4hse - Revision history

OCA at 15:10, 20 September 2023

2023-09-20T15:10:25Z

←Older revision		Revision as of 15:10, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4hse]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HSE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HSE FirstGlance]. <br>		<table><tr><td colspan='2'>[[4hse]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HSE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HSE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GAI:GUANIDINE'>GAI</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GAI:GUANIDINE'>GAI</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hse FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hse OCA], [https://pdbe.org/4hse PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hse RCSB], [https://www.ebi.ac.uk/pdbsum/4hse PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hse ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hse FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hse OCA], [https://pdbe.org/4hse PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hse RCSB], [https://www.ebi.ac.uk/pdbsum/4hse PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hse ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:10, 9 November 2022

2022-11-09T08:10:09Z

←Older revision		Revision as of 08:10, 9 November 2022
Line 1:		Line 1:

	==Crystal structure of ClpB NBD1 in complex with guanidinium chloride and ADP==		==Crystal structure of ClpB NBD1 in complex with guanidinium chloride and ADP==
-	<StructureSection load='4hse' size='340' side='right' caption='[[4hse]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='4hse' size='340' side='right'caption='[[4hse]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4hse]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Thet8 Thet8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HSE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4HSE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4hse]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HSE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HSE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GAI:GUANIDINE'>GAI</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GAI:GUANIDINE'>GAI</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qvr\|1qvr]], [[1jbk\|1jbk]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hse FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hse OCA], [https://pdbe.org/4hse PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hse RCSB], [https://www.ebi.ac.uk/pdbsum/4hse PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hse ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">clpB, TTHA1487 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4hse FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hse OCA], [~~http~~://pdbe.org/4hse PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4hse RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4hse PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4hse ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/CLPB_THET8 CLPB_THET8]] Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.<ref>PMID:10377389</ref>	+	[https://www.uniprot.org/uniprot/CLPB_THET8 CLPB_THET8] Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.<ref>PMID:10377389</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 20:

	==See Also==		==See Also==
-	*[[Heat Shock ~~Proteins~~\|Heat Shock ~~Proteins~~]]	+	*[[Heat Shock Protein structures\|Heat Shock Protein structures]]
		+	*[[3D structures of ClpB\|3D structures of ClpB]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Thet8~~]]	+	[[Category: Large Structures]]
-	[[Category: Reinstein, J]]	+	[[Category: Thermus thermophilus HB8]]
-	[[Category: Schlichting, I]]	+	[[Category: Reinstein J]]
-	[[Category: Werbeck~~, N D~~]]	+	[[Category: Schlichting I]]
-	[[Category: Zeymer, C]]	+	[[Category: Werbeck ND]]
-	~~[[Category: Aaa+ protein]]~~	+	[[Category: Zeymer C]]
-	~~[[Category: Chaperone]]~~	+
-	~~[[Category: Molecular chaperone]]~~	+
-	~~[[Category: Nucleotide binding domain~~]]	+

OCA at 16:02, 5 August 2016

2016-08-05T16:02:01Z

←Older revision		Revision as of 16:02, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of ClpB NBD1 in complex with guanidinium chloride and ADP==		==Crystal structure of ClpB NBD1 in complex with guanidinium chloride and ADP==
	<StructureSection load='4hse' size='340' side='right' caption='[[4hse]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='4hse' size='340' side='right' caption='[[4hse]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4hse]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermus_thermophilus_hb8 Thermus thermophilus hb8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HSE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HSE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4hse]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HSE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HSE FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GAI:GUANIDINE'>GAI</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GAI:GUANIDINE'>GAI</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qvr\|1qvr]], [[1jbk\|1jbk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qvr\|1qvr]], [[1jbk\|1jbk]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">clpB, TTHA1487 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 ~~Thermus thermophilus HB8~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">clpB, TTHA1487 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hse FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hse OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hse RCSB], [http://www.ebi.ac.uk/pdbsum/4hse PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hse FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hse OCA], [http://pdbe.org/4hse PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hse RCSB], [http://www.ebi.ac.uk/pdbsum/4hse PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hse ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4hse" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Heat Shock Proteins\|Heat Shock Proteins]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Thermus thermophilus hb8~~]]	+	[[Category: Thet8]]
	[[Category: Reinstein, J]]		[[Category: Reinstein, J]]
	[[Category: Schlichting, I]]		[[Category: Schlichting, I]]

