4ila - Revision history

OCA at 11:57, 1 March 2024

2024-03-01T11:57:39Z

←Older revision		Revision as of 11:57, 1 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ila]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Gloeobacter_violaceus_PCC_7421 Gloeobacter violaceus PCC 7421]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ILA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ILA FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ila]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Gloeobacter_violaceus_PCC_7421 Gloeobacter violaceus PCC 7421]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ILA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ILA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=PLC:DIUNDECYL+PHOSPHATIDYL+CHOLINE'>PLC</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.5Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=PLC:DIUNDECYL+PHOSPHATIDYL+CHOLINE'>PLC</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ila FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ila OCA], [https://pdbe.org/4ila PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ila RCSB], [https://www.ebi.ac.uk/pdbsum/4ila PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ila ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ila FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ila OCA], [https://pdbe.org/4ila PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ila RCSB], [https://www.ebi.ac.uk/pdbsum/4ila PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ila ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>		[https://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	To understand the molecular mechanism of ion permeation in pentameric ligand-gated ion channels (pLGIC), we solved the structure of an open form of GLIC, a prokaryotic pLGIC, at 2.4 A. Anomalous diffraction data were used to place bound anions and cations. This reveals ordered water molecules at the level of two rings of hydroxylated residues (named Ser6' and Thr2') that contribute to the ion selectivity filter. Two water pentagons are observed, a self-stabilized ice-like water pentagon and a second wider water pentagon, with one sodium ion between them. Single-channel electrophysiology shows that the side-chain hydroxyl of Ser6' is crucial for ion translocation. Simulations and electrostatics calculations complemented the description of hydration in the pore and suggest that the water pentagons observed in the crystal are important for the ion to cross hydrophobic constriction barriers. Simulations that pull a cation through the pore reveal that residue Ser6' actively contributes to ion translocation by reorienting its side chain when the ion is going through the pore. Generalization of these findings to the pLGIC family is proposed.
-
-	Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels.,Sauguet L, Poitevin F, Murail S, Van Renterghem C, Moraga-Cid G, Malherbe L, Thompson AW, Koehl P, Corringer PJ, Baaden M, Delarue M EMBO J. 2013 Feb 12;32(5):728-41. doi: 10.1038/emboj.2013.17. Epub 2013 Feb 12. PMID:23403925<ref>PMID:23403925</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4ila" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 20:53, 16 November 2022

2022-11-16T20:53:59Z

←Older revision		Revision as of 20:53, 16 November 2022
Line 1:		Line 1:

	==The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium==		==The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium==
-	<StructureSection load='4ila' size='340' side='right' caption='[[4ila]], [[Resolution\|resolution]] 3.50Å' scene=''>	+	<StructureSection load='4ila' size='340' side='right'caption='[[4ila]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ila]] is a 5 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Glovi Glovi~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ILA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ILA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ila]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Gloeobacter_violaceus_PCC_7421 Gloeobacter violaceus PCC 7421]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ILA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ILA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=PLC:DIUNDECYL+PHOSPHATIDYL+CHOLINE'>PLC</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=PLC:DIUNDECYL+PHOSPHATIDYL+CHOLINE'>PLC</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4hfi\|4hfi]], [[4il9\|4il9]], [[4il4\|4il4]], [[4ilb\|4ilb]], [[4ilc\|4ilc]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ila FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ila OCA], [https://pdbe.org/4ila PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ila RCSB], [https://www.ebi.ac.uk/pdbsum/4ila PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ila ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glvI, glr4197 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=251221 GLOVI])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ila FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ila OCA], [~~http~~://pdbe.org/4ila PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4ila RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4ila PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4ila ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>	+	[https://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 20:

