4j3o - Revision history

OCA at 15:35, 20 September 2023

2023-09-20T15:35:42Z

←Older revision		Revision as of 15:35, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4j3o]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J3O FirstGlance]. <br>		<table><tr><td colspan='2'>[[4j3o]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J3O FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j3o OCA], [https://pdbe.org/4j3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j3o RCSB], [https://www.ebi.ac.uk/pdbsum/4j3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j3o ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.8Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j3o OCA], [https://pdbe.org/4j3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j3o RCSB], [https://www.ebi.ac.uk/pdbsum/4j3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j3o ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 21:30, 16 November 2022

2022-11-16T21:30:45Z

←Older revision		Revision as of 21:30, 16 November 2022
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	==Crystal structure of the FimD usher traversed by the pilus tip complex assembly composed of FimC:FimF:FimG:FimH==		==Crystal structure of the FimD usher traversed by the pilus tip complex assembly composed of FimC:FimF:FimG:FimH==
-	<StructureSection load='4j3o' size='340' side='right' caption='[[4j3o]], [[Resolution\|resolution]] 3.80Å' scene=''>	+	<StructureSection load='4j3o' size='340' side='right'caption='[[4j3o]], [[Resolution\|resolution]] 3.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4j3o]] is a 5 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J3O OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4J3O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4j3o]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J3O FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fimG, b4319, JW4282 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), fimH, b4320, JW4283 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), fimC, b4316, JW4279 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), fimF, b4318, JW4281 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), fimD, b4317, JW5780 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j3o OCA], [https://pdbe.org/4j3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j3o RCSB], [https://www.ebi.ac.uk/pdbsum/4j3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j3o ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4j3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j3o OCA], [~~http~~://pdbe.org/4j3o PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4j3o RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4j3o PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4j3o ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/FIMF_ECOLI FIMF_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Involved in the integration of FimH in the fimbriae. [[http://www.uniprot.org/uniprot/FIMG_ECOLI FIMG_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Involved in the integration of FimH in the fimbriae. [[http://www.uniprot.org/uniprot/FIMC_ECOLI FIMC_ECOLI]] Required for the biogenesis of type 1 fimbriae. Binds and interact with FimH. [[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. [[http://www.uniprot.org/uniprot/FIMD_ECOLI FIMD_ECOLI]] Involved in the export and assembly of FimA fimbrial subunits across the outer membrane.	+	[https://www.uniprot.org/uniprot/FIMG_ECOLI FIMG_ECOLI] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Involved in the integration of FimH in the fimbriae.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 4j3o" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4j3o" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Adhesin 3D structures\|Adhesin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ecoli]]~~	+	[[Category: Escherichia coli K-12]]
-	~~[[Category: Geibel, S]]~~	+	[[Category: Large Structures]]
-	~~[[Category: Waksman, G]]~~	+	[[Category: Geibel S]]
-	~~[[Category: Adhesion]]~~	+	[[Category: Waksman G]]
-	~~[[Category: Bacterial outer membrane]]~~	+
-	~~[[Category: Beta barrel]]~~	+
-	~~[[Category: Cell adhesion-chaperone~~-~~membrane protein complex~~]]	+
-	[[Category: ~~D-mannose-binding~~]]	+
-	[[Category: ~~Immunglobuline-like fold~~]]	+
-	[[Category: ~~Pilus subunit translocation]]~~	+
-	~~[[Category: Type 1 pilus assembly~~]]	+