OCA at 03:49, 25 December 2014

2014-12-25T03:49:12Z

←Older revision		Revision as of 03:49, 25 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4hse\| PDB=4hse \| SCENE= }}~~	+	==Crystal structure of ClpB NBD1 in complex with guanidinium chloride and ADP==
-	===Crystal structure of ClpB NBD1 in complex with guanidinium chloride and ADP===	+	<StructureSection load='4hse' size='340' side='right' caption='[[4hse]], [[Resolution\|resolution]] 2.20Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23341453}}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4hse]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HSE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HSE FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GAI:GUANIDINE'>GAI</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qvr\|1qvr]], [[1jbk\|1jbk]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">clpB, TTHA1487 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 Thermus thermophilus HB8])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hse FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hse OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hse RCSB], [http://www.ebi.ac.uk/pdbsum/4hse PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/CLPB_THET8 CLPB_THET8]] Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.<ref>PMID:10377389</ref>		[[http://www.uniprot.org/uniprot/CLPB_THET8 CLPB_THET8]] Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.<ref>PMID:10377389</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Hsp100 chaperones ClpB and Hsp104 utilize the energy from ATP hydrolysis to reactivate aggregated proteins in concert with the DnaK/Hsp70 chaperone system, thereby playing an important role in protein quality control. They belong to the family of AAA+ proteins (ATPases associated with various cellular activities), possess two nucleotide binding domains per monomer (NBD1 and NBD2) and oligomerize into hexameric ring complexes. Furthermore, Hsp104 is involved in yeast prion propagation and inheritance. It is well established that low concentrations of guanidinium chloride (GdmCl) inhibit the ATPase activity of Hsp104 leading to so called prion curing, the loss of prion-related phenotypes. Here, we present mechanistic details about the Hsp100 chaperone inhibition by GdmCl using the Hsp104 homolog ClpB from T. thermophilus. Initially, we demonstrate that NBD1 of ClpB, which was previously considered inactive as a separately expressed construct, is a fully active ATPase on its own. Next, we show that only NBD1, but not NBD2, is affected by GdmCl. We present a crystal structure of ClpB NBD1 in complex with GdmCl and ADP, showing that the Gdm+ ion binds specifically to the active site of NBD1. A conserved essential glutamate residue is involved in this interaction. Additionally, Gdm+ interacts directly with the nucleotide, thereby increasing the nucleotide binding affinity of NBD1. We propose that both the interference with the essential glutamate as well as the modulation of nucleotide binding properties in NBD1 is responsible for the GdmCl-specific inhibition of Hsp100 chaperones.

-	~~==About this Structure==~~	+	The molecular mechanism of Hsp100 chaperone inhibition by the prion curing agent guanidinium chloride.,Zeymer C, Werbeck ND, Schlichting I, Reinstein J J Biol Chem. 2013 Jan 22. PMID:23341453<ref>PMID:23341453</ref>
-	~~[[4hse]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]~~. ~~Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4HSE OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Thermus thermophilus hb8]]		[[Category: Thermus thermophilus hb8]]
-	[[Category: Reinstein, J.]]	+	[[Category: Reinstein, J]]
-	[[Category: Schlichting, I.]]	+	[[Category: Schlichting, I]]
-	[[Category: Werbeck, N D.]]	+	[[Category: Werbeck, N D]]
-	[[Category: Zeymer, C.]]	+	[[Category: Zeymer, C]]
	[[Category: Aaa+ protein]]		[[Category: Aaa+ protein]]
	[[Category: Chaperone]]		[[Category: Chaperone]]
	[[Category: Molecular chaperone]]		[[Category: Molecular chaperone]]
	[[Category: Nucleotide binding domain]]		[[Category: Nucleotide binding domain]]