	==See Also==		==See Also==
-	*[[Ion channels\|Ion channels]]	+	*[[Ion channels 3D structures\|Ion channels 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Glovi~~]]	+	[[Category: Gloeobacter violaceus PCC 7421]]
-	[[Category: ~~Corringer, P J~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Delarue, M~~]]	+	[[Category: Corringer PJ]]
-	[[Category: ~~Sauguet, L~~]]	+	[[Category: Delarue M]]
-	[[Category: ~~Ion channel]]~~	+	[[Category: Sauguet L]]
-	~~[[Category: Membrane]]~~	+
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Pentameric ligand-gated ion channel]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 15:15, 4 August 2016

2016-08-04T15:15:32Z

←Older revision		Revision as of 15:15, 4 August 2016
Line 1:		Line 1:
		+
	==The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium==		==The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium==
	<StructureSection load='4ila' size='340' side='right' caption='[[4ila]], [[Resolution\|resolution]] 3.50Å' scene=''>		<StructureSection load='4ila' size='340' side='right' caption='[[4ila]], [[Resolution\|resolution]] 3.50Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4hfi\|4hfi]], [[4il9\|4il9]], [[4il4\|4il4]], [[4ilb\|4ilb]], [[4ilc\|4ilc]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4hfi\|4hfi]], [[4il9\|4il9]], [[4il4\|4il4]], [[4ilb\|4ilb]], [[4ilc\|4ilc]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glvI, glr4197 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=251221 GLOVI])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glvI, glr4197 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=251221 GLOVI])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ila FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ila OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ila RCSB], [http://www.ebi.ac.uk/pdbsum/4ila PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ila FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ila OCA], [http://pdbe.org/4ila PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ila RCSB], [http://www.ebi.ac.uk/pdbsum/4ila PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ila ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4ila" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Ion channels\|Ion channels]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:28, 25 December 2014

2014-12-25T10:28:25Z

←Older revision		Revision as of 10:28, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ila FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ila OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ila RCSB], [http://www.ebi.ac.uk/pdbsum/4ila PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ila FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ila OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ila RCSB], [http://www.ebi.ac.uk/pdbsum/4ila PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 16:53, 10 December 2014

2014-12-10T16:53:29Z

←Older revision		Revision as of 16:53, 10 December 2014
Line 1:		Line 1:
-	[[~~Image:~~4ila.~~jpg~~\|~~left~~\|~~200px~~]]	+	==The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium==
		+	<StructureSection load='4ila' size='340' side='right' caption='[[4ila]], [[Resolution\|resolution]] 3.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4ila]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Glovi Glovi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ILA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ILA FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=PLC:DIUNDECYL+PHOSPHATIDYL+CHOLINE'>PLC</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4hfi\|4hfi]], [[4il9\|4il9]], [[4il4\|4il4]], [[4ilb\|4ilb]], [[4ilc\|4ilc]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">glvI, glr4197 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=251221 GLOVI])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ila FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ila OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ila RCSB], [http://www.ebi.ac.uk/pdbsum/4ila PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	To understand the molecular mechanism of ion permeation in pentameric ligand-gated ion channels (pLGIC), we solved the structure of an open form of GLIC, a prokaryotic pLGIC, at 2.4 A. Anomalous diffraction data were used to place bound anions and cations. This reveals ordered water molecules at the level of two rings of hydroxylated residues (named Ser6' and Thr2') that contribute to the ion selectivity filter. Two water pentagons are observed, a self-stabilized ice-like water pentagon and a second wider water pentagon, with one sodium ion between them. Single-channel electrophysiology shows that the side-chain hydroxyl of Ser6' is crucial for ion translocation. Simulations and electrostatics calculations complemented the description of hydration in the pore and suggest that the water pentagons observed in the crystal are important for the ion to cross hydrophobic constriction barriers. Simulations that pull a cation through the pore reveal that residue Ser6' actively contributes to ion translocation by reorienting its side chain when the ion is going through the pore. Generalization of these findings to the pLGIC family is proposed.