OCA at 15:57, 4 August 2016

2016-08-04T15:57:53Z

←Older revision		Revision as of 15:57, 4 August 2016
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		+
	==Crystal structure of the FimD usher traversed by the pilus tip complex assembly composed of FimC:FimF:FimG:FimH==		==Crystal structure of the FimD usher traversed by the pilus tip complex assembly composed of FimC:FimF:FimG:FimH==
	<StructureSection load='4j3o' size='340' side='right' caption='[[4j3o]], [[Resolution\|resolution]] 3.80Å' scene=''>		<StructureSection load='4j3o' size='340' side='right' caption='[[4j3o]], [[Resolution\|resolution]] 3.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4j3o]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli_k-12 Escherichia coli k-12] and [http://en.wikipedia.org/wiki/Gekko_coi Gekko coi~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J3O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J3O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4j3o]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J3O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J3O FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fimG, b4319, JW4282 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~1118509 Gekko coi~~]), fimH, b4320, JW4283 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ~~Escherichia coli K-12~~]), fimC, b4316, JW4279 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~1118509 Gekko coi~~]), fimF, b4318, JW4281 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ~~Escherichia coli K-12~~]), fimD, b4317, JW5780 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ~~Escherichia coli K-12~~])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fimG, b4319, JW4282 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), fimH, b4320, JW4283 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), fimC, b4316, JW4279 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), fimF, b4318, JW4281 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), fimD, b4317, JW5780 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j3o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4j3o RCSB], [http://www.ebi.ac.uk/pdbsum/4j3o PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j3o OCA], [http://pdbe.org/4j3o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4j3o RCSB], [http://www.ebi.ac.uk/pdbsum/4j3o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4j3o ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4j3o" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia coli k-12]]~~	+	[[Category: Ecoli]]
-	~~[[Category: Gekko coi~~]]	+
	[[Category: Geibel, S]]		[[Category: Geibel, S]]
	[[Category: Waksman, G]]		[[Category: Waksman, G]]

OCA at 10:48, 25 December 2014

2014-12-25T10:48:02Z

←Older revision		Revision as of 10:48, 25 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4j3o\| PDB=4j3o \| SCENE= }}~~	+	==Crystal structure of the FimD usher traversed by the pilus tip complex assembly composed of FimC:FimF:FimG:FimH==
-	===Crystal structure of the FimD usher traversed by the pilus tip complex assembly composed of FimC:FimF:FimG:FimH===	+	<StructureSection load='4j3o' size='340' side='right' caption='[[4j3o]], [[Resolution\|resolution]] 3.80Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23579681}}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4j3o]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12] and [http://en.wikipedia.org/wiki/Gekko_coi Gekko coi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J3O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J3O FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fimG, b4319, JW4282 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1118509 Gekko coi]), fimH, b4320, JW4283 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 Escherichia coli K-12]), fimC, b4316, JW4279 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1118509 Gekko coi]), fimF, b4318, JW4281 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 Escherichia coli K-12]), fimD, b4317, JW5780 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 Escherichia coli K-12])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j3o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4j3o RCSB], [http://www.ebi.ac.uk/pdbsum/4j3o PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/FIMF_ECOLI FIMF_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Involved in the integration of FimH in the fimbriae. [[http://www.uniprot.org/uniprot/FIMG_ECOLI FIMG_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Involved in the integration of FimH in the fimbriae. [[http://www.uniprot.org/uniprot/FIMC_ECOLI FIMC_ECOLI]] Required for the biogenesis of type 1 fimbriae. Binds and interact with FimH. [[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. [[http://www.uniprot.org/uniprot/FIMD_ECOLI FIMD_ECOLI]] Involved in the export and assembly of FimA fimbrial subunits across the outer membrane.		[[http://www.uniprot.org/uniprot/FIMF_ECOLI FIMF_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Involved in the integration of FimH in the fimbriae. [[http://www.uniprot.org/uniprot/FIMG_ECOLI FIMG_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Involved in the integration of FimH in the fimbriae. [[http://www.uniprot.org/uniprot/FIMC_ECOLI FIMC_ECOLI]] Required for the biogenesis of type 1 fimbriae. Binds and interact with FimH. [[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. [[http://www.uniprot.org/uniprot/FIMD_ECOLI FIMD_ECOLI]] Involved in the export and assembly of FimA fimbrial subunits across the outer membrane.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Type 1 pili, produced by uropathogenic Escherichia coli, are multisubunit fibres crucial in recognition of and adhesion to host tissues. During pilus biogenesis, subunits are recruited to an outer membrane assembly platform, the FimD usher, which catalyses their polymerization and mediates pilus secretion. The recent determination of the crystal structure of an initiation complex provided insight into the initiation step of pilus biogenesis resulting in pore activation, but very little is known about the elongation steps that follow. Here, to address this question, we determine the structure of an elongation complex in which the tip complex assembly composed of FimC, FimF, FimG and FimH passes through FimD. This structure demonstrates the conformational changes required to prevent backsliding of the nascent pilus through the FimD pore and also reveals unexpected properties of the usher pore. We show that the circular binding interface between the pore lumen and the folded substrate participates in transport by defining a low-energy pathway along which the nascent pilus polymer is guided during secretion.
		+
		+	Structural and energetic basis of folded-protein transport by the FimD usher.,Geibel S, Procko E, Hultgren SJ, Baker D, Waksman G Nature. 2013 Apr 11;496(7444):243-6. doi: 10.1038/nature12007. PMID:23579681<ref>PMID:23579681</ref>

