4hrv - Revision history

OCA at 08:09, 9 November 2022

2022-11-09T08:09:04Z

←Older revision		Revision as of 08:09, 9 November 2022
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	==Crystal Structure of Lipoprotein GNA1162 from Neisseria meningitidis==		==Crystal Structure of Lipoprotein GNA1162 from Neisseria meningitidis==
-	<StructureSection load='4hrv' size='340' side='right' caption='[[4hrv]], [[Resolution\|resolution]] 1.89Å' scene=''>	+	<StructureSection load='4hrv' size='340' side='right'caption='[[4hrv]], [[Resolution\|resolution]] 1.89Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4hrv]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"diplokokkus_intracellularis_meningitidis"_(sic)_weichselbaum_1887 "diplokokkus intracellularis~~ meningitidis~~" (sic) weichselbaum 1887~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HRV OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4HRV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4hrv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_meningitidis Neisseria meningitidis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HRV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HRV FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gna1162 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=487 "Diplokokkus intracellularis meningitidis" (sic) Weichselbaum 1887])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hrv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hrv OCA], [https://pdbe.org/4hrv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hrv RCSB], [https://www.ebi.ac.uk/pdbsum/4hrv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hrv ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4hrv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hrv OCA], [~~http~~://pdbe.org/4hrv PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4hrv RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4hrv PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4hrv ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q7BMM3_NEIME Q7BMM3_NEIME]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Cai, X~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Lin, Z~~]]	+	[[Category: Neisseria meningitidis]]
-	[[Category: ~~Shen, Y~~]]	+	[[Category: Cai X]]
-	[[Category: ~~Duf799~~]]	+	[[Category: Lin Z]]
-	[[Category: ~~Lipid binding protein~~]]	+	[[Category: Shen Y]]

OCA at 12:08, 5 August 2016

2016-08-05T12:08:28Z

←Older revision		Revision as of 12:08, 5 August 2016
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		+
	==Crystal Structure of Lipoprotein GNA1162 from Neisseria meningitidis==		==Crystal Structure of Lipoprotein GNA1162 from Neisseria meningitidis==
	<StructureSection load='4hrv' size='340' side='right' caption='[[4hrv]], [[Resolution\|resolution]] 1.89Å' scene=''>		<StructureSection load='4hrv' size='340' side='right' caption='[[4hrv]], [[Resolution\|resolution]] 1.89Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4hrv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Neisseria_meningitidis Neisseria~~ meningitidis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HRV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HRV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4hrv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"diplokokkus_intracellularis_meningitidis"_(sic)_weichselbaum_1887 "diplokokkus intracellularis meningitidis" (sic) weichselbaum 1887]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HRV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HRV FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gna1162 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=487 ~~Neisseria~~ meningitidis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gna1162 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=487 "Diplokokkus intracellularis meningitidis" (sic) Weichselbaum 1887])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hrv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hrv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hrv RCSB], [http://www.ebi.ac.uk/pdbsum/4hrv PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hrv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hrv OCA], [http://pdbe.org/4hrv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hrv RCSB], [http://www.ebi.ac.uk/pdbsum/4hrv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hrv ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4hrv" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Neisseria meningitidis]]
	[[Category: Cai, X]]		[[Category: Cai, X]]
	[[Category: Lin, Z]]		[[Category: Lin, Z]]

OCA at 12:29, 21 December 2014

2014-12-21T12:29:25Z

←Older revision		Revision as of 12:29, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4hrv\| PDB~~=4hrv \| ~~SCENE~~= }}	+	==Crystal Structure of Lipoprotein GNA1162 from Neisseria meningitidis==
-	===~~Crystal Structure of Lipoprotein GNA1162~~ from Neisseria meningitidis===	+	<StructureSection load='4hrv' size='340' side='right' caption='[[4hrv]], [[Resolution\|resolution]] 1.89Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23545639}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4hrv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis Neisseria meningitidis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HRV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HRV FirstGlance]. <br>
		+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gna1162 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=487 Neisseria meningitidis])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hrv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hrv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hrv RCSB], [http://www.ebi.ac.uk/pdbsum/4hrv PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	GNA1162, a predicted lipoprotein from Neisseria meningitidis, is a potential candidate for a universal vaccine against meningococcal disease caused by N. meningitidis serogroup B. Here, the crystal structure of GNA1162 at 1.89 A resolution determined by single-wavelength anomalous dispersion (SAD) is reported. The structure of GNA1162 appears to be a dimer in the crystallographic asymmetric unit as well as in solution. The overall structure of the dimer indicates that each monomer inserts its C-terminal alpha5 helix into the hydrophobic groove of the other molecule. Moreover, the beta4 strands of each monomer lie antiparallel to each other and interact through multiple main-chain hydrogen bonds. Through structural comparisons and operon predictions, it is hypothesized that GNA1162 is part of a transport system and assists in transport and reassembly. The crystal structure of GNA1162 sheds light on its possible function and provides potentially valuable information for the design of a vaccine against meningococcal disease.

