4juo - Revision history

OCA at 15:49, 20 September 2023

2023-09-20T15:49:18Z

←Older revision		Revision as of 15:49, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4juo]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JUO FirstGlance]. <br>		<table><tr><td colspan='2'>[[4juo]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JUO FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LFX:(3S)-9-FLUORO-3-METHYL-10-(4-METHYLPIPERAZIN-1-YL)-7-OXO-2,3-DIHYDRO-7H-[1,4]OXAZINO[2,3,4-IJ]QUINOLINE-6-CARBOXYLIC+ACID'>LFX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 6.53Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LFX:(3S)-9-FLUORO-3-METHYL-10-(4-METHYLPIPERAZIN-1-YL)-7-OXO-2,3-DIHYDRO-7H-[1,4]OXAZINO[2,3,4-IJ]QUINOLINE-6-CARBOXYLIC+ACID'>LFX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4juo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4juo OCA], [https://pdbe.org/4juo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4juo RCSB], [https://www.ebi.ac.uk/pdbsum/4juo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4juo ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4juo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4juo OCA], [https://pdbe.org/4juo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4juo RCSB], [https://www.ebi.ac.uk/pdbsum/4juo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4juo ProSAT]</span></td></tr>
	</table>		</table>

OCA at 11:26, 30 November 2022

2022-11-30T11:26:04Z

←Older revision		Revision as of 11:26, 30 November 2022
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	==A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32==		==A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32==
-	<StructureSection load='4juo' size='340' side='right' caption='[[4juo]], [[Resolution\|resolution]] 6.53Å' scene=''>	+	<StructureSection load='4juo' size='340' side='right'caption='[[4juo]], [[Resolution\|resolution]] 6.53Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4juo]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Strpn Strpn~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4JUO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4juo]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JUO FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LFX:(3S)-9-FLUORO-3-METHYL-10-(4-METHYLPIPERAZIN-1-YL)-7-OXO-2,3-DIHYDRO-7H-[1,4]OXAZINO[2,3,4-IJ]QUINOLINE-6-CARBOXYLIC+ACID'>LFX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LFX:(3S)-9-FLUORO-3-METHYL-10-(4-METHYLPIPERAZIN-1-YL)-7-OXO-2,3-DIHYDRO-7H-[1,4]OXAZINO[2,3,4-IJ]QUINOLINE-6-CARBOXYLIC+ACID'>LFX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4i3h\|4i3h]], [[3rad\|3rad]], [[3rae\|3rae]], [[3raf\|3raf]], [[3ksa\|3ksa]], [[3ksb\|3ksb]], [[3ltn\|3ltn]], [[3k9f\|3k9f]], [[3foe\|3foe]], [[3fof\|3fof]], [[2nov\|2nov]]</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4juo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4juo OCA], [https://pdbe.org/4juo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4juo RCSB], [https://www.ebi.ac.uk/pdbsum/4juo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4juo ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">parC, SP_0855 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=170187 STRPN]), parE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=170187 STRPN])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4juo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4juo OCA], [~~http~~://pdbe.org/4juo PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4juo RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4juo PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4juo ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/PARC_STRPN PARC_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref> [[http://www.uniprot.org/uniprot/PARE_STRPN PARE_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref>	+	[https://www.uniprot.org/uniprot/PARE_STRPN PARE_STRPN] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4juo" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4juo" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Topoisomerase 3D structures\|Topoisomerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Strpn~~]]	+	[[Category: Large Structures]]
-	[[Category: Crevel, I]]	+	[[Category: Streptococcus pneumoniae TIGR4]]
-	[[Category: Fisher~~, L M~~]]	+	[[Category: Crevel I]]
-	[[Category: Laponogov, I]]	+	[[Category: Fisher LM]]
-	[[Category: Pan, X S]]	+	[[Category: Laponogov I]]
-	[[Category: Sanderson~~, M R~~]]	+	[[Category: Pan X-S]]
-	[[Category: Veselkov~~, D A]]~~	+	[[Category: Sanderson MR]]
-	~~[[Category: Atp binding]]~~	+	[[Category: Veselkov DA]]
-	~~[[Category: Full-length pare]]~~	+
-	~~[[Category: Isomerase-dna complex]]~~	+
-	~~[[Category: Open n-gate]]~~	+
-	~~[[Category: Parc55]]~~	+
-	~~[[Category: Topoisomerase iia~~]]	+