-	==~~About this Structure~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[4j3o]] is a 5 chain structure with sequence from [http:~~//en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12] and [http://en.wikipedia.org/wiki/Gekko_coi Gekko coi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J3O OCA].	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli k-12]]		[[Category: Escherichia coli k-12]]
	[[Category: Gekko coi]]		[[Category: Gekko coi]]
-	[[Category: Geibel, S.]]	+	[[Category: Geibel, S]]
-	[[Category: Waksman, G.]]	+	[[Category: Waksman, G]]
	[[Category: Adhesion]]		[[Category: Adhesion]]
	[[Category: Bacterial outer membrane]]		[[Category: Bacterial outer membrane]]

OCA at 10:05, 24 April 2013

2013-04-24T10:05:16Z

←Older revision		Revision as of 10:05, 24 April 2013
Line 1:		Line 1:
	{{STRUCTURE_4j3o\| PDB=4j3o \| SCENE= }}		{{STRUCTURE_4j3o\| PDB=4j3o \| SCENE= }}
	===Crystal structure of the FimD usher traversed by the pilus tip complex assembly composed of FimC:FimF:FimG:FimH===		===Crystal structure of the FimD usher traversed by the pilus tip complex assembly composed of FimC:FimF:FimG:FimH===
		+	{{ABSTRACT_PUBMED_23579681}}

	==Function==		==Function==

OCA at 22:49, 10 April 2013

2013-04-10T22:49:37Z

←Older revision		Revision as of 22:49, 10 April 2013
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_4j3o\| PDB=4j3o \| SCENE= }}
		+	===Crystal structure of the FimD usher traversed by the pilus tip complex assembly composed of FimC:FimF:FimG:FimH===

-	~~The entry 4j3o~~ is ~~ON HOLD~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/FIMF_ECOLI FIMF_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Involved in the integration of FimH in the fimbriae. [[http://www.uniprot.org/uniprot/FIMG_ECOLI FIMG_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Involved in the integration of FimH in the fimbriae. [[http://www.uniprot.org/uniprot/FIMC_ECOLI FIMC_ECOLI]] Required for the biogenesis of type 1 fimbriae. Binds and interact with FimH. [[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. [[http://www.uniprot.org/uniprot/FIMD_ECOLI FIMD_ECOLI]] Involved in the export and assembly of FimA fimbrial subunits across the outer membrane.

-	~~Authors~~: Geibel, S., Waksman, G.	+	==About this Structure==
-		+	[[4j3o]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12] and [http://en.wikipedia.org/wiki/Gekko_coi Gekko coi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J3O OCA].
-	~~Description~~: ~~Crystal structure of the FimD usher traversed by the pilus tip~~ complex ~~assembly composed of FimC~~:~~FimF~~:~~FimG~~:~~FimH~~	+	[[Category: Escherichia coli k-12]]
		+	[[Category: Gekko coi]]
		+	[[Category: Geibel, S.]]
		+	[[Category: Waksman, G.]]
		+	[[Category: Adhesion]]
		+	[[Category: Bacterial outer membrane]]
		+	[[Category: Beta barrel]]
		+	[[Category: Cell adhesion-chaperone-membrane protein complex]]
		+	[[Category: D-mannose-binding]]
		+	[[Category: Immunglobuline-like fold]]
		+	[[Category: Pilus subunit translocation]]
		+	[[Category: Type 1 pilus assembly]]

OCA: Protected "4j3o" [edit=sysop:move=sysop]

2013-02-13T10:11:38Z

Protected "4j3o" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:11, 13 February 2013

OCA: New page: '''Unreleased structure''' The entry 4j3o is ON HOLD Authors: Geibel, S., Waksman, G. Description: Crystal structure of the FimD usher traversed by the pilus tip complex assembly compo...

2013-02-13T10:11:37Z

New page: '''Unreleased structure''' The entry 4j3o is ON HOLD Authors: Geibel, S., Waksman, G. Description: Crystal structure of the FimD usher traversed by the pilus tip complex assembly compo...

New page

'''Unreleased structure'''

The entry 4j3o is ON HOLD

Authors: Geibel, S., Waksman, G.

Description: Crystal structure of the FimD usher traversed by the pilus tip complex assembly composed of FimC:FimF:FimG:FimH