OCA at 22:43, 3 April 2013

2013-04-03T22:43:04Z

←Older revision		Revision as of 22:43, 3 April 2013
Line 1:		Line 1:
-	[[Image:4hse.png\|left\|200px]]
-
	{{STRUCTURE_4hse\| PDB=4hse \| SCENE= }}		{{STRUCTURE_4hse\| PDB=4hse \| SCENE= }}
-
	===Crystal structure of ClpB NBD1 in complex with guanidinium chloride and ADP===		===Crystal structure of ClpB NBD1 in complex with guanidinium chloride and ADP===
-
	{{ABSTRACT_PUBMED_23341453}}		{{ABSTRACT_PUBMED_23341453}}
		+
		+	==Function==
		+	[[http://www.uniprot.org/uniprot/CLPB_THET8 CLPB_THET8]] Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.<ref>PMID:10377389</ref>

	==About this Structure==		==About this Structure==
	[[4hse]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HSE OCA].		[[4hse]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HSE OCA].
		+
		+	==Reference==
		+	<references group="xtra"/><references/>
	[[Category: Thermus thermophilus hb8]]		[[Category: Thermus thermophilus hb8]]
	[[Category: Reinstein, J.]]		[[Category: Reinstein, J.]]

OCA at 09:34, 13 February 2013

2013-02-13T09:34:44Z

←Older revision		Revision as of 09:34, 13 February 2013
Line 1:		Line 1:
-	[[Image:4hse.~~jpg~~\|left\|200px]]	+	[[Image:4hse.png\|left\|200px]]

	{{STRUCTURE_4hse\| PDB=4hse \| SCENE= }}		{{STRUCTURE_4hse\| PDB=4hse \| SCENE= }}
Line 5:		Line 5:
	===Crystal structure of ClpB NBD1 in complex with guanidinium chloride and ADP===		===Crystal structure of ClpB NBD1 in complex with guanidinium chloride and ADP===

		+	{{ABSTRACT_PUBMED_23341453}}

	==About this Structure==		==About this Structure==

OCA at 12:40, 30 January 2013

2013-01-30T12:40:30Z

←Older revision		Revision as of 12:40, 30 January 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4hse.jpg\|left\|200px]]

-	~~The entry~~ 4hse ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_4hse\| PDB=4hse \| SCENE= }}

-	~~Authors: Zeymer, C., Werbeck, N.D., Schlichting, I., Reinstein, J.~~	+	===Crystal structure of ClpB NBD1 in complex with guanidinium chloride and ADP===

-	~~Description:~~ Structure of a ~~molecular~~ chaperone	+
		+	==About this Structure==
		+	[[4hse]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HSE OCA].
		+	[[Category: Thermus thermophilus hb8]]
		+	[[Category: Reinstein, J.]]
		+	[[Category: Schlichting, I.]]
		+	[[Category: Werbeck, N D.]]
		+	[[Category: Zeymer, C.]]
		+	[[Category: Aaa+ protein]]
		+	[[Category: Chaperone]]
		+	[[Category: Molecular chaperone]]
		+	[[Category: Nucleotide binding domain]]

OCA at 06:17, 14 November 2012

2012-11-14T06:17:44Z

←Older revision		Revision as of 06:17, 14 November 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4hse is ON HOLD	+	The entry 4hse is ON HOLD until Paper Publication

	Authors: Zeymer, C., Werbeck, N.D., Schlichting, I., Reinstein, J.		Authors: Zeymer, C., Werbeck, N.D., Schlichting, I., Reinstein, J.

	Description: Structure of a molecular chaperone		Description: Structure of a molecular chaperone

OCA: Protected "4hse" [edit=sysop:move=sysop]

2012-11-08T13:26:20Z

Protected "4hse" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:26, 8 November 2012

OCA: New page: '''Unreleased structure''' The entry 4hse is ON HOLD Authors: Zeymer, C., Werbeck, N.D., Schlichting, I., Reinstein, J. Description: Structure of a molecular chaperone

2012-11-08T13:26:19Z

New page: '''Unreleased structure''' The entry 4hse is ON HOLD Authors: Zeymer, C., Werbeck, N.D., Schlichting, I., Reinstein, J. Description: Structure of a molecular chaperone

New page

'''Unreleased structure'''

The entry 4hse is ON HOLD

Authors: Zeymer, C., Werbeck, N.D., Schlichting, I., Reinstein, J.

Description: Structure of a molecular chaperone