-bin/ocashort?id=4H9O OCA~~].	+
	[[Category: Allis, D C.]]		[[Category: Allis, D C.]]
	[[Category: Chin, J W.]]		[[Category: Chin, J W.]]

OCA at 07:31, 10 October 2012

2012-10-10T07:31:06Z

←Older revision		Revision as of 07:31, 10 October 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4h9o.jpg\|left\|200px]]

-	~~The entry~~ 4h9o ~~is ON HOLD~~	+	{{STRUCTURE_4h9o\| PDB=4h9o \| SCENE= }}

-	~~Authors: Elsasser, S.J~~., ~~Huang, H., Lewis, P.W., Chin, J.W., Allis, D.C., Patel, D.J.~~	+	===Complex structure 2 of DAXX/H3.3(sub5,G90M)/H4===

-	~~Description: Complex~~ structure ~~2 of DAXX~~/H3.~~3(sub5,G90M)~~/H4	+
		+	==About this Structure==
		+	[[4h9o]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H9O OCA].
		+	[[Category: Allis, D C.]]
		+	[[Category: Chin, J W.]]
		+	[[Category: Elsasser, S J.]]
		+	[[Category: Huang, H.]]
		+	[[Category: Lewis, P W.]]
		+	[[Category: Patel, D J.]]
		+	[[Category: Dna binding protein-apoptosis complex]]
		+	[[Category: Histone chaperone]]

OCA: Protected "4h9o" [edit=sysop:move=sysop]

2012-10-03T05:50:45Z

Protected "4h9o" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:50, 3 October 2012

OCA: New page: '''Unreleased structure''' The entry 4h9o is ON HOLD Authors: Elsasser, S.J., Huang, H., Lewis, P.W., Chin, J.W., Allis, D.C., Patel, D.J. Description: Complex structure 2 of DAXX/H3.3...

2012-10-03T05:50:44Z

New page: '''Unreleased structure''' The entry 4h9o is ON HOLD Authors: Elsasser, S.J., Huang, H., Lewis, P.W., Chin, J.W., Allis, D.C., Patel, D.J. Description: Complex structure 2 of DAXX/H3.3...

New page

'''Unreleased structure'''

The entry 4h9o is ON HOLD

Authors: Elsasser, S.J., Huang, H., Lewis, P.W., Chin, J.W., Allis, D.C., Patel, D.J.

Description: Complex structure 2 of DAXX/H3.3(sub5,G90M)/H4