OCA at 09:15, 15 November 2017

2017-11-15T09:15:41Z

←Older revision		Revision as of 09:15, 15 November 2017
Line 21:		Line 21:
	</div>		</div>
	<div class="pdbe-citations 4juo" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4juo" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Topoisomerase\|Topoisomerase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 20:10, 5 August 2016

2016-08-05T20:10:41Z

←Older revision		Revision as of 20:10, 5 August 2016
Line 1:		Line 1:
		+
	==A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32==		==A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32==
	<StructureSection load='4juo' size='340' side='right' caption='[[4juo]], [[Resolution\|resolution]] 6.53Å' scene=''>		<StructureSection load='4juo' size='340' side='right' caption='[[4juo]], [[Resolution\|resolution]] 6.53Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">parC, SP_0855 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=170187 STRPN]), parE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=170187 STRPN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">parC, SP_0855 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=170187 STRPN]), parE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=170187 STRPN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4juo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4juo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4juo RCSB], [http://www.ebi.ac.uk/pdbsum/4juo PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4juo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4juo OCA], [http://pdbe.org/4juo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4juo RCSB], [http://www.ebi.ac.uk/pdbsum/4juo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4juo ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4juo" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 05:29, 25 December 2014

2014-12-25T05:29:26Z

←Older revision		Revision as of 05:29, 25 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4juo\| PDB=4juo \| SCENE= }}~~	+	==A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32==
-	===A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32===	+	<StructureSection load='4juo' size='340' side='right' caption='[[4juo]], [[Resolution\|resolution]] 6.53Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23965305}}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4juo]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JUO FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LFX:(3S)-9-FLUORO-3-METHYL-10-(4-METHYLPIPERAZIN-1-YL)-7-OXO-2,3-DIHYDRO-7H-[1,4]OXAZINO[2,3,4-IJ]QUINOLINE-6-CARBOXYLIC+ACID'>LFX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4i3h\|4i3h]], [[3rad\|3rad]], [[3rae\|3rae]], [[3raf\|3raf]], [[3ksa\|3ksa]], [[3ksb\|3ksb]], [[3ltn\|3ltn]], [[3k9f\|3k9f]], [[3foe\|3foe]], [[3fof\|3fof]], [[2nov\|2nov]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">parC, SP_0855 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=170187 STRPN]), parE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=170187 STRPN])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4juo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4juo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4juo RCSB], [http://www.ebi.ac.uk/pdbsum/4juo PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/PARC_STRPN PARC_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref> [[http://www.uniprot.org/uniprot/PARE_STRPN PARE_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref>		[[http://www.uniprot.org/uniprot/PARC_STRPN PARC_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref> [[http://www.uniprot.org/uniprot/PARE_STRPN PARE_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Type II topoisomerases regulate DNA supercoiling and chromosome segregation. They act as ATP-operated clamps that capture a DNA duplex and pass it through a transient DNA break in a second DNA segment via the sequential opening and closure of ATPase-, G-DNA- and C-gates. Here, we present the first 'open clamp' structures of a 3-gate topoisomerase II-DNA complex, the seminal complex engaged in DNA recognition and capture. A high-resolution structure was solved for a (full-length ParE-ParC55)2 dimer of Streptococcus pneumoniae topoisomerase IV bound to two DNA molecules: a closed DNA gate in a B-A-B form double-helical conformation and a second B-form duplex associated with closed C-gate helices at a novel site neighbouring the catalytically important beta-pinwheel DNA-binding domain. The protein N gate is present in an 'arms-wide-open' state with the undimerized N-terminal ParE ATPase domains connected to TOPRIM domains via a flexible joint and folded back allowing ready access both for gate and transported DNA segments and cleavage-stabilizing antibacterial drugs. The structure shows the molecular conformations of all three gates at 3.7 A, the highest resolution achieved for the full complex to date, and illuminates the mechanism of DNA capture and transport by a type II topoisomerase.
		+
		+	Structure of an 'open' clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport.,Laponogov I, Veselkov DA, Crevel IM, Pan XS, Fisher LM, Sanderson MR Nucleic Acids Res. 2013 Aug 21. PMID:23965305<ref>PMID:23965305</ref>

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[4juo]] is~~ a ~~6 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Strpn Strpn]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4JUO OCA].~~	+	</div>