-	~~{{STRUCTURE_4ila\| PDB=4ila \| SCENE= }}~~	+	Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels.,Sauguet L, Poitevin F, Murail S, Van Renterghem C, Moraga-Cid G, Malherbe L, Thompson AW, Koehl P, Corringer PJ, Baaden M, Delarue M EMBO J. 2013 Feb 12;32(5):728-41. doi: 10.1038/emboj.2013.17. Epub 2013 Feb 12. PMID:23403925<ref>PMID:23403925</ref>

-	~~===The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	==~~About this Structure~~==	+	<references/>
-	~~[[4ila]] is a 5 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Gloeobacter_violaceus_pcc_7421 Gloeobacter violaceus pcc 7421]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ILA OCA].~~	+	__TOC__
-	[[Category: ~~Gloeobacter violaceus pcc 7421~~]]	+	</StructureSection>
-	[[Category: Corringer, P J.]]	+	[[Category: Glovi]]
-	[[Category: Delarue, M.]]	+	[[Category: Corringer, P J]]
-	[[Category: Sauguet, L.]]	+	[[Category: Delarue, M]]
		+	[[Category: Sauguet, L]]
	[[Category: Ion channel]]		[[Category: Ion channel]]
	[[Category: Membrane]]		[[Category: Membrane]]

OCA at 14:01, 20 February 2013

2013-02-20T14:01:27Z

←Older revision		Revision as of 14:01, 20 February 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:4ila.jpg\|left\|200px]]

-	~~The entry~~ 4ila ~~is ON HOLD~~	+	{{STRUCTURE_4ila\| PDB=4ila \| SCENE= }}

-	~~Authors: Sauguet, L., Corringer, P.J., Delarue, M.~~	+	===The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium===

-	~~Description~~: ~~The pentameric~~ ligand-gated ion channel ~~GLIC A237F in complex with Cesium~~	+
		+	==About this Structure==
		+	[[4ila]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Gloeobacter_violaceus_pcc_7421 Gloeobacter violaceus pcc 7421]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ILA OCA].
		+	[[Category: Gloeobacter violaceus pcc 7421]]
		+	[[Category: Corringer, P J.]]
		+	[[Category: Delarue, M.]]
		+	[[Category: Sauguet, L.]]
		+	[[Category: Ion channel]]
		+	[[Category: Membrane]]
		+	[[Category: Membrane protein]]
		+	[[Category: Pentameric ligand-gated ion channel]]
		+	[[Category: Transport protein]]

OCA at 10:04, 13 February 2013

2013-02-13T10:04:55Z

←Older revision		Revision as of 10:04, 13 February 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4ila is ON HOLD ~~until sometime in the future~~	+	The entry 4ila is ON HOLD

	Authors: Sauguet, L., Corringer, P.J., Delarue, M.		Authors: Sauguet, L., Corringer, P.J., Delarue, M.

	Description: The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium		Description: The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium

OCA at 12:01, 30 January 2013

2013-01-30T12:01:50Z

←Older revision		Revision as of 12:01, 30 January 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4ila is ON HOLD	+	The entry 4ila is ON HOLD until sometime in the future

	Authors: Sauguet, L., Corringer, P.J., Delarue, M.		Authors: Sauguet, L., Corringer, P.J., Delarue, M.

	Description: The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium		Description: The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium

OCA: Protected "4ila" [edit=sysop:move=sysop]

2013-01-09T07:51:28Z

Protected "4ila" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:51, 9 January 2013

OCA: New page: '''Unreleased structure''' The entry 4ila is ON HOLD Authors: Sauguet, L., Corringer, P.J., Delarue, M. Description: The pentameric ligand-gated ion channel GLIC A237F in complex with ...

2013-01-09T07:51:27Z

New page: '''Unreleased structure''' The entry 4ila is ON HOLD Authors: Sauguet, L., Corringer, P.J., Delarue, M. Description: The pentameric ligand-gated ion channel GLIC A237F in complex with ...

New page

'''Unreleased structure'''

The entry 4ila is ON HOLD

Authors: Sauguet, L., Corringer, P.J., Delarue, M.

Description: The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium