4htv - Revision history

OCA at 11:44, 1 March 2024

2024-03-01T11:44:38Z

←Older revision		Revision as of 11:44, 1 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4htv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Beak_and_feather_disease_virus Beak and feather disease virus] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HTV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HTV FirstGlance]. <br>		<table><tr><td colspan='2'>[[4htv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Beak_and_feather_disease_virus Beak and feather disease virus] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HTV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HTV FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4htv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4htv OCA], [https://pdbe.org/4htv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4htv RCSB], [https://www.ebi.ac.uk/pdbsum/4htv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4htv ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4htv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4htv OCA], [https://pdbe.org/4htv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4htv RCSB], [https://www.ebi.ac.uk/pdbsum/4htv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4htv ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 08:14, 9 November 2022

2022-11-09T08:14:06Z

←Older revision		Revision as of 08:14, 9 November 2022
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	==Mouse importin alpha: BFDV Cap NLS peptide complex==		==Mouse importin alpha: BFDV Cap NLS peptide complex==
-	<StructureSection load='4htv' size='340' side='right' caption='[[4htv]], [[Resolution\|resolution]] 3.00Å' scene=''>	+	<StructureSection load='4htv' size='340' side='right'caption='[[4htv]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4htv]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Lk3_transgenic_mice Lk3 transgenic mice~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HTV OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4HTV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4htv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Beak_and_feather_disease_virus Beak and feather disease virus] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HTV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HTV FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Kpna2, Rch1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4htv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4htv OCA], [https://pdbe.org/4htv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4htv RCSB], [https://www.ebi.ac.uk/pdbsum/4htv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4htv ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4htv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4htv OCA], [~~http~~://pdbe.org/4htv PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4htv RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4htv PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4htv ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~IMA2_MOUSE IMA2_MOUSE]~~] Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.	+	[https://www.uniprot.org/uniprot/IMA1_MOUSE IMA1_MOUSE] Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.

	==See Also==		==See Also==
-	*[[Importin\|Importin]]	+	*[[Importin 3D structures\|Importin 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Lk3 transgenic mice~~]]	+	[[Category: Beak and feather disease virus]]
-	[[Category: ~~Forwood, J K~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Patterson, E I~~]]	+	[[Category: Mus musculus]]
-	[[Category: ~~Raidal, S R~~]]	+	[[Category: Forwood JK]]
-	[[Category: ~~Nuclear transporter~~]]	+	[[Category: Patterson EI]]
-	[[Category: ~~Protein transport-viral protein complex~~]]	+	[[Category: Raidal SR]]

OCA at 21:32, 5 August 2016

2016-08-05T21:32:45Z

←Older revision		Revision as of 21:32, 5 August 2016
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		+
	==Mouse importin alpha: BFDV Cap NLS peptide complex==		==Mouse importin alpha: BFDV Cap NLS peptide complex==
	<StructureSection load='4htv' size='340' side='right' caption='[[4htv]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='4htv' size='340' side='right' caption='[[4htv]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4htv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HTV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HTV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4htv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HTV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HTV FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Kpna2, Rch1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 ~~Mus musculus~~])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Kpna2, Rch1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4htv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4htv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4htv RCSB], [http://www.ebi.ac.uk/pdbsum/4htv PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4htv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4htv OCA], [http://pdbe.org/4htv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4htv RCSB], [http://www.ebi.ac.uk/pdbsum/4htv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4htv ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mus musculus~~]]	+	[[Category: Lk3 transgenic mice]]
	[[Category: Forwood, J K]]		[[Category: Forwood, J K]]
	[[Category: Patterson, E I]]		[[Category: Patterson, E I]]

OCA at 22:05, 25 December 2014

2014-12-25T22:05:07Z

←Older revision		Revision as of 22:05, 25 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4htv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4htv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4htv RCSB], [http://www.ebi.ac.uk/pdbsum/4htv PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4htv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4htv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4htv RCSB], [http://www.ebi.ac.uk/pdbsum/4htv PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/IMA2_MOUSE IMA2_MOUSE]] Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.

	==See Also==		==See Also==

OCA at 09:56, 10 December 2014

2014-12-10T09:56:20Z

←Older revision		Revision as of 09:56, 10 December 2014
Line 1:		Line 1:
-	[[~~Image:~~4htv.~~png~~\|~~left\|200px~~]]	+	==Mouse importin alpha: BFDV Cap NLS peptide complex==
		+	<StructureSection load='4htv' size='340' side='right' caption='[[4htv]], [[Resolution\|resolution]] 3.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4htv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HTV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HTV FirstGlance]. <br>
		+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Kpna2, Rch1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4htv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4htv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4htv RCSB], [http://www.ebi.ac.uk/pdbsum/4htv PDBsum]</span></td></tr>
		+	</table>

-	~~{{STRUCTURE_4htv\| PDB~~=~~4htv \| SCENE= }}~~	+	==See Also==
-		+	*[[Importin\|Importin]]
-	~~===Mouse importin alpha: BFDV Cap NLS peptide complex~~===	+	__TOC__
-		+	</StructureSection>
-		+
-	~~==About this Structure==~~	+
-	[[~~4htv~~]] ~~is a 2 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HTV OCA].~~	+
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Forwood, J K.]]	+	[[Category: Forwood, J K]]
-	[[Category: Patterson, E I.]]	+	[[Category: Patterson, E I]]
-	[[Category: Raidal, S R.]]	+	[[Category: Raidal, S R]]
	[[Category: Nuclear transporter]]		[[Category: Nuclear transporter]]
	[[Category: Protein transport-viral protein complex]]		[[Category: Protein transport-viral protein complex]]

OCA at 10:09, 5 December 2012

2012-12-05T10:09:33Z

←Older revision		Revision as of 10:09, 5 December 2012
Line 1:		Line 1:
-	[[Image:4htv.~~jpg~~\|left\|200px]]	+	[[Image:4htv.png\|left\|200px]]

	{{STRUCTURE_4htv\| PDB=4htv \| SCENE= }}		{{STRUCTURE_4htv\| PDB=4htv \| SCENE= }}
Line 9:		Line 9:
	[[4htv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HTV OCA].		[[4htv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HTV OCA].
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Forwood, J F.]]	+	[[Category: Forwood, J K.]]
	[[Category: Patterson, E I.]]		[[Category: Patterson, E I.]]
	[[Category: Raidal, S R.]]		[[Category: Raidal, S R.]]
	[[Category: Nuclear transporter]]		[[Category: Nuclear transporter]]
	[[Category: Protein transport-viral protein complex]]		[[Category: Protein transport-viral protein complex]]

OCA at 14:40, 28 November 2012

2012-11-28T14:40:58Z

←Older revision		Revision as of 14:40, 28 November 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4htv.jpg\|left\|200px]]

-	~~The entry~~ 4htv ~~is ON HOLD~~	+	{{STRUCTURE_4htv\| PDB=4htv \| SCENE= }}

-	~~Authors~~: ~~Patterson, E.I., Forwood, J.F., Raidal, S.R.~~	+	===Mouse importin alpha: BFDV Cap NLS peptide complex===

-	~~Description~~: ~~Mouse importin alpha~~: ~~BFDV Cap NLS peptide~~ complex	+
		+	==About this Structure==
		+	[[4htv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HTV OCA].
		+	[[Category: Mus musculus]]
		+	[[Category: Forwood, J F.]]
		+	[[Category: Patterson, E I.]]
		+	[[Category: Raidal, S R.]]
		+	[[Category: Nuclear transporter]]
		+	[[Category: Protein transport-viral protein complex]]

OCA: Protected "4htv" [edit=sysop:move=sysop]

2012-11-08T13:27:53Z

Protected "4htv" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:27, 8 November 2012

OCA: New page: '''Unreleased structure''' The entry 4htv is ON HOLD Authors: Patterson, E.I., Forwood, J.F., Raidal, S.R. Description: Mouse importin alpha: BFDV Cap NLS peptide complex

2012-11-08T13:27:52Z

New page: '''Unreleased structure''' The entry 4htv is ON HOLD Authors: Patterson, E.I., Forwood, J.F., Raidal, S.R. Description: Mouse importin alpha: BFDV Cap NLS peptide complex

New page

'''Unreleased structure'''

The entry 4htv is ON HOLD

Authors: Patterson, E.I., Forwood, J.F., Raidal, S.R.

Description: Mouse importin alpha: BFDV Cap NLS peptide complex