-	~~==About this~~ Structure==	+	Structure of Neisseria meningitidis lipoprotein GNA1162.,Cai X, Lu J, Wu Z, Yang C, Xu H, Lin Z, Shen Y Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Apr 1;69(Pt 4):362-8. doi:, 10.1107/S1744309113004417. Epub 2013 Mar 28. PMID:23545639<ref>PMID:23545639</ref>
-	~~[[4hrv]] is a 2 chain structure with sequence from [http~~:~~//en~~.~~wikipedia~~.~~org/wiki~~/~~Neisseria_meningitidis Neisseria meningitidis]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id~~=~~4HRV OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Neisseria meningitidis]]		[[Category: Neisseria meningitidis]]
-	[[Category: Cai, X.]]	+	[[Category: Cai, X]]
-	[[Category: Lin, Z.]]	+	[[Category: Lin, Z]]
-	[[Category: Shen, Y.]]	+	[[Category: Shen, Y]]
	[[Category: Duf799]]		[[Category: Duf799]]
	[[Category: Lipid binding protein]]		[[Category: Lipid binding protein]]

OCA at 11:19, 24 April 2013

2013-04-24T11:19:23Z

←Older revision		Revision as of 11:19, 24 April 2013
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-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4hrv\| PDB=4hrv \| SCENE= }}
		+	===Crystal Structure of Lipoprotein GNA1162 from Neisseria meningitidis===
		+	{{ABSTRACT_PUBMED_23545639}}

-	~~The entry~~ 4hrv is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
-		+	[[4hrv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis Neisseria meningitidis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HRV OCA].
-	~~Authors~~: ~~Lin, Z.,~~ Cai, X., Shen, Y.	+	[[Category: Neisseria meningitidis]]
-		+	[[Category: Cai, X.]]
-	~~Description~~: ~~Crystal Structure of Lipoprotein GNA1162 from Neisseria meningitidis~~	+	[[Category: Lin, Z.]]
		+	[[Category: Shen, Y.]]
		+	[[Category: Duf799]]
		+	[[Category: Lipid binding protein]]

OCA at 12:23, 6 February 2013

2013-02-06T12:23:26Z

←Older revision		Revision as of 12:23, 6 February 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4hrv is ON HOLD	+	The entry 4hrv is ON HOLD until Paper Publication

	Authors: Lin, Z., Cai, X., Shen, Y.		Authors: Lin, Z., Cai, X., Shen, Y.

	Description: Crystal Structure of Lipoprotein GNA1162 from Neisseria meningitidis		Description: Crystal Structure of Lipoprotein GNA1162 from Neisseria meningitidis

OCA: Protected "4hrv" [edit=sysop:move=sysop]

2012-11-08T13:25:47Z

Protected "4hrv" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:25, 8 November 2012

OCA: New page: '''Unreleased structure''' The entry 4hrv is ON HOLD Authors: Lin, Z., Cai, X., Shen, Y. Description: Crystal Structure of Lipoprotein GNA1162 from Neisseria meningitidis

2012-11-08T13:25:46Z

New page: '''Unreleased structure''' The entry 4hrv is ON HOLD Authors: Lin, Z., Cai, X., Shen, Y. Description: Crystal Structure of Lipoprotein GNA1162 from Neisseria meningitidis

New page

'''Unreleased structure'''

The entry 4hrv is ON HOLD

Authors: Lin, Z., Cai, X., Shen, Y.

Description: Crystal Structure of Lipoprotein GNA1162 from Neisseria meningitidis