-	==~~Reference~~==	+	==See Also==
-	~~<ref group~~=~~"xtra">PMID:023965305</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	*[[Topoisomerase\|Topoisomerase]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Strpn]]		[[Category: Strpn]]
-	[[Category: Crevel, I.]]	+	[[Category: Crevel, I]]
-	[[Category: Fisher, L M.]]	+	[[Category: Fisher, L M]]
-	[[Category: Laponogov, I.]]	+	[[Category: Laponogov, I]]
-	[[Category: Pan, X S.]]	+	[[Category: Pan, X S]]
-	[[Category: Sanderson, M R.]]	+	[[Category: Sanderson, M R]]
-	[[Category: Veselkov, D A.]]	+	[[Category: Veselkov, D A]]
	[[Category: Atp binding]]		[[Category: Atp binding]]
	[[Category: Full-length pare]]		[[Category: Full-length pare]]

OCA at 06:13, 4 December 2013

2013-12-04T06:13:28Z

←Older revision		Revision as of 06:13, 4 December 2013
Line 7:		Line 7:

	==About this Structure==		==About this Structure==
-	[[4juo]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Gekko_coi Gekko coi] and [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUO OCA].	+	[[4juo]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUO OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:023965305</ref><references group="xtra"/><references/>		<ref group="xtra">PMID:023965305</ref><references group="xtra"/><references/>
-	[[Category: ~~Gekko coi]]~~	+	[[Category: Strpn]]
-	~~[[Category: Streptococcus pneumoniae tigr4~~]]	+
	[[Category: Crevel, I.]]		[[Category: Crevel, I.]]
	[[Category: Fisher, L M.]]		[[Category: Fisher, L M.]]

OCA at 09:12, 4 September 2013

2013-09-04T09:12:09Z

←Older revision		Revision as of 09:12, 4 September 2013
Line 1:		Line 1:
	{{STRUCTURE_4juo\| PDB=4juo \| SCENE= }}		{{STRUCTURE_4juo\| PDB=4juo \| SCENE= }}
	===A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32===		===A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32===
		+	{{ABSTRACT_PUBMED_23965305}}

	==Function==		==Function==
Line 9:		Line 10:

	==Reference==		==Reference==
-	<references group="xtra"/><references/>	+	<ref group="xtra">PMID:023965305</ref><references group="xtra"/><references/>
	[[Category: Gekko coi]]		[[Category: Gekko coi]]
	[[Category: Streptococcus pneumoniae tigr4]]		[[Category: Streptococcus pneumoniae tigr4]]

OCA at 07:38, 28 August 2013

2013-08-28T07:38:48Z

←Older revision		Revision as of 07:38, 28 August 2013
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_4juo\| PDB=4juo \| SCENE= }}
		+	===A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32===

-	~~The entry 4juo~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/PARC_STRPN PARC_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref> [[http://www.uniprot.org/uniprot/PARE_STRPN PARE_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref>

-	~~Authors~~: ~~Laponogov, I~~.~~, Veselkov, D~~.A.~~, Pan, X~~.-S.~~, Crevel, I~~.~~, Fisher, L~~.M.~~, Sanderson, M.R~~.	+	==About this Structure==
		+	[[4juo]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Gekko_coi Gekko coi] and [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUO OCA].

-	~~Description~~: A ~~low~~-~~resolution three~~-gate ~~structure of topoisomerase IV from Streptococcus pneumoniae in space group H32~~	+	==Reference==
		+	<references group="xtra"/><references/>
		+	[[Category: Gekko coi]]
		+	[[Category: Streptococcus pneumoniae tigr4]]
		+	[[Category: Crevel, I.]]
		+	[[Category: Fisher, L M.]]
		+	[[Category: Laponogov, I.]]
		+	[[Category: Pan, X S.]]
		+	[[Category: Sanderson, M R.]]
		+	[[Category: Veselkov, D A.]]
		+	[[Category: Atp binding]]
		+	[[Category: Full-length pare]]
		+	[[Category: Isomerase-dna complex]]
		+	[[Category: Open n-gate]]
		+	[[Category: Parc55]]
		+	[[Category: Topoisomerase iia]]

OCA at 11:23, 19 June 2013

2013-06-19T11:23:07Z

←Older revision		Revision as of 11:23, 19 June 2013
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4juo is ON HOLD	+	The entry 4juo is ON HOLD until Paper Publication

	Authors: Laponogov, I., Veselkov, D.A., Pan, X.-S., Crevel, I., Fisher, L.M., Sanderson, M.R.		Authors: Laponogov, I., Veselkov, D.A., Pan, X.-S., Crevel, I., Fisher, L.M., Sanderson, M.R.

	Description: A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32		Description: A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32

OCA: Protected "4juo" [edit=sysop:move=sysop]

2013-04-04T01:03:28Z

Protected "4juo" [edit=sysop:move=sysop]

←Older revision

Revision as of 01:03, 4 